Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2135690881', 'doi': 'https://doi.org/10.2174/157016209788348010', 'title': 'Quadruple Nucleos(t)ide Reverse Transcriptase Inhibitors-Only Regimen of Tenofovir Plus Zidovudine/Lamivudine/Abacavir in Heavily Pre-Treated HIV-1 Infected Patients: Salvage Therapy or Backbone Only?', 'display_name': 'Quadruple Nucleos(t)ide Reverse Transcriptase Inhibitors-Only Regimen of Tenofovir Plus Zidovudine/Lamivudine/Abacavir in Heavily Pre-Treated HIV-1 Infected Patients: Salvage Therapy or Backbone Only?', 'publication_year': 2009, 'publication_date': '2009-05-01', 'ids': {'openalex': 'https://openalex.org/W2135690881', 'doi': 'https://doi.org/10.2174/157016209788348010', 'mag': '2135690881', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/19442129'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.2174/157016209788348010', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S203872900', 'display_name': 'Current HIV Research', 'issn_l': '1570-162X', 'issn': ['1570-162X', '1873-4251'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320079', 'host_organization_name': 'Bentham Science Publishers', 'host_organization_lineage': ['https://openalex.org/P4310320079'], 'host_organization_lineage_names': ['Bentham Science Publishers'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5030943230', 'display_name': 'Christoph Stephan', 'orcid': 'https://orcid.org/0000-0003-3777-9006'}, 'institutions': [{'id': 'https://openalex.org/I114090438', 'display_name': 'Goethe University Frankfurt', 'ror': 'https://ror.org/04cvxnb49', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I114090438']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Christoph Stephan', 'raw_affiliation_strings': ['Johann Wolfgang Goethe-University Hospital, HIV Treatment and Clinical Research Unit, Medical Department II, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany.'], 'affiliations': [{'raw_affiliation_string': 'Johann Wolfgang Goethe-University Hospital, HIV Treatment and Clinical Research Unit, Medical Department II, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany.', 'institution_ids': ['https://openalex.org/I114090438']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5069119683', 'display_name': 'Brenda Dauer', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Brenda Dauer', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5047626680', 'display_name': 'Pavel Khaykin', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Pavel Khaykin', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5110036468', 'display_name': 'M. Stuermer', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Martin Stuermer', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5084482226', 'display_name': 'Peter Gute', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Peter Gute', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5021089438', 'display_name': 'Stephan Klauke', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Stephan Klauke', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5066949455', 'display_name': 'Schlomo Staszewski', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I114090438', 'display_name': 'Goethe University Frankfurt', 'ror': 'https://ror.org/04cvxnb49', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I114090438']}], 'countries': ['DE'], 'is_corresponding': True, 'raw_author_name': 'Schlomo Staszewski', 'raw_affiliation_strings': ['HIV Treatment and Clinical Research Unit, Building D, Hospital of the Johann Wolfgang Goethe University Frankfurt, Theodor-Stern-Kai 7, D-60590 Frankfurt, Germany.,Germany'], 'affiliations': [{'raw_affiliation_string': 'HIV Treatment and Clinical Research Unit, Building D, Hospital of the Johann Wolfgang Goethe University Frankfurt, Theodor-Stern-Kai 7, D-60590 Frankfurt, Germany.,Germany', 'institution_ids': ['https://openalex.org/I114090438']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5066949455'], 