Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2077487109', 'doi': 'https://doi.org/10.1002/cbic.201200093', 'title': 'Intrinsically Disordered Proteins: From Sequence and Conformational Properties toward Drug Discovery', 'display_name': 'Intrinsically Disordered Proteins: From Sequence and Conformational Properties toward Drug Discovery', 'publication_year': 2012, 'publication_date': '2012-04-13', 'ids': {'openalex': 'https://openalex.org/W2077487109', 'doi': 'https://doi.org/10.1002/cbic.201200093', 'mag': '2077487109', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/22505141'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/cbic.201200093', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S154285657', 'display_name': 'ChemBioChem', 'issn_l': '1439-4227', 'issn': ['1439-4227', '1439-7633'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5036082816', 'display_name': 'Nasrollah Rezaei‐Ghaleh', 'orcid': 'https://orcid.org/0000-0001-6935-6564'}, 'institutions': [{'id': 'https://openalex.org/I149899117', 'display_name': 'Max Planck Society', 'ror': 'https://ror.org/01hhn8329', 'country_code': 'DE', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I149899117']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Nasrollah Rezaei‐Ghaleh', 'raw_affiliation_strings': ['Department for NMR‐Based Structural Biology, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Goettingen (Germany)'], 'affiliations': [{'raw_affiliation_string': 'Department for NMR‐Based Structural Biology, Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Goettingen (Germany)', 'institution_ids': ['https://openalex.org/I149899117']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5001250430', 'display_name': 'Martin Blackledge', 'orcid': 'https://orcid.org/0000-0003-0935-721X'}, 'institutions': [{'id': 'https://openalex.org/I177483745', 'display_name': 'Université Joseph Fourier', 'ror': 'https://ror.org/02aj0kh94', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I177483745']}, {'id': 'https://openalex.org/I4210152516', 'display_name': 'Institut de Biologie Structurale', 'ror': 'https://ror.org/04szabx38', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I2738703131', 'https://openalex.org/I4210091409', 'https://openalex.org/I4210096427', 'https://openalex.org/I4210152516', 'https://openalex.org/I899635006']}, {'id': 'https://openalex.org/I1294671590', 'display_name': 'Centre National de la Recherche Scientifique', 'ror': 'https://ror.org/02feahw73', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I1294671590']}, {'id': 'https://openalex.org/I3020098449', 'display_name': 'CEA Grenoble', 'ror': 'https://ror.org/02mg6n827', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I2738703131', 'https://openalex.org/I3020098449']}, {'id': 'https://openalex.org/I2738703131', 'display_name': "Commissariat à l'Énergie Atomique et aux Énergies Alternatives", 'ror': 'https://ror.org/00jjx8s55', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I2738703131']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Martin Blackledge', 'raw_affiliation_strings': ['Protein Dynamics and Flexibility, Institut de Biologie Structurale, UMR 5075, CEA‐CNRS‐UJF, 41 rue Jules Horowitz, 38027 Grenoble (France)'], 'affiliations': [{'raw_affiliation_string': 'Protein Dynamics and Flexibility, Institut de Biologie Structurale, UMR 5075, CEA‐CNRS‐UJF, 41 rue Jules Horowitz, 38027 Grenoble (France)', 'institution_ids': ['https://openalex.org/I177483745', 'https://openalex.org/I4210152516', 'https://openalex.org/I1294671590', 'https://openalex.org/I3020098449', 'https://openalex.org/I2738703131']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5033249566', 'display_name': 'Markus Zweckstetter', 'orcid': 'https://orcid.org/0000-0002-2536-6581'}, 'institutions': [{'id': 'https://openalex.org/I149899117', 'display_name': 'Max Planck Society', 'ror': 'https://ror.org/01hhn8329', 'country_code': 'DE', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I149899117']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Markus Zweckstetter', 'raw_affiliation_strings': ['Research Group of Protein Structure Determination using NMR, MPI for biophysical chemistry, Max Planck Society'], 'affiliations': [{'raw_affiliation_string': 'Research Group of