Publication Information

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3557, 3569, 3572, 3585, 3601, 3604, 3635, 3672, 3681, 3687, 3699, 3712, 3737, 3751, 3809, 3815, 3912, 3915, 3919, 4053, 4082, 4087, 4128, 4141, 4174, 4177, 4183, 4229, 4248, 4296, 4301, 4321, 4334, 4345, 4349, 4364, 4379], 'somatostatin': [3, 71, 97, 115, 134, 154, 212, 280, 306, 324, 343, 363, 446, 450, 494, 632, 702, 799, 801, 825, 843, 858, 876, 975, 1003, 1128, 1925, 1945, 1971, 2226, 2236, 2440, 3214, 3216, 3268, 3594, 3605, 3664, 3935, 4305], 'receptor': [4, 12, 213, 221, 976, 1168, 1326, 1369, 1390, 1414, 1442, 1673, 1714, 1756, 1766, 1926], 'sst2,': [5, 57, 142, 214, 266, 351, 3264, 3306, 3925, 4283], 'a': [6, 19, 35, 74, 99, 136, 215, 228, 244, 283, 308, 345, 420, 456, 804, 808, 956, 1097, 1117, 1202, 1217, 1467, 1592, 1608, 1883, 1947, 2240, 2269, 2510, 2973, 3033, 3321, 3353, 3538, 3668, 3856, 3897, 3901, 3947, 4075, 4169, 4222, 4244, 4311, 4317, 4383], 'member': [7, 216], 'Gi': [10, 219], 'protein-coupled': [11, 220, 506, 1542, 1923], 'family,': [13, 222], 'results': [14, 223, 1196, 1824, 1930, 3892, 4164], 'in': [15, 24, 58, 73, 93, 149, 169, 224, 233, 267, 282, 302, 358, 378, 960, 978, 997, 1102, 1229, 1312, 1536, 1596, 1616, 1647, 1757, 1795, 1813, 1819, 1825, 1916, 1956, 2088, 2107, 2123, 2265, 2344, 2397, 2402, 2423, 2435, 2453, 2460, 2483, 2487, 2608, 2618, 2621, 2655, 2724, 2753, 2785, 2803, 2819, 2862, 2922, 2936, 3043, 3177, 3209, 3257, 3313, 3364, 3387, 3404, 3421, 3441, 3491, 3499, 3510, 3600, 3661, 3667, 3692, 3717, 3744, 3750, 3770, 3775, 3849, 3955, 3995, 4061, 4086, 4127, 4140, 4166, 4173, 4209, 4216, 4300, 4354, 4369, 4389], 'stimulation': [17, 226, 806, 3787, 3913, 3930], 'protein-tyrosine': [20, 37, 229, 246, 810, 818, 851, 1611], 'phosphatase': [21, 38, 187, 230, 247, 396, 811, 1959, 4346], 'activity': [22, 113, 231, 322, 1010, 3174, 3220, 3743, 3767, 3779, 3790, 3933, 4060, 4149, 4332, 4347], 'involved': [23, 148, 232, 357, 1228, 3954, 4085], 'sst2-mediated': [26, 235, 1205], 'growth': [27, 236, 645, 710, 720, 884, 965, 1105, 1316, 1324, 1598, 1811, 1887, 1905, 2448, 2499], 'inhibitory': [28, 237, 423, 4302], 'signal.': [29, 238, 968], 'Here,': [30, 239], 'we': [31, 240, 695, 1114, 3307, 3477, 3926, 4309, 4373], 'report': [32, 241], 'that': [33, 144, 193, 242, 353, 402, 425, 452, 701, 955, 1096, 1116, 1164, 1198, 1220, 1823, 1894, 1901, 1944, 1952, 3260, 3435, 3479, 3486, 3644, 3844, 3853, 3894, 3929, 3946, 4067, 4123, 4277, 4285, 4377, 4387], 'SHP-1,': [34, 163, 243, 372, 1124], 'cytoplasmic': [36, 245], 'containing': [39, 248, 2346, 2404, 2455, 2489, 2627, 2730, 2844, 3046, 3512], 'two': [40, 249, 1222, 4380], 'Src': [41, 250, 1223], 'homology': [42, 251, 1224], '2': [43, 252, 1225, 1679], 'domains': [44, 253, 1227], 'constitutively': [45, 254], 'associated': [46, 188, 255, 397, 3623, 3910], 'with': [47, 56, 189, 256, 265, 398, 1087, 1126, 1232, 1314, 1364, 1438, 1670, 1712, 1803, 1940, 2098, 2171, 2219, 2268, 2492, 2509, 2714, 2778, 2837, 2906, 2931, 2978, 3069, 3267, 3305, 3395, 3483, 3497, 3517, 3525, 3547, 3589, 3616, 3624, 3631, 3639, 3677, 3784, 3830, 3835, 3911, 3942, 4043, 4101, 4114, 4187, 4201, 4386, 4402], 'sst2': [48, 64, 69, 80, 161, 172, 190, 257, 273, 278, 289, 370, 381, 399, 974, 996, 1086, 1167, 1924, 1941, 2121, 2279, 3213, 3312, 3319, 3370, 3398, 3439, 3454, 3464, 3484, 3498, 3560, 3590, 3625, 3648, 3693, 3716, 3998, 4092, 4188, 4210, 4273, 4368], 'as': [49, 184, 258, 393, 718, 1123, 1322, 1749, 1907, 2230, 2257, 2280, 2353, 2517, 2567, 2668, 2794, 2986, 3071, 3134, 3320, 3329, 3352, 3871, 3873, 4117, 4119, 4392], 'evidence': [50, 259, 1932, 4294], 'by': [51, 70, 82, 114, 118, 128, 207, 260, 279, 291, 323, 327, 337, 416, 1108, 1475, 1602, 1753, 1899, 1965, 2183, 2211, 2217, 2506, 2561, 2616, 3022, 3029, 3114, 3327, 3378, 3537, 3593, 3629, 3722, 3934, 3938, 4074, 4099, 4153, 4158, 4192, 4235, 4243, 4315, 4394], 'coprecipitation': [52, 261], 'SHP-1': [54, 78, 86, 88, 112, 177, 183, 263, 287, 295, 297, 321, 386, 392, 1199, 1209, 1310, 1357, 1472, 1532, 1595, 1606, 1669, 1711, 1744, 1794, 1821, 1881, 1895, 1915, 1939, 1951, 2055, 2102, 2104, 2166, 2249, 2251, 3265, 3303, 3310, 3351, 3391, 3401, 3408, 3443, 3480, 3496, 3588, 3622, 3675, 3691, 3718, 3742, 3766, 3771, 3778, 3789, 3845, 3862, 3868, 4059, 4062, 4071, 4090, 4212, 4275, 4281, 4299, 4314, 4350, 4365], 'protein': [55, 264, 469, 2911, 2984, 3322, 3354, 3392, 3412, 3952, 4084], 'Chinese': [59, 268, 821, 854, 981], 'hamster': [60, 269, 822, 855, 982], 'ovary': [61, 270, 983], 'cells': [62, 95, 159, 170, 271, 304, 368, 379, 985, 1084, 1163, 1618, 1649, 2082, 2338, 2394, 2413, 2450, 2477, 2508, 2834, 3197, 3211, 3259, 3367, 3375, 3503, 3597, 3730, 3825, 3851, 3923, 3941, 4042, 4096, 4195, 4371, 4391, 4399], 'coexpressing': [63, 160, 171, 272, 369, 380], 'and': [65, 96, 101, 130, 133, 162, 164, 173, 191, 274, 305, 310, 339, 342, 371, 373, 382, 400, 435, 438, 468, 508, 633, 642, 696, 703, 880, 980, 1004, 1436, 1636, 1645, 1680, 1808, 1935, 1942, 1961, 1970, 1982, 2007, 2022, 2037, 2092, 2112, 2329, 2339, 2349, 2407, 2420, 2429, 2458, 2559, 2614, 2650, 2782, 2806, 2817, 2868, 2884, 2934, 2976, 3027, 3057, 3124, 3195, 3311, 3350, 3409, 3485, 3515, 3541, 3561, 3614, 3634, 3765, 3799, 3833, 3852, 3858, 3884, 3900, 3914, 4011, 