'corresponding_institution_ids': ['https://openalex.org/I114090438'], 'apc_list': None, 'apc_paid': None, 'fwci': 0.823, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 10, 'citation_normalized_percentile': {'value': 0.62923, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 84, 'max': 85}, 'biblio': {'volume': '7', 'issue': '3', 'first_page': '320', 'last_page': '326'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10526', 'display_name': 'HIV/AIDS drug development and treatment', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10526', 'display_name': 'HIV/AIDS drug development and treatment', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10112', 'display_name': 'HIV Research and Treatment', 'score': 0.9823, 'subfield': {'id': 'https://openalex.org/subfields/2406', 'display_name': 'Virology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11157', 'display_name': 'Chronic Lymphocytic Leukemia Research', 'score': 0.9768, 'subfield': {'id': 'https://openalex.org/subfields/2716', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/abacavir', 'display_name': 'Abacavir', 'score': 0.96974266}, {'id': 'https://openalex.org/keywords/regimen', 'display_name': 'Regimen', 'score': 0.7300731}, {'id': 'https://openalex.org/keywords/reverse-transcriptase-inhibitor', 'display_name': 'Reverse-transcriptase inhibitor', 'score': 0.68202984}, {'id': 'https://openalex.org/keywords/nucleoside-analogue', 'display_name': 'Nucleoside analogue', 'score': 0.41489446}], 'concepts': [{'id': 'https://openalex.org/C2779465607', 'wikidata': 'https://www.wikidata.org/wiki/Q304330', 'display_name': 'Abacavir', 'level': 5, 'score': 0.96974266}, {'id': 'https://openalex.org/C2777869810', 'wikidata': 'https://www.wikidata.org/wiki/Q422631', 'display_name': 'Lamivudine', 'level': 4, 'score': 0.9303458}, {'id': 'https://openalex.org/C2780216070', 'wikidata': 'https://www.wikidata.org/wiki/Q198504', 'display_name': 'Zidovudine', 'level': 4, 'score': 0.9211517}, {'id': 'https://openalex.org/C2781413609', 'wikidata': 'https://www.wikidata.org/wiki/Q7308373', 'display_name': 'Regimen', 'level': 2, 'score': 0.7300731}, {'id': 'https://openalex.org/C2777351918', 'wikidata': 'https://www.wikidata.org/wiki/Q421559', 'display_name': 'Reverse-transcriptase inhibitor', 'level': 5, 'score': 0.68202984}, {'id': 'https://openalex.org/C159047783', 'wikidata': 'https://www.wikidata.org/wiki/Q7215', 'display_name': 'Virology', 'level': 1, 'score': 0.62998354}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.6061923}, {'id': 'https://openalex.org/C156719811', 'wikidata': 'https://www.wikidata.org/wiki/Q28774', 'display_name': 'Reverse transcriptase', 'level': 4, 'score': 0.56377786}, {'id': 'https://openalex.org/C2909970146', 'wikidata': 'https://www.wikidata.org/wiki/Q421559', 'display_name': 'Nucleoside Reverse Transcriptase Inhibitor', 'level': 5, 'score': 0.4989214}, {'id': 'https://openalex.org/C2777333352', 'wikidata': 'https://www.wikidata.org/wiki/Q2689559', 'display_name': 'Nucleoside analogue', 'level': 3, 'score': 0.41489446}, {'id': 'https://openalex.org/C90924648', 'wikidata': 'https://www.wikidata.org/wiki/Q120569', 'display_name': 'Gastroenterology', 'level': 1, 'score': 0.38352585}, {'id': 'https://openalex.org/C2776543447', 'wikidata': 'https://www.wikidata.org/wiki/Q28734', 'display_name': 'Nucleoside', 'level': 2, 'score': 0.38149813}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.37664533}, {'id': 'https://openalex.org/C142462285', 'wikidata': 'https://www.wikidata.org/wiki/Q2528140', 'display_name': 'Viral load', 'level': 3, 'score': 0.3642922}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.33599037}, {'id': 'https://openalex.org/C2522874641', 'wikidata': 'https://www.wikidata.org/wiki/Q808', 'display_name': 'Virus', 'level': 2, 'score': 0.21426868}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.19843373}, {'id': 'https://openalex.org/C2780727368', 'wikidata': 'https://www.wikidata.org/wiki/Q1928978', 'display_name': 'Viral disease', 'level': 3, 