Publication Information

{'id': 'https://openalex.org/W2086739992', 'doi': 'https://doi.org/10.1155/np.2004.77', 'title': 'Experimental Investigations on Dopamine Transmission Can Provide Clues on the Mechanism of the Therapeutic Effect of Amphetamine and Methylphenidate in ADHD', 'display_name': 'Experimental Investigations on Dopamine Transmission Can Provide Clues on the Mechanism of the Therapeutic Effect of Amphetamine and Methylphenidate in ADHD', 'publication_year': 2000, 'publication_date': '2000-01-01', 'ids': {'openalex': 'https://openalex.org/W2086739992', 'doi': 'https://doi.org/10.1155/np.2004.77', 'mag': '2086739992', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/15303307', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/2565436'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1155/np.2004.77', 'pdf_url': 'https://downloads.hindawi.com/journals/np/2004/808521.pdf', 'source': {'id': 'https://openalex.org/S185020647', 'display_name': 'Neural Plasticity', 'issn_l': '1687-5443', 'issn': ['1687-5443', '2090-5904'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319869', 'host_organization_name': 'Hindawi Publishing Corporation', 'host_organization_lineage': ['https://openalex.org/P4310319869'], 'host_organization_lineage_names': ['Hindawi Publishing Corporation'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'doaj', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://downloads.hindawi.com/journals/np/2004/808521.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5061948437', 'display_name': 'Ezio Carboni', 'orcid': 'https://orcid.org/0000-0001-8368-1937'}, 'institutions': [{'id': 'https://openalex.org/I172446870', 'display_name': 'University of Cagliari', 'ror': 'https://ror.org/003109y17', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I172446870']}], 'countries': ['IT'], 'is_corresponding': True, 'raw_author_name': 'Ezio Carboni', 'raw_affiliation_strings': ['Department of Toxicology and "Centro di Eccellenza sulla Neurobiologia delle Dipendenze University of Cagliari", Via Ospedale 72, Cagliari 09124'], 'affiliations': [{'raw_affiliation_string': 'Department of Toxicology and "Centro di Eccellenza sulla Neurobiologia delle Dipendenze University of Cagliari", Via Ospedale 72, Cagliari 09124', 'institution_ids': ['https://openalex.org/I172446870']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5041254091', 'display_name': 'Alessandra Silvagni', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I172446870', 'display_name': 'University of Cagliari', 'ror': 'https://ror.org/003109y17', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I172446870']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Alessandra Silvagni', 'raw_affiliation_strings': ['Department of Toxicology and "Centro di Eccellenza sulla Neurobiologia delle Dipendenze University of Cagliari", Via Ospedale 72, Cagliari 09124'], 'affiliations': [{'raw_affiliation_string': 'Department of Toxicology and "Centro di Eccellenza sulla Neurobiologia delle Dipendenze University of Cagliari", Via Ospedale 72, Cagliari 09124', 'institution_ids': ['https://openalex.org/I172446870']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5061948437'], 'corresponding_institution_ids': ['https://openalex.org/I172446870'], 'apc_list': {'value': 2100, 'currency': 'USD', 'value_usd': 2100, 'provenance': 'doaj'}, 'apc_paid': {'value': 2100, 'currency': 'USD', 'value_usd': 2100, 'provenance': 'doaj'}, 'fwci': 0.0, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 34, 'citation_normalized_percentile': {'value': 0.467742, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 89, 'max': 90}, 'biblio': {'volume': '11', 'issue': '1-2', 'first_page': '77', 'last_page': '95'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10537', 'display_name': 'Attention Deficit Hyperactivity Disorder', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2738', 'display_name': 'Psychiatry and Mental health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10537', 'display_name': 'Attention Deficit Hyperactivity Disorder', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2738', 'display_name': 'Psychiatry and Mental health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10056', 'display_name': 'Neurotransmitter Receptor Influence on Behavior', 'score': 0.9992, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11071', 'display_name': 'Treatment of Major Depression', 'score': 0.9791, 'subfield': {'id': 'https://openalex.org/subfields/2736', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/dextroamphetamine', 'display_name': 'Dextroamphetamine', 'score': 0.7156664}], 'concepts': [{'id': 'https://openalex.org/C2777112843', 'wikidata': 'https://www.wikidata.org/wiki/Q422112', 'display_name': 'Methylphenidate', 'level': 3, 'score': 0.9612291}, {'id': 'https://openalex.org/C2777193897', 'wikidata': 'https://www.wikidata.org/wiki/Q179452', 'display_name': 'Amphetamine', 'level': 3, 'score': 0.89202195}, {'id': 'https://openalex.org/C89611455', 'wikidata': 'https://www.wikidata.org/wiki/Q6804646', 'display_name': 'Mechanism (biology)', 'level': 2, 