Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W4281554008', 'doi': 'https://doi.org/10.1242/bio.059150', 'title': 'Pacsin2 is required for endocytosis in the zebrafish pronephric tubule', 'display_name': 'Pacsin2 is required for endocytosis in the zebrafish pronephric tubule', 'publication_year': 2022, 'publication_date': '2022-05-26', 'ids': {'openalex': 'https://openalex.org/W4281554008', 'doi': 'https://doi.org/10.1242/bio.059150', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/35616009'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1242/bio.059150', 'pdf_url': 'https://journals.biologists.com/bio/article-pdf/11/6/bio059150/2149505/bio059150.pdf', 'source': {'id': 'https://openalex.org/S2738063279', 'display_name': 'Biology Open', 'issn_l': '2046-6390', 'issn': ['2046-6390'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311847', 'host_organization_name': 'The Company of Biologists', 'host_organization_lineage': ['https://openalex.org/P4310311847'], 'host_organization_lineage_names': ['The Company of Biologists'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'doaj', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://journals.biologists.com/bio/article-pdf/11/6/bio059150/2149505/bio059150.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5033950733', 'display_name': 'Joseph Morgan', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I28407311', 'display_name': 'University of Manchester', 'ror': 'https://ror.org/027m9bs27', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I28407311']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Joseph Morgan', 'raw_affiliation_strings': ['Biological Sciences , Faculty of Biology, Medicine and Health , , The Michael Smith Building, Oxford Road, Manchester M13 9PT , UK', 'School ofBiological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, The Michael Smith Building, Oxford Road, Manchester M13 9PT, UK', 'University of Manchester , Faculty of Biology, Medicine and Health , , The Michael Smith Building, Oxford Road, Manchester M13 9PT , UK'], 'affiliations': [{'raw_affiliation_string': 'School ofBiological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, The Michael Smith Building, Oxford Road, Manchester M13 9PT, UK', 'institution_ids': ['https://openalex.org/I28407311']}, {'raw_affiliation_string': 'University of Manchester , Faculty of Biology, Medicine and Health , , The Michael Smith Building, Oxford Road, Manchester M13 9PT , UK', 'institution_ids': ['https://openalex.org/I28407311']}, {'raw_affiliation_string': 'Biological Sciences , Faculty of Biology, Medicine and Health , , The Michael Smith Building, Oxford Road, Manchester M13 9PT , UK', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5060375757', 'display_name': 'Rebecca Yarwood', 'orcid': 'https://orcid.org/0000-0002-8287-9420'}, 'institutions': [{'id': 'https://openalex.org/I28407311', 'display_name': 'University of Manchester', 'ror': 'https://ror.org/027m9bs27', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I28407311']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Rebecca Yarwood', 'raw_affiliation_strings': ['Biological Sciences , Faculty of Biology, Medicine and Health , , The Michael Smith Building, Oxford Road, Manchester M13 9PT , UK', 'School ofBiological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, The Michael Smith Building, Oxford Road, Manchester M13 9PT, UK', 'University of Manchester , Faculty of Biology, Medicine and Health , , The Michael Smith Building, Oxford Road, Manchester M13 9PT , UK'], 'affiliations': [{'raw_affiliation_string': 'Biological Sciences , Faculty of Biology, Medicine and Health , , The Michael Smith Building, Oxford Road, Manchester M13 9PT , UK', 'institution_ids': []}, {'raw_affiliation_string': 'University of Manchester , Faculty of Biology, Medicine and Health , , The Michael Smith Building, Oxford Road, Manchester M13 9PT , UK', 'institution_ids': ['https://openalex.org/I28407311']}, {'raw_affiliation_string': 'School ofBiological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, The Michael Smith Building, Oxford Road, Manchester M13 9PT, UK', 'institution_ids': ['https://openalex.org/I28407311']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5060914864', 'display_name': 'Tobias Starborg', 'orcid': 'https://orcid.org/0000-0002-1091-1487'}, 'institutions': [{'id': 'https://openalex.org/I28407311', 'display_name': 'University of Manchester', 'ror': 'https://ror.org/027m9bs27', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I28407311']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Tobias Starborg', 'raw_affiliation_strings': ['Biological