4017, 4091, 4108, 4135, 4205, 4211, 4274, 4367, 4372], 'SHP-1.': [66, 275, 3384, 3562, 3821], 'resulted': [72, 281, 3403, 3666], 'rapid': [75, 100, 137, 284, 309, 346, 805, 3857, 4245], 'dissociation': [76, 138, 285, 347, 3903, 4271, 4279], 'from': [79, 141, 288, 350, 1160, 1992, 1999, 2013, 2027, 2041, 2047, 2307, 2320, 2333, 3188, 3373, 4094, 4272, 4282], 'accompanied': [81, 290], 'an': [83, 198, 292, 407, 2409, 2471], 'increase': [84, 293, 3670, 3899, 4224], 'activity.': [87, 296], 'was': [89, 116, 125, 167, 298, 325, 334, 376, 1927, 1990, 1997, 2046, 2070, 2169, 2209, 2500, 2557, 2638, 2653, 2751, 2775, 2788, 2792, 2875, 3067, 3112, 3175, 3198, 3393, 3591, 3626, 3720, 3768, 3780, 3791, 3846, 3869, 3879, 3909, 3936, 3953, 4072, 4112, 4125, 4207, 4241, 4258, 4337], 'phosphorylated': [90, 299, 882, 3068, 3848], 'on': [91, 104, 300, 313, 713, 1008, 2663, 3741, 3814, 4058, 4306], 'tyrosine': [92, 105, 186, 301, 314, 395, 714, 1318, 1643, 1958, 3818, 3847], 'control': [94, 303, 3888], 'induced': [98, 135, 307, 344, 1107, 3855, 3896, 4221], 'transient': [102, 311, 3669, 3859, 3898, 3916, 4223], 'dephosphorylation': [103, 312, 3860, 3866, 3917], 'residues': [106, 315, 2275], 'enzyme.': [109, 318, 3920, 4335], 'Stimulation': [110, 319], 'abolished': [117, 326, 4052, 4344], 'pertussis': [119, 328, 3943, 3948, 4006, 4044, 4076], 'toxin': [120, 329, 3944, 3949, 4045], 'pretreatment': [121, 330, 3939], 'cells.': [123, 332, 3315, 3501, 3746, 4356], 'Giα3': [124, 140, 145, 333, 349, 354, 2330, 4010, 4111, 4124, 4172, 4186, 4206, 4232, 4257, 4270], 'specifically': [126, 335], 'immunoprecipitated': [127, 336, 2961, 3453, 3523, 3651, 3676, 4113, 4152, 4233], 'anti-sst2': [129, 338, 2261, 3527, 3548, 3617, 3640, 3678, 4115, 4236], 'anti-SHP-1': [131, 340, 2303, 3530, 3550, 3632, 3831, 3839, 4120, 4238], 'antibodies,': [132, 341, 2912, 4121], 'suggesting': [143, 352, 954, 1095, 4066, 4122, 4284], 'may': [146, 196, 355, 405, 958, 1099, 1200, 1953], 'be': [147, 197, 356, 406, 1100, 1201, 1897, 1954, 4003, 4151, 4190, 4289], 'sst2·SHP-1': [151, 360, 3487, 3701, 3906, 4088, 4129, 4142, 4178], 'complexes.': [152, 361, 4130, 4179], 'Finally,': [153, 362], 'inhibited': [155, 364], 'proliferation': [157, 366, 786, 1684], 'this': [165, 194, 374, 403, 1910, 3466, 3956], 'effect': [166, 375, 708, 1001, 1007, 3738, 3810, 3957, 4055, 4303], 'suppressed': [168, 377, 3937], 'catalytic': [175, 384, 4323, 4331], 'inactive': [176, 385, 4313], '(C453S': [178, 387], 'mutant).': [179, 388], 'Our': [180, 389, 1929], 'data': [181, 390], 'identify': [182, 391, 4081], 'demonstrate': [192, 401, 1943], 'enzyme': [195, 404], 'initial': [199, 408], 'key': [200, 409], 'transducer': [201, 410], 'antimitogenic': [204, 413], 'signaling': [205, 414, 1207, 1234, 1721, 1767], 'mediated': [206, 415, 448, 4073], 'sst2.': [208, 417, 1111, 1966, 3410, 3473], 'Somatostatin': [418], 'is': [419, 1216, 1533, 1801, 1882, 1946, 4328], 'widely': [421], 'distributed': [422], 'hormone': [424], 'exhibits': [426], 'various': [427, 1805, 3609, 3758, 4199], 'biological': [428, 443], 'effects,': [429], 'including': [430, 462], 'neurotransmission,': [431], 'inhibition': [432, 639, 783, 963], 'exocrine': [434], 'endocrine': [436], 'secretions,': [437], 'cell': [439, 644, 785, 1440, 1764, 1904, 2392, 2447, 2636, 4307], 'proliferation.': [440], 'The': [441, 629, 1791, 2049, 2207, 2301, 2773, 2873, 2925, 3063, 3110, 3619, 3786, 3841, 3865, 4266], 'diverse': [442, 512], 'effects': [444, 1094], 'are': [447, 453, 787, 3489, 3566], 'through': [449, 2967], 'receptors': [451, 495, 507, 716, 886, 1129, 1320, 1543, 1613, 3269], 'coupled': [454, 4004], 'to': [455, 501, 511, 637, 781, 798, 988, 1362, 1538, 1640, 1760, 1810, 2085, 2272, 2917, 2972, 3126, 3543, 3568, 3612, 3642, 3803, 3828, 4002, 4005, 4015, 4339], 'variety': [457, 1609], 'signal': [459, 513, 1106, 1685, 1917], 'transduction': [460, 514, 1918], 'pathways': [461, 515], 'adenylate': [463], 'cyclase,': [464], 'ionic': [465], 'conductance': [466], 'channels,': [467], 'phosphatases': [470], '(1Yamada': [471], 'T.': [472, 474, 554, 913, 1056, 1373, 1479, 1518, 1651, 1835, 2290, 2365, 2579, 2680, 3230, 3339, 4026], 'Chiba': [473], 'Handb.': [475], 'Physiol.': [476, 485], '1989;': [477, 683, 737, 768, 902], '2:': [478], '431-453Google': [479], 'Scholar,': [480, 542, 568, 583, 606, 667, 744, 909, 924, 1046, 1252, 1271, 1292, 1494, 1516, 1563, 1855], '2Lewin': [481], 'M.J.': [482, 756], 'Annu.': [483], 'Rev.': [484, 659], '1992;': [486, 535, 560, 579, 599, 917, 946, 1264, 1285, 1302, 1508, 2158], '54:': [487], '455-468Crossref': [488], 'PubMed': [489, 538, 566, 602, 624, 663, 686, 740, 771, 905, 920, 949, 1042, 1077, 1155, 1248, 1267, 1288, 1305, 1352, 1386, 1408, 1431, 1461, 1492, 1514, 1527, 1559, 1583, 1631, 1664, 1703, 1739, 1786, 1851, 1870, 2161, 2202, 2296, 2386, 2551, 2600, 2701, 3015, 3105, 3168, 3251, 3295, 3345, 3989, 4036], 'Google': [490, 541, 567, 582, 605, 627, 666, 689, 743, 774, 908, 923, 952, 1045, 1080, 1158, 1191, 1251, 1270, 1291, 1308, 1355, 1387, 1411, 1434, 1464, 1493, 1515, 1530, 1562, 1586, 1634, 1665, 1706, 1742, 1789, 1854, 1873, 2164, 2205, 2299, 2389, 2554, 2603, 2704, 3016, 3108, 3171, 3254, 3298, 3348, 3992, 4037], 'Scholar).': [491, 628, 690, 775, 1081, 1192, 1309, 1356, 1465, 1531, 1587, 1666, 1707, 