Publication Information

{'id': 'https://openalex.org/W2063882008', 'doi': 'https://doi.org/10.4161/cbt.8.1.7237', 'title': 'Pediatric low-grade gliomas and the need for new options for therapy: why and how?', 'display_name': 'Pediatric low-grade gliomas and the need for new options for therapy: why and how?', 'publication_year': 2009, 'publication_date': '2009-01-01', 'ids': {'openalex': 'https://openalex.org/W2063882008', 'doi': 'https://doi.org/10.4161/cbt.8.1.7237', 'mag': '2063882008', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/19164945', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/2810626'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.4161/cbt.8.1.7237', 'pdf_url': 'https://www.tandfonline.com/doi/pdf/10.4161/cbt.8.1.7237?needAccess=true&role=button', 'source': {'id': 'https://openalex.org/S169029442', 'display_name': 'Cancer Biology & Therapy', 'issn_l': '1538-4047', 'issn': ['1538-4047', '1555-8576'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320547', 'host_organization_name': 'Taylor & Francis', 'host_organization_lineage': ['https://openalex.org/P4310320547'], 'host_organization_lineage_names': ['Taylor & Francis'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://www.tandfonline.com/doi/pdf/10.4161/cbt.8.1.7237?needAccess=true&role=button', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5059921916', 'display_name': 'Ibrahim Qaddoumi', 'orcid': 'https://orcid.org/0000-0002-6645-4895'}, 'institutions': [{'id': 'https://openalex.org/I1313298211', 'display_name': "St. Jude Children's Research Hospital", 'ror': 'https://ror.org/02r3e0967', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1313298211', 'https://openalex.org/I2802152183']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Ibrahim Qaddoumi', 'raw_affiliation_strings': ["Department of Oncology, St. Jude Children's Research Hospital, Memphis,Tennessee, USA."], 'affiliations': [{'raw_affiliation_string': "Department of Oncology, St. Jude Children's Research Hospital, Memphis,Tennessee, USA.", 'institution_ids': ['https://openalex.org/I1313298211']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5015683038', 'display_name': 'Iyad Sultan', 'orcid': 'https://orcid.org/0000-0002-2664-1565'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Iyad Sultan', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5024114730', 'display_name': 'Alberto Broniscer', 'orcid': 'https://orcid.org/0000-0001-9646-0463'}, 'institutions': [{'id': 'https://openalex.org/I1313298211', 'display_name': "St. Jude Children's Research Hospital", 'ror': 'https://ror.org/02r3e0967', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1313298211', 'https://openalex.org/I2802152183']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Alberto Broniscer', 'raw_affiliation_strings': ['St. Jude Children Research Hospital'], 'affiliations': [{'raw_affiliation_string': 'St. Jude Children Research Hospital', 'institution_ids': ['https://openalex.org/I1313298211']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 2710, 'currency': 'EUR', 'value_usd': 2970, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.905, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 55, 'citation_normalized_percentile': {'value': 0.791489, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 94, 'max': 95}, 'biblio': {'volume': '8', 'issue': '1', 'first_page': '4', 'last_page': '10'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11173', 'display_name': 'Neurofibromatosis and Schwannoma Cases', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2728', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11173', 'display_name': 'Neurofibromatosis and Schwannoma Cases', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2728', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10129', 'display_name': 'Glioma Diagnosis and Treatment', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/2716', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12226', 'display_name': 'Neuroblastoma Research and Treatments', 'score': 0.9944, 'subfield': {'id': 'https://openalex.org/subfields/2728', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/pilocytic-astrocytoma', 'display_name': 'Pilocytic astrocytoma', 'score': 0.97114885}], 'concepts': [{'id': 'https://openalex.org/C2777722931', 'wikidata': 'https://www.wikidata.org/wiki/Q2095252', 'display_name': 'Pilocytic astrocytoma', 'level': 4, 'score': 0.97114885}, {'id': 'https://openalex.org/C2778984943', 'wikidata': 'https://www.wikidata.org/wiki/Q847605', 'display_name': 'Neurofibromatosis', 'level': 2, 'score': 0.80096006}, {'id': 'https://openalex.org/C2778880634', 'wikidata': 'https://www.wikidata.org/wiki/Q177755', 'display_name': 'Astrocytoma', 'level': 3, 'score': 0.79064095}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.6329072}, {'id': 'https://openalex.org/C2778227246', 'wikidata': 