Sciences , Faculty of Biology, Medicine and Health , , The Michael Smith Building, Oxford Road, Manchester M13 9PT , UK', 'School ofBiological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, The Michael Smith Building, Oxford Road, Manchester M13 9PT, UK', 'University of Manchester , Faculty of Biology, Medicine and Health , , The Michael Smith Building, Oxford Road, Manchester M13 9PT , UK'], 'affiliations': [{'raw_affiliation_string': 'School ofBiological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, The Michael Smith Building, Oxford Road, Manchester M13 9PT, UK', 'institution_ids': ['https://openalex.org/I28407311']}, {'raw_affiliation_string': 'Biological Sciences , Faculty of Biology, Medicine and Health , , The Michael Smith Building, Oxford Road, Manchester M13 9PT , UK', 'institution_ids': []}, {'raw_affiliation_string': 'University of Manchester , Faculty of Biology, Medicine and Health , , The Michael Smith Building, Oxford Road, Manchester M13 9PT , UK', 'institution_ids': ['https://openalex.org/I28407311']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5041490168', 'display_name': 'Guanhua Yan', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I28407311', 'display_name': 'University of Manchester', 'ror': 'https://ror.org/027m9bs27', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I28407311']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Guanhua Yan', 'raw_affiliation_strings': ['Biological Sciences , Faculty of Biology, Medicine and Health , , The Michael Smith Building, Oxford Road, Manchester M13 9PT , UK', 'School ofBiological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, The Michael Smith Building, Oxford Road, Manchester M13 9PT, UK', 'University of Manchester , Faculty of Biology, Medicine and Health , , The Michael Smith Building, Oxford Road, Manchester M13 9PT , UK'], 'affiliations': [{'raw_affiliation_string': 'School ofBiological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, The Michael Smith Building, Oxford Road, Manchester M13 9PT, UK', 'institution_ids': ['https://openalex.org/I28407311']}, {'raw_affiliation_string': 'Biological Sciences , Faculty of Biology, Medicine and Health , , The Michael Smith Building, Oxford Road, Manchester M13 9PT , UK', 'institution_ids': []}, {'raw_affiliation_string': 'University of Manchester , Faculty of Biology, Medicine and Health , , The Michael Smith Building, Oxford Road, Manchester M13 9PT , UK', 'institution_ids': ['https://openalex.org/I28407311']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5010533721', 'display_name': 'Martin Lowe', 'orcid': 'https://orcid.org/0000-0002-9331-8143'}, 'institutions': [{'id': 'https://openalex.org/I28407311', 'display_name': 'University of Manchester', 'ror': 'https://ror.org/027m9bs27', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I28407311']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Martin Lowe', 'raw_affiliation_strings': ['Biological Sciences , Faculty of Biology, Medicine and Health , , The Michael Smith Building, Oxford Road, Manchester M13 9PT , UK', 'School ofBiological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, The Michael Smith Building, Oxford Road, Manchester M13 9PT, UK', 'University of Manchester , Faculty of Biology, Medicine and Health , , The Michael Smith Building, Oxford Road, Manchester M13 9PT , UK'], 'affiliations': [{'raw_affiliation_string': 'School ofBiological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, The Michael Smith Building, Oxford Road, Manchester M13 9PT, UK', 'institution_ids': ['https://openalex.org/I28407311']}, {'raw_affiliation_string': 'Biological Sciences , Faculty of Biology, Medicine and Health , , The Michael Smith Building, Oxford Road, Manchester M13 9PT , UK', 'institution_ids': []}, {'raw_affiliation_string': 'University of Manchester , Faculty of Biology, Medicine and Health , , The Michael Smith Building, Oxford Road, Manchester M13 9PT , UK', 'institution_ids': ['https://openalex.org/I28407311']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 1995, 'currency': 'USD', 'value_usd': 1995, 'provenance': 'doaj'}, 'apc_paid': {'value': 1995, 'currency': 'USD', 'value_usd': 1995, 'provenance': 'doaj'}, 'fwci': 0.128, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 1, 'citation_normalized_percentile': {'value': 0.351006, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 60, 'max': 70}, 'biblio': {'volume': '11', 'issue': '6', 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10691', 'display_name': 'Retinal Development and Disorders', 'score': 0.9975, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10691', 