Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2082773871', 'doi': 'https://doi.org/10.1016/s0092-8674(00)80576-0', 'title': 'Sprouty, an Intracellular Inhibitor of Ras Signaling', 'display_name': 'Sprouty, an Intracellular Inhibitor of Ras Signaling', 'publication_year': 1999, 'publication_date': '1999-03-01', 'ids': {'openalex': 'https://openalex.org/W2082773871', 'doi': 'https://doi.org/10.1016/s0092-8674(00)80576-0', 'mag': '2082773871', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/10089881'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/s0092-8674(00)80576-0', 'pdf_url': 'http://www.cell.com/article/S0092867400805760/pdf', 'source': {'id': 'https://openalex.org/S110447773', 'display_name': 'Cell', 'issn_l': '0092-8674', 'issn': ['0092-8674', '1097-4172'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315673', 'host_organization_name': 'Cell Press', 'host_organization_lineage': ['https://openalex.org/P4310315673', 'https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Cell Press', 'Elsevier BV'], 'type': 'journal'}, 'license': 'publisher-specific-oa', 'license_id': 'https://openalex.org/licenses/publisher-specific-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'http://www.cell.com/article/S0092867400805760/pdf', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5014253330', 'display_name': 'Tanita Casci', 'orcid': 'https://orcid.org/0000-0002-1838-0027'}, 'institutions': [{'id': 'https://openalex.org/I170203145', 'display_name': 'MRC Laboratory of Molecular Biology', 'ror': 'https://ror.org/00tw3jy02', 'country_code': 'GB', 'type': 'facility', 'lineage': ['https://openalex.org/I170203145', 'https://openalex.org/I4210087105', 'https://openalex.org/I90344618']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Tanita Casci', 'raw_affiliation_strings': ['MRC Laboratory of Molecular Biology Hills Road Cambridge CB2 2QH United Kingdom'], 'affiliations': [{'raw_affiliation_string': 'MRC Laboratory of Molecular Biology Hills Road Cambridge CB2 2QH United Kingdom', 'institution_ids': ['https://openalex.org/I170203145']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5089607648', 'display_name': 'Javier Vinós', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I170203145', 'display_name': 'MRC Laboratory of Molecular Biology', 'ror': 'https://ror.org/00tw3jy02', 'country_code': 'GB', 'type': 'facility', 'lineage': ['https://openalex.org/I170203145', 'https://openalex.org/I4210087105', 'https://openalex.org/I90344618']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Javier Vinós', 'raw_affiliation_strings': ['MRC Laboratory of Molecular Biology Hills Road Cambridge CB2 2QH United Kingdom'], 'affiliations': [{'raw_affiliation_string': 'MRC Laboratory of Molecular Biology Hills Road Cambridge CB2 2QH United Kingdom', 'institution_ids': ['https://openalex.org/I170203145']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5077045618', 'display_name': 'Matthew Freeman', 'orcid': 'https://orcid.org/0000-0003-0410-5451'}, 'institutions': [{'id': 'https://openalex.org/I170203145', 'display_name': 'MRC Laboratory of Molecular Biology', 'ror': 'https://ror.org/00tw3jy02', 'country_code': 'GB', 'type': 'facility', 'lineage': ['https://openalex.org/I170203145', 'https://openalex.org/I4210087105', 'https://openalex.org/I90344618']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Matthew Freeman', 'raw_affiliation_strings': ['MRC Laboratory of Molecular Biology Hills Road Cambridge CB2 2QH United Kingdom'], 'affiliations': [{'raw_affiliation_string': 'MRC Laboratory of Molecular Biology Hills Road Cambridge CB2 2QH United Kingdom', 'institution_ids': ['https://openalex.org/I170203145']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 10100, 'currency': 'USD', 'value_usd': 10100, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 11.106, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 462, 'citation_normalized_percentile': {'value': 0.999971, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '96', 'issue': '5', 'first_page': '655', 'last_page': '665'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12287', 'display_name': 'Fibroblast Growth Factor Research', 'score': 0.999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12287', 'display_name': 'Fibroblast Growth Factor Research', 'score': 0.999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12065', 'display_name': 'Hippo pathway signaling and YAP/TAZ', 'score': 0.9877, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T13426', 'display_name': 'Kruppel-like factors research', 'score': 0.9873, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/cell-surface-receptor', 'display_name': 'Cell surface receptor', 'score': 0.46955305}, {'id': 'https://openalex.org/keywords/receptor-protein-tyrosine-kinases', 'display_name': 'Receptor Protein-Tyrosine Kinases', 'score': 