Publication Information

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2810, 2821, 3033, 3051, 3066, 3089, 3117, 3143, 3179, 3205, 3354, 3710, 3744, 3802, 4020, 4228], 'phagocyte-type': [1, 203, 506], 'NADPH': [2, 186, 204, 388, 507, 661, 668, 961, 1384, 1416, 1512, 1701, 1725, 2019, 3736, 3800, 3990, 4138], 'oxidase': [3, 48, 66, 187, 205, 250, 268, 389, 508, 662, 669, 1194, 1385, 1417, 1480, 1495, 1513, 1537, 1702, 1713, 1726, 2020, 3198, 3737, 4083], 'expressed': [4, 206, 2862, 4011], 'in': [5, 13, 21, 55, 73, 114, 135, 167, 175, 188, 207, 215, 223, 257, 275, 316, 337, 369, 377, 390, 453, 496, 671, 696, 971, 985, 995, 1197, 1206, 1214, 1233, 1370, 1403, 1459, 1479, 1528, 1541, 1603, 1621, 1703, 1727, 1812, 1844, 1857, 1862, 1929, 2398, 2414, 2445, 2508, 2641, 2658, 2691, 2742, 2774, 2836, 2900, 2973, 3005, 3159, 3173, 3213, 3248, 3361, 3372, 3380, 3389, 3400, 3409, 3508, 3633, 3646, 3693, 3808, 3831, 3956, 4100, 4114, 4124, 4143, 4176, 4250, 4259], 'endothelial': [6, 57, 190, 208, 259, 392, 420, 423, 427, 497, 660, 697, 870, 930, 934, 939, 960, 986, 1207, 1234, 1381, 1404, 1511, 1623, 1705, 1729, 1772, 1778, 1830, 1886, 2347, 2950, 3838], 'cells': [7, 191, 209, 393, 405, 498, 698, 931, 935, 940, 987, 1208, 1235, 1405, 1706, 1730, 1773, 1779, 1831, 1940, 1957, 2348, 2383, 2736, 2873, 2951], 'differs': [8, 210], 'from': [9, 211, 1409, 1753, 1767, 1959, 2003, 2037, 2208, 2228, 2241, 2277, 2283, 2300, 3189, 3474, 3517, 3791, 4181, 4239], 'the': [10, 22, 43, 64, 83, 98, 110, 115, 136, 168, 178, 185, 200, 212, 224, 245, 266, 285, 300, 312, 317, 338, 370, 380, 387, 402, 454, 659, 666, 674, 678, 869, 957, 963, 996, 1192, 1201, 1230, 1371, 1394, 1401, 1464, 1472, 1489, 1499, 1510, 1524, 1529, 1580, 1639, 1666, 1690, 1696, 1700, 1710, 1724, 1740, 1944, 1960, 2013, 2223, 2317, 2469, 2675, 2682, 2760, 2864, 2901, 3149, 3167, 3208, 3222, 3227, 3237, 3268, 3295, 3305, 3373, 3381, 3390, 3401, 3489, 3532, 3724, 3772, 3785, 3796, 3815, 3988, 4001, 4046, 4059, 4063, 4144, 4182, 4191, 4244], 'neutrophil': [11, 179, 213, 381, 883, 958, 1193, 1361, 1383, 1415, 1457], 'enzyme': [12, 54, 214, 256, 680, 1402, 1585, 3244, 3407], 'that': [14, 156, 216, 358, 672, 868, 981, 1393, 1410, 1477, 1509, 1627, 1719, 2636, 2858, 3367], 'it': [15, 28, 217, 230, 1502], 'exhibits': [16, 218, 965], 'low': [17, 219, 992], 'level': [18, 220, 695, 955, 993], 'activity': [19, 221, 1204, 1600, 3199, 3257, 3278, 3284, 3369, 3378, 3386, 3396, 3408, 3738], 'even': [20, 222, 994], 'absence': [23, 225, 997, 4147], 'of': [24, 46, 63, 88, 97, 109, 123, 145, 184, 226, 248, 265, 290, 299, 311, 325, 347, 386, 456, 493, 677, 968, 973, 998, 1229, 1400, 1428, 1583, 1673, 1693, 1695, 1699, 1723, 1917, 2043, 2087, 2135, 2249, 2502, 2602, 2714, 2801, 2918, 3015, 3023, 3091, 3107, 3119, 3135, 3145, 3176, 3207, 3224, 3226, 3236, 3242, 3274, 3307, 3316, 3336, 3351, 3356, 3405, 3412, 3649, 3700, 3723, 3735, 3798, 3811, 3826, 4022, 4042, 4058, 4148, 4196, 4254], 'agonist': [25, 227], 'stimulation,': [26, 228, 2309], 'and': [27, 50, 71, 90, 104, 107, 143, 161, 229, 252, 273, 292, 306, 309, 345, 363, 447, 450, 461, 686, 693, 864, 873, 959, 1200, 1382, 1397, 1431, 1435, 1445, 1469, 1488, 1612, 1685, 1707, 1749, 1764, 1775, 1808, 1823, 1846, 1892, 1921, 1931, 2022, 2078, 2080, 2124, 2129, 2202, 2215, 2222, 2257, 2294, 2368, 2394, 2435, 2472, 2527, 2531, 2547, 2564, 2569, 2599, 2653, 2674, 2709, 2731, 2740, 2753, 2762, 2790, 2796, 2830, 2860, 2874, 2894, 2958, 2968, 2995, 3020, 3083, 3112, 3138, 3162, 3216, 3281, 3294, 3327, 3434, 3444, 3454, 3480, 3494, 3523, 3537, 3555, 3636, 3683, 3747, 3771, 3814, 3978, 3983, 3993, 4010, 4137, 4152, 4190, 4233, 4281], 'generates': [29, 231], 'intracellular': [30, 86, 196, 232, 288, 398, 1239, 1635, 1735], 'reactive': [31, 147, 233, 349, 407, 924], 'oxygen': [32, 148, 234, 350, 408, 416, 925], 'species.': [33, 235], 'mechanisms': [35, 237, 1376], 'underlying': [36, 238], 'these': [37, 239, 1378, 1572, 1591, 3357], 'differences': [38, 240, 970, 1379], 'are': [39, 241, 451, 688, 877, 1386, 1492, 3359, 3470, 3513], 'unknown.': [40, 242, 1387], 'We': [41, 243], 'studied': [42, 244, 1942], 'subcellular': [44, 93, 246, 295, 1398, 1683, 1691, 2919, 3229, 3410], 'location': [45, 247, 1399, 1582, 1614, 1647, 1692], '(a)': [47, 249, 1689, 4062], 'subunits': [49, 251, 1466, 1491, 1589, 1629, 2021], '(b)': [51, 253, 1708, 4069], 'functionally': [52, 254], 'active': [53, 255], 'unstimulated': [56, 189, 258, 391, 1604, 1728], 'cells.': [58, 260, 1605, 3050], 'Confocal': [59, 261, 2511], 'microscopy': [60, 262, 1620, 2512], 'revealed': [61, 263], 'co-localization': [62, 264], 'major': [65, 267, 491], 'subunits,i.e.': [67, 269], 'gp91phox,': [68, 158, 270, 360, 682], 'p22phox,': [69, 102, 157, 271, 304, 359, 683], 'p47phox,': [70, 159, 272, 361, 684, 1442, 2076], 'p67phox,': [72, 103, 160, 274, 305, 362, 685, 1443, 2077], 'a': [74, 164, 181, 194, 276, 366, 383, 396, 505, 656, 953, 966, 991, 1226, 1419, 1426, 1475, 1517, 1607, 1633, 1643, 1671, 1720, 1733, 2007, 2034, 2082, 2130, 2289, 2313, 2516, 2541, 2552, 2818, 2961, 3105, 3133, 3185, 3240, 3252, 3261, 3509, 3768, 3822, 3940, 4039, 4081, 4090, 4172, 4251], 'mainly': [75, 277, 1644, 1738], 'perinuclear': [76, 278], 'distribution.': [77, 279], 'Plasma': [78, 280], 'membrane': [79, 281, 1543, 1646, 1680, 2866, 3139, 3254], 'biotinylation': [80, 282, 2598, 2899], 'experiments': [81, 283], 'confirmed': [82, 284, 1909, 4027], 'predominantly': [84, 286, 1518, 1634], '(>90%)': [85, 287, 879], 'distribution': [87, 289], 'gp91phox': [89, 99, 291, 301, 874, 1433, 1613, 2136, 2295, 2861], 'p22phox.': [91, 293], 'After': [92, 294, 2680], 'protein': [94, 296, 694, 1681, 2250, 2275, 2298, 2597, 2898, 3152, 3180, 3209, 3551, 3817, 3827, 3840, 3952, 4108, 4178, 4231, 4236, 4294], 'fractionation,': [95, 297, 1684], '∼50%': [96, 122, 298, 324], '(91-kDa': [100, 302], 'band),': [101, 303], 'p40phox': [105, 307], 'pools': [106, 308], '∼30%': [108, 310], 'p47phox': [111, 313, 2122], 'were': [112, 314, 1751, 1766, 1781, 1810, 1833, 1855, 1900, 1941, 1953, 1958, 1966, 2001, 2025, 2089, 2138, 2206, 2227, 2251, 2264, 2322, 2349, 2362, 2384, 2407, 2423, 2466, 2522, 2529, 2566, 2586, 2605, 2645, 2704, 2737, 2746, 2771, 2823, 2844, 2867, 2883, 2952, 2966, 3000, 3157, 3194, 3211, 3246, 3287, 3300, 3483, 3526, 3630, 3644, 3688, 3750, 3829, 3954, 3998, 4054, 4141, 4207, 4241, 4257, 4286], 'present': [113, 315, 1527, 1667], '1475': [116, 137, 318, 339, 3061], '×': [117, 138, 319, 340, 1554, 2750, 2881, 2971, 3040, 3077, 3101, 3129, 3642, 3756], 'g': [118, 139, 320, 341, 1555, 3041, 3078, 3102, 3130, 3757], '(“nucleus-rich”)': [119, 321], 'fraction.': [120, 140, 170, 322, 342, 372, 3250, 3353, 3383], 'Likewise,': [121, 323], 'total': [124, 326], 'NADPH-dependent': [125, 146, 327, 348, 982, 1533, 3197], 'O2⨪production': [126, 328, 1534, 3836, 4175], '(assessed': [127, 329], 'by': [128, 330, 1001, 1617, 1784, 1910, 1970, 2092, 2141, 2482, 2593, 3002, 3009, 3058, 3200, 3638, 3690, 3697, 3739, 3752, 3837, 4029, 4165], 'lucigenin': [129, 331, 3201, 3846, 3995], '(5': [130, 332, 1872, 2497, 3661, 3847, 3996], 'μm)': [131, 333, 3682, 3848, 3992, 3997, 4136, 4140], 'chemiluminescence)': [132, 334], 'was': [133, 335, 1615, 1908, 2033, 2240, 2286, 2310, 2480, 2499, 2513, 2538, 2549, 2663, 2672, 2678, 2685, 2757, 2815, 2914, 3035, 3056, 3069, 3094, 3122, 3182, 3258, 3370, 3387, 3397, 3559, 3714, 3731, 3765, 3778, 3793, 3805, 3819, 3842, 4008, 4026, 4098, 4122, 4163, 4179], 'found': [134, 336, 502, 1626], 'Co-immunoprecipitation': [141, 343, 4205], 'studies': [142, 344, 651, 978, 4206], 'measurement': [144, 346, 3734], 'species': [149, 351, 409, 926], 'production': [150, 352, 495, 984], '(cytochrome': [151, 353], 'c': [152, 354, 3741, 3852, 4104, 4161, 4198, 4201], 'reduction': [153, 355, 3742, 3853, 4105, 4162], 'assay)': [154, 356], 'demonstrated': [155, 357], 'p40phoxexisted': [162, 364], 'as': [163, 193, 365, 395, 434, 459, 1546, 1732, 2026, 2288, 2312, 2324, 2468, 2505, 2607, 2793, 2904, 3289, 3485, 3528, 3561, 3855, 4012], 'functional': [165, 367, 1212, 1584, 1711, 1734], 'complex': [166, 197, 368, 399, 670, 1736], 'cytoskeletal': [169, 371], 'These': [171, 373], 'results': [172, 374, 1478, 1717, 3355], 'indicate': [173, 375, 1718], 'that,': [174, 376, 654], 'contrast': [176, 378], 'to': [177, 379, 503, 665, 881, 1237, 1368, 1461, 1468, 1631, 1638, 1687, 1836, 1968, 2012, 2259, 2379, 2443, 2581, 2849, 2869, 3045, 3079, 3103, 3131, 3234, 3267, 3304, 3767, 3783, 4044, 4199, 4293], 'enzyme,': [180, 382], 'substantial': [182, 384, 1227, 1721], 'proportion': [183, 385, 1228, 1722, 3722], 'exists': [192, 394, 1731], 'preassembled': [195, 397], 'associated': [198, 400, 1737], 'with': [199, 401, 1471, 1523, 1739, 1815, 1866, 1972, 2266, 2355, 2365, 2370, 2377, 2386, 2409, 2425, 2432, 2438, 2447, 2540, 2551, 2648, 2687, 2700, 2707, 2798, 2827, 2832, 2840, 2885, 2955, 3232, 3271, 3376, 3502, 3545, 3625, 3780, 4056, 4186, 4289], 'cytoskeleton.': [201, 403, 1741], 'Endothelial': [404, 1755, 1905], 'generate': [406], '(ROS)': [410], '1The': [411], 'abbreviations': [412], 'used': [413, 1670, 1901, 2287, 2311, 2467, 2500, 2915, 3217, 3288, 3484, 3527, 3939, 4242], 'are:': [414], 'ROSreactive': [415], 'speciesPIECporcine': [417], 'iliac': [418, 928, 1770], 'arterial': [419, 929, 1771], 'cellsBAECbovine': [421], 'aortic': [422, 933, 1777], 'cellsHUVEChuman': [424], 'umbilical': [425, 937, 1828], 'vein': [426, 938, 1829], 'cellsl-NAMEN-ω-nitro-l-arginine': [428], 'methyl': [429, 942, 4075], 'esterTRITCtetramethylrhodamine': [430], 'isothiocyanatePBSphosphate-buffered': [431], 'saline': [432, 947], 'such': [433, 458, 1545], 'O2⨪and': [435], 'H2O2,': [436], 'which': [437, 1588], 'may': [438, 442, 1406], 'inactivate': [439], 'nitric': [440], 'oxide,': [441], 'modulate': [443], 'redox-sensitive': [444], 'signaling': [445], 'pathways': [446], 'gene': [448], 'expression,': [449], 'implicated': [452], 'pathophysiology': [455], 'disorders': [457], 'hypercholesterolemia': [460], 'atherosclerosis': [462], '(1Kunsch': [463], 'C.': [464, 603, 611, 720, 728, 1085, 1093, 1268, 1276, 3601], 'Medford': [465], 'R.M.': [466, 583, 1065, 1248, 2185, 3575], 'Circ.': [467, 588, 618, 640, 735, 757, 897, 1070, 1100, 1122, 1253, 1283, 1305, 1331, 1350], 'Res.': [468, 567, 589, 619, 641, 708, 736, 758, 898, 1049, 1071, 1101, 1123, 1254, 1284, 1306, 1332, 1351], '1999;': [469, 1219, 1450, 2621, 3617], '85:': [470, 1334, 2167], '753-766Crossref': [471], 'PubMed': [472, 485, 517, 553, 593, 623, 645, 740, 762, 790, 820, 902, 1035, 1075, 1105, 1127, 1155, 1185, 1222, 1258, 1288, 1310, 1355, 1453, 1568, 1802, 2111, 2169, 2196, 2341, 2629, 3586, 3620, 3881, 3909, 3930, 4225], 'Scopus': [473, 486, 518, 554, 571, 594, 624, 646, 712, 741, 763, 791, 821, 858, 903, 920, 1036, 1053, 1076, 1106, 1128, 1156, 1186, 1259, 1289, 1311, 1336, 1356, 1661, 1803, 2112, 2170, 2197, 2342, 2630, 3587, 3621, 3882, 3910, 3931], '(740)': [474], 'Google': [475, 488, 520, 534, 556, 573, 596, 626, 648, 714, 743, 765, 793, 823, 843, 860, 905, 922, 1016, 1038, 1055, 1078, 1108, 1130, 1158, 1188, 1223, 1261, 1291, 1313, 1338, 1358, 1454, 1569, 1663, 1805, 1852, 1937, 1996, 2068, 2114, 2172, 2199, 2344, 2632, 2947, 3589, 3623, 3884, 3912, 3933, 4226], 'Scholar,': [476, 521, 535, 557, 574, 597, 627, 744, 766, 794, 824, 844, 906, 1017, 1039, 1056, 1079, 1109, 1131, 1159, 1262, 1292, 1314, 1339, 2173, 2936, 3590, 3885, 3913], '2Harrison': [477], 