Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2072311845', 'doi': 'https://doi.org/10.1002/elps.1150181410', 'title': 'Membrane transport in rat liver endocytic pathways: Preparation, biochemical properties and functional roles of hepatic endosomes', 'display_name': 'Membrane transport in rat liver endocytic pathways: Preparation, biochemical properties and functional roles of hepatic endosomes', 'publication_year': 1997, 'publication_date': '1997-01-01', 'ids': {'openalex': 'https://openalex.org/W2072311845', 'doi': 'https://doi.org/10.1002/elps.1150181410', 'mag': '2072311845', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/9527484'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/elps.1150181410', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2849398', 'display_name': 'Electrophoresis', 'issn_l': '0173-0835', 'issn': ['0173-0835', '1522-2683'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5057960764', 'display_name': 'Albert Pol', 'orcid': 'https://orcid.org/0000-0002-1750-1085'}, 'institutions': [{'id': 'https://openalex.org/I71999127', 'display_name': 'Universitat de Barcelona', 'ror': 'https://ror.org/021018s57', 'country_code': 'ES', 'type': 'education', 'lineage': ['https://openalex.org/I71999127']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Albert Pol', 'raw_affiliation_strings': ['Departament de Biologia Cellular, Facultat de Medicina, Universitat de Barcelona, Casanova 143, 08036 Barcelona, Spain (Fax: +343‐4021907)'], 'affiliations': [{'raw_affiliation_string': 'Departament de Biologia Cellular, Facultat de Medicina, Universitat de Barcelona, Casanova 143, 08036 Barcelona, Spain (Fax: +343‐4021907)', 'institution_ids': ['https://openalex.org/I71999127']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5027752685', 'display_name': 'Carlos Enrich', 'orcid': 'https://orcid.org/0000-0003-0382-2993'}, 'institutions': [{'id': 'https://openalex.org/I71999127', 'display_name': 'Universitat de Barcelona', 'ror': 'https://ror.org/021018s57', 'country_code': 'ES', 'type': 'education', 'lineage': ['https://openalex.org/I71999127']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Carlos Enrich', 'raw_affiliation_strings': ['Departament de Biología Cellular, Facultat de Medicina, Universitat de Barcelona, Barcelona, Spain'], 'affiliations': [{'raw_affiliation_string': 'Departament de Biología Cellular, Facultat de Medicina, Universitat de Barcelona, Barcelona, Spain', 'institution_ids': ['https://openalex.org/I71999127']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 4120, 'currency': 'USD', 'value_usd': 4120, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.376, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 20, 'citation_normalized_percentile': {'value': 0.209402, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 84, 'max': 85}, 'biblio': {'volume': '18', 'issue': '14', 'first_page': '2548', 'last_page': '2557'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10617', 'display_name': 'Cellular transport and secretion', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10617', 'display_name': 'Cellular transport and secretion', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10407', 'display_name': 'Lipid Membrane Structure and Behavior', 'score': 0.9989, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11908', 'display_name': 'Protein Interaction Studies and Fluorescence Analysis', 'score': 0.9973, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/compartment', 'display_name': 'Compartment (ship)', 'score': 0.54049474}], 'concepts': [{'id': 'https://openalex.org/C102747710', 'wikidata': 'https://www.wikidata.org/wiki/Q824237', 'display_name': 'Endosome', 'level': 3, 'score': 0.9653958}, {'id': 'https://openalex.org/C79747257', 'wikidata': 'https://www.wikidata.org/wiki/Q189814', 'display_name': 'Endocytic cycle', 'level': 4, 'score': 0.96304643}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.6048799}, {'id': 'https://openalex.org/C203635412', 'wikidata': 'https://www.wikidata.org/wiki/Q17007432', 'display_name': 'Compartment (ship)', 'level': 2, 'score': 0.54049474}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.47111535}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.47040874}, {'id': 'https://openalex.org/C2776200302', 'wikidata': 'https://www.wikidata.org/wiki/Q827450', 'display_name': 'Hepatocyte', 'level': 3, 'score': 0.45548645}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.44871172}, {'id': 'https://openalex.org/C144647389', 'wikidata': 'https://www.wikidata.org/wiki/Q423042', 'display_name': 'Membrane protein', 'level': 3, 'score': 0.44272214}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.42510965}, {'id': 'https://openalex.org/C116084860', 'wikidata': 'https://www.wikidata.org/wiki/Q48255', 'display_name': 'Gel electrophoresis', 'level': 2, 'score': 0.4189309}, {'id': 'https://openalex.org/C28005876', 'wikidata': 'https://www.wikidata.org/wiki/Q189814', 'display_name': 'Endocytosis', 'level': 3, 'score': 0.38840327}, {'id': 'https://openalex.org/C41625074', 'wikidata': 'https://www.wikidata.org/wiki/Q176088', 'display_name': 'Membrane', 'level': 2, 'score': 0.2070736}, {'id': 'https://openalex.org/C111368507', 'wikidata': 'https://www.wikidata.org/wiki/Q43518', 'display_name': 'Oceanography', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C202751555', 'wikidata': 'https://www.wikidata.org/wiki/Q221681', 'display_name': 'In vitro', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C127313418', 'wikidata': 'https://www.wikidata.org/wiki/Q1069', 'display_name': 'Geology', 'level': 0, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D011992', 'descriptor_name': 'Endosomes', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001692', 'descriptor_name': 'Biological Transport', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002458', 'descriptor_name': 'Cell Fractionation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002462', 'descriptor_name': 'Cell Membrane', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015180', 'descriptor_name': 'Electrophoresis, Gel, Two-Dimensional', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': False}, {'descriptor_ui': 'D015180', 'descriptor_name': 'Electrophoresis, Gel, Two-Dimensional', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004705', 'descriptor_name': 'Endocytosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011992', 'descriptor_name': 'Endosomes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/elps.1150181410', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2849398', 'display_name': 'Electrophoresis', 'issn_l': '0173-0835', 'issn': ['0173-0835', '1522-2683'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/9527484', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Clean water and sanitation', 'score': 0.44, 'id': 'https://metadata.un.org/sdg/6'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 42, 'referenced_works': ['https://openalex.org/W1481559242', 'https://openalex.org/W1493984199', 'https://openalex.org/W1504005208', 'https://openalex.org/W1568586029', 'https://openalex.org/W1657488732', 'https://openalex.org/W1755823153', 'https://openalex.org/W1877010584', 'https://openalex.org/W1917903703', 'https://openalex.org/W1949772429', 'https://openalex.org/W1968395750', 'https://openalex.org/W1970902024', 'https://openalex.org/W1971065575', 'https://openalex.org/W1974043466', 'https://openalex.org/W1975205143', 'https://openalex.org/W1981647923', 'https://openalex.org/W1988784064', 'https://openalex.org/W1997107209', 'https://openalex.org/W1997966048', 'https://openalex.org/W2013660714', 'https://openalex.org/W2024576374', 'https://openalex.org/W2044853699', 'https://openalex.org/W2046973476', 'https://openalex.org/W2049713657', 'https://openalex.org/W2050788158', 'https://openalex.org/W2065378127', 'https://openalex.org/W2073547618', 'https://openalex.org/W2075468754', 'https://openalex.org/W2077924138', 'https://openalex.org/W2083453910', 'https://openalex.org/W2097651191', 'https://openalex.org/W2100837269', 'https://openalex.org/W2107265740', 'https://openalex.org/W2124385473', 'https://openalex.org/W2134344512', 'https://openalex.org/W2134748481', 'https://openalex.org/W2143913255', 'https://openalex.org/W2153042101', 'https://openalex.org/W2174160083', 'https://openalex.org/W2206673445', 'https://openalex.org/W4205265939', 'https://openalex.org/W570876575', 'https://openalex.org/W99245710'], 'related_works': ['https://openalex.org/W4281554008', 'https://openalex.org/W3151913394', 'https://openalex.org/W3048027417', 'https://openalex.org/W2830758472', 'https://openalex.org/W2148338791', 'https://openalex.org/W2140820666', 'https://openalex.org/W2124513632', 'https://openalex.org/W2046128749', 'https://openalex.org/W2016622933', 'https://openalex.org/W1492038278'], 'abstract_inverted_index': {'Abstract': [0], 'The': [1, 94, 141], 'endocytic': [2, 89, 134, 166], 'compartment': [3, 37, 50], 'has': [4, 19], 'emerged': [5], 'as': [6], 'a': [7, 74], 'major': [8], 'regulator': [9], 'of': [10, 15, 32, 38, 55, 78, 97, 130, 143], 'the': [11, 24, 30, 33, 69, 87, 98, 111, 127, 131, 151, 164, 169], 'uptake': [12], 'and': [13, 18, 41, 47, 83, 103, 107, 116, 120, 136, 147, 162], 'processing': [14], 'circulating': [16], 'ligands,': [17], 'been': [20], 'extensively': [21], 'studied': [22, 102], 'during': [23], 'last': [25], 'decade.': [26], 'In': [27], 'this': [28], 'work,': [29], 'polypeptides': [31], 'three': [34, 70, 88, 132, 152], 'endosomal': [35, 71, 113, 153], 'fractions:': [36], 'uncoupling': [39], 'receptors': [40], 'ligands': [42, 106, 146], '(CURL),': [43], 'multivesicular': [44], 'bodies': [45], '(MVB)': [46], 'receptor': [48], 'recycling': [49], '(RRC),': [51], 'isolated': [52, 133], 'from': [53], 'livers': [54], 'estradiol‐treated': [56], 'rats,': [57], 'were': [58, 123, 139], 'analyzed': [59], 'by': [60], 'two‐dimensional': [61, 117], 'gel': [62, 118], 'electrophoresis.': [63], 'Silver‐stained': [64], 'gels': [65], 'revealed': [66], 'that': [67], 'although': [68], 'fractions': [72, 90, 135, 154], 'shared': [73], 'generally': [75], 'similar': [76], 'pattern': [77], 'approximately': [79], '120': [80], 'components,': [81], 'qualitative': [82], 'quantitative': [84], 'differences': [85], 'between': [86], 'could': [91], 'be': [92], 'demonstrated.': [93], 'polypeptide': [95], 'composition': [96, 129], 'bile': [99], 'was': [100, 155], 'also': [101], 'compared': [104], 'with': [105, 158, 163], 'proteins': [108, 138, 149], 'identified': [109, 144], 'in': [110, 156, 168], 'different': [112, 165], 'fractions.': [114], 'One‐': [115], 'electrophoresis': [119], 'Western': [121], 'blotting': [122], 'used': [124], 'to': [125], 'investigate': [126], 'protein': [128], '39': [137], 'identified.': [140], 'distribution': [142], 'receptors,': [145], 'structural': [148], 'among': [150], 'agreement': [157], 'their': [159], 'expected': [160], 'functionalities': [161], 'pathways': [167], 'hepatocyte.': [170]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2072311845', 'counts_by_year': [{'year': 2022, 'cited_by_count': 1}], 'updated_date': '2024-12-10T19:27:09.934510', 'created_date': '2016-06-24'}