Effects of Abiraterone Acetate on Androgen Signaling in Castrate-Resistant Prostate Cancer in Bone

Name: Work Video:
Duration: 3 min 30 s
Eleni Efstathiou; Mark Titus; Dimitra Tsavachidou; Vassiliki Tzelepi; Sijin Wen; Anh Hoang; Arturo Molina; Nicole Chieffo; Lisa A. Smith; Μαρία Κάρλου; Patricia Troncoso; Christopher J. Logothetis
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'reaction,': [99], 'TMPRSS2-ERG': [101], 'status': [102], 'fluorescent': [104], 'situ': [106], 'hybridization': [107], 'available': [109], 'tissues.': [110], 'Results': [111], 'Median': [112], 'overall': [113], 'survival': [114], '555': [116], 'days': [117], '(95%': [118], 'CI,': [119], '440': [120], '965+': [122], 'days).': [123], 'Maximal': [124], 'prostate-specific': [125], 'antigen': [126], 'decline': [127], '≥': [128, 145, 173], '50%': [129], 'occurred': [130], '28': [132], '(50%)': [133], '56': [135], 'patients.': [136], 'Homogeneous,': [137], 'intense': [138], 'nuclear': [139], 'AR,': [142], 'combined': [143], '10%': [146, 174], 'tumor': [148, 171], 'expression,': [149], 'correlated': [151, 176], 'longer': [153], 'time': [154], 'treatment': [156], 'discontinuation': [157], '(&gt;': [158], '4': [159], 'months)': [160], '25': [162], 'tumor-infiltrated': [165], 'samples.': [168], 'Pretreatment': [169], 'increased': [178], 'aspirate': [181, 187, 236, 249], 'testosterone.': [182, 259], 'Blood': [183], 'concentrations': [189], 'declined': [190], 'less': [192, 238], 'than': [193, 239], 'picograms-per-milliliter': [194, 240], 'levels': [195], 'remained': [197], 'suppressed': [198], 'at': [199], 'Conclusion': [201], 'The': [202], 'observed': [203], 'pretreatment': [204], 'androgen-signaling': [205], 'signature': [206], 'consistent': [208], 'persistent': [210], 'metastases.': [216], 'the': [219, 255], 'first': [220], 'evidence': [221], 'that': [222], 'achieves': [225], 'sustained': [226], 'suppression': [227], 'both': [231], 'levels.': [241], 'Potential': [242], 'admixture': [243], 'limits': [250], 'our': [251], 'ability': [252], 'determine': [254], 'origin': [256], 'measured': [258]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2080134152', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 5}, {'year': 2022, 'cited_by_count': 7}, {'year': 2021, 'cited_by_count': 5}, {'year': 2020, 'cited_by_count': 6}, {'year': 2019, 'cited_by_count': 6}, {'year': 2018, 'cited_by_count': 8}, {'year': 2017, 'cited_by_count': 7}, {'year': 2016, 'cited_by_count': 21}, {'year': 2015, 'cited_by_count': 16}, {'year': 2014, 'cited_by_count': 42}, {'year': 2013, 'cited_by_count': 42}, {'year': 2012, 'cited_by_count': 17}], 'updated_date': '2024-12-10T23:13:04.994210', 'created_date': '2016-06-24'}
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