'D.G.': [478, 510], 'J.': [479, 511, 529, 545, 779, 838, 1011, 1027, 1144, 1563, 1785, 1979, 1990, 2059, 2104, 2105, 2162, 2163, 2190, 2331, 2618, 2942, 3312, 3332, 3580, 3593, 3611, 3614, 3870, 3895, 3898, 3920, 4220], 'Clin.': [480, 512, 2164, 2191, 3581], 'Invest.': [481, 513, 2165, 2192, 3582], '1997;': [482, 514, 568, 709, 1050, 2108, 2335], '100:': [483, 515], '2153-2157Crossref': [484, 516], '(901)': [487, 519], 'Scholar).': [489, 649, 861, 923, 1189, 1224, 1455, 1570, 1664, 1806, 1853, 1938, 1997, 2069, 2115, 2200, 2345, 2633, 2948, 3934, 4227], 'A': [490, 2717, 3721], 'source': [492], 'ROS': [494, 983, 1231], 'has': [499, 1209, 1503], 'recently': [500], 'been': [501, 1504], 'be': [504, 1238, 1407, 2582], '(2Harrison': [509], '3Mohazzab-H': [522], 'K.M.': [523, 1005, 2938], 'Kaminski': [524, 1006], 'P.M.': [525, 543, 1007, 1025, 3595], 'Wolin': [526, 1008, 2939], 'M.S.': [527, 1009, 2940], 'Am.': [528, 544, 837, 1010, 1026, 1562, 2941, 4219], 'Physiol.': [530, 839, 1012, 1564, 2943, 4221], '1994;': [531, 1013, 2944], '266:': [532, 1014], 'H2568-H2572PubMed': [533, 1015], '4Zulueta': [536, 1018], 'J.J.,': [537, 1019], 'Yu,': [538, 1020, 1325], 'F.-S.': [539, 1021], 'Thannickal': [540, 1022], 'V.J.': [541, 1023, 1328], 'Hassoun': [542, 1024], 'Respir.': [546, 1028], 'Cell': [547, 1029, 1841, 1926, 2320, 2595], 'Mol.': [548, 1030, 2332, 3921], 'Biol.': [549, 780, 854, 916, 1031, 1145, 1657, 1992, 2107, 2619, 3616, 3871, 3899], '1995;': [550, 1032], '12:': [551, 1033], '41-49Crossref': [552, 1034], '(141)': [555, 1037], '5Bayraktutan': [558, 1040], 'U.': [559, 700, 776, 778, 846, 908, 1041, 1141, 1143, 1649, 3867, 3869], 'Draper': [560, 701, 1042], 'N.': [561, 581, 702, 1043, 1063, 1246, 2181, 3571], 'Lang': [562, 703, 1044], 'D.': [563, 704, 1045, 2063, 2154, 2928], 'Shah': [564, 705, 849, 911, 1046, 1652, 3918], 'A.M.': [565, 706, 850, 912, 1047, 1653, 3917, 3919], 'Cardiovasc.': [566, 707, 1048], '38:': [569, 710, 1051], '256-262Crossref': [570, 711, 1052], '(162)': [572, 713, 1054, 1337], '6De': [575, 1057], 'Keulenaer': [576, 1058, 1241], 'G.W.': [577, 1059, 1242], 'Chappell': [578, 1060, 1243], 'D.C.': [579, 1061, 1244], 'Ishizaka': [580, 1062, 1245], 'Nerem': [582, 1064, 1247], 'Alexander': [584, 1066, 1249], 'R.W.': [585, 1067, 1250], 'Griendling': [586, 1068, 1251], 'K.K.': [587, 1069, 1252], '1998;': [590, 620, 737, 1072, 1102, 1255, 1285, 1799, 3901, 4222], '82:': [591, 1073, 1256], '1094-1101Crossref': [592, 1074, 1257], '(534)': [595, 1077, 1260], '7Al-Mehdi': [598, 1080, 1263], 'A.B.': [599, 617, 716, 734, 1081, 1099, 1264, 1282], 'Zhao': [600, 717, 1082, 1265], 'G.': [601, 718, 1083, 1266, 2330, 4218], 'Dodia': [602, 719, 1084, 1267], 'Tozawa': [604, 721, 1086, 1269], 'K.': [605, 607, 633, 722, 724, 750, 800, 890, 1087, 1089, 1115, 1165, 1270, 1272, 1298, 1795, 1987, 2611], 'Costa': [606, 723, 1088, 1271], 'Muzykantov': [608, 725, 1090, 1273], 'V.': [609, 726, 1091, 1274, 3597, 3893], 'Ross': [610, 727, 1092, 1275], 'Blecha': [612, 729, 1094, 1277], 'F.': [613, 637, 730, 754, 894, 1095, 1119, 1278, 1302, 2094, 2100, 2284, 3607], 'Dinauer': [614, 731, 1096, 1279], 'M.': [615, 635, 732, 752, 770, 892, 1097, 1117, 1135, 1280, 1300, 2143, 3310, 3314, 3334, 3605, 3861], 'Fisher': [616, 733, 1098, 1281], '83:': [621, 738, 1103, 1286], '730-737Crossref': [622, 739, 1104, 1287], '(248)': [625, 742, 1107, 1290], '8Görlach': [628, 745, 1110, 1293], 'A.': [629, 746, 886, 1111, 1294, 1561, 1983, 2039, 2102, 2744, 3330], 'Brandes': [630, 747, 887, 1112, 1295], 'R.P.': [631, 748, 888, 1113, 1296], 'Nguyen': [632, 749, 889, 1114, 1297], 'Amidi': [634, 751, 891, 1116, 1299], 'Dehghani': [636, 753, 893, 1118, 1301], 'Busse': [638, 755, 895, 1120, 1303], 'R.': [639, 756, 896, 1121, 1304, 2057], '2000;': [642, 759, 782, 817, 855, 899, 917, 1124, 1147, 1182, 1307, 1333, 1352, 1658, 1993, 3873], '87:': [643, 760, 900, 1125, 1308, 2194, 3584], '26-32Crossref': [644, 761, 901, 1126, 1309], '(543)': [647, 764, 904, 1129, 1312], 'Several': [650], 'have': [652, 866, 979, 1632], 'suggested': [653, 980], 'at': [655, 690, 952, 990, 1436, 1552, 1902, 1943, 2403, 2419, 2455, 2524, 2807, 3025, 3038, 3060, 3075, 3099, 3127, 3666, 3702, 3728, 3754, 4154, 4168, 4299], 'molecular': [657, 954], 'level,': [658], 'is': [663, 1195, 1366, 1392, 1425, 1539, 1714, 3365], 'analogous': [664], 'phagocyte': [667], 'all': [673, 1694], 'main': [675, 1697], 'components': [676, 1698], 'phagocytic': [679, 2302], '(i.e.': [681, 1952, 2588, 4202], 'Rac1)': [687], 'detectable': [689, 1540], 'both': [691, 1485, 1628], 'mRNA': [692], '(5Bayraktutan': [699], 'Scholar,7Al-Mehdi': [715], '9Sohn': [767, 1132], 'H.-Y.': [768, 1133, 3859], 'Keller': [769, 1134, 3860], 'Gloe': [771, 1136, 3862], 'T.': [772, 802, 804, 808, 812, 1137, 1167, 1169, 1173, 1177, 1330, 1981, 2144, 3863], 'Morawietz': [773, 1138, 3864], 'H.': [774, 1139, 1318, 3865, 3889], 'Rueckschloss': [775, 1140, 3866], 'Pohl': [777, 1142, 3868], 'Chem.': [781, 1146, 2620, 3872, 3900], '275:': [783, 1148, 3874, 4223], '18745-18750Abstract': [784, 1149, 3875], 'Full': [785, 787, 1150, 1152, 2338, 2624, 2626, 3876, 3878, 3904, 3906, 3927], 'Text': [786, 788, 1151, 1153, 2339, 2625, 2627, 3877, 3879, 3905, 3907, 3928], 'PDF': [789, 1154, 2340, 2628, 3880, 3908, 3929], '(108)': [792, 1157, 3883], '10Inoue': [795, 1160], 'I.': [796, 1161, 1989, 3363], 'Goto': [797, 1162], 'S.': [798, 806, 810, 814, 1163, 1171, 1175, 1179, 1793, 1985, 2160, 3599, 3609], 'Mizotani': [799, 1164], 'Awata': [801, 1166], 'Mastunaga': [803, 1168], 'Kawai': [805, 1170], 'Nakajima': [807, 1172], 'Hokari': [809, 1174], 'Komoda': [811, 1176], 'Katayama': [813, 1178], 'Life': [815, 1180], 'Sci.': [816, 1181], '67:': [818, 1183], '863-876Crossref': [819, 