1743, 1790, 1874, 2165, 2206, 2300, 2390, 2555, 2604, 2705, 3017, 3109, 3172, 3255, 3299, 3993, 4038], 'Recently': [492], 'five': [493], 'have': [496, 698, 1590], 'been': [497, 647, 793, 1360, 1638, 1746, 4000], 'cloned.': [498], 'They': [499], 'belong': [500], 'family': [503], 'G': [505, 1541, 1922, 3951, 4008, 4078, 4083], 'can': [509, 4150, 4189, 4288], 'couple': [510], '(3Yamada': [516, 2139], 'Y.': [517, 587, 2140], 'Post': [518, 2141], 'S.R.': [519, 2142], 'Wang': [520, 2143], 'K.': [521, 544, 2144, 2286, 3335, 4022], 'Tager': [522, 2145], 'H.S.': [523, 2146], 'Bell': [524, 555, 1025, 1059, 2147, 2287, 2368, 2534, 2582, 2683, 3088, 3151, 3233, 3336, 3972, 4023], 'G.I.': [525, 556, 1026, 1060, 2148, 2288, 2369, 2535, 2583, 2684, 3089, 3152, 3234, 3337, 3973, 4024], 'Seino': [526, 2149], 'S.': [527, 533, 546, 597, 681, 735, 758, 900, 1037, 1072, 1283, 1328, 1420, 1728, 1861, 2150, 2156, 2381, 2546, 2595, 2696, 3100, 3163, 3246, 3984], 'Proc.': [528, 592, 676, 730, 895, 1067, 1278, 2151, 2376, 2590, 2691, 3241], 'Natl.': [529, 593, 677, 731, 896, 1033, 1068, 1279, 2152, 2377, 2542, 2591, 2692, 3096, 3159, 3242, 3980], 'Acad.': [530, 594, 678, 732, 897, 1034, 1069, 1280, 2153, 2378, 2543, 2592, 2693, 3097, 3160, 3243, 3981], 'Sci.': [531, 595, 620, 679, 733, 898, 1035, 1070, 1281, 2154, 2379, 2544, 2593, 2694, 3098, 3161, 3244, 3982], 'U.': [532, 596, 680, 734, 899, 1036, 1071, 1282, 1330, 1392, 1394, 1687, 1689, 2155, 2380, 2545, 2594, 2695, 3099, 3162, 3245, 3983], 'A.': [534, 598, 682, 736, 901, 1038, 1073, 1284, 1334, 1338, 1549, 1626, 2157, 2382, 2547, 2596, 2697, 2924, 3101, 3164, 3247, 3985], '89:': [536, 600, 1286, 2159], '251-255Crossref': [537, 2160], 'Scopus': [539, 603, 625, 664, 687, 741, 772, 906, 921, 950, 1043, 1078, 1156, 1249, 1268, 1289, 1306, 1353, 1409, 1432, 1462, 1528, 1560, 1584, 1632, 1704, 1740, 1787, 1852, 1871, 2162, 2203, 2297, 2387, 2552, 2601, 2702, 3106, 3169, 3252, 3296, 3346, 3990], '(722)': [540, 2163], '4Yasuda': [543], 'Rens-Domiano': [545], 'Breder': [547], 'C.D.': [548], 'Law': [549], 'S.F.': [550, 4020], 'Saper': [551], 'C.B.': [552, 618], 'Reisine': [553, 1055, 2289, 2364, 2578, 2679, 3229, 3338, 4025], 'J.': [557, 589, 944, 1151, 1273, 1341, 1505, 1555, 1571, 1572, 1624, 2291, 3291, 3340, 4027], 'Biol.': [558, 1263, 1301, 1342, 1382, 1427, 1488, 1506, 1523, 1573, 1660, 1735, 4028], 'Chem.': [559, 1343, 1507, 1574, 4029], '267:': [561, 1509], '20422-20428Abstract': [562], 'Full': [563, 1347, 1349, 1405, 1511, 1578, 1580, 1700, 1848, 4033], 'Text': [564, 1348, 1350, 1406, 1512, 1579, 1581, 1701, 1849, 4034], 'PDF': [565, 1351, 1407, 1513, 1582, 1702, 1850, 4035], "5O'Carroll": [569], 'A.M.': [570, 750, 1058, 2367, 2581, 2682, 3232], 'Lolait': [571], 'S.J.': [572], 'Konig': [573], 'M.': [574, 591, 673, 727, 892, 932, 1131, 1141, 1175, 1416, 1724, 2058, 3000, 3002, 3271, 3281], 'Mahan': [575], 'L.C.': [576, 1396, 1691], 'Mol.': [577, 1186, 1261, 1299, 1380, 1425, 1486, 1521, 1658, 1733], 'Pharmacol.': [578, 1187], '42:': [580], '939-946PubMed': [581], '6Bruno': [584], 'J.F.': [585], 'Xu': [586], 'Song': [588], 'Berelowitz': [590], '11151-11155Crossref': [601], '(314)': [604], '7Patel': [607], 'Y.C.': [608], 'Greenwood': [609], 'M.T.': [610], 'Panetta': [611], 'R.': [612, 1332, 1622], 'Demchyshyn': [613], 'L.': [614, 762, 930, 1012, 1048, 1143, 1239, 1862, 1984, 2059, 2357, 2521, 2571, 2672, 3075, 3138, 3222, 3283, 3959], 'Niznik': [615], 'H.': [616, 1020, 1139, 1553, 2529, 3004, 3083, 3146, 3279, 3967], 'Srikant': [617], 'Life': [619, 2042], '1995;': [621, 1074, 1344, 1402, 1428, 1458, 1556, 1575, 1697, 1736, 1783, 2383, 2597, 2698, 3012, 3248], '57:': [622], '1249-1265Crossref': [623], '(337)': [626], 'ability': [630], 'its': [634, 1005, 1230, 2340], 'stable': [635], 'analogues': [636, 704, 802, 3217], 'promote': [638], 'normal': [641], 'tumor': [643, 693], 'has': [646, 792, 1358, 1637, 1745, 3999], 'known': [648], 'for': [649, 1204, 2225, 2245, 2416, 2432, 2480, 2611, 2644, 2721, 2767, 2828, 2878, 2891, 2900, 2943, 2951, 3128, 3380, 3507, 3608, 3731, 3757, 4046, 4171, 4198, 4330], 'many': [650], 'years': [651], '(8Lamberts': [652], 'S.W.': [653], 'Krenning': [654], 'E.P.': [655], 'Reubi': [656], 'J.C.': [657, 1456, 1781], 'Endocr.': [658], '1991;': [660, 1245], '12:': [661, 1265, 1303], '450-482Crossref': [662], '(844)': [665], '9Liebow': [668], 'C.': [669, 671, 723, 725, 752, 764, 888, 890, 928, 942, 1028, 1066, 1137, 1149, 1171, 1185, 1977, 2375, 2537, 2589, 2690, 2990, 3010, 3091, 3154, 3240, 3277, 3289, 3975], 'Reilly': [670, 724, 889], 'Serrano': [672, 726, 891], 'Schally': [674, 728, 893, 1029, 1061, 2370, 2538, 2584, 2685, 3092, 3155, 3235, 3976], 'A.V.': [675, 729, 894, 1030, 1062, 2371, 2539, 2585, 2686, 3093, 3156, 3236, 3977], '86:': [684, 738, 903], '2003-2007Crossref': [685, 739, 904], '(308)': [688, 742, 907], 'In': [691, 1112, 1909, 3921, 4131, 4146], 'pancreatic': [692, 1161, 3258], 'cells,': [694, 3997], 'others': [697], 'previously': [699, 2282, 2355, 2569, 2670, 2988, 3136, 3206, 3330, 3927], 'shown': [700, 794, 1361, 1639, 3386, 3774], 'antagonize': [705], 'mitogenic': [707, 967, 1600], 'factors': [711, 1477, 1812, 1900], 'acting': [712], 'kinase': [715, 1319, 1612, 1678, 1719], 'such': [717, 1321, 1906], 'epidermal': [719, 883, 1323], 