Protein Structure Determination using NMR, MPI for biophysical chemistry, Max Planck Society', 'institution_ids': ['https://openalex.org/I149899117']}]}], 'countries_distinct_count': 2, 'institutions_distinct_count': 6, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 4020, 'currency': 'USD', 'value_usd': 4020, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.688, 'has_fulltext': False, 'cited_by_count': 93, 'citation_normalized_percentile': {'value': 0.999716, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '13', 'issue': '7', 'first_page': '930', 'last_page': '950'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10044', 'display_name': 'Protein Structure Prediction and Analysis', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10044', 'display_name': 'Protein Structure Prediction and Analysis', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11162', 'display_name': 'Macromolecular Crystallography Techniques', 'score': 0.9982, 'subfield': {'id': 'https://openalex.org/subfields/2505', 'display_name': 'Materials Chemistry'}, 'field': {'id': 'https://openalex.org/fields/25', 'display_name': 'Materials Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T10519', 'display_name': 'Mass Spectrometry Techniques with Proteins', 'score': 0.9934, 'subfield': {'id': 'https://openalex.org/subfields/1607', 'display_name': 'Spectroscopy'}, 'field': {'id': 'https://openalex.org/fields/16', 'display_name': 'Chemistry'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/proteome', 'display_name': 'Proteome', 'score': 0.7041869}, {'id': 'https://openalex.org/keywords/intrinsically-disordered-proteins', 'display_name': 'Intrinsically Disordered Proteins', 'score': 0.605599}, {'id': 'https://openalex.org/keywords/enzyme-structure', 'display_name': 'Enzyme Structure', 'score': 0.532578}, {'id': 'https://openalex.org/keywords/human-proteome-project', 'display_name': 'Human proteome project', 'score': 0.5252366}, {'id': 'https://openalex.org/keywords/protein-identification', 'display_name': 'Protein Identification', 'score': 0.524015}, {'id': 'https://openalex.org/keywords/protein-stability', 'display_name': 'Protein Stability', 'score': 0.519189}, {'id': 'https://openalex.org/keywords/proteins', 'display_name': 'Proteins', 'score': 0.514781}, {'id': 'https://openalex.org/keywords/drug-development', 'display_name': 'Drug development', 'score': 0.42903525}], 'concepts': [{'id': 'https://openalex.org/C2778815515', 'wikidata': 'https://www.wikidata.org/wiki/Q3408242', 'display_name': 'Intrinsically disordered proteins', 'level': 2, 'score': 0.9252056}, {'id': 'https://openalex.org/C70721500', 'wikidata': 'https://www.wikidata.org/wiki/Q177005', 'display_name': 'Computational biology', 'level': 1, 'score': 0.73998374}, {'id': 'https://openalex.org/C74187038', 'wikidata': 'https://www.wikidata.org/wiki/Q1418791', 'display_name': 'Drug discovery', 'level': 2, 'score': 0.70704293}, {'id': 'https://openalex.org/C104397665', 'wikidata': 'https://www.wikidata.org/wiki/Q860947', 'display_name': 'Proteome', 'level': 2, 'score': 0.7041869}, {'id': 'https://openalex.org/C94795543', 'wikidata': 'https://www.wikidata.org/wiki/Q3813754', 'display_name': 'Human proteome project', 'level': 4, 'score': 0.5252366}, {'id': 'https://openalex.org/C14036430', 'wikidata': 'https://www.wikidata.org/wiki/Q3736076', 'display_name': 'Function (biology)', 'level': 2, 'score': 0.5145956}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.43017563}, {'id': 'https://openalex.org/C64903051', 'wikidata': 'https://www.wikidata.org/wiki/Q2198549', 'display_name': 'Drug development', 'level': 3, 'score': 0.42903525}, {'id': 'https://openalex.org/C161624437', 'wikidata': 'https://www.wikidata.org/wiki/Q1988322', 'display_name': 'Small molecule', 'level': 2, 'score': 0.41851774}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.37226227}, {'id': 'https://openalex.org/C46111723', 'wikidata': 'https://www.wikidata.org/wiki/Q471857', 'display_name': 'Proteomics', 'level': 3, 'score': 0.36576393}, {'id': 'https://openalex.org/C171250308', 'wikidata': 'https://www.wikidata.org/wiki/Q11468', 'display_name': 'Nanotechnology', 'level': 1, 'score': 0.3419206}, {'id': 'https://openalex.org/C60644358', 'wikidata': 'https://www.wikidata.org/wiki/Q128570', 