1184], '(313)': [822, 1187], '11Jones': [825], 'S.A.': [826, 1347], "O'Donnell": [827], 'V.B.': [828], 'Wood': [829], 'J.D.': [830], 'Broughton': [831], 'J.P.': [832], 'Hughes': [833], 'E.J.': [834], 'Jones': [835], 'O.T.G.': [836], '1996;': [840], '271:': [841], 'H1626-H1634PubMed': [842], '12Bayraktutan': [845, 907], 'Blayney': [847, 909, 1650], 'L.': [848, 910, 1341, 1651], 'Arterioscler.': [851, 913, 1654], 'Thromb.': [852, 914, 1655], 'Vasc.': [853, 915, 1656], '20:': [856, 918, 1659], '1093-1911Crossref': [857, 919, 1660], '(209)': [859, 921, 1662], 'Furthermore,': [862, 1593], 'we': [863, 1625, 1669, 3938], 'others': [865], 'shown': [867, 3360], 'cell': [871, 999, 1530, 1548, 1756, 1887, 1906, 3418, 3504, 3547, 3550, 3712, 3726, 3839, 4052, 4107, 4230], 'p22phox': [872, 1430, 1611, 2293, 2859], 'cDNA': [875], 'sequences': [876, 884], 'highly': [878], 'homologous': [880], 'published': [882], '(8Görlach': [885], 'porcine': [927], 'bovine': [932, 1776, 2427, 2449], 'human': [936, 1760, 1893, 2279, 2301, 2877], 'N-ω-nitro-l-arginine': [941, 4074], 'ester': [943, 4076], 'tetramethylrhodamine': [944], 'isothiocyanate': [945, 2537, 2563, 2590], 'phosphate-buffered': [946], 'Despite': [948], 'this': [949, 3729], 'apparent': [950], 'similarity': [951], 'between': [956, 1380, 4184], 'oxidase,': [962], 'latter': [964], 'number': [967, 3241], 'striking': [969], 'terms': [972], 'its': [974], 'activity.': [975, 1496], 'First,': [976], 'several': [977], 'occurs': [988], 'continuously': [989], 'stimulation': [1000], 'extrinsic': [1002], 'agonists': [1003], '(3Mohazzab-H': [1004], 'In': [1190, 1482, 1606, 1665, 4049], 'contrast,': [1191], 'inactive': [1196], 'quiescent': [1198], 'cells,': [1199, 1624, 2304], 'continuous': [1202], '“basal”': [1203], 'observed': [1205], 'no': [1210], 'obvious': [1211, 1390], 'correlate': [1213], 'neutrophils': [1215, 1969, 2280], '(13Babior': [1216, 1447], 'B.M.': [1217, 1448, 2189, 2924, 3579], 'Blood.': [1218, 1449, 2064], '93:': [1220, 1451], '1464-1476Crossref': [1221, 1452], 'Second,': [1225], 'generated': [1232], 'appears': [1236], '(6De': [1240], '14Li': [1315], 'A.E.': [1316], 'Ito': [1317], 'Rovira': [1319], 'I.I.': [1320], 'Kim': [1321], 'K.-S.': [1322], 'Takeda': [1323], 'K.,': [1324], 'Z.-Y.': [1326], 'Ferrans': [1327], 'Finkel': [1329], '304-310Crossref': [1335], '15Moldovan': [1340], 'Moldovan': [1342], 'N.I.': [1343], 'Sohn': [1344], 'R.H.': [1345, 2922], 'Parikh': [1346], 'Goldschmidt-Clermont': [1348], 'P.J.': [1349], '86:': [1353], '549-557Crossref': [1354], '(158)': [1357], 'Scholar),': [1359], 'whereas': [1360, 3393], 'O2⨪': [1362, 4023, 4043], 'generation': [1363], 'during': [1364], 'phagocytosis': [1365], 'thought': [1367], 'occur': [1369], 'extracellular': [1372], '(phagosomal)': [1373], 'compartment.': [1374], 'underlining': [1377], 'However,': [1388, 1571], 'an': [1389, 4070], 'possibility': [1391], 'structural': [1395], 'assembly': [1396], 'different': [1408, 3228], 'reported': [1411], 'for': [1412, 1494, 1975, 2292, 2316, 2400, 2416, 2452, 2474, 2534, 2561, 2665, 2695, 2748, 2766, 2804, 2846, 2854, 2891, 2906, 2916, 3028, 3042, 3063, 3072, 3096, 3124, 3196, 3218, 3292, 3325, 3345, 3488, 3531, 3705, 3718, 3733, 3758, 3795, 3834, 4157, 4194, 4243], 'neutrophils.': [1413], 'comprises': [1418], 'plasma': [1420, 1519, 1645, 1679, 2865, 3238, 3253, 3490, 3533], 'membrane-bound': [1421, 1520], 'cytochrome': [1422, 1473, 1486, 1521, 3740, 3851, 4103], 'b558': [1423, 1487, 1522], '(which': [1424], 'heterodimer': [1427], 'one': [1429, 1432, 4057], 'subunit)': [1434], 'least': [1437], 'four': [1438, 2825], 'cytosolic': [1439, 1465, 1490], 'subunits,': [1440], 'namely': [1441], 'p40phox,': [1444, 2075], 'Rac1': [1446, 2079], 'During': [1456], 'activation': [1458], 'response': [1460], 'various': [1462], 'agonists,': [1463], 'translocate': [1467], 'associate': [1470], 'b558,': [1474], 'process': [1476], 'activation.': [1481], 'cell-free': [1483], 'assays,': [1484, 4106], 'required': [1493], 'Based': [1497], 'upon': [1498], 'above': [1500, 1640], 'information,': [1501], 'assumed': [1505], 'but': [1506], 'not': [1507, 1575, 1596, 1954], 'proven': [1508], 'should': [1514, 1601], 'also': [1515], 'comprise': [1516, 1590], 'other': [1525, 2318, 3084], 'units': [1526], 'cytosol.': [1531], 'Accordingly,': [1532], '(or': [1535], '“NADPH': [1536], 'activity”)': [1538], 'crude': [1542], 'preparations': [1544], 'particulate': [1547], 'fractions': [1549, 2920, 3140, 3210, 3411, 3558, 3749, 3841, 3953, 4237], 'spun': [1550], 'down': [1551, 4288], '29,000': [1553, 3100], '(16Smith': [1556], 'K.R.': [1557], 'Klei': [1558], 'L.R.': [1559], 'Barchowsky': [1560], '2001;': [1565, 3924], '280:': [1566], 'L442-L449Crossref': [1567], 'data': [1573], 'do': [1574, 1595], 'provide': [1576], 'direct': [1577], 'evidence': [1578], 'regarding': [1579, 1642], 'precise': [1581], 'complexes': [1586], 'or': [1587, 2461, 2487, 2494, 3850, 4035, 4088, 4146, 4187], 'complexes.': [1592], 'they': [1594, 1947], 'explain': [1597], 'why': [1598], '“constitutive”': [1599], 'exist': [1602], 'recent': [1608], 'study': [1609], 'where': [1610, 1709], 'assessed': [1616], 'confocal': [1618, 1677], 'immunofluorescence': [1619], 'rat': [1622], 'appeared': [1630], 'localization,': [1636], 'contrary': [1637], 'speculations': [1641], '(12Bayraktutan': [1648], 'study,': [1668], 'range': [1672], 'complementary': [1674], 'methods': [1675, 1838, 3306, 4210], 'including': [1676], 'microscopy,': [1678], 'biotinylation,': [1682, 2870], 'co-immunoprecipitation': [1686], 'investigate': [1688], 'cultured': [1704, 1856, 2350], 'O2⨪-generating': [1712], 'located.': [1715], 'Culture': [1742, 1842, 1927, 1963], 'media,': [1743], 'fetal': [1744, 