'score': 0.7756671}, {'id': 'https://openalex.org/C513476851', 'wikidata': 'https://www.wikidata.org/wiki/Q170304', 'display_name': 'Dopamine', 'level': 2, 'score': 0.76721376}, {'id': 'https://openalex.org/C2776145449', 'wikidata': 'https://www.wikidata.org/wiki/Q1706418', 'display_name': 'Dextroamphetamine', 'level': 4, 'score': 0.7156664}, {'id': 'https://openalex.org/C169760540', 'wikidata': 'https://www.wikidata.org/wiki/Q207011', 'display_name': 'Neuroscience', 'level': 1, 'score': 0.51914424}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.41325215}, {'id': 'https://openalex.org/C15744967', 'wikidata': 'https://www.wikidata.org/wiki/Q9418', 'display_name': 'Psychology', 'level': 0, 'score': 0.38968468}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.33820885}, {'id': 'https://openalex.org/C118552586', 'wikidata': 'https://www.wikidata.org/wiki/Q7867', 'display_name': 'Psychiatry', 'level': 1, 'score': 0.31345344}, {'id': 'https://openalex.org/C2780783007', 'wikidata': 'https://www.wikidata.org/wiki/Q181923', 'display_name': 'Attention deficit hyperactivity disorder', 'level': 2, 'score': 0.22668499}, {'id': 'https://openalex.org/C138885662', 'wikidata': 'https://www.wikidata.org/wiki/Q5891', 'display_name': 'Philosophy', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C111472728', 'wikidata': 'https://www.wikidata.org/wiki/Q9471', 'display_name': 'Epistemology', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000661', 'descriptor_name': 'Amphetamine', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D001289', 'descriptor_name': 'Attention Deficit Disorder with Hyperactivity', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D004195', 'descriptor_name': 'Disease Models, Animal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D004298', 'descriptor_name': 'Dopamine', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D008774', 'descriptor_name': 'Methylphenidate', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D009435', 'descriptor_name': 'Synaptic Transmission', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D000661', 'descriptor_name': 'Amphetamine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001289', 'descriptor_name': 'Attention Deficit Disorder with Hyperactivity', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D001289', 'descriptor_name': 'Attention Deficit Disorder with Hyperactivity', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D001289', 'descriptor_name': 'Attention Deficit Disorder with Hyperactivity', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004298', 'descriptor_name': 'Dopamine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008774', 'descriptor_name': 'Methylphenidate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009435', 'descriptor_name': 'Synaptic Transmission', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D009435', 'descriptor_name': 'Synaptic Transmission', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 5, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1155/np.2004.77', 'pdf_url': 'https://downloads.hindawi.com/journals/np/2004/808521.pdf', 'source': {'id': 'https://openalex.org/S185020647', 'display_name': 'Neural Plasticity', 'issn_l': '1687-5443', 'issn': ['1687-5443', '2090-5904'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319869', 'host_organization_name': 'Hindawi Publishing Corporation', 'host_organization_lineage': ['https://openalex.org/P4310319869'], 'host_organization_lineage_names': ['Hindawi Publishing Corporation'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://doaj.org/article/6ba989d8487145bc97af716912b3b6d9', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306401280', 'display_name': 'DOAJ (DOAJ: Directory of Open Access Journals)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc2565436', 'pdf_url': 'https://europepmc.org/articles/pmc2565436?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'other-oa', 'license_id': 'https://openalex.org/licenses/other-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2565436', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/15303307', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1155/np.2004.77', 'pdf_url': 'https://downloads.hindawi.com/journals/np/2004/808521.pdf', 'source': {'id': 'https://openalex.org/S185020647', 'display_name': 'Neural Plasticity', 'issn_l': '1687-5443', 'issn': ['1687-5443', '2090-5904'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319869', 'host_organization_name': 'Hindawi Publishing Corporation', 'host_organization_lineage': ['https://openalex.org/P4310319869'], 'host_organization_lineage_names': ['Hindawi Publishing Corporation'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.57}], 'grants': [{'funder': 'https://openalex.org/F4320321873', 'funder_display_name': 'Ministero dell’Istruzione, dell’Università e della Ricerca', 'award_id': None}], 'datasets': [], 'versions': [], 'referenced_works_count': 53, 'referenced_works': ['https://openalex.org/W1572935117', 'https://openalex.org/W1895466054', 'https://openalex.org/W1963153802', 'https://openalex.org/W1978427046', 'https://openalex.org/W1979816765', 