'score': 0.17170951}, {'id': 'https://openalex.org/C2993143319', 'wikidata': 'https://www.wikidata.org/wiki/Q583050', 'display_name': 'Antiretroviral therapy', 'level': 4, 'score': 0.112941295}, {'id': 'https://openalex.org/C49105822', 'wikidata': 'https://www.wikidata.org/wiki/Q176996', 'display_name': 'Polymerase chain reaction', 'level': 3, 'score': 0.06309834}, {'id': 'https://openalex.org/C2780593183', 'wikidata': 'https://www.wikidata.org/wiki/Q6844', 'display_name': 'Hepatitis B virus', 'level': 3, 'score': 0.03688252}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000225', 'descriptor_name': 'Adenine', 'qualifier_ui': 'Q000031', 'qualifier_name': 'analogs & derivatives', 'is_major_topic': True}, {'descriptor_ui': 'D019380', 'descriptor_name': 'Anti-HIV Agents', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D015224', 'descriptor_name': 'Dideoxynucleosides', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D015658', 'descriptor_name': 'HIV Infections', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D019259', 'descriptor_name': 'Lamivudine', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D063065', 'descriptor_name': 'Organophosphonates', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D016879', 'descriptor_name': 'Salvage Therapy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D015215', 'descriptor_name': 'Zidovudine', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D000225', 'descriptor_name': 'Adenine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000225', 'descriptor_name': 'Adenine', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D019943', 'descriptor_name': 'Amino Acid Substitution', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019943', 'descriptor_name': 'Amino Acid Substitution', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D019380', 'descriptor_name': 'Anti-HIV Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018791', 'descriptor_name': 'CD4 Lymphocyte Count', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015224', 'descriptor_name': 'Dideoxynucleosides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015658', 'descriptor_name': 'HIV Infections', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015658', 'descriptor_name': 'HIV Infections', 'qualifier_ui': 'Q000821', 'qualifier_name': 'virology', 'is_major_topic': False}, {'descriptor_ui': 'D054303', 'descriptor_name': 'HIV Reverse Transcriptase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D054303', 'descriptor_name': 'HIV Reverse Transcriptase', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D015497', 'descriptor_name': 'HIV-1', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015497', 'descriptor_name': 'HIV-1', 'qualifier_ui': 'Q000302', 'qualifier_name': 'isolation & purification', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019259', 'descriptor_name': 'Lamivudine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020125', 'descriptor_name': 'Mutation, Missense', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D063065', 'descriptor_name': 'Organophosphonates', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012189', 'descriptor_name': 'Retrospective Studies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000068698', 'descriptor_name': 'Tenofovir', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016896', 'descriptor_name': 'Treatment Outcome', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019562', 'descriptor_name': 'Viral Load', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015215', 'descriptor_name': 'Zidovudine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.2174/157016209788348010', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S203872900', 'display_name': 'Current HIV Research', 'issn_l': '1570-162X', 'issn': ['1570-162X', '1873-4251'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320079', 'host_organization_name': 'Bentham Science Publishers', 'host_organization_lineage': ['https://openalex.org/P4310320079'], 