'https://www.wikidata.org/wiki/Q1365309', 'display_name': 'Glioma', 'level': 2, 'score': 0.62464935}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.4311973}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.3752089}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.18730724}], 'mesh': [{'descriptor_ui': 'D001932', 'descriptor_name': 'Brain Neoplasms', 'qualifier_ui': 'Q000628', 'qualifier_name': 'therapy', 'is_major_topic': True}, {'descriptor_ui': 'D005910', 'descriptor_name': 'Glioma', 'qualifier_ui': 'Q000628', 'qualifier_name': 'therapy', 'is_major_topic': True}, {'descriptor_ui': 'D001932', 'descriptor_name': 'Brain Neoplasms', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D001932', 'descriptor_name': 'Brain Neoplasms', 'qualifier_ui': 'Q000453', 'qualifier_name': 'epidemiology', 'is_major_topic': False}, {'descriptor_ui': 'D001932', 'descriptor_name': 'Brain Neoplasms', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D001932', 'descriptor_name': 'Brain Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002648', 'descriptor_name': 'Child', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002897', 'descriptor_name': 'Chromosomes, Human, Pair 7', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017353', 'descriptor_name': 'Gene Deletion', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015316', 'descriptor_name': 'Genetic Therapy', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': False}, {'descriptor_ui': 'D015316', 'descriptor_name': 'Genetic Therapy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005910', 'descriptor_name': 'Glioma', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D005910', 'descriptor_name': 'Glioma', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D005910', 'descriptor_name': 'Glioma', 'qualifier_ui': 'Q000453', 'qualifier_name': 'epidemiology', 'is_major_topic': False}, {'descriptor_ui': 'D005910', 'descriptor_name': 'Glioma', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009456', 'descriptor_name': 'Neurofibromatosis 1', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D009456', 'descriptor_name': 'Neurofibromatosis 1', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D048493', 'descriptor_name': 'Proto-Oncogene Proteins B-raf', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D048493', 'descriptor_name': 'Proto-Oncogene Proteins B-raf', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.4161/cbt.8.1.7237', 'pdf_url': 'https://www.tandfonline.com/doi/pdf/10.4161/cbt.8.1.7237?needAccess=true&role=button', 'source': {'id': 'https://openalex.org/S169029442', 'display_name': 'Cancer Biology & Therapy', 'issn_l': '1538-4047', 'issn': ['1538-4047', '1555-8576'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320547', 'host_organization_name': 'Taylor & Francis', 'host_organization_lineage': ['https://openalex.org/P4310320547'], 'host_organization_lineage_names': ['Taylor & Francis'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc2810626', 'pdf_url': 'https://europepmc.org/articles/pmc2810626?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810626', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/19164945', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.4161/cbt.8.1.7237', 'pdf_url': 'https://www.tandfonline.com/doi/pdf/10.4161/cbt.8.1.7237?needAccess=true&role=button', 'source': {'id': 'https://openalex.org/S169029442', 'display_name': 'Cancer Biology & Therapy', 'issn_l': '1538-4047', 'issn': ['1538-4047', '1555-8576'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320547', 'host_organization_name': 'Taylor & Francis', 'host_organization_lineage': ['https://openalex.org/P4310320547'], 'host_organization_lineage_names': ['Taylor & Francis'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 95, 'referenced_works': ['https://openalex.org/W1548705231', 'https://openalex.org/W1557727281', 'https://openalex.org/W1571401370', 'https://openalex.org/W1961018259', 'https://openalex.org/W1964601937', 'https://openalex.org/W1969441567', 'https://openalex.org/W1969981749', 'https://openalex.org/W1970574581', 'https://openalex.org/W1973164955', 'https://openalex.org/W1983493537', 'https://openalex.org/W1986530870', 'https://openalex.org/W1988345639', 'https://openalex.org/W1994502045', 'https://openalex.org/W1995607634', 'https://openalex.org/W2003391946', 'https://openalex.org/W2007194256', 'https://openalex.org/W2012696125', 'https://openalex.org/W2015396002', 'https://openalex.org/W2016113597', 'https://openalex.org/W2016318689', 'https://openalex.org/W2016997594', 'https://openalex.org/W2021447976', 'https://openalex.org/W2022853153', 'https://openalex.org/W2023952478', 'https://openalex.org/W2029628307', 'https://openalex.org/W2032555040', 'https://openalex.org/W2033432342', 'https://openalex.org/W2035665330', 'https://openalex.org/W2036450767', 'https://openalex.org/W2037538572', 'https://openalex.org/W2039382551', 