1868, 2411], 'calf': [1745, 1869, 2412], 'serum': [1746, 2413, 2428, 2450], '(FCS),': [1747], 'glutamine,': [1748], 'antibiotics': [1750], 'purchased': [1752, 2207], 'Invitrogen.': [1754], 'growth': [1757, 1762, 1888, 1895], 'supplement,': [1758], 'recombinant': [1759, 2074, 2121], 'epidermal': [1761, 1894], 'factor,': [1763, 1920], 'gelatin': [1765, 2357], 'Sigma.': [1768, 2242], 'Porcine': [1769], '(PIEC)': [1774], '(BAEC)': [1780], 'kindly': [1782, 2090, 2139], 'provided': [1783, 2091, 2140], "Fabre's": [1786], 'research': [1787], 'group': [1788], "(King's": [1789], 'College': [1790, 2097], 'London)': [1791, 2098], '(17Yun': [1792], 'Gustafsson': [1794], 'Fabre': [1796], 'J.W.': [1797], 'Transplantation.': [1798], '66:': [1800, 3618], '103-111Crossref': [1801], '(26)': [1804], 'BAEC': [1807], 'PIEC': [1809, 2634, 3629, 4240], 'maintained': [1811], 'RPMI': [1813], '1640': [1814], '10%': [1816, 2254, 2390], 'FCS,': [1817], '2': [1818, 2749, 2805, 3647], 'mml-glutamine,': [1819], '100': [1820, 1824, 2727, 3026, 3174, 3703, 4078, 4111], 'units/ml': [1821], 'penicillin,': [1822], 'μg/ml': [1825, 2728, 2733, 4275, 4279, 4283], 'streptomycin.': [1826], 'Human': [1827, 1998], '(HUVEC)': [1832], 'prepared': [1834, 2323], 'according': [1835, 2011, 3266, 3303], 'established': [1837], '(18Piper': [1839, 1924], 'H.M.': [1840, 1925], 'Techniques': [1843, 1928], 'Heart': [1845, 1930], 'Vessel': [1847, 1932], 'Research.': [1848, 1933], 'Spinger-Verlag,': [1849, 1934], 'Berlin1990:': [1850, 1935], '178-204Crossref': [1851, 1936], 'HUVEC': [1854, 1899], '0.1%': [1858, 2426, 2448, 2785, 4270], '(w/v)': [1859], 'gelatin-coated': [1860], 'flasks': [1861], 'Medium': [1863], '199': [1864], 'supplemented': [1865], '20%': [1867, 2410], 'serum,': [1870], 'heparin': [1871], 'IU/ml),': [1873], 'hydrocortisone': [1874], '(1': [1875, 2987, 3672], 'μg/ml),': [1876, 1882, 1891], 'l-glutamine': [1877], '(2': [1878, 2880, 2993, 2997, 3678, 3681], 'mm),': [1879, 2988, 2991, 3662, 3673, 3676, 4038], 'streptomycin': [1880], '(50': [1881, 1884, 1890, 4094], 'penicillin': [1883], 'units/ml),': [1885], 'supplement': [1889], 'factor': [1896], '(10': [1897, 3664, 4037, 4150], 'ng/ml).': [1898], 'passages': [1903], '2–4.': [1904], 'identity': [1907], 'their': [1911, 2023], 'characteristic': [1912], 'cobblestone': [1913], 'appearance,': [1914], 'positive': [1915, 2290, 2314], 'expression': [1916], 'von': [1918], 'Willebrand': [1919], 'Dil-Ac-LDL': [1922], 'uptake': [1923], 'All': [1939, 3155], 'stage': [1945, 3730], 'when': [1946], 'had': [1948, 2637], 'just': [1949, 2638, 4003], 'achieved': [1950], 'confluence': [1951, 2640], 'proliferating).': [1955], 'HL-60': [1956, 2872], 'American': [1961], 'Type': [1962], 'Collection.': [1964], 'They': [1965], 'differentiated': [1967, 2871], 'incubation': [1971], '1.3%': [1973], 'Me2SO': [1974], '7': [1976], 'days': [1977], '(19Hua': [1978], 'Hasebe': [1980], 'Someya': [1982], 'Nakamura': [1984], 'Sugimoto': [1986], 'Nagaoka': [1988], 'Leukocyte': [1991, 2106, 3615], '68:': [1994], '216-224PubMed': [1995], 'polymorphonuclear': [1999, 2878], 'leukocytes': [2000, 2879], 'isolated': [2002, 2876], 'peripheral': [2004], 'blood': [2005], 'using': [2006, 2515, 3166, 3184, 3260, 3348, 3821, 3844, 4209], 'Percoll': [2008], 'gradient': [2009], '(AmershamBiosciences)': [2010], "manufacturer's": [2014, 3269], 'instructions.': [2015], 'Antibodies': [2016], 'directed': [2017], 'against': [2018, 2073, 2081, 2120], 'sources': [2024], 'follows.': [2027], 'An': [2028], 'anti-p22phox': [2029], 'monoclonal': [2030, 2204, 2225, 2238], 'antibody': [2031, 2239, 2378, 2471, 2478, 2504], '(mAb449)': [2032], 'kind': [2035], 'gift': [2036, 2282], 'Dr.': [2038, 2093, 2142], 'Verhoeven': [2040], '(Central': [2041], 'Laboratory': [2042], 'Blood': [2044], 'Transfusion,': [2045], 'Amsterdam,': [2046], 'Netherlands)': [2048], '(20Verhoeven': [2049], 'A.J.': [2050, 2150, 2179, 3569], 'Bolscher': [2051], 'B.G.J.M.': [2052], 'Meerhof': [2053], 'L.J.': [2054], 'van': [2055], 'Zwieten': [2056], 'Keijer': [2058], 'Weening': [2060], 'R.S.': [2061], 'Roos': [2062], '1987;': [2065], '73:': [2066], '1686-1694Crossref': [2067], 'Rabbit': [2070], 'polyclonal': [2071, 2118, 2221], 'antibodies': [2072, 2119, 2205, 2226, 2440, 4291], '30-amino': [2083], 'acid': [2084, 2132], 'C-terminal': [2085, 2133], 'fragment': [2086, 2134], 'gp91phox(Pep37)': [2088], 'Wientjes': [2095], '(University': [2096], '(21Wientjes': [2099], 'Segal': [2101], 'Hartwig': [2103], '61:': [2109], '303-312Crossref': [2110], '(46)': [2113], 'Separate': [2116], 'rabbit': [2117, 2216, 2493, 4303], '(R360)': [2123], 'p67phox': [2125], '(R1469),': [2126], 'p22phoxholoprotein': [2127], '(R3179),': [2128], '12-amino': [2131], '(R2085)': [2137], 'Quinn': [2145, 2155, 2182, 3572], '(Montana': [2146], 'State': [2147], 'University)': [2148], '(22Jesaitis': [2149], 'Buescher': [2151], 'E.S.': [2152], 'Harrison': [2153], 'M.T.': [2156, 2183, 3573], 'Parkos': [2157], 'C.A.': [2158], 'Livesey': [2159], 'Linner': [2161], '1990;': [2166], '821-835Crossref': [2168], '(104)': [2171], '23Woodman': [2174], 'R.C.': [2175, 3565], 'Ruedi': [2176, 3566], 'J.M.': [2177, 2926, 3567], 'Jesaitis': [2178, 3568], 'Okamura': [2180, 3570], 'Smith': [2184, 3574], 'Curnutte': [2186, 3576], 'J.T.': [2187, 3577], 'Babior': [2188, 3578], '1991;': [2193, 3583], '1345-1351Crossref': [2195, 3585], '(123)': [2198, 3588], 'Anti-p47phox': [2201], 'anti-p67phox': [2203], 'Transduction': [2209], 'Laboratories.': [2210], 'goat': [2212], 'anti-CD31': [2213], '(PECAM-1)': [2214], 'anti-extracellular': [2217], 'signal-regulated': [2218], 'kinase': [2219], '1/2': [2220], 'anti-VE-cadherin': [2224], 'Santa': [2229], 'Cruz': [2230], 'Biotechnology,': [2231], 