'factor': [721, 885, 1317, 1325, 1599, 1888], '(9Liebow': [722, 887], '10Viguerie': [745], 'N.': [746, 766, 940, 1014, 1064, 1147, 1177, 1183, 1565, 2373, 2523, 2587, 2688, 3008, 3077, 3140, 3238, 3287, 3961], 'Tahiri': [747], 'J.N.': [748, 1298, 1379, 1485, 1520, 1657, 1837], 'Ayral': [749], 'Cambillau': [751, 927, 1136, 3276], 'Scemama': [753], 'J.L.': [754, 1296], 'Bastie': [755], 'Knuhtsen': [757], 'Estève': [759, 933, 1015, 1049, 1132, 1178, 2358, 2524, 2572, 2673, 2997, 3078, 3141, 3223, 3272, 3962], 'J.P.': [760, 934, 1016, 1050, 1133, 1179, 2359, 2525, 2573, 2674, 2998, 3079, 3142, 3224, 3273, 3963], 'Pradayrol': [761, 1142, 3282], 'Susini': [763, 941, 1065, 1148, 1184, 2374, 2588, 2689, 3009, 3239, 3288], 'Vaysse': [765, 939, 1063, 1146, 1182, 2372, 2586, 2687, 3007, 3237, 3286], 'Endocrinology.': [767, 3011], '124:': [769], '1017-1025Crossref': [770], '(105)': [773], 'Although': [776], 'molecular': [778], 'events': [779, 4287], 'leading': [780], 'still': [788], 'poorly': [789], 'understood,': [790], 'it': [791], 'that,': [795, 3208], 'after': [796, 2408, 3685, 3705, 3760, 3793, 3876, 4260], 'binding': [797, 2227, 2237, 2750, 2780, 2791], 'receptors,': [800, 1367, 3215], 'cause': [803], 'membrane': [809, 1127, 2011, 2710], '(PTPase)': [812], '1The': [813], 'abbreviations': [814, 847], 'used': [815, 848, 1752], 'are:': [816, 849], 'PTPase,': [817, 850], 'phosphatase;': [819, 852], 'CHO,': [820, 853], 'ovary;': [823, 856], 'sst,': [824, 857], 'receptor;': [826, 859], 'MEM,': [827, 860], 'modified': [828, 861, 4191], "Eagle's": [829, 862], 'medium;': [830, 863], 'FCS,': [831, 864, 2406], 'fetal': [832, 865, 2033], 'calf': [833, 866, 2034], 'serum;': [834, 867], 'PAGE,': [835, 868], 'polyacrylamide': [836, 869], 'gel': [837, 870], 'electrophoresis;': [838, 871], 'CHAPS,': [839, 872], '3-[(3-cholamidopropyl)dimethylammonio]': [840, 873], '-1-propanesulfonate;': [841, 874], 'SMS,': [842, 875, 2442, 3607], 'analogue': [844, 877], 'SMS': [845, 878, 1967, 3657, 3709, 3727, 3740, 3756, 3797, 3812, 3854, 3877, 3895, 4057, 4204, 4219, 4264], '201-995.1The': [846], '201-995.activity': [879], 'dephosphorylate': [881], '11Pan': [910], 'M.G.': [911], 'Florio': [912], 'Stork': [914], 'P.J.': [915], 'Science.': [916, 1457, 1627, 1782], '256:': [918], '1215-1217Crossref': [919], '(195)': [922], '12Colas': [925], 'B.': [926], 'Buscail': [929], 'Zeggari': [931, 1174], 'Lautre': [935], 'V.': [936, 1054, 2363, 2577, 2678, 3228], 'Thomas': [937, 1259, 1840], 'F.': [938, 1547], 'Eur.': [943], 'Biochem.': [945, 1150, 3290], '207:': [947], '1017-1024Crossref': [948], '(81)': [951], 'Scholar)': [953, 1159, 1635, 3349], 'PTPase': [957, 1009, 1089, 1098, 1118, 1219, 2949, 2952, 3044, 3173, 3219, 3932, 4148], 'participate': [959], 'somatostatin-induced': [962, 1957], 'factor-mediated': [966], 'Recently,': [969], 'expression': [971, 2074], 'subtype': [977, 1169], 'NIH3T3': [979], '(CHO)': [984], 'led': [986], 'us': [987], 'demonstration': [990], 'direct': [993, 4293], 'involvement': [994], 'both': [998, 1093], 'antiproliferative': [1000, 1962], 'stimulatory': [1006, 4054], '(13Buscail': [1011, 2520, 3074, 3137, 3958], 'Delesque': [1013, 1176, 2522, 3076, 3139, 3960], 'Saint': [1017, 1051, 1180, 2360, 2526, 2574, 2675, 2995, 3080, 3143, 3225, 3964], 'L.N.': [1018, 1052, 1181, 2361, 2527, 2575, 2676, 2996, 3081, 3144, 3226, 3965], 'Prats': [1019, 2528, 3003, 3082, 3145, 3966], 'Clerc': [1021, 2530, 3084, 3147, 3968], 'P.': [1022, 1024, 1243, 2531, 2533, 2994, 3085, 3087, 3148, 3150, 3969, 3971], 'Robberecht': [1023, 2532, 3086, 3149, 3970], 'Liebow': [1027, 2536, 3090, 3153, 3974], 'et': [1031, 2189, 2540, 3094, 3157, 3978], 'al.Proc.': [1032, 2541, 3095, 3158, 3979], '1994;': [1039, 1152, 1188, 2293, 2548, 3102, 3165, 3292, 3342, 3986], '91:': [1040, 2549, 3103, 3166, 3987], '2315-2319Crossref': [1041, 2550, 3104, 3167, 3988], '(319)': [1044, 2553, 3107, 3170, 3991], '14Buscail': [1047], 'Bertrand': [1053, 2362, 2576, 2677, 3227], "O'Carroll": [1057, 2366, 2580, 2681, 3231], '92:': [1075, 2384, 2598, 2699, 3249], '1580-1584Crossref': [1076, 2385, 2599, 2700, 3250], '(297)': [1079, 2388, 2602, 2703, 3253], 'Incubation': [1082], 'expressing': [1085, 2235, 3212, 3924], 'inhibitor,': [1090, 2855], 'vanadate,': [1091], 'prevented': [1092], 'implicated': [1101, 1748], 'negative': [1104, 1797, 1884], 'activation': [1109, 1539, 1960, 4069], 'addition,': [1113], 'demonstrated': [1115, 4001, 4393], '70': [1120], 'kDa,': [1121, 3357], 'identified': [1122, 4208], 'copurified': [1125, 3266], '(15Zeggari': [1130, 3270], 'Rauly': [1134, 1172, 2991, 3274], 'I.': [1135, 1173, 1450, 1775, 2128, 2992, 3275], 'Mazarguil': [1138, 3278], 'Dufresne': [1140, 3280], 'Chayvialle': [1144, 3284], 'J.A.': [1145, 3285], '303:': [1153, 3293], '441-448Crossref': [1154, 3294], '(43)': [1157, 3297], 'acinar': [1162], 'highly': [1165, 3261], 'expressed': [1166, 3176, 3262, 3318, 4353, 4378], '(16Vidal': [1170], '46:': [1189], '97-104PubMed': [1190], 'Taken': [1193], 'together,': [1194], 'these': [1195, 1470, 1476, 3359, 3475, 3891, 3996, 4163, 4286], 'suggest': [1197], 'candidate': [1203], 'early': [1206, 3872], 'events.': [1208], '(also': [1210], 'named': [1211], 'SHPTP-1,': [1212], 'SHP,': [1213], 'or': [1214, 2103, 2250, 2486, 2493, 2913, 2945, 2960, 2982, 