'display_name': 'Retinal Development and Disorders', 'score': 0.9975, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10617', 'display_name': 'Cellular transport and secretion', 'score': 0.9964, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11412', 'display_name': 'Genetic and Kidney Cyst Diseases', 'score': 0.9933, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/bulk-endocytosis', 'display_name': 'Bulk endocytosis', 'score': 0.45694762}, {'id': 'https://openalex.org/keywords/pronephros', 'display_name': 'Pronephros', 'score': 0.42971915}], 'concepts': [{'id': 'https://openalex.org/C28005876', 'wikidata': 'https://www.wikidata.org/wiki/Q189814', 'display_name': 'Endocytosis', 'level': 3, 'score': 0.97068}, {'id': 'https://openalex.org/C79747257', 'wikidata': 'https://www.wikidata.org/wiki/Q189814', 'display_name': 'Endocytic cycle', 'level': 4, 'score': 0.96592414}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.7715752}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.73502135}, {'id': 'https://openalex.org/C2776878037', 'wikidata': 'https://www.wikidata.org/wiki/Q169444', 'display_name': 'Zebrafish', 'level': 3, 'score': 0.62758684}, {'id': 'https://openalex.org/C117943116', 'wikidata': 'https://www.wikidata.org/wiki/Q1135604', 'display_name': 'Receptor-mediated endocytosis', 'level': 4, 'score': 0.50705504}, {'id': 'https://openalex.org/C191597335', 'wikidata': 'https://www.wikidata.org/wiki/Q4996475', 'display_name': 'Bulk endocytosis', 'level': 5, 'score': 0.45694762}, {'id': 'https://openalex.org/C31697123', 'wikidata': 'https://www.wikidata.org/wiki/Q2656768', 'display_name': 'Pronephros', 'level': 4, 'score': 0.42971915}, {'id': 'https://openalex.org/C28406088', 'wikidata': 'https://www.wikidata.org/wiki/Q5571762', 'display_name': 'Extracellular', 'level': 2, 'score': 0.41014266}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.29431164}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.17172116}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D026561', 'descriptor_name': 'Low Density Lipoprotein Receptor-Related Protein-2', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D015027', 'descriptor_name': 'Zebrafish', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001692', 'descriptor_name': 'Biological Transport', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004705', 'descriptor_name': 'Endocytosis', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D004705', 'descriptor_name': 'Endocytosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007687', 'descriptor_name': 'Kidney Tubules, Proximal', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D007687', 'descriptor_name': 'Kidney Tubules, Proximal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D026561', 'descriptor_name': 'Low Density Lipoprotein Receptor-Related Protein-2', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D026561', 'descriptor_name': 'Low Density Lipoprotein Receptor-Related Protein-2', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008322', 'descriptor_name': 'Mammals', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008322', 'descriptor_name': 'Mammals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015027', 'descriptor_name': 'Zebrafish', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1242/bio.059150', 'pdf_url': 'https://journals.biologists.com/bio/article-pdf/11/6/bio059150/2149505/bio059150.pdf', 'source': {'id': 'https://openalex.org/S2738063279', 'display_name': 'Biology Open', 'issn_l': '2046-6390', 'issn': ['2046-6390'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311847', 'host_organization_name': 'The Company of Biologists', 'host_organization_lineage': ['https://openalex.org/P4310311847'], 'host_organization_lineage_names': ['The Company of Biologists'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://doaj.org/article/1d8592447fcd421c9b71099286cca6e4', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306401280', 'display_name': 'DOAJ (DOAJ: Directory of Open Access Journals)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9235069', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/35616009', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1242/bio.059150', 'pdf_url': 'https://journals.biologists.com/bio/article-pdf/11/6/bio059150/2149505/bio059150.pdf', 'source': {'id': 'https://openalex.org/S2738063279', 'display_name': 'Biology Open', 'issn_l': '2046-6390', 'issn': ['2046-6390'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311847', 'host_organization_name': 'The Company of Biologists', 'host_organization_lineage': ['https://openalex.org/P4310311847'], 