'Inc.': [2232], '(Santa': [2233], 'Cruz,': [2234], 'CA).': [2235], 'anti-α-tubulin': [2237], 'For': [2243, 2375, 3935, 4102], 'immunoblotting,': [2244], 'equal': [2245], 'amounts': [2246], '(25': [2247], 'μg)': [2248, 3193], 'separated': [2252, 3751], 'on': [2253, 2668, 2698, 2764, 2863, 2911, 3031, 3708, 3716, 4171], 'polyacrylamide': [2255], 'gels': [2256], 'transferred': [2258], 'polyvinylidene': [2260], 'difluoride': [2261], 'membranes.': [2262], 'Membranes': [2263], 'blocked': [2265, 2408, 2686], '5%': [2267], 'nonfat': [2268], 'milk,': [2269], 'PBS,': [2270, 2366, 2659, 2957], '0.2%': [2271], 'Tween': [2272], '20.': [2273], 'Membrane': [2274, 3453], 'extracted': [2276, 2763, 3715, 4238], 'activated': [2278], '(a': [2281], 'Wientjes)': [2285], 'control': [2291, 2315, 2507], 'expression.': [2296], 'extract': [2299, 4232], 'U937': [2303], 'after': [2305], 'phorbol': [2306, 2886], '12-myristate': [2307, 2887], '13-acetate': [2308, 2888], 'subunits.': [2319], 'samples': [2321, 3828, 4247], 'described': [2325, 2608, 2794, 2905, 3562, 3856, 4211], 'previously': [2326, 2609, 3563, 3857, 4212], '(24Li': [2327], 'J.-M.': [2328, 3915, 4214], 'Brooks': [2329, 4217], 'Cell.': [2333, 3922], 'Cardiol.': [2334, 3923], '29:': [2336], '2213-2224Abstract': [2337], '(58)': [2343], 'Briefly,': [2346, 3951], 'onto': [2351, 3987], 'four-chamber': [2352], 'slides': [2353], 'precoated': [2354], '1%': [2356, 2392, 2754, 3979], 'until': [2358], 'nearly': [2359], 'confluent.': [2360], 'Cells': [2361, 2422, 2703, 2745, 2965, 2999, 3640, 3687], 'washed': [2363, 2424, 2646, 2705, 2824, 2953, 3163, 3631, 3779], 'twice': [2364, 2647, 2706, 2954, 3632], 'permeabilized,': [2367], 'fixed': [2369, 2385], 'methanol/acetone': [2371], '(50%': [2372], 'each,': [2373], 'v/v).': [2374], 'staining': [2376], 'α-tubulin': [2380], '(Fig.': [2381], '8),': [2382], '3.7%': [2387], 'paraformaldehyde': [2388], 'plus': [2389, 3669], 'Me2SO,': [2391], 'glucose,': [2393], '0.02%': [2395], 'Triton': [2396, 2755, 3553, 3685, 3745, 3781, 3812, 4234], 'X-100': [2397, 2756], 'PBS': [2399, 2415, 2446, 2650, 2692, 2708, 2833, 3635], '20': [2401, 2666, 2719, 2767, 3719, 4018], 'min': [2402, 2418, 2454, 2667, 2697, 2848, 3044, 3074, 3098, 3126], '37': [2404, 4155], '°C.': [2405, 2809, 4301], 'Slides': [2406], '30': [2417, 2453, 2475, 2892, 4158], 'room': [2420, 2456], 'temperature.': [2421, 2457], 'albumin/PBS': [2429], 'three': [2430, 3475, 3518], 'times': [2431, 2826], 'gentle': [2433], 'shaking': [2434], 'then': [2436, 2895, 3070, 3806], 'incubated': [2437, 2473, 2797, 4153], 'primary': [2439, 2503, 3081], 'diluted': [2441, 2772, 3955, 4113, 4258], '(1:50': [2442], '1:250)': [2444], 'albumin': [2451], 'Biotin-conjugated': [2458], 'anti-rabbit': [2459], 'IgG': [2460, 2463, 2496], 'anti-mouse': [2462], '(1:500': [2464], 'dilution)': [2465], 'secondary': [2470], 'min.': [2476, 2768, 3065, 3720, 3760, 4019, 4159], 'Specific': [2477], 'binding': [2479], 'detected': [2481], 'fluorescein': [2483, 2562, 2589], 'isothiocyanate-labeled': [2484], '(green': [2485], 'fluorescence)': [2486, 2490], 'TRITC-labeled': [2488], '(red': [2489], 'extravidin.': [2491], 'Normal': [2492, 4302], 'mouse': [2495], 'μg/ml)': [2498], 'instead': [2501], 'negative': [2506], 'each': [2509, 3190, 3249, 3352], 'case.': [2510], 'performed': [2514, 2587, 2606, 3560, 4099, 4208], 'Bio-Rad': [2517, 3186, 3823], '1024': [2518], 'system.': [2519], 'Optical': [2520], 'sections': [2521], 'taken': [2523], '0.5-μm': [2525], 'intervals,': [2526], 'images': [2528], 'captured': [2530], 'stored': [2532], 'digitally': [2533], 'analysis.': [2535], 'Fluorescein': [2536], 'excited': [2539, 2550], '488-nm': [2542], 'argon': [2543], 'ion': [2544], 'laser': [2545, 2556], 'line,': [2546], 'TRITC': [2548, 2565], '543-nm': [2553], 'green': [2554], 'helium/neon': [2555], 'line.': [2557], 'emission': [2559, 2579, 4007], 'filters': [2560, 2580], 'HQ': [2567, 2570], '515/30': [2568], '580/40,': [2571], 'respectively.': [2572, 3297, 3496, 3539], 'To': [2573, 2856, 3220], 'avoid': [2574], 'bleed-through,': [2575], 'while': [2576], 'allowing': [2577], 'optimal': [2578], 'used,': [2583], 'sequential': [2584], 'acquisitions': [2585], 'first': [2591], 'followed': [2592, 3008, 3696], 'TRITC).': [2594], 'surface': [2596, 2897], 'streptavidin-agarose': [2600, 2803], 'purification': [2601], 'biotinylated': [2603, 2852], 'proteins': [2604, 2770, 2814, 2853], '(25Tanaka': [2610], 'Chazenbalk': [2612], 'G.D.': [2613], 'McLachlan': [2614], 'S.M.': [2615], 'Rapoport': [2616], 'B.': [2617], '274:': [2622], '33979-33984Abstract': [2623], '(50)': [2631], 'monolayers': [2635], 'reached': [2639], '60-mm': [2642], 'culture': [2643, 4128], 'dishes': [2644], 'ice-cold': [2649, 2715, 2956, 3634, 3650], '(pH': [2651, 2693, 2722, 2780, 3981, 4265], '8.0),': [2652], 'EZ-link™': [2654], 'sulfo-NHS-LC-biotin': [2655], '(0.5': [2656], 'mg/ml': [2657], 'pH': [2660, 2982, 3667], '8.0;': [2661], 'Pierce)': [2662], 'added': [2664, 2758, 3999, 4142], 'ice.': [2669, 3032, 3709], 'solution': [2671, 2761], 'removed,': [2673], 'cross-linking': [2676], 'procedure': [2677], 'repeated.': [2679], 'aspiration,': [2681], 'remaining': [2683], 'biotin': [2684], '50': [2688, 4274], 'mm': [2689, 2720, 2725, 2778, 2783, 2977, 2980, 3962, 3965, 3968, 3971, 3974], 'NH4Cl': [2690], '8.0)': [2694], '10': [2696], 'ice': [2699, 2765, 3717], 'occasional': [2701], 'agitation.': [2702], 'scratched': [2710, 2959], 'into': [2711, 2759, 2817, 2960, 3552, 4000], '1': [2712, 2732, 3973, 4278, 4282], 'ml': [2713, 3648, 3810], 'buffer': [2716, 2743, 2775, 2828, 2839, 2975, 3161, 3215, 3652, 3782, 3833, 3959, 4261], 'containing': [2718, 2812, 2984, 3653, 3960, 4262], 'Hepes': [2721, 2779], '7.2),': [2723, 