3529, 3549, 3552, 3823, 3838, 4237], 'HCP)': [1215], 'non-transmembrane': [1218], 'contains': [1221], '(SH2)': [1226], 'association': [1231, 1709, 1937, 4184], 'multiple': [1233], 'molecules': [1235, 3649], '(17Shen': [1236], 'S.H.': [1237], 'Bastien': [1238], 'Posner': [1240], 'B.I.': [1241], 'Chretien': [1242], 'Nature.': [1244], '352:': [1246], '736-739Crossref': [1247], '(336)': [1250], '18Matthews': [1253], 'R.J.': [1254, 1839], 'Bowne': [1255], 'D.B.': [1256], 'Flores': [1257], 'E.': [1258, 1336, 3006], 'M.L.': [1260, 1841], 'Cell.': [1262, 1300, 1381, 1401, 1426, 1487, 1522, 1659, 1696, 1734, 1844], '2396-2405Crossref': [1266], '(325)': [1269], '19Plutzky': [1272], 'Neel': [1274, 1397, 1423, 1692, 1731], 'B.G.': [1275, 1398, 1424, 1693, 1732], 'Rosenberg': [1276], 'R.D.': [1277], '1123-1127Crossref': [1287], '(286)': [1290], '20Yi': [1293], 'T.L.': [1294], 'Cleveland': [1295], 'Ihle': [1297, 1378, 1484, 1519, 1656, 1836], '836-846Crossref': [1304], '(306)': [1307], 'associates': [1311, 3482], 'vivo': [1313], 'activated': [1315, 1365, 1898], '(21Tomic': [1327], 'Greiser': [1329], 'Lammers': [1331, 1621], 'Kharitonenkov': [1333], 'Imyanitov': [1335], 'Ullrich': [1337, 1625], 'Bohmer': [1339], 'F.D.': [1340], '270:': [1345, 1576], '21277-21284Abstract': [1346], '(135)': [1354], 'also': [1359, 1437, 1534, 1747], 'associate': [1363], 'cytokine': [1366], 'interleukin-3': [1368], 'β': [1370], 'chain': [1371], '(22Yi': [1372, 1478, 1650], 'Mui': [1374, 1480, 1652], 'A.L.': [1375, 1481, 1653], 'Krystal': [1376, 1482, 1654], 'G.': [1377, 1452, 1483, 1655, 1777, 2127], '1993;': [1383, 1489, 1524, 1628, 1661, 1845, 1867, 4030], '13:': [1384, 1490, 1525, 1662], '7577-7586Crossref': [1385, 1491, 1663], 'Scholar),': [1388, 1412, 1435], 'erythropoietin': [1389, 1672], '(23Klingmuller': [1391, 1686], 'Lorenz': [1393, 1688], 'Cantley': [1395, 1690], 'Lodish': [1399, 1694], 'H.F.': [1400, 1695], '80:': [1403, 1698], '729-738Abstract': [1404, 1699], '(836)': [1410, 1705], 'interferon-α/β': [1413, 1713], '(24David': [1415, 1723], 'Chen': [1417, 1725], 'H.E.': [1418, 1726], 'Goelz': [1419, 1727], 'Larner': [1421, 1729], 'A.C.': [1422, 1730], '15:': [1429, 1737], '7050-7058Crossref': [1430, 1738], '(316)': [1433, 1741], 'B': [1439, 1758, 1763], 'FcγRIIB': [1441], "(25D'Ambrosio": [1443, 1768], 'D.': [1444, 1769], 'Hippen': [1445, 1770], 'K.L.': [1446, 1498, 1771], 'Minskoff': [1447, 1772], 'S.A.': [1448, 1773], 'Mellman': [1449, 1774], 'Pani': [1451, 1776], 'Siminovitch': [1453, 1778, 1858], 'K.A.': [1454, 1779, 1859], 'Cambier': [1455, 1780], '268:': [1459, 1784, 4031], '293-297Crossref': [1460, 1785], '(507)': [1463, 1788], 'As': [1466, 3385, 3659, 3773, 4214], 'result': [1468], 'interactions,': [1471], 'becomes': [1473], 'tyrosine-phosphorylated': [1474, 1535], '26Yeung': [1495], 'Y.G.': [1496], 'Berg': [1497], 'Pixley': [1499], 'F.J.': [1500], 'Angeletti': [1501], 'R.H.': [1502], 'Stanley': [1503], 'E.R.': [1504], '23447-23450Abstract': [1510], '27Yi': [1517], '3350-3358Crossref': [1526], '(234)': [1529], 'response': [1537], '(28Li': [1544], 'R.Y.': [1545], 'Gaits': [1546], 'Ragab': [1548, 1550], 'T.J.': [1551], 'Chap': [1552], 'EMBO': [1554], '14:': [1557], '2519-2526Crossref': [1558], '(63)': [1561], '29Rivard': [1564], 'McKenzie': [1566], 'F.R.': [1567], 'Brondello': [1568], 'J.M.': [1569], 'Pouyssegur': [1570], '11017-11024Abstract': [1577], '(93)': [1585], 'Recent': [1588], 'studies': [1589, 2660], 'suggested': [1591], 'role': [1593, 1792, 1879, 1913, 4170, 4297], 'terminating': [1597], 'signals': [1601, 1963], 'dephosphorylating': [1603], 'critical': [1604], 'molecules.': [1605], 'dephosphorylates': [1607], 'when': [1614, 3417], 'coexpressed': [1615, 3309, 4363], '293': [1617], '(30Vogel': [1619], 'W.': [1620], 'Huang': [1623], '259:': [1629], '1611-1614Crossref': [1630], '(488)': [1633], 'down-regulate': [1641], 'interleukin-3-induced': [1642], 'phosphorylation': [1644, 3819], 'mitogenesis': [1646], 'hematopoietic': [1648, 1806], 'Association': [1667], 'causes': [1674], 'inactivation': [1675], 'Janus': [1677, 1718], 'termination': [1681], 'erythropoietin-induced': [1683], 'Similarly,': [1708, 3400, 3711], 'negatively': [1715, 1902], 'regulates': [1716], 'interferon-α/β-induced': [1717], '1/Stat1': [1720], 'pathway': [1722, 1919], 'mediator': [1751], 'FcγRIIB1': [1755], 'lymphocytes': [1759], 'turn': [1761], 'off': [1762], 'antigen': [1765], 'regulation': [1798, 1885], 'hematopoiesis': [1800], 'consistent': [1802], 'abnormalities': [1807], 'hypersensitivity': [1809], 'mice': [1814], 'carrying': [1815], 'lethal': [1817], 'mutation': [1818, 2208, 4319, 4342], 'gene': [1822, 2122], 'motheaten': [1826], 'phenotype': [1827], '(31Shultz': [1828], 'L.D.': [1829], 'Schweitzer': [1830], 'P.A.': [1831], 'Rajan': [1832], 'T.V.': [1833], 'Yi': [1834], 'Matthews': [1838], 'Beier': [1842], 'D.R.': [1843], '73:': [1846], '1445-1454Abstract': [1847], '(685)': [1853], '32Tsui': [1856], 'H.W.': [1857], 'de,': [1860], 'Tsui': [1863], 'F.W.': [1864], 'Nat.': [1865], 'Genet.': [1866], '4:': [1868], '124-129Crossref': [1869], '(512)': [1872], 'If': [1875], 'one': [1876, 1890], 'signaling,': [1889], 'might': [1891], 'therefore': [1892], 'speculate': [1893], 'could': [1896], 'regulate': [1903], 'somatostatin.': [1908, 2759, 2812], 