'https://openalex.org/W2044203557', 'https://openalex.org/W2044282514', 'https://openalex.org/W2046077995', 'https://openalex.org/W2047319598', 'https://openalex.org/W2047347511', 'https://openalex.org/W2047902204', 'https://openalex.org/W2049171090', 'https://openalex.org/W2049594738', 'https://openalex.org/W2054027679', 'https://openalex.org/W2061655178', 'https://openalex.org/W2062008417', 'https://openalex.org/W2062809578', 'https://openalex.org/W2065189305', 'https://openalex.org/W2066441128', 'https://openalex.org/W2067034998', 'https://openalex.org/W2069471645', 'https://openalex.org/W2070068984', 'https://openalex.org/W2072545333', 'https://openalex.org/W2072549970', 'https://openalex.org/W2073302657', 'https://openalex.org/W2076290120', 'https://openalex.org/W2076588816', 'https://openalex.org/W2079895796', 'https://openalex.org/W2081961106', 'https://openalex.org/W2084014883', 'https://openalex.org/W2088339166', 'https://openalex.org/W2089632625', 'https://openalex.org/W2089906643', 'https://openalex.org/W2092467531', 'https://openalex.org/W2093130407', 'https://openalex.org/W2093548930', 'https://openalex.org/W2094224485', 'https://openalex.org/W2094447223', 'https://openalex.org/W2099938621', 'https://openalex.org/W2101844404', 'https://openalex.org/W2103040128', 'https://openalex.org/W2109467838', 'https://openalex.org/W2118119833', 'https://openalex.org/W2120667391', 'https://openalex.org/W2122340058', 'https://openalex.org/W2123953071', 'https://openalex.org/W2124187900', 'https://openalex.org/W2126595521', 'https://openalex.org/W2129400742', 'https://openalex.org/W2129882467', 'https://openalex.org/W2130504509', 'https://openalex.org/W2138319766', 'https://openalex.org/W2141527930', 'https://openalex.org/W2148504560', 'https://openalex.org/W2152165396', 'https://openalex.org/W2157178968', 'https://openalex.org/W2157618479', 'https://openalex.org/W2159096148', 'https://openalex.org/W2159099714', 'https://openalex.org/W2162761143', 'https://openalex.org/W2167453812', 'https://openalex.org/W2319887569', 'https://openalex.org/W2323317437', 'https://openalex.org/W232718294', 'https://openalex.org/W2329376561', 'https://openalex.org/W2396746017', 'https://openalex.org/W2409697503', 'https://openalex.org/W2900724563', 'https://openalex.org/W36312574'], 'related_works': ['https://openalex.org/W4236461076', 'https://openalex.org/W3217537326', 'https://openalex.org/W2223437299', 'https://openalex.org/W2151805770', 'https://openalex.org/W2120343071', 'https://openalex.org/W2097698716', 'https://openalex.org/W2063882008', 'https://openalex.org/W2062008417', 'https://openalex.org/W2058349469', 'https://openalex.org/W14064154'], 'abstract_inverted_index': {'AbstractPediatric': [0], 'low-grade': [1, 39, 68, 129], 'gliomas': [2, 40, 69], 'are': [3, 25, 70], 'the': [4, 9, 64, 103], 'most': [5, 74], 'common': [6], 'tumors': [7, 30, 77], 'of': [8, 19, 29, 47, 58, 60, 84, 127], 'central': [10], 'nervous': [11], 'system': [12], 'in': [13, 89, 99, 114], 'children,': [14], 'accounting': [15], 'for': [16, 105], 'almost': [17], '50%': [18], 'all': [20], 'childhood': [21], 'brain': [22], 'tumors.': [23], 'They': [24], 'a': [26, 42, 56], 'heterogeneous': [27], 'group': [28], 'with': [31], 'different': [32], 'histologic': [33, 125], 'subtypes.': [34], 'Most': [35], 'treatment': [36, 49], 'studies': [37], 'address': [38], 'as': [41], 'single': [43], 'entity,': [44], 'depriving': [45], 'us': [46], 'histology-specific': [48], 'outcomes.': [50], 'This': [51], 'is': [52], 'mostly': [53], 'due': [54], 'to': [55, 118, 123], 'lack': [57], 'understanding': [59, 90], 'tumor': [61], 'biology': [62], 'at': [63], 'molecular': [65], 'level.': [66], 'Pediatric': [67], 'not': [71], 'benign,': [72], 'and': [73, 80, 94, 109, 121], 'incompletely': [75], 'resected': [76], 'will': [78], 'progress': [79, 113], 'negatively': [81], 'affect': [82], 'quality': [83], 'life.': [85], 'The': [86], 'advancements': [87], 'made': [88], 'sporadic': [91], 'pilocytic': [92, 97, 115], 'astrocytoma': [93, 98, 116], 'neurofibromatosis': [95], '1-associated': [96], 'particular': [100], 'have': [101], 'paved': [102], 'way': [104], 'potential': [106], 'targeted': [107], 'therapy': [108], 'biological': [110], 'stratification.': [111], 'Such': [112], 'needs': [117], 'be': [119], 'consolidated': [120], 'expanded': [122], 'other': [124], 'varieties': [126], 'pediatric': [128], 'gliomas.': [130]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2063882008', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 3}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 3}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 4}, {'year': 2016, 'cited_by_count': 7}, {'year': 2015, 'cited_by_count': 5}, {'year': 2014, 'cited_by_count': 3}, {'year': 2013, 'cited_by_count': 8}, {'year': 2012, 'cited_by_count': 8}], 'updated_date': '2025-01-12T05:12:52.841467', 'created_date': '2016-06-24'}