2781], '150': [2724], 'NaCl,': [2726, 2784, 3963, 4269], 'phenylmethylsulfonyl': [2729, 2985, 3670, 4276], 'fluoride,': [2730, 4277], 'leupeptin.': [2734, 4284], 'pelleted,': [2738], 'rinsed,': [2739], 'resuspended': [2741, 2969, 3158, 3645, 3807], 'sonicated': [2747], '15': [2751, 3029, 3064, 3073, 3097, 3706, 3759], 's,': [2752], 'Solubilized': [2769], '1:1': [2773], 'B': [2776, 2829], '(20': [2777, 2970, 2976, 3012, 3655], '300': [2782], 'SDS,': [2786], '0.5%': [2787], 'Nonidet': [2788, 4271], 'P-40,': [2789], 'protease': [2791], 'inhibitors': [2792], 'above)': [2795], '25': [2799, 3976], 'μl': [2800, 3175], 'prewashed': [2802], 'h': [2806], '4': [2808, 4300], 'supernatant': [2811, 3068, 3090, 3118, 3144, 3790], 'nonbiotinylated': [2813], 'removed': [2816, 3766], 'new': [2819, 3510, 3769], 'tube.': [2820, 2964], 'beads': [2822, 4296], 'once': [2831, 3164], 'before': [2834, 3171, 4004], 'resuspending': [2835, 3172], 'Laemmli': [2837], 'sample': [2838, 3275], '0.6%': [2841], 'β-mercaptoethanol.': [2842], 'Samples': [2843], 'boiled': [2845, 3830], '5': [2847, 3043, 3964], 'release': [2850], 'bound,': [2851], 'immunodetection.': [2855], 'ensure': [2857], 'amenable': [2868], 'freshly': [2875], '106/ml)': [2882, 2972], 'stimulated': [2884], '(100': [2889, 3192, 3985, 3991, 4067, 4086, 4139], 'ng/ml': [2890], 'min),': [2893], 'underwent': [2896], 'same': [2902], 'way': [2903], 'PIEC.': [2907], 'Differential': [2908], 'centrifugation': [2909, 3059, 3169, 3753], 'based': [2910], 'standard': [2912], 'protocols': [2913], 'isolation': [2917], '(26Hinton': [2921], 'Mullock': [2923], 'Graham': [2925], 'Rickwood': [2927], 'Subcellular': [2929], 'Fractionation.': [2930], 'Oxford': [2931], 'University': [2932], 'Press,': [2933], 'Oxford1997:': [2934], '31-69Google': [2935], '27Mohazzab': [2937], '267:': [2945], 'L815-L822PubMed': [2946], 'Confluent': [2949, 3628], '12-ml': [2962], 'Falcon': [2963], 'pelleted': [2967, 3057], 'MOPS-KOH': [2974, 3177], 'MOPS-KOH,': [2978], '250': [2979], 'sucrose,': [2981], '7.4)': [2983], 'fluoride': [2986, 3671], 'EDTA': [2989, 3674], '(0.1': [2990, 3675], 'leupeptin': [2992, 3677], 'μm),': [2994, 3679], 'pepstatin': [2996, 3680], 'μm).': [2998, 4095], 'disrupted': [3001, 3689], 'quick': [3003, 3691], 'freezing': [3004, 3692], 'liquid': [3006, 3694], 'nitrogen': [3007, 3695], 'two': [3010, 3021, 3698], 'cycles': [3011, 3022, 3699], 's': [3013, 3030, 3707], 'each)': [3014], 'homogenization': [3016, 3160], '(Polytron': [3017], 'PT': [3018], '2100)': [3019], 'sonication': [3024, 3701], 'W': [3027, 3704], 'homogenate': [3034, 3713, 3727], 'quickly': [3036], 'centrifuged': [3037, 3071, 3095, 3123], '200': [3039, 4132], 'remove': [3046], 'any': [3047], 'possible': [3048], 'unbroken': [3049], 'nuclei-enriched': [3052], 'fraction': [3053, 3093, 3121, 3147, 3191, 3804], '(N': [3054], 'fraction)': [3055, 3764, 3777], '×g': [3062], 'resulting': [3067], '10,800': [3076], 'obtain': [3080, 3104], 'mitochondria': [3082, 3293], 'large': [3085, 3435], 'organelles': [3086], '(C': [3087], 'fraction).': [3088, 3116, 3142, 3154], 'C': [3092, 3391], 'pellet': [3106, 3134, 3773], 'submitochrondrial': [3108], 'particles,': [3109], 'smaller': [3110], 'organelles,': [3111], 'some': [3113, 3626, 4050], 'microsomes': [3114], '(D': [3115], 'D': [3120], '60': [3125], '100,000': [3128], 'sediment': [3132], 'microsomes,': [3136], 'microperoxisomes,': [3137], '(E': [3141], 'E': [3146, 3374], 'includes': [3148], 'soluble': [3150, 3787, 3816], 'cytoplasmic': [3151], '(S': [3153], 'pellets': [3156], 'again': [3165], 'original': [3168], 'conditions': [3170], 'buffer.': [3178], 'concentration': [3181, 3818, 4110], 'determined': [3183, 3259, 3820], 'kit.': [3187, 3824], 'Proteins': [3188, 4285], 'analyzed': [3195], 'chemiluminescence': [3202, 3849, 3936], '(see': [3203], 'below).': [3204], 'rest': [3206], 'dissolved': [3212], 'SDS': [3214, 3832], 'immunoblotting.': [3219, 3835], 'evaluate': [3221], 'degree': [3223], '“purity”': [3225], 'fractions,': [3230], 'especially': [3231], 'regard': [3233], 'partitioning': [3235], 'membrane,': [3239, 3491, 3534], 'marker': [3243, 3290, 3406, 3486, 3529], 'activities': [3245, 3299], 'assayed': [3247], 'As': [3251], 'marker,': [3255], '5′-nucleotidase': [3256, 3368], 'Sigma': [3262], 'Diagnostic': [3263], 'Kit': [3264], '(Sigma)': [3265, 4297], 'instructions': [3270], 'minor': [3272], 'modifications': [3273], 'volumes.': [3276], 'Fumarase': [3277], '(EC': [3279, 3285], '4.2.1.2)': [3280], 'lactate': [3282, 3346, 3394, 3481, 3524], 'dehydrogenase': [3283, 3347, 3395, 3482, 3525], '1.1.1.27)': [3286], 'enzymes': [3291, 3487, 3530], 'cytosol,': [3296, 3495, 3538], 'Their': [3298], 'measured': [3301, 3843, 4025, 4164], 'spectrophotometrically': [3302], 'Stitt': [3308], '(28Stitt': [3309], 'Bergmeyer': [3311, 3331], 'Graßl': [3313, 3333], 'Methods': [3315, 3335], 'Enzymatic': [3317, 3337], 'Analysis.': [3318, 3338], 'Verlag': [3319, 3339], 'Chemie,': [3320, 3340], 'Weinheim,': [3321, 3341], 'Germany1984:': [3322], '359-362Google': [3323], 'Scholar)': [3324, 3344, 3624], 'fumarase': [3326, 3385], 'Vassault': [3328], '(29Vassault': [3329], 'Germany1983:': [3342], '119-139Google': [3343], '25–50-μg': [3349], 'aliquots': [3350], 'assays': [3358], 'Table': [3362], 'It': [3364], 'evident': [3366, 3379], 'enriched': [3371, 3388, 3399], 'fraction,': [3375, 3392], 'little': [3377], 'N': [3382], 'Mitochondrial': [3384], 'significantly': [3398], 'S': [3402], 'fraction.Table': [3403], 'IDistribution': [3404], 'PIECSubcellular': [3413], 'fractionsEnzyme': [3414], 'activity5′-NucleotidaseFumaraseLactate': [3415], 'dehydrogenasenmol/min/mg': [3416], 'proteinWhole': [3417], 'homogenate28.13': [3419], '±': [3420, 3422, 