'display_name': 'Bioinformatics', 'level': 1, 'score': 0.29799798}, {'id': 'https://openalex.org/C12554922', 'wikidata': 'https://www.wikidata.org/wiki/Q7100', 'display_name': 'Biophysics', 'level': 1, 'score': 0.27758908}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.2740887}, {'id': 'https://openalex.org/C2780035454', 'wikidata': 'https://www.wikidata.org/wiki/Q8386', 'display_name': 'Drug', 'level': 2, 'score': 0.24929643}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.23498666}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.16325933}, {'id': 'https://openalex.org/C192562407', 'wikidata': 'https://www.wikidata.org/wiki/Q228736', 'display_name': 'Materials science', 'level': 0, 'score': 0.1412799}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D011506', 'descriptor_name': 'Proteins', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D000595', 'descriptor_name': 'Amino Acid Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D055808', 'descriptor_name': 'Drug Discovery', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008958', 'descriptor_name': 'Models, Molecular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019906', 'descriptor_name': 'Nuclear Magnetic Resonance, Biomolecular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011487', 'descriptor_name': 'Protein Conformation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017510', 'descriptor_name': 'Protein Folding', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011506', 'descriptor_name': 'Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011506', 'descriptor_name': 'Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D013329', 'descriptor_name': 'Structure-Activity Relationship', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/cbic.201200093', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S154285657', 'display_name': 'ChemBioChem', 'issn_l': '1439-4227', 'issn': ['1439-4227', '1439-7633'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/22505141', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.45, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 210, 'referenced_works': ['https://openalex.org/W126863785', 'https://openalex.org/W1544371346', 'https://openalex.org/W1595368494', 'https://openalex.org/W1680110353', 'https://openalex.org/W1792685479', 'https://openalex.org/W1825536795', 'https://openalex.org/W1861730929', 'https://openalex.org/W1965691764', 'https://openalex.org/W1965887195', 'https://openalex.org/W1967039992', 'https://openalex.org/W1967203779', 'https://openalex.org/W1967638691', 'https://openalex.org/W1967974247', 'https://openalex.org/W1969952127', 'https://openalex.org/W1971398376', 'https://openalex.org/W1972013995', 'https://openalex.org/W1973117210', 'https://openalex.org/W1974607424', 'https://openalex.org/W1975121208', 'https://openalex.org/W1976238793', 'https://openalex.org/W1976261939', 'https://openalex.org/W1976470237', 'https://openalex.org/W1977920759', 'https://openalex.org/W1978313975', 'https://openalex.org/W1979287293', 'https://openalex.org/W1980015132', 'https://openalex.org/W1981868658', 'https://openalex.org/W1982383324', 'https://openalex.org/W1983141756', 'https://openalex.org/W1983404135', 'https://openalex.org/W1985477745', 'https://openalex.org/W1986469135', 'https://openalex.org/W1986859272', 'https://openalex.org/W1988565419', 'https://openalex.org/W1988624456', 'https://openalex.org/W1992017428', 'https://openalex.org/W1993145018', 'https://openalex.org/W1993795908', 'https://openalex.org/W1994151152', 'https://openalex.org/W1995659378', 'https://openalex.org/W1996222219', 'https://openalex.org/W1996518756', 'https://openalex.org/W1996632098', 'https://openalex.org/W1996859443', 'https://openalex.org/W1997477098', 'https://openalex.org/W1997723318', 'https://openalex.org/W1998735636', 'https://openalex.org/W2000052684', 'https://openalex.org/W2000149219', 'https://openalex.org/W2000888492', 'https://openalex.org/W2001746030', 'https://openalex.org/W2002900623', 'https://openalex.org/W2003119577', 'https://openalex.org/W2003154561', 'https://openalex.org/W2004291898', 'https://openalex.org/W2006192061', 'https://openalex.org/W2006600560', 'https://openalex.org/W2007016963', 'https://openalex.org/W2007438323', 'https://openalex.org/W2007829343', 