0.4115099}], 'concepts': [{'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.8537934}, {'id': 'https://openalex.org/C79879829', 'wikidata': 'https://www.wikidata.org/wiki/Q5571762', 'display_name': 'Intracellular', 'level': 2, 'score': 0.74434316}, {'id': 'https://openalex.org/C62478195', 'wikidata': 'https://www.wikidata.org/wiki/Q828130', 'display_name': 'Signal transduction', 'level': 2, 'score': 0.7225081}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.7158015}, {'id': 'https://openalex.org/C101544691', 'wikidata': 'https://www.wikidata.org/wiki/Q420511', 'display_name': 'Receptor tyrosine kinase', 'level': 3, 'score': 0.7024039}, {'id': 'https://openalex.org/C28406088', 'wikidata': 'https://www.wikidata.org/wiki/Q5571762', 'display_name': 'Extracellular', 'level': 2, 'score': 0.6499222}, {'id': 'https://openalex.org/C74373430', 'wikidata': 'https://www.wikidata.org/wiki/Q24727126', 'display_name': 'Fibroblast growth factor', 'level': 3, 'score': 0.61068815}, {'id': 'https://openalex.org/C197462201', 'wikidata': 'https://www.wikidata.org/wiki/Q2476074', 'display_name': 'Cell surface receptor', 'level': 3, 'score': 0.46955305}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.45059264}, {'id': 'https://openalex.org/C2911166042', 'wikidata': 'https://www.wikidata.org/wiki/Q420511', 'display_name': 'Receptor Protein-Tyrosine Kinases', 'level': 4, 'score': 0.4115099}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.30196095}], 'mesh': [{'descriptor_ui': 'D029721', 'descriptor_name': 'Drosophila Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D004331', 'descriptor_name': 'Drosophila melanogaster', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D066246', 'descriptor_name': 'ErbB Receptors', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D019476', 'descriptor_name': 'Insect Proteins', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D020703', 'descriptor_name': 'ras GTPase-Activating Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D018631', 'descriptor_name': 'ras Proteins', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002478', 'descriptor_name': 'Cells, Cultured', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003545', 'descriptor_name': 'Cysteine', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D003545', 'descriptor_name': 'Cysteine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003864', 'descriptor_name': 'Depression, Chemical', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004331', 'descriptor_name': 'Drosophila melanogaster', 'qualifier_ui': 'Q000196', 'qualifier_name': 'embryology', 'is_major_topic': False}, {'descriptor_ui': 'D004331', 'descriptor_name': 'Drosophila melanogaster', 'qualifier_ui': 'Q000254', 'qualifier_name': 'growth & development', 'is_major_topic': False}, {'descriptor_ui': 'D004331', 'descriptor_name': 'Drosophila melanogaster', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D004331', 'descriptor_name': 'Drosophila melanogaster', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D066246', 'descriptor_name': 'ErbB Receptors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005123', 'descriptor_name': 'Eye', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005123', 'descriptor_name': 'Eye', 'qualifier_ui': 'Q000254', 'qualifier_name': 'growth & development', 'is_major_topic': False}, {'descriptor_ui': 'D005123', 'descriptor_name': 'Eye', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D005124', 'descriptor_name': 'Eye Abnormalities', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D005124', 'descriptor_name': 'Eye Abnormalities', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005136', 'descriptor_name': 'Eye Proteins', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D005136', 'descriptor_name': 'Eye Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019476', 'descriptor_name': 'Insect Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D019476', 'descriptor_name': 'Insect Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D046911', 'descriptor_name': 'Macromolecular Substances', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008562', 'descriptor_name': 'Membrane Glycoproteins', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D008562', 'descriptor_name': 'Membrane Glycoproteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008565', 'descriptor_name': 'Membrane Proteins', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D008565', 'descriptor_name': 'Membrane Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009024', 'descriptor_name': 'Morphogenesis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011506', 'descriptor_name': 'Proteins', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D011506', 'descriptor_name': 'Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020794', 'descriptor_name': 'Receptor Protein-Tyrosine