'host_organization_lineage_names': ['Bentham Science Publishers'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/19442129', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.81}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W4253533861', 'https://openalex.org/W347553799', 'https://openalex.org/W28488281', 'https://openalex.org/W2583731600', 'https://openalex.org/W2410191512', 'https://openalex.org/W2318272070', 'https://openalex.org/W2034844651', 'https://openalex.org/W2008093637', 'https://openalex.org/W1985504131', 'https://openalex.org/W1577104482'], 'abstract_inverted_index': {'We': [0], 'investigated': [1], 'the': [2, 51, 64, 92, 149, 156, 199], 'virologic': [3, 69, 94, 146], 'and': [4, 20, 115], 'immunologic': [5], 'responses': [6], 'to': [7, 55, 78, 88, 118, 209], 'a': [8, 109, 216], 'mono-class,': [9], 'nucleoside/nucleotide': [10], 'reverse': [11, 128, 168, 193, 222], 'transcriptase': [12, 129, 169, 194, 223], 'inhibitor': [13, 170, 195], '-': [14], 'combination': [15, 150], 'therapy': [16, 23, 163, 213], 'consisting': [17], 'of': [18, 27, 50, 145, 155, 218], 'tenofovir': [19, 117], 'zidovudine/lamivudine/abacavir': [21, 57, 162, 212], 'in': [22, 198], 'experienced': [24, 68], 'patients.Retrospective': [25], 'study': [26], '122': [28], 'patients.': [29, 141], 'Primary': [30], 'analysis': [31], 'was': [32, 39, 148, 242], 'performed': [33], 'at': [34, 81, 113, 186], '48': [35], 'weeks.': [36], 'Virologic': [37], 'response': [38, 208], 'defined': [40], 'as': [41], 'viral': [42, 75, 227], 'load': [43, 76], 'levels': [44], 'less': [45], 'than': [46], '400': [47], 'copies/ml.About': [48], 'half': [49, 66], 'patients': [52, 98, 104, 122, 157, 181], 'had': [53, 67, 106, 185], 'switched': [54, 124], 'tenofovir+': [56, 161, 211], 'for': [58, 139, 236], 'simplification': [59], 'purposes': [60], 'or': [61, 133], 'toxicity': [62], 'while': [63], 'other': [65], 'failure.': [70], '80/122': [71], '(66%)': [72], 'responded.': [73, 120], 'Median': [74], 'decreased': [77], '78': [79], 'copies/ml': [80], 'week': [82, 101], '48;': [83], 'median': [84, 190], 'CD4': [85, 231], 'count': [86, 232], 'increased': [87], '321': [89], 'cells/mm(3).': [90], 'Of': [91], '42': [93], 'failures,': [95], 'only': [96, 143], '3': [97, 188], 'failed': [99, 159], 'after': [100], '24.': [102], '24/35': [103], 'who': [105, 123, 158], 'been': [107], 'on': [108, 160], 'non-suppressive': [110], 'zidovudine/lamivudine/abacavir-only': [111], 'regimen': [112, 131], 'baseline': [114, 226, 230], 'added': [116], 'intensify,': [119], '41/53': [121], 'from': [125], 'any': [126], 'nucleoside': [127, 167, 192, 204, 221], 'inhibitor-only': [130], 'improved': [132], 'maintained': [134], 'suppression.': [135], 'Genotypes': [136], 'were': [137, 233], 'available': [138], '85/122': [140], 'The': [142], 'predictor': [144], 'failure': [147, 219], '41L+210W+215Y/F': [151, 239], 'mutational': [152, 240], 'pattern.': [153], '16': [154], 'selected': [164], 'new': [165], 'primary': [166], 'resistance': [171], 'mutations': [172, 197], 'that': [173], 'they': [174], 'previously': [175], 'did': [176], 'not': [177], 'have.': [178], '48/85': [179], '(56%)': [180], 'with': [182, 203, 220, 245], 'genotype': [183], 'tests': [184], 'least': [187], '(3-10;': [189], '4)': [191], 'resistance-associated': [196], 'past.Patients': [200], 'heavily': [201], 'pre-treated': [202], 'analogues': [205], 'may': [206], 'show': [207], 'mono-class': [210], 'despite': [214], 'having': [215], 'history': [217], 'inhibitors.': [224], 'Lower': [225], 'load,': [228], 'higher': [229], 'significant': [234], 'predictors': [235], 'response.': [237], 'Archived': [238], 'pattern': [241], 'significantly': [243], 'associated': [244], 'non-response.': [246]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2135690881', 'counts_by_year': [{'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 2}, {'year': 2013, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2024-12-17T12:42:28.966308', 'created_date': '2016-06-24'}