'host_organization_lineage_names': ['The Company of Biologists'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.51, 'id': 'https://metadata.un.org/sdg/14', 'display_name': 'Life below water'}], 'grants': [{'funder': 'https://openalex.org/F4320311904', 'funder_display_name': 'Wellcome Trust', 'award_id': '106505/Z/14/Z'}, {'funder': 'https://openalex.org/F4320311904', 'funder_display_name': 'Wellcome Trust', 'award_id': '203995/Z/16/Z'}, {'funder': 'https://openalex.org/F4320320291', 'funder_display_name': 'University of Manchester', 'award_id': None}], 'datasets': [], 'versions': [], 'referenced_works_count': 35, 'referenced_works': ['https://openalex.org/W1966231010', 'https://openalex.org/W1984849799', 'https://openalex.org/W1987946147', 'https://openalex.org/W1997018252', 'https://openalex.org/W2017641734', 'https://openalex.org/W2019751519', 'https://openalex.org/W2032989168', 'https://openalex.org/W2037257291', 'https://openalex.org/W2040509546', 'https://openalex.org/W2049315117', 'https://openalex.org/W2053610637', 'https://openalex.org/W2060650825', 'https://openalex.org/W2061870770', 'https://openalex.org/W2071588601', 'https://openalex.org/W2075986393', 'https://openalex.org/W2080418777', 'https://openalex.org/W2081849574', 'https://openalex.org/W2095137872', 'https://openalex.org/W2097421214', 'https://openalex.org/W2109208017', 'https://openalex.org/W2111448029', 'https://openalex.org/W2111650735', 'https://openalex.org/W2118920769', 'https://openalex.org/W2124387015', 'https://openalex.org/W2401547498', 'https://openalex.org/W2465492279', 'https://openalex.org/W2765322145', 'https://openalex.org/W2768201710', 'https://openalex.org/W2795687816', 'https://openalex.org/W2914663768', 'https://openalex.org/W2966359252', 'https://openalex.org/W3160094116', 'https://openalex.org/W3207709104', 'https://openalex.org/W3214152016', 'https://openalex.org/W4226335726'], 'related_works': ['https://openalex.org/W4214904210', 'https://openalex.org/W4206900932', 'https://openalex.org/W3154548854', 'https://openalex.org/W2883934207', 'https://openalex.org/W2113304473', 'https://openalex.org/W2107801352', 'https://openalex.org/W1990275914', 'https://openalex.org/W1981861833', 'https://openalex.org/W1696439153', 'https://openalex.org/W1515622122'], 'abstract_inverted_index': {'ABSTRACT': [0], 'Endocytosis': [1], 'mediates': [2], 'the': [3, 10, 20, 24, 40, 44, 55, 73, 80, 99, 111, 129, 139, 157], 'cellular': [4], 'uptake': [5, 171], 'of': [6, 34, 54, 84, 122, 141, 174], 'numerous': [7], 'molecules': [8], 'from': [9, 39], 'extracellular': [11], 'space': [12], 'and': [13, 28, 92, 143, 172], 'is': [14, 88, 108, 116, 133, 151], 'a': [15, 69, 136], 'fundamentally': [16], 'important': [17], 'process.': [18], 'In': [19, 64], 'renal': [21, 41, 81, 103], 'proximal': [22, 82, 130, 158], 'tubule,': [23, 131, 159], 'scavenger': [25], 'receptor': [26], 'megalin': [27, 48, 142], 'its': [29], 'co-receptor': [30], 'cubilin': [31], 'mediate': [32], 'endocytosis': [33, 49, 78, 127, 155], 'low': [35], 'molecular': [36], 'weight': [37], 'proteins': [38], 'filtrate.': [42], 'However,': [43], 'extent': [45], 'to': [46, 98, 118, 168], 'which': [47, 132], 'relies': [50], 'on': [51], 'different': [52], 'components': [53], 'trafficking': [56, 166], 'machinery': [57, 167], 'remains': [58], 'relatively': [59], 'poorly': [60], 'defined': [61], 'in': [62, 77, 79, 93, 125, 138, 156], 'vivo.': [63], 'this': [65], 'study,': [66], 'we': [67], 'identify': [68], 'functional': [70], 'requirement': [71], 'for': [72, 153], 'F-BAR': [74], 'protein': [75], 'pacsin2': [76, 107, 123, 150], 'tubule': [83], 'zebrafish': [85, 95], 'larvae.': [86], 'Pacsin2': [87], 'expressed': [89], 'throughout': [90], 'development': [91], 'all': [94], 'tissues,': [96], 'similar': [97], 'mammalian': [100], 'orthologue.': [101], 'Within': [102], 'tubular': [104], 'epithelial': [105], 'cells,': [106], 'enriched': [109], 'at': [110], 'apical': [112], 'pole': [113], 'where': [114, 160], 'it': [115, 161], 'localised': [117], 'endocytic': [119, 144, 170], 'structures.': [120], 'Loss': [121], 'results': [124, 147], 'reduced': [126], 'within': [128], 'accompanied': [134], 'by': [135], 'reduction': [137], 'abundance': [140], 'organelles.': [145], 'Our': [146], 'indicate': [148], 'that': [149], 'required': [152], 'efficient': [154], 'likely': [162], 'cooperates': [163], 'with': [164], 'other': [165], 'maintain': [169], 'recycling': [173], 'megalin.': [175]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W4281554008', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}], 'updated_date': '2024-12-14T02:08:31.978862', 'created_date': '2022-05-27'}