'https://openalex.org/W2008850469', 'https://openalex.org/W2009174018', 'https://openalex.org/W2009284411', 'https://openalex.org/W2012363870', 'https://openalex.org/W2013354180', 'https://openalex.org/W2013491063', 'https://openalex.org/W2013743057', 'https://openalex.org/W2014776147', 'https://openalex.org/W2016158838', 'https://openalex.org/W2016170088', 'https://openalex.org/W2020209643', 'https://openalex.org/W2021332309', 'https://openalex.org/W2023156380', 'https://openalex.org/W2023245921', 'https://openalex.org/W2023487073', 'https://openalex.org/W2025484732', 'https://openalex.org/W2025717854', 'https://openalex.org/W2026717532', 'https://openalex.org/W2026946969', 'https://openalex.org/W2027035874', 'https://openalex.org/W2027517938', 'https://openalex.org/W2027955308', 'https://openalex.org/W2029925798', 'https://openalex.org/W2030207939', 'https://openalex.org/W2030776726', 'https://openalex.org/W2031964854', 'https://openalex.org/W2033782813', 'https://openalex.org/W2033995262', 'https://openalex.org/W2034299708', 'https://openalex.org/W2038895598', 'https://openalex.org/W2040809566', 'https://openalex.org/W2041944326', 'https://openalex.org/W2042316019', 'https://openalex.org/W2042380110', 'https://openalex.org/W2044730187', 'https://openalex.org/W2046366527', 'https://openalex.org/W2048072382', 'https://openalex.org/W2048367443', 'https://openalex.org/W2048917256', 'https://openalex.org/W2049476357', 'https://openalex.org/W2049587523', 'https://openalex.org/W2050855211', 'https://openalex.org/W2051916497', 'https://openalex.org/W2052606462', 'https://openalex.org/W2053202752', 'https://openalex.org/W2053278954', 'https://openalex.org/W2053820259', 'https://openalex.org/W2054191418', 'https://openalex.org/W2054608965', 'https://openalex.org/W2054715902', 'https://openalex.org/W2055193239', 'https://openalex.org/W2055644676', 'https://openalex.org/W2055667207', 'https://openalex.org/W2058158903', 'https://openalex.org/W2058238447', 'https://openalex.org/W2058783229', 'https://openalex.org/W2061134340', 'https://openalex.org/W2061144516', 'https://openalex.org/W2061892659', 'https://openalex.org/W2062557777', 'https://openalex.org/W2063669247', 'https://openalex.org/W2064280962', 'https://openalex.org/W2066041565', 'https://openalex.org/W2067613861', 'https://openalex.org/W2069053167', 'https://openalex.org/W2069321794', 'https://openalex.org/W2069511429', 'https://openalex.org/W2069531090', 'https://openalex.org/W2070496155', 'https://openalex.org/W2070958052', 'https://openalex.org/W2072259830', 'https://openalex.org/W2072654958', 'https://openalex.org/W2074662591', 'https://openalex.org/W2075564615', 'https://openalex.org/W2076662394', 'https://openalex.org/W2077653924', 'https://openalex.org/W2078859886', 'https://openalex.org/W2078933468', 'https://openalex.org/W2084317099', 'https://openalex.org/W2084652316', 'https://openalex.org/W2085656056', 'https://openalex.org/W2085852844', 'https://openalex.org/W2086131123', 'https://openalex.org/W2087774804', 'https://openalex.org/W2088825615', 'https://openalex.org/W2089869461', 'https://openalex.org/W2090167935', 'https://openalex.org/W2091625914', 'https://openalex.org/W2092153867', 'https://openalex.org/W2092818861', 'https://openalex.org/W2093626513', 'https://openalex.org/W2094434685', 'https://openalex.org/W2097933346', 'https://openalex.org/W2098356282', 'https://openalex.org/W2099136664', 'https://openalex.org/W2101137168', 'https://openalex.org/W2101574921', 'https://openalex.org/W2101953406', 'https://openalex.org/W2103743266', 'https://openalex.org/W2106477324', 'https://openalex.org/W2109401365', 'https://openalex.org/W2110128290', 'https://openalex.org/W2113115394', 'https://openalex.org/W2114358470', 'https://openalex.org/W2114823344', 'https://openalex.org/W2118608964', 'https://openalex.org/W2118805990', 'https://openalex.org/W2119693327', 'https://openalex.org/W2120744225', 'https://openalex.org/W2120881407', 'https://openalex.org/W2122806508', 'https://openalex.org/W2123121534', 'https://openalex.org/W2123408027', 'https://openalex.org/W2125751506', 'https://openalex.org/W2126064524', 'https://openalex.org/W2127415878', 'https://openalex.org/W2128021885', 'https://openalex.org/W2131819352', 'https://openalex.org/W2131965976', 