'study,': [1911], 'investigated.': [1928], 'provide': [1931], 'physical': [1934], 'functional': [1936], 'physiological': [1948], 'modulator': [1949], 'required': [1955], 'initiated': [1964, 3113], '201–995': [1968], '(SMS)': [1969], 'were': [1972, 2012, 2026, 2040, 2083, 2093, 2223, 2243, 2263, 2305, 2318, 2332, 2342, 2395, 2414, 2427, 2451, 2478, 2606, 2661, 2712, 2761, 2814, 2835, 2898, 2927, 2965, 3020, 3041, 3361, 3376, 3414, 3419, 3505, 3522, 3535, 3598, 3637, 3650, 3748, 3763, 3826, 4097, 4137, 4196, 4400], 'generous': [1973], 'gifts': [1974], 'Dr.': [1976, 1983], 'Bruns': [1978], '(Sandoz,': [1979], 'Basel,': [1980], 'Switzerland)': [1981], 'Moroder': [1985], '(Munich,': [1986], 'Germany),': [1987], 'respectively.': [1988], '[Tyr11]somatostatin': [1989, 2556], 'purchased': [1991, 1998, 2319], 'Bachem.': [1993], '[γ-33P]ATP': [1994, 3070], '(3,000': [1995], 'Ci/mmol)': [1996], 'Isotopchim': [2000], '(France).': [2001], 'Enhanced': [2002], 'chemiluminescence': [2003], '(ECL)': [2004], 'immunodetection': [2005, 3025], 'system': [2006, 3026], 'Hybond': [2008], 'ECL': [2009, 3024], 'nitrocellulose': [2010, 2974], 'Amersham': [2014], 'Corp.': [2015], 'Poly(Glu,': [2016], 'Tyr),': [2017], 'cholesterol': [2018], 'hemisuccinate,': [2019], 'geneticin': [2020], '(G418),': [2021], 'Sepharose-protein': [2023, 2918], 'A': [2024, 2919, 2933], 'beads': [2025, 2920, 2926], 'Sigma.': [2028], 'Minimal': [2029], 'essential': [2030], 'medium': [2031], '(αMEM),': [2032], 'serum': [2035, 2732, 2915, 3055, 3426, 3554], '(FCS),': [2036], 'Lipofectin': [2038, 2096], 'reagent': [2039, 2097], 'Technologies,': [2043], 'Inc.': [2044], 'CHAPS': [2045, 2867], 'Serva.': [2048], '2.1-kilobase': [2050], 'HindIII/NotI': [2051], 'fragment': [2052, 2118], 'mouse': [2054, 2120, 2278], 'cDNA': [2056], '(Dr.': [2057, 2126], 'Thomas,': [2060], 'Howard': [2061, 2130], 'Hughes': [2062, 2131], 'Medical': [2063, 2132], 'Institute,': [2064, 2133], 'Washington': [2065], 'University,': [2066], 'St.': [2067], 'Louis,': [2068], 'MO)': [2069], 'subcloned': [2071], 'into': [2072, 3459, 4320], 'vector': [2075, 2077, 2111, 2125], 'pcDNAneo': [2076], '(Invitrogen).': [2078], 'CHO': [2079, 2337, 3210, 3314, 3366, 3922, 4370], '(DG44': [2080], 'variant)': [2081], 'grown': [2084, 2607], '50%': [2086], 'confluency': [2087], '60-mm': [2089], 'diameter': [2090], 'dishes': [2091, 2399, 2462], 'cotransfected': [2094], 'using': [2095, 2184, 2228, 2253, 3032, 3200], '1': [2099, 2444, 2495, 2757, 2810, 2848, 3052, 3754, 3882, 4202], 'μg': [2100, 2114, 2708], '(C453S)': [2105, 2167], 'mutant': [2106, 2168, 4351, 4366], 'pcDNA': [2108], 'I': [2109], 'neo': [2110], '3': [2113, 2901, 3732, 4107], '1.2-kilobase': [2116], 'XbaI': [2117], 'pCMV6c': [2124], 'Bell,': [2129], 'University': [2134], 'Chicago,': [2136, 2137], 'IL)': [2138], 'constructed': [2170], 'oligonucleotide': [2173], 'primer': [2174], '5′-GAT': [2175], 'GCC': [2176], 'AGC': [2177], 'GCT': [2178], 'GGA': [2179], 'ATG': [2180], 'CAC': [2181], 'AAT-3′': [2182], 'method': [2186], 'Kunkel': [2188], 'al.': [2190], '(33Kunkel': [2191], 'T.A.': [2192], 'Roberts': [2193], 'J.D.': [2194], 'Zakour': [2195], 'R.A.': [2196], 'Methods': [2197], 'Enzymol.': [2198], '1987;': [2199], '154:': [2200], '367-382Crossref': [2201], '(4540)': [2204], 'confirmed': [2210], 'dideoxynucleotide': [2212], 'sequencing.': [2213], 'Stable': [2214], 'colonies': [2215], 'obtained': [2216, 2306], 'selection': [2218], 'G418': [2220, 2350], '(600': [2221], 'μg/ml)': [2222, 2352], 'screened': [2224, 2244], '[125I-Tyr11]somatostatin': [2229, 2717], 'described': [2231, 2258, 2281, 2354, 2518, 2568, 2669, 2987, 3072, 3135], 'below.': [2232, 2259], 'Cellular': [2233], 'clones': [2234, 3317, 4375], 'sites': [2238], 'at': [2239, 2443, 2463, 2502, 2640, 2647, 2718, 2763, 2770, 2824, 2831, 2881, 2887, 2903, 3131, 3185, 3652, 3881, 4049, 4225, 4382], 'similar': [2241, 4384], 'level': [2242, 3816, 4385], 'presence': [2247, 2437, 2755, 2808, 2864, 3382, 3423, 3602, 3752], '(mutant)': [2252], 'Western': [2254], 'blot': [2255], 'analysis': [2256, 3031], 'Polyclonal': [2260], 'antibodies': [2262, 2304, 2313, 2331, 2985, 3551, 3633, 3641, 3679, 3832, 4102, 4116, 4155, 4239], 'generated': [2264, 4310], 'rabbits': [2266], 'immunized': [2267], 'peptide': [2270], 'corresponding': [2271], 'amino': [2273], 'acid': [2274], '191–206': [2276], '(34Thevéniau': [2283, 3332], 'M.A.': [2284, 3333], 'Yasuda': [2285, 3334, 4021], 'Neurochem.': [2292, 3341], '63:': [2294, 3343], '447-455Crossref': [2295, 3344], '(19)': [2298, 3347], 'monoclonal': [2302], 'Transduction': [2308], 'Laboratories': [2309, 2335], '(Medgene,': [2310], 'France).': [2311, 2325, 3038], 'Monoclonal': [2312], 'raised': [2314], 'against': [2315, 4104], 'phosphotyrosine': [2316], '(PY-20)': [2317], 'Santa': [2321], 'Cruz': [2322], 'Biotechnology': [2323], '(Tebu,': [2324], 'Goα1–2,': [2326], 'Giα1–2,': [2327], 'Giα2,': [2328, 4134], 'Gramsch': [2334], '(Germany).': [2336], 'derivatives': [2341], 'cultured': [2343, 2415, 2421, 2452, 2479, 3506], 'αMEM': [2345, 2403, 2454, 2485, 2488, 3511], '10%': [2347, 2405, 2456, 2490, 3513], 'FCS': [2348, 2457, 2491, 3514], '(200': [2351], '(14Buscail': [2356, 2570, 2671, 3221], 'For': [2391, 2446, 2954], 'treatment,': [2393, 3595, 3878], 'plated': [2396, 