'https://openalex.org/W1981025189', 'https://openalex.org/W1985223881', 'https://openalex.org/W1985463855', 'https://openalex.org/W1987965865', 'https://openalex.org/W1987976027', 'https://openalex.org/W1990014976', 'https://openalex.org/W1995883459', 'https://openalex.org/W1997395040', 'https://openalex.org/W1998668957', 'https://openalex.org/W2004866911', 'https://openalex.org/W2011854027', 'https://openalex.org/W2013024853', 'https://openalex.org/W2013302755', 'https://openalex.org/W2014394796', 'https://openalex.org/W2014793858', 'https://openalex.org/W2016228826', 'https://openalex.org/W2021223587', 'https://openalex.org/W2030419485', 'https://openalex.org/W2033411889', 'https://openalex.org/W2036629661', 'https://openalex.org/W2039450868', 'https://openalex.org/W2044907318', 'https://openalex.org/W2050760271', 'https://openalex.org/W2053644167', 'https://openalex.org/W2055073544', 'https://openalex.org/W2059179275', 'https://openalex.org/W2066562577', 'https://openalex.org/W2072190183', 'https://openalex.org/W2073505373', 'https://openalex.org/W2079097047', 'https://openalex.org/W2084057859', 'https://openalex.org/W2086915118', 'https://openalex.org/W2087117829', 'https://openalex.org/W2095434227', 'https://openalex.org/W2098677721', 'https://openalex.org/W2111112265', 'https://openalex.org/W2113065987', 'https://openalex.org/W2114949911', 'https://openalex.org/W2117518771', 'https://openalex.org/W2126680030', 'https://openalex.org/W2136808195', 'https://openalex.org/W2138563618', 'https://openalex.org/W2142415089', 'https://openalex.org/W2150382017', 'https://openalex.org/W2153898074', 'https://openalex.org/W2169328132', 'https://openalex.org/W2169956585', 'https://openalex.org/W2171346733'], 'related_works': ['https://openalex.org/W3034096911', 'https://openalex.org/W2982360720', 'https://openalex.org/W2149605430', 'https://openalex.org/W2070698172', 'https://openalex.org/W2054440001', 'https://openalex.org/W2031643992', 'https://openalex.org/W2023445349', 'https://openalex.org/W1605510982', 'https://openalex.org/W1487622955', 'https://openalex.org/W132763222'], 'abstract_inverted_index': {'The': [0, 107, 140, 170], 'aim': [1], 'of': [2, 19, 33, 48, 50, 57, 65, 92, 137, 179, 201, 221], 'this': [3], 'review': [4], 'is': [5, 149], 'to': [6, 122], 'compare': [7], 'the': [8, 17, 27, 43, 46, 51, 55, 63, 71, 101, 176, 198, 217], 'experimental': [9, 109], 'evidence': [10], 'obtained': [11, 29, 73], 'from': [12, 74, 87], 'in': [13, 30, 54, 75, 82, 88, 117, 120, 151, 165, 175, 206, 210, 232], 'vitro': [14, 76], 'studies': [15], 'on': [16, 23, 45, 203], 'effect': [18, 200, 220], 'amphetamine': [20, 127, 144], 'and': [21, 59, 84, 86, 100, 114, 128, 192], 'methylphenidate': [22, 202], 'dopamine': [24, 147, 157, 172, 204], 'transmission': [25, 173], 'with': [26], 'results': [28, 72, 113], 'animal': [31, 90], 'models': [32, 91], 'attention': [34], 'deficit': [35], 'hyperactivity': [36], 'disorder': [37], '(ADHD).': [38], 'This': [39, 213], 'comparison': [40], 'can': [41, 185], 'extend': [42], 'knowledge': [44], 'mechanism': [47], 'action': [49, 226], 'drugs': [52], 'used': [53], 'therapy': [56], 'ADHD': [58], 'provide': [60], 'insight': [61], 'into': [62], 'etiology': [64], 'ADHD.': [66], 'In': [67], 'particular,': [68], 'we': [69], 'considered': [70], 'methods,': [77], 'such': [78, 94], 'as': [79, 95], 'synaptosomes,': [80], 'cells': [81], 'culture,': [83], 'slices': [85], 'vivo': [89], 'ADHD,': [93], 'spontaneous': [96], 'hypertensive': [97], 'rats': [98, 125, 184], '(SHR)': [99], 'Naples': [102], 'high-excitability': [103], '(NHE)': [104], 'rat': [105], 'lines.': [106], 'different': [108, 135, 230], 'approaches': [110], 'produce': [111], 'consonant': [112], 'suggest': [115], 'that': [116, 148], 'SHR': [118, 180, 207], 'rats,': [119], 'contrast': [121], 'Wistar': [123], 'Kyoto': [124], '(WKY),': [126], 'depolarization': [129], 'by': [130, 143, 159, 188], 'high': [131, 160], 'K+': [132, 161], 'might': [133, 145, 162, 196, 215], 'release': [134, 205], 'pools': [136], 'dopamine-containing': [138], 'vesicles.': [139], 'pool': [141], 'depleted': [142], 'represent': [146], 'stored': [150], 'large': [152], 'dense': [153], 'core': [154], 'vesicles,': [155], 'whereas': [156], 'released': [158], 'be': [163, 186], 'contained': [164], 'small': [166], 'synaptic': [167], 'vesicles': [168], '(SSV).': [169], 'sustained': [171], 'observed': [174], 'nucleus': [177], 'accumbens': [178], 'but': [181, 208], 'not': [182, 209], 'WKY': [183, 211], 'supported': [187], 'an': [189], 'elevated': [190], 'synthesis': [191], 'release,': [193], 'which': [194], 'also': [195], 'explain': [197], 'stronger': [199], 'rats.': [212], 'hypothesis': [214], 'enlighten': [216], 'common': [218], 'therapeutic': [219], 'these': [222], 'drugs,': [223], 'although': [224], 'their': [225], 'takes': [227], 'place': [228], 'at': [229], 'levels': [231], 'catecholaminergic': [233], 'transmission.': [234]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2086739992', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2024-12-13T20:32:23.984435', 'created_date': '2016-06-24'}