'https://openalex.org/W2132163861', 'https://openalex.org/W2132179389', 'https://openalex.org/W2136669014', 'https://openalex.org/W2137212933', 'https://openalex.org/W2138039051', 'https://openalex.org/W2142669003', 'https://openalex.org/W2143608447', 'https://openalex.org/W2144252381', 'https://openalex.org/W2144737808', 'https://openalex.org/W2148321634', 'https://openalex.org/W2148521301', 'https://openalex.org/W2150697021', 'https://openalex.org/W2151061130', 'https://openalex.org/W2152265734', 'https://openalex.org/W2153171611', 'https://openalex.org/W2153970368', 'https://openalex.org/W2155685362', 'https://openalex.org/W2156771958', 'https://openalex.org/W2157580603', 'https://openalex.org/W2161199282', 'https://openalex.org/W2162685411', 'https://openalex.org/W2165890129', 'https://openalex.org/W2168875869', 'https://openalex.org/W2168879529', 'https://openalex.org/W2168970921', 'https://openalex.org/W2316665668', 'https://openalex.org/W2319226565', 'https://openalex.org/W232800751', 'https://openalex.org/W2470665661', 'https://openalex.org/W4210968583', 'https://openalex.org/W4253934345'], 'related_works': ['https://openalex.org/W3092794487', 'https://openalex.org/W3032536091', 'https://openalex.org/W2909412621', 'https://openalex.org/W2885268310', 'https://openalex.org/W2806882504', 'https://openalex.org/W2580329791', 'https://openalex.org/W2575115220', 'https://openalex.org/W2094752534', 'https://openalex.org/W2052894646', 'https://openalex.org/W2025055488'], 'abstract_inverted_index': {'Structural': [0], 'disorder': [1], 'of': [2, 15, 24, 34, 67, 88, 118, 130, 135], 'functional': [3, 25], 'proteins': [4, 30], 'under': [5], 'physiological': [6], 'conditions': [7], 'is': [8, 70], 'widespread': [9], 'within': [10], 'eukaryotic': [11], 'proteomes.': [12], 'The': [13], 'lack': [14], 'stable': [16], 'tertiary': [17], 'and': [18, 43, 62, 65, 79, 101], 'secondary': [19], 'structure': [20], 'offers': [21], 'a': [22], 'variety': [23], 'advantages': [26], 'to': [27, 122, 144], 'intrinsically': [28], 'disordered': [29], '(IDPs):': [31], 'their': [32, 44, 68], 'malleability': [33], 'interaction': [35], 'with': [36, 72], 'different': [37], 'partners,': [38], 'specific': [39], 'but': [40], 'low-affinity': [41], 'binding,': [42], 'fine': [45], 'modulation': [46], 'by': [47, 115], 'post-translational': [48], 'modifications.': [49], 'IDPs': [50, 89], 'are': [51], 'therefore': [52], 'central': [53], 'players': [54], 'in': [55, 84, 93, 98, 108, 126, 148], 'key': [56], 'processes': [57], 'such': [58, 76], 'as': [59, 77, 105, 107], 'cell-cycle': [60], 'control': [61], 'signal-transduction': [63], 'pathways,': [64], 'impairment': [66], 'function': [69], 'associated': [71], 'many': [73], 'disease': [74], 'states': [75], 'cancer': [78], 'neurodegenerative': [80], 'disorders.': [81], 'Fascinating': [82], 'progress': [83], 'the': [85, 94, 116, 133, 142], 'experimental': [86, 124], 'characterization': [87], 'has': [90, 112], 'been': [91, 113], 'made': [92], 'last': [95], 'decade,': [96], 'especially': [97], 'NMR': [99], 'spectroscopy': [100], 'small-angle': [102], 'X-ray': [103], 'scattering': [104], 'well': [106], 'single-molecule': [109], 'techniques.': [110], 'It': [111], 'accompanied': [114], 'development': [117], 'powerful': [119], 'computational': [120], 'tools': [121], 'translate': [123], 'results': [125], 'explicit': [127], 'ensemble': [128], 'representations': [129], 'IDPs.': [131], 'With': [132], 'aid': [134], 'bioinformatics': [136], 'tools,': [137], 'these': [138], 'advances': [139], 'have': [140], 'paved': [141], 'way': [143], 'targeting': [145], 'IDP': [146], 'interactions': [147], 'rational': [149], 'drug-discovery': [150], 'projects.': [151]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2077487109', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 11}, {'year': 2021, 'cited_by_count': 4}, {'year': 2020, 'cited_by_count': 8}, {'year': 2019, 'cited_by_count': 5}, {'year': 2018, 'cited_by_count': 5}, {'year': 2017, 'cited_by_count': 3}, {'year': 2016, 'cited_by_count': 7}, {'year': 2015, 'cited_by_count': 14}, {'year': 2014, 'cited_by_count': 13}, {'year': 2013, 'cited_by_count': 12}, {'year': 2012, 'cited_by_count': 6}], 'updated_date': '2024-08-13T03:54:01.524380', 'created_date': '2016-06-24'}