2459], '100-mm': [2398], '(106': [2400], 'cells/dish)': [2401], 'overnight': [2410, 2422, 2472], 'attachment': [2411, 2473], 'phase,': [2412], '24': [2417, 2481, 3508], 'h,': [2418], 'washed,': [2419], 'serum-free': [2424, 2484], 'αMEM.': [2425], 'Cells': [2426, 2605, 2813, 3747], 'rinsed': [2428], 'then': [2430, 2928, 3627, 3807], 'incubated': [2431, 2713, 2899, 3599, 3749, 4401], 'indicated': [2433, 2504, 3567], 'times': [2434, 2505, 3610, 4200], 'analogue,': [2441, 3606], 'nm.': [2445], 'assay,': [2449], '35-mm': [2461], '55': [2464], '×': [2465, 2642, 2765, 2826, 2889], '103': [2466], 'cells/ml': [2467], '(2': [2468], 'ml/dish).': [2469], 'After': [2470, 2633, 2822], 'phase': [2474], '(time': [2475], '0),': [2476], 'h': [2482, 2613, 2902, 3509, 4048], 'without': [2494], 'nm': [2496, 3755, 4203], 'SMS.': [2497, 3785], 'Cell': [2498], 'measured': [2501, 3769], 'counting': [2507], 'Coulter': [2511], 'counter': [2512], 'model': [2513], 'ZM': [2514], '(Coulter': [2515], 'Electronics)': [2516], 'elsewhere': [2519, 3073], 'radioiodinated': [2558], 'purified': [2560], 'reverse': [2562], 'phase-high': [2563], 'performance': [2564], 'liquid': [2565, 2619], 'chromatography': [2566], '75-cm2': [2609], 'flasks': [2610], '48': [2612], 'lysed': [2615], 'freezing': [2617], 'nitrogen': [2620], '50': [2622, 2725, 2838, 2938, 3047], 'mm': [2623, 2726, 2745, 2839, 2846, 2849, 2857, 2870, 3048, 3059], 'Tris-HCl': [2624, 2727, 2840, 3049], '(pH': [2625, 2728, 2842, 3050], '7.8)': [2626, 2729], 'soybean': [2628, 2736, 2853], 'trypsin': [2629, 2737, 2854], 'inhibitor': [2630, 2738], '(0.3': [2631, 2739], 'mg/ml).': [2632], 'thawing,': [2634], 'lyzate': [2637], 'centrifuged': [2639, 2762, 2886], '26,000': [2641], 'g': [2643, 2766, 2827, 2890], '30': [2645, 2715, 2879, 3132, 3186, 3683, 3794, 3874, 4226], 'min': [2646, 2723, 2769, 2830, 2880, 3130, 3184, 3707, 3883, 4262], '4': [2648, 2771, 2832, 2882, 2904], '°C,': [2649, 2833], 'pellet': [2652, 2774, 2787], 'resuspended': [2654, 2935, 3042], 'same': [2657], 'buffer.': [2658], 'Binding': [2659], 'performed': [2662, 3199, 3420], 'resultant': [2665], 'crude': [2666], 'membranes': [2667], 'Briefly,': [2706], '5': [2707, 2744, 2829, 3058], 'proteins': [2711, 2895, 2957, 2962, 3019, 3040, 3360, 3521, 4381], 'pm': [2716], '25': [2719], '°C': [2720, 2883, 2905, 3133, 3187], '90': [2722], 'bovine': [2731, 3054], 'albumin': [2733], '(1': [2734], 'mg/ml),': [2735, 2740, 2743], 'bacitracin': [2741], '(0.5': [2742], 'MgSO4': [2746], '(binding': [2747], 'buffer).': [2748, 3062], 'Nonspecific': [2749], 'determined': [2752], 'μm': [2758, 2811], 'Samples': [2760], '10,000': [2764], '10': [2768, 3129, 3706, 3804, 4261], '°C.': [2772], 'washed': [2776, 2815, 2929], 'twice': [2777, 2816, 2930], 'ice-cold': [2779], 'buffer,': [2781], 'radioactivity': [2784, 2801], 'measured.': [2789], 'Specific': [2790], 'calculated': [2793], 'difference': [2796], 'between': [2797, 3193], 'amount': [2799, 3437, 3620, 3673, 3713, 4230, 4249], 'bound': [2802], 'absence': [2805], 'collected': [2818], 'phosphate-buffered': [2820], 'saline.': [2821], 'centrifugation': [2823], '1000': [2825], 'solubilized': [2836, 2956, 3516], 'buffer': [2841, 2923, 2932, 2942, 2950, 3045], '7.5)': [2843], '140': [2845], 'NaCl,': [2847], 'EDTA,': [2850], '0.1': [2851, 2856], 'mg/ml': [2852, 3053], 'phenylmethylsulfonyl': [2858], 'fluoride': [2859], '(buffer': [2860], 'A)': [2861], '1.5%': [2866, 3518], '0.5': [2869], 'sodium': [2871], 'orthovanadate.': [2872], 'mixture': [2874], 'gently': [2876], 'agitated': [2877], 'thereafter': [2885], '13,000': [2888], '20': [2892], 'min.': [2893, 3733, 3805], 'Soluble': [2894, 3520], '(300–500': [2896], 'μg)': [2897, 2959], 'either': [2907, 2937, 3526, 3836, 4234], 'anti-SHP-1,': [2908, 2979], 'anti-sst2,': [2909, 2980], 'anti-G': [2910, 2983], 'preimmune': [2914, 3425, 3553], 'prebound': [2916], 'prewashed': [2921], 'μl': [2939, 2947], 'sample': [2941], 'immunoblotting': [2944, 3328, 3379, 3545, 3630, 4100, 4395], '180': [2946], 'assay.': [2953], 'immunoblotting,': [2955], '(90': [2958], '(see': [2963], 'above)': [2964], 'resolved': [2966], '7.5%': [2968, 3539], 'SDS-polyacrylamide': [2969], 'gels,': [2970], 'transferred': [2971], 'membrane,': [2975], 'immunoblotted': [2977, 3834], 'anti-phosphotyrosine': [2981, 3837], '(35Cambillau': [2989], 'Sarfati': [2993], 'Fanjul': [2999], 'Svoboda': [3001], 'Hollande': [3005], '136:': [3013], '5476-5484Crossref': [3014], 'Immunoreactive': [3018], 'visualized': [3021], 'quantified': [3028], 'image': [3030, 3579], 'Biocom': [3034], 'apparatus': [3035], '(Biocom,': [3036], 'Paris,': [3037], 'Immunoprecipitated': [3039], '7),': [3051], 'albumin,': [3056], 'dithiothreitol': [3060], '(PTPase': [3061], 'substrate': [3064], 'poly(Glu,': [3065, 3122], 'Tyr)': [3066, 3123], 'reaction': [3111], 'addition': [3116, 4147], '30,000': [3118], 'cpm': [3119], '33P-labeled': [3121], 'allowed': [3125], 'proceed': [3127], 'picomoles': [3178], 'inorganic': [3180], 'phosphate': [3181], 'released': [3182], 'per': [3183], 'radiolabeled': [3189], 'substrate.': [3190], 'Statistical': [3191], 'comparison': [3192], 'SMS-treated': [3194, 3822], 'nontreated': [3196], "Student's": [3201], 'pairedt': [3202], 'test.': [3203], 'We': [3204, 3734, 3806, 4361], 'had': [3205], 'reported': [3207, 