3424, 3427, 3429, 3431, 3437, 3439, 3441, 3447, 3449, 3451, 3456, 3458, 3460, 3464, 3466, 3468, 3472, 3515], '4.7624.50': [3421], '5.2177.24': [3423], '17.15N:': [3425], 'Nuclei-enriched9.08': [3426], '3.689.94': [3428], '0.8322.40': [3430], '14.83C:': [3432], 'Mitochondria': [3433], 'organelles31.80': [3436], '3.3746.26': [3438], '3.71*33.38': [3440], '13.51D:': [3442], 'Submitichondria': [3443], 'small': [3445], 'organelles20.62': [3446], '2.1827.58': [3448], '1.9338.3': [3450], '14.69E:': [3452], 'microsomes50.66': [3455], '5.38*9.28': [3457], '1.5367.82': [3459], '15.77S:': [3461], 'Cytoplasmic': [3462], 'protein17.82': [3463], '4.808.28': [3465], '1.25206.80': [3467], '16.02*Results': [3469], 'mean': [3471, 3514, 4013], 'S.D.': [3473, 3516], 'independent': [3476, 3519], 'experiments.': [3477, 3520, 4245], '5′-nucleotidase,': [3478, 3521], 'fumase,': [3479, 3522], 'mitochondrial': [3492, 3535, 4091], 'matrix,': [3493, 3536], '*,': [3497, 3540], 'p': [3498, 3541], '<': [3499, 3542], '0.05': [3500, 3543], 'compared': [3501, 3544], 'whole': [3503, 3546, 3711, 3725, 4229], 'homogenate.': [3505, 3548], 'Open': [3506], 'table': [3507], 'tab': [3511], 'Results': [3512], 'Extracting': [3549], 'X-100-soluble': [3554, 3746, 3763], '-insoluble': [3556, 3748], '(cytoskeleton)': [3557], '(23Woodman': [3564], '30El': [3591], 'Benna': [3592], 'Dang': [3594], 'Andrieu': [3596], 'Vergnaud': [3598], 'Dewas': [3600], 'Cachia': [3602], 'O.': [3603], 'Fay': [3604], 'Morel': [3606], 'Chollet-Martin': [3608], 'Hakim': [3610], 'Gougerot-Pocidalo': [3612], 'M.-A.': [3613], '1014-1020Crossref': [3619], '(44)': [3622], 'modifications.': [3627], 'detached': [3637], 'scratching.': [3639], '(4': [3641], '107)': [3643], 'extraction': [3651], 'Hepes/Tris': [3654], 'mmeach),': [3656], 'NaCl': [3657], '(0.12': [3658], 'm),': [3659], 'KCl': [3660], 'glucose': [3663, 3980], 'mm)': [3665, 4151], '7.4': [3668], '2%': [3684], 'X-100.': [3686], 'kept': [3732], 'assay.': [3743], '14,000': [3755], 'Supernatant': [3761], '(Triton': [3762, 3774], 'tube,': [3770], 'X-100-insoluble': [3775, 4235], 'cytoskeleton': [3776, 3803], 'eliminate': [3784], 'residual': [3786, 3799], 'element': [3788], '(the': [3789], 'wash': [3792], 'reserved': [3794], 'assay': [3797, 3854], 'activity).': [3801], '0.5': [3809], 'buffer,': [3813], 'Aliquots': [3825], 'either': [3845, 4028], '(9Sohn': [3858], '31Li': [3886], 'Y.': [3887], 'Zhu': [3888], 'Kuppusamy': [3890], 'P.': [3891], 'Roubaud': [3892], 'Zweier': [3894], 'Trush': [3896], 'M.A.': [3897], '273:': [3902], '2015-2023Abstract': [3903], '(480)': [3911], '32Li': [3914], 'Mullen': [3916], '33:': [3925], '1119-1131Abstract': [3926], '(51)': [3932], 'studies,': [3937], '96-well': [3941, 4125], 'microplate': [3942, 4173], 'luminometer': [3943], '(model': [3944], 'Lucy': [3945], '1;': [3946], 'Rosys': [3947], 'Anthos,': [3948], 'Wals,': [3949], 'Austria).': [3950], 'modified': [3957, 4116], 'HEPES': [3958], '140': [3961], 'KCl,': [3966], '0.8': [3967], 'MgCl2,': [3969], '1.8': [3970], 'CaCl2,': [3972], 'Na2HPO4,': [3975], 'mmHEPES,': [3977], '7)': [3982], 'distributed': [3984, 4123], 'μg/well)': [3986, 4112], 'microplate.': [3989], 'dark-adapted': [3994], 'well': [4002], 'reading.': [4005], 'Light': [4006], 'recorded': [4009], 'arbitrary': [4014], 'light': [4015], 'units/min': [4016], 'over': [4017], 'specificity': [4021], 'thus': [4024], 'adding': [4030], 'superoxide': [4031], 'dismutase': [4032], '(200': [4033], 'units/ml)': [4034], 'Tiron': [4036, 4149, 4189], 'nonenzymatic': [4040], 'scavenger': [4041], 'quench': [4045], 'O2⨪-dependent': [4047], 'chemiluminescence.': [4048], 'experiments,': [4051], 'homogenates': [4053], 'preincubated': [4055], 'following': [4060], 'agents:': [4061], 'flavoprotein': [4064], 'inhibitor,': [4065, 4073, 4084, 4092], 'diphenyleneiodonium': [4066], 'μm);': [4068, 4079, 4087], 'NO': [4071], 'synthase': [4072], '(l-NAME,': [4077], '(c)': [4080], 'xanthine': [4082], 'oxypurinol': [4085], '(d)': [4089], 'rotenone': [4093], 'Each': [4096], 'experiment': [4097], 'triplicate.': [4101], '(final': [4109, 4130], "Dulbecco's": [4115], "Eagle's": [4117], 'medium': [4118], 'without': [4119, 4188], 'phenol': [4120], 'red': [4121], 'flat': [4126], 'bottom': [4127], 'plates': [4129], 'volume': [4131, 4253], 'μl/well).': [4133], 'Cytochrome': [4134, 4160], 'c(500': [4135], 'presence': [4145], '°C': [4156], 'reading': [4166], 'absorbance': [4167, 4185], '550': [4169], 'nm': [4170], 'reader.': [4174], 'nmol/mg': [4177], 'calculated': [4180], 'difference': [4183], 'extinction': [4192], 'coefficient': [4193], 'change': [4195], 'ferricytochrome': [4197], 'ferrocytochrome': [4200], '21.0': [4203], 'mmol·liter−1·cm−1).': [4204], '(33Li': [4213], 'Poolman': [4215], 'R.A.': [4216], 'H814-H822Crossref': [4224], 'Protein': [4246], '(250': [4248], 'μg': [4249], 'final': [4252], '750': [4255], 'μl)': [4256], 'immunoprecipitation': [4260], '0.05m': [4263], 'Tris-HCl': [4264], '7.4),': [4266], '0.25': [4267], 'm': [4268], 'P-40': [4272], '(v/v),': [4273], 'aprotinin,': [4280], 'immunoprecipitated': [4287], 'appropriate': [4290], 'coupled': [4292], 'G-agarose': [4295], 'overnight': [4298], 'IgG-coup': [4304]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2092759252', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 4}, {'year': 2020, 'cited_by_count': 6}, {'year': 2019, 'cited_by_count': 7}, {'year': 2018, 'cited_by_count': 5}, {'year': 2017, 'cited_by_count': 9}, {'year': 2016, 'cited_by_count': 7}, {'year': 2015, 'cited_by_count': 9}, {'year': 2014, 'cited_by_count': 16}, {'year': 2013, 'cited_by_count': 14}, {'year': 2012, 'cited_by_count': 29}], 'updated_date': '2024-12-14T05:39:51.136535', 'created_date': '2016-06-24'}