Kinases', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D020794', 'descriptor_name': 'Receptor Protein-Tyrosine Kinases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018631', 'descriptor_name': 'ras Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/s0092-8674(00)80576-0', 'pdf_url': 'http://www.cell.com/article/S0092867400805760/pdf', 'source': {'id': 'https://openalex.org/S110447773', 'display_name': 'Cell', 'issn_l': '0092-8674', 'issn': ['0092-8674', '1097-4172'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315673', 'host_organization_name': 'Cell Press', 'host_organization_lineage': ['https://openalex.org/P4310315673', 'https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Cell Press', 'Elsevier BV'], 'type': 'journal'}, 'license': 'publisher-specific-oa', 'license_id': 'https://openalex.org/licenses/publisher-specific-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/10089881', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/s0092-8674(00)80576-0', 'pdf_url': 'http://www.cell.com/article/S0092867400805760/pdf', 'source': {'id': 'https://openalex.org/S110447773', 'display_name': 'Cell', 'issn_l': '0092-8674', 'issn': ['0092-8674', '1097-4172'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315673', 'host_organization_name': 'Cell Press', 'host_organization_lineage': ['https://openalex.org/P4310315673', 'https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Cell Press', 'Elsevier BV'], 'type': 'journal'}, 'license': 'publisher-specific-oa', 'license_id': 'https://openalex.org/licenses/publisher-specific-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 61, 'referenced_works': ['https://openalex.org/W1434517181', 'https://openalex.org/W1482845445', 'https://openalex.org/W1523264176', 'https://openalex.org/W1537657975', 'https://openalex.org/W1865164120', 'https://openalex.org/W1885511547', 'https://openalex.org/W1938204331', 'https://openalex.org/W1967159767', 'https://openalex.org/W1970396586', 'https://openalex.org/W1978498030', 'https://openalex.org/W1990527048', 'https://openalex.org/W1991760443', 'https://openalex.org/W1999824494', 'https://openalex.org/W2000998483', 'https://openalex.org/W2009235369', 'https://openalex.org/W2009484032', 'https://openalex.org/W2015913211', 'https://openalex.org/W2016049505', 'https://openalex.org/W2017668082', 'https://openalex.org/W2018372349', 'https://openalex.org/W2022029265', 'https://openalex.org/W2022802536', 'https://openalex.org/W2022840517', 'https://openalex.org/W2023417672', 'https://openalex.org/W2028834438', 'https://openalex.org/W2029744627', 'https://openalex.org/W2031976394', 'https://openalex.org/W2032157793', 'https://openalex.org/W2033672366', 'https://openalex.org/W2036207377', 'https://openalex.org/W2038560503', 'https://openalex.org/W2043644025', 'https://openalex.org/W2046238809', 'https://openalex.org/W2052799365', 'https://openalex.org/W2058199749', 'https://openalex.org/W2073033206', 'https://openalex.org/W2073146277', 'https://openalex.org/W2077742489', 'https://openalex.org/W2084996914', 'https://openalex.org/W2086248842', 'https://openalex.org/W2086689509', 'https://openalex.org/W2093351885', 'https://openalex.org/W2100256750', 'https://openalex.org/W2104262655', 'https://openalex.org/W2107409046', 'https://openalex.org/W2108908409', 'https://openalex.org/W2110643873', 'https://openalex.org/W2114101021', 'https://openalex.org/W2116577449', 'https://openalex.org/W2117669008', 'https://openalex.org/W2119937553', 'https://openalex.org/W2132097023', 'https://openalex.org/W2159935247', 'https://openalex.org/W2170231361', 'https://openalex.org/W2171091522', 'https://openalex.org/W2185119839', 'https://openalex.org/W2414950514', 'https://openalex.org/W321588607', 'https://openalex.org/W638911904', 'https://openalex.org/W77923684', 'https://openalex.org/W937760296'], 'related_works': ['https://openalex.org/W2795353688', 'https://openalex.org/W2755584095', 'https://openalex.org/W2198509606', 'https://openalex.org/W2126073113', 'https://openalex.org/W2088346679', 'https://openalex.org/W2086259825', 'https://openalex.org/W2075091575', 'https://openalex.org/W2071513467', 'https://openalex.org/W2061697147', 'https://openalex.org/W1991624054'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2082773871', 'counts_by_year': [{'year': 2024, 'cited_by_count': 4}, {'year': 2023, 'cited_by_count': 7}, {'year': 2022, 'cited_by_count': 8}, {'year': 2021, 'cited_by_count': 11}, {'year': 2020, 'cited_by_count': 12}, {'year': 2019, 'cited_by_count': 4}, {'year': 2018, 'cited_by_count': 11}, {'year': 2017, 'cited_by_count': 11}, {'year': 2016, 'cited_by_count': 19}, {'year': 2015, 'cited_by_count': 16}, {'year': 2014, 'cited_by_count': 12}, {'year': 2013, 'cited_by_count': 15}, {'year': 2012, 'cited_by_count': 17}], 'updated_date': '2024-12-09T14:15:53.858167', 'created_date': '2016-06-24'}