3331, 3928], 'stimulated': [3218], 'Furthermore,': [3256, 3994], 'endogenous': [3263], 'To': [3300, 3582, 4080, 4180, 4291], 'investigate': [3301, 4181], 'whether': [3302, 3584, 4182], 'interacts': [3304], 'stably': [3308, 4362], 'CHO/sst2-SHP-1': [3316, 3374, 3500, 3502, 3596, 3745, 4041, 4095, 4194, 4390], '95': [3324], 'kDa': [3325], 'detected': [3326, 4139, 4259], '68': [3356], 'whereas': [3358], 'barely': [3362], 'detectable': [3363], 'wild': [3365], '(Fig.': [3368, 3863, 4144, 4396], '1).': [3369], 'immunoprecipitates': [3371, 3444, 3694, 3719, 4063, 4093, 4143], 'prepared': [3372], 'examined': [3377, 3808], 'Fig.2,': [3388], '68-kDa': [3390], 'coprecipitated': [3394], '95-kDa': [3397], 'protein.': [3399, 4079], 'immunoprecipitation': [3402, 3615, 3829], 'coimmunoprecipitation': [3406], 'These': [3411], 'bands': [3413], 'not': [3415, 4014, 4157], 'seen': [3416], 'immunoprecipitations': [3418], 'instead': [3427], 'immune': [3429], 'serum.': [3430], 'Quantification': [3431], 'immunoblots': [3433], 'revealed': [3434, 3843], 'present': [3440, 4126], '(lane': [3445], 'ip': [3446], 'SHP-1-blot': [3447], 'sst2)': [3448], 'represents': [3449, 3467], 'approximately': [3450], '17–20%': [3451], '(ip': [3455], 'sst2-blot': [3456], 'sst2).': [3457], 'Taking': [3458], 'account': [3460], 'efficiency': [3462], 'immunoprecipitation,': [3465], 'about': [3468, 3696], '5%': [3469], 'total': [3471], 'cellular': [3472], 'From': [3474], 'results,': [3476], 'conclude': [3478], 'physically': [3481], 'complexes': [3488, 3534, 3702], 'preformed': [3490, 3700, 3905], 'resting': [3492], 'cells.Figure': [3493], '2Association': [3494], '(106cells/dish)': [3504], 'CHAPS.': [3519], '(ip)': [3524], '(sst2)': [3528], '(SHP-1)': [3531], 'antibodies.': [3532, 3618, 3840], 'Immune': [3533], 'fractionated': [3536], 'SDS-PAGE': [3540], 'subjected': [3542, 3827], 'sequential': [3544], '(blot)': [3546], '(PI).Arrows': [3555], 'indicate': [3556, 3893], 'position': [3558], 'Size': [3563], 'markers': [3564], '(kDa)': [3565], 'left': [3570], 'immunoblot.View': [3573], 'Large': [3574], 'Image': [3575], 'Figure': [3576], 'ViewerDownload': [3577], 'Hi-res': [3578], 'Download': [3580], '(PPT)': [3581], 'determine': [3583], 'interaction': [3586], 'affected': [3592], 'prior': [3611], 'solubilization': [3613], 'analyzed': [3628, 4098], 'blots': [3636], 'reprobed': [3638], 'ensure': [3643], 'comparable': [3645], 'amounts': [3646], 'each': [3653], 'time': [3654, 4267], 'point': [3655, 4318], 'treatment.': [3658, 3710, 4265], 'observed': [3660, 3870, 4215, 4388], 'Fig.': [3662, 3776, 4217], '3,': [3663], 'treatment': [3665, 3728, 3783, 3798, 3813, 4220], 'within': [3680], 'first': [3682], 's': [3684, 3795, 3875, 4227], 'which': [3686, 3761, 3908, 4240, 4327], 'rate': [3688], 'immunodetected': [3690, 3715, 4251], 'decreased,': [3695], '80%': [3697], 'being': [3703], 'dissociated': [3704], 'decreased': [3721], '60': [3723], '±': [3724], '6%': [3725], 'following': [3726], 'further': [3735], 'investigated': [3736], 'times,': [3759], 'they': [3762], 'solubilized,': [3764], 'immunoprecipitates.': [3772, 4213], '4,': [3777], 'increased': [3781], 'upon': [3782], 'maximal': [3792, 3880], 'slightly': [3800], 'declined': [3801, 3885], 'up': [3802], 'untreated': [3824, 3850], 'immunoblot': [3842], '5).': [3864], 'subsequently': [3886], 'until': [3887], 'levels.': [3889], 'All': [3890, 4162], 'subsequent': [3902], 'complexes,': [3907, 4089], 'indicating': [3945], 'sensitive': [3950], 'toxin-sensitive': [4007, 4077], 'proteins,': [4009], 'Goα2,': [4012], 'but': [4013, 4156], 'Giα1': [4016], 'Giα2': [4018], '(36Law': [4019], '10721-10727Abstract': [4032], 'Preincubation': [4039], '18': [4047], '100': [4050], 'ng/ml': [4051], '(not': [4064, 4160], 'shown)': [4065], 'sst2-coupled': [4068], 'directed': [4103], 'Giα1,': [4105, 4133], '2,': [4106], 'Goα1–2': [4109], 'subunits.': [4110], 'well': [4118], 'contrast,': [4132], 'Goα': [4136], 'never': [4138], '6).': [4145], 'anti-Giα3': [4154], 'Goαantibodies': [4159], 'shown).': [4161], 'argue': [4165], 'favor': [4167], 'formation': [4175], 'somatostatin,': [4193], 'treated': [4197], '6,': [4218], 'followed': [4242], 'decrease': [4246], 'Giα3.': [4252], 'Only': [4253], '30%': [4254], 'sst2-associated': [4256], 'course': [4268], 'paralleled': [4276], 'linked.': [4290], 'obtain': [4292], 'proliferation,': [4308], 'catalytically': [4312], 'introducing': [4316], 'conserved': [4322], 'residue,': [4324], 'cysteine': [4325], '453,': [4326], 'crucial': [4329], 'Cys453': [4336], 'mutated': [4338], 'Ser.': [4340], 'This': [4341], 'completely': [4343], 'transiently': [4352], 'COS-7': [4355], '2C.': [4357], 'Nahmias,': [4358], 'unpublished': [4359], 'results.': [4360], 'selected': [4374], '(CHO/sst2-SHP-1(C453S))': [4376], '7).': [4397], 'CHO/sst2-SHP-1(C453S)': [4398], 'S': [4403]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2091783071', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 3}, {'year': 2018, 'cited_by_count': 4}, {'year': 2017, 'cited_by_count': 3}, {'year': 2016, 'cited_by_count': 3}, {'year': 2015, 'cited_by_count': 3}, {'year': 2014, 'cited_by_count': 3}, {'year': 2013, 'cited_by_count': 3}, {'year': 2012, 'cited_by_count': 4}], 'updated_date': '2024-12-10T21:54:33.740706', 'created_date': '2016-06-24'}