Title: Increase of Serum Growth Hormone Concentration following Thyrotropin-Releasing Hormone Injection in Patients with Acromegaly or Gigantism
Abstract: Effect of TRH administration on serum TSH and GH was studied in 9 normal subjects and 11 patients with acromegaly or gigantism. TRH provoked a prompt increase of serum TSH in normal subjects, whereas no appreciable change of serum GH was observed. Serum TSH responses to TRH were lower in most of the patients, but 8 out of the patients showed a remarkable increase of serum GH within 30 min after TRH injection. These results appear to indicate that specificity of TRH is not absolute in the functioning pituitary tumor secreting GH.
Publication Year: 1972
Publication Date: 1972-07-01
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
Access and Citation
Cited By Count: 269
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot