Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2061928622', 'doi': 'https://doi.org/10.2353/ajpath.2010.100328', 'title': 'The Transcription Factor MIST1 Is a Novel Human Gastric Chief Cell Marker Whose Expression Is Lost in Metaplasia, Dysplasia, and Carcinoma', 'display_name': 'The Transcription Factor MIST1 Is a Novel Human Gastric Chief Cell Marker Whose Expression Is Lost in Metaplasia, Dysplasia, and Carcinoma', 'publication_year': 2010, 'publication_date': '2010-09-01', 'ids': {'openalex': 'https://openalex.org/W2061928622', 'doi': 'https://doi.org/10.2353/ajpath.2010.100328', 'mag': '2061928622', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/20709804', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/2928982'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.2353/ajpath.2010.100328', 'pdf_url': 'http://ajp.amjpathol.org/article/S0002944010602039/pdf', 'source': {'id': 'https://openalex.org/S145577119', 'display_name': 'American Journal Of Pathology', 'issn_l': '0002-9440', 'issn': ['0002-9440', '1525-2191'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'publisher-specific-oa', 'license_id': 'https://openalex.org/licenses/publisher-specific-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'http://ajp.amjpathol.org/article/S0002944010602039/pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5067299042', 'display_name': 'Jochen K. Lennerz', 'orcid': 'https://orcid.org/0000-0003-2434-4978'}, 'institutions': [{'id': 'https://openalex.org/I204465549', 'display_name': 'Washington University in St. Louis', 'ror': 'https://ror.org/01yc7t268', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I204465549']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Jochen K M Lennerz', 'raw_affiliation_strings': ['Department of Pathology and Immunology, Washington University School of Medicine, Louis, MO 63110, USA.'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology and Immunology, Washington University School of Medicine, Louis, MO 63110, USA.', 'institution_ids': ['https://openalex.org/I204465549']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5057695550', 'display_name': 'Seok-Hyung Kim', 'orcid': 'https://orcid.org/0009-0002-1333-3720'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Seok-Hyung Kim', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5050627843', 'display_name': 'Edward Oates', 'orcid': 'https://orcid.org/0000-0002-0894-9507'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Edward L Oates', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5055026680', 'display_name': 'Won Jae Huh', 'orcid': 'https://orcid.org/0000-0002-6695-5753'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Won Jae Huh', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5070232292', 'display_name': 'Jason Doherty', 'orcid': 'https://orcid.org/0000-0003-3142-5805'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Jason M Doherty', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101874881', 'display_name': 'Xiaolin Tian', 'orcid': 'https://orcid.org/0000-0003-2397-8151'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Xiaolin Tian', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5017514251', 'display_name': 'Andrew J. Bredemeyer', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Andrew J Bredemeyer', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5010236925', 'display_name': 'James R. Goldenring', 'orcid': 'https://orcid.org/0000-0002-7833-2940'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'James R Goldenring', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5035763230', 'display_name': 'Gregory Y. Lauwers', 'orcid': 'https://orcid.org/0000-0002-0897-5385'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Gregory Y Lauwers', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5002243126', 'display_name': 'Young Kee Shin', 'orcid': 'https://orcid.org/0000-0003-0896-718X'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Young-Kee Shin', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5086932115', 'display_name': 'Jason C. Mills', 'orcid': 'https://orcid.org/0000-0002-0402-4662'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Jason C Mills', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 2800, 'currency': 'USD', 'value_usd': 2800, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 8.104, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 108, 'citation_normalized_percentile': {'value': 0.999979, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '177', 'issue': '3', 'first_page': '1514', 'last_page': '1533'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10276', 'display_name': 'Helicobacter pylori Infection and Gastric Cancer', 'score': 0.9943, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10276', 'display_name': 'Helicobacter pylori Infection and Gastric Cancer', 'score': 0.9943, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T13199', 'display_name': 'Genetic Adaptation of Lactase Persistence in Humans', 'score': 0.9875, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T13157', 'display_name': 'Protein Arginine Methylation in Mammals', 'score': 0.9675, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/metaplasia', 'display_name': 'Metaplasia', 'score': 0.61861485}, {'id': 'https://openalex.org/keywords/intestinal-metaplasia', 'display_name': 'Intestinal metaplasia', 'score': 0.52713513}, {'id': 'https://openalex.org/keywords/gastric-metaplasia', 'display_name': 'Gastric Metaplasia', 'score': 0.52325}], 'concepts': [{'id': 'https://openalex.org/C2775894508', 'wikidata': 'https://www.wikidata.org/wiki/Q1128996', 'display_name': 'Dysplasia', 'level': 2, 'score': 0.6945487}, {'id': 'https://openalex.org/C86339819', 'wikidata': 'https://www.wikidata.org/wiki/Q407384', 'display_name': 'Transcription factor', 'level': 3, 'score': 0.6475142}, {'id': 'https://openalex.org/C2779357193', 'wikidata': 'https://www.wikidata.org/wiki/Q660713', 'display_name': 'Metaplasia', 'level': 2, 'score': 0.61861485}, {'id': 'https://openalex.org/C2776497702', 'wikidata': 'https://www.wikidata.org/wiki/Q872095', 'display_name': 'Intestinal metaplasia', 'level': 3, 'score': 0.52713513}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.3879876}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.3809861}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.3543975}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.29941338}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.22055158}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.17154789}], 'mesh': [{'descriptor_ui': 'D048868', 'descriptor_name': 'Adaptor Proteins, Signal Transducing', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D019872', 'descriptor_name': 'Chief Cells, Gastric', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D005767', 'descriptor_name': 'Gastrointestinal Diseases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D041981', 'descriptor_name': 'Gastrointestinal Tract', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D048868', 'descriptor_name': 'Adaptor Proteins, Signal Transducing', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D048868', 'descriptor_name': 'Adaptor Proteins, Signal Transducing', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015153', 'descriptor_name': 'Blotting, Western', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002478', 'descriptor_name': 'Cells, Cultured', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019872', 'descriptor_name': 'Chief Cells, Gastric', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D019872', 'descriptor_name': 'Chief Cells, Gastric', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005753', 'descriptor_name': 'Gastric Mucosa', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D005753', 'descriptor_name': 'Gastric Mucosa', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D005753', 'descriptor_name': 'Gastric Mucosa', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005767', 'descriptor_name': 'Gastrointestinal Diseases', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D005767', 'descriptor_name': 'Gastrointestinal Diseases', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D005767', 'descriptor_name': 'Gastrointestinal Diseases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D041981', 'descriptor_name': 'Gastrointestinal Tract', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D041981', 'descriptor_name': 'Gastrointestinal Tract', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007150', 'descriptor_name': 'Immunohistochemistry', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008679', 'descriptor_name': 'Metaplasia', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008679', 'descriptor_name': 'Metaplasia', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D008679', 'descriptor_name': 'Metaplasia', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008679', 'descriptor_name': 'Metaplasia', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D018613', 'descriptor_name': 'Microscopy, Confocal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D046888', 'descriptor_name': 'Tissue Array Analysis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000071164', 'descriptor_name': 'Trefoil Factor-2', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.2353/ajpath.2010.100328', 'pdf_url': 'http://ajp.amjpathol.org/article/S0002944010602039/pdf', 'source': {'id': 'https://openalex.org/S145577119', 'display_name': 'American Journal Of Pathology', 'issn_l': '0002-9440', 'issn': ['0002-9440', '1525-2191'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'publisher-specific-oa', 'license_id': 'https://openalex.org/licenses/publisher-specific-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc2928982', 'pdf_url': 'https://europepmc.org/articles/pmc2928982?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928982', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/20709804', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.2353/ajpath.2010.100328', 'pdf_url': 'http://ajp.amjpathol.org/article/S0002944010602039/pdf', 'source': {'id': 'https://openalex.org/S145577119', 'display_name': 'American Journal Of Pathology', 'issn_l': '0002-9440', 'issn': ['0002-9440', '1525-2191'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'publisher-specific-oa', 'license_id': 'https://openalex.org/licenses/publisher-specific-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.65, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [{'funder': 'https://openalex.org/F4320306127', 'funder_display_name': 'U.S. Department of Veterans Affairs', 'award_id': '30 DK52574'}, {'funder': 'https://openalex.org/F4320306127', 'funder_display_name': 'U.S. Department of Veterans Affairs', 'award_id': 'RO1 DK071590'}], 'datasets': [], 'versions': [], 'referenced_works_count': 121, 'referenced_works': ['https://openalex.org/W1498874189', 'https://openalex.org/W1512371595', 'https://openalex.org/W1518192013', 'https://openalex.org/W1530072545', 'https://openalex.org/W1544915528', 'https://openalex.org/W1830830895', 'https://openalex.org/W1893036907', 'https://openalex.org/W1906697283', 'https://openalex.org/W1966750940', 'https://openalex.org/W1968149100', 'https://openalex.org/W1968765201', 'https://openalex.org/W1968857947', 'https://openalex.org/W1974042556', 'https://openalex.org/W1974304041', 'https://openalex.org/W1975369642', 'https://openalex.org/W1976671493', 'https://openalex.org/W1979287862', 'https://openalex.org/W1983187929', 'https://openalex.org/W1985261214', 'https://openalex.org/W1987666378', 'https://openalex.org/W1988046416', 'https://openalex.org/W1989623206', 'https://openalex.org/W1996739849', 'https://openalex.org/W1997451299', 'https://openalex.org/W1999071717', 'https://openalex.org/W2004192085', 'https://openalex.org/W2006464570', 'https://openalex.org/W2006711580', 'https://openalex.org/W2008667208', 'https://openalex.org/W2015174770', 'https://openalex.org/W2016207291', 'https://openalex.org/W2017831003', 'https://openalex.org/W2020830322', 'https://openalex.org/W2023684186', 'https://openalex.org/W2024403987', 'https://openalex.org/W2027366995', 'https://openalex.org/W2029080419', 'https://openalex.org/W2029423613', 'https://openalex.org/W2031849083', 'https://openalex.org/W2032205189', 'https://openalex.org/W2032671681', 'https://openalex.org/W2035037115', 'https://openalex.org/W2038404321', 'https://openalex.org/W2039087946', 'https://openalex.org/W2043748755', 'https://openalex.org/W2044138444', 'https://openalex.org/W2044408791', 'https://openalex.org/W2046951924', 'https://openalex.org/W2047122899', 'https://openalex.org/W2048030072', 'https://openalex.org/W2049180434', 'https://openalex.org/W2053154970', 'https://openalex.org/W2055528975', 'https://openalex.org/W2060298161', 'https://openalex.org/W2060804205', 'https://openalex.org/W2061139841', 'https://openalex.org/W2062447494', 'https://openalex.org/W2063327523', 'https://openalex.org/W2065031087', 'https://openalex.org/W2065121957', 'https://openalex.org/W2067438558', 'https://openalex.org/W2073809314', 'https://openalex.org/W2076430260', 'https://openalex.org/W2078134864', 'https://openalex.org/W2079524461', 'https://openalex.org/W2080851462', 'https://openalex.org/W2083637425', 'https://openalex.org/W2085904237', 'https://openalex.org/W2090241102', 'https://openalex.org/W2091155196', 'https://openalex.org/W2091941130', 'https://openalex.org/W2093007002', 'https://openalex.org/W2093590019', 'https://openalex.org/W2094064713', 'https://openalex.org/W2094996977', 'https://openalex.org/W2096853390', 'https://openalex.org/W2096888542', 'https://openalex.org/W2096969440', 'https://openalex.org/W2097387056', 'https://openalex.org/W2097921155', 'https://openalex.org/W2102778060', 'https://openalex.org/W2106246537', 'https://openalex.org/W2106787323', 'https://openalex.org/W2109189178', 'https://openalex.org/W2111432243', 'https://openalex.org/W2114278038', 'https://openalex.org/W2116100337', 'https://openalex.org/W2116849106', 'https://openalex.org/W2119390568', 'https://openalex.org/W2119520453', 'https://openalex.org/W2123155461', 'https://openalex.org/W2125802717', 'https://openalex.org/W2127258120', 'https://openalex.org/W2127539716', 'https://openalex.org/W2132657404', 'https://openalex.org/W2138538113', 'https://openalex.org/W2141428099', 'https://openalex.org/W2143107875', 'https://openalex.org/W2147705631', 'https://openalex.org/W2148553058', 'https://openalex.org/W2150760649', 'https://openalex.org/W2152314991', 'https://openalex.org/W2153600956', 'https://openalex.org/W2156566257', 'https://openalex.org/W2160504871', 'https://openalex.org/W2163744142', 'https://openalex.org/W2164348684', 'https://openalex.org/W2165699663', 'https://openalex.org/W2410271523', 'https://openalex.org/W2419381115', 'https://openalex.org/W2948387191', 'https://openalex.org/W4230516657', 'https://openalex.org/W4233621387', 'https://openalex.org/W4240547861', 'https://openalex.org/W4244330657', 'https://openalex.org/W4247792890', 'https://openalex.org/W4285719527', 'https://openalex.org/W4297724330', 'https://openalex.org/W4322701881', 'https://openalex.org/W624674342', 'https://openalex.org/W62874699'], 'related_works': ['https://openalex.org/W4233262103', 'https://openalex.org/W2970714593', 'https://openalex.org/W2621353671', 'https://openalex.org/W2581797878', 'https://openalex.org/W2386230622', 'https://openalex.org/W2375099654', 'https://openalex.org/W2179342495', 'https://openalex.org/W2146889894', 'https://openalex.org/W2018094305', 'https://openalex.org/W1999901487'], 'abstract_inverted_index': {'The': [0], 'lack': [1], 'of': [2, 13, 44, 75, 107, 115, 128, 145, 148, 177, 183, 199], 'reliable': [3, 197], 'molecular': [4], 'markers': [5], 'for': [6, 20], 'normal': [7, 162], 'differentiated': [8], 'epithelial': [9], 'cells': [10, 60], 'limits': [11], 'understanding': [12], 'human': [14, 76, 87], 'gastric': [15, 21, 149], 'carcinogenesis.': [16], 'Recognized': [17], 'precursor': [18], 'lesions': [19, 88], 'adenocarcinoma': [22], 'are': [23], 'intestinal': [24], 'metaplasia': [25, 30, 122, 211], 'and': [26, 37, 81, 100, 109, 126, 135, 170, 175, 204], 'spasmolytic': [27], 'polypeptide': [28], 'expressing': [29], '(SPEM),': [31], 'defined': [32], 'here': [33], 'by': [34], 'ectopic': [35], 'CDX2': [36, 110], 'TFF2': [38], 'expression,': [39], 'respectively.': [40], 'In': [41], 'mice,': [42], 'expression': [43, 69, 153], 'the': [45, 142, 157, 181, 207, 220], 'bHLH': [46], 'transcription': [47], 'factor': [48], 'MIST1,': [49, 83], 'normally': [50], 'restricted': [51, 155], 'to': [52, 91, 156], 'mature': [53], 'chief': [54, 59, 77, 158, 185, 202, 221], 'cells,': [55, 203], 'is': [56, 70, 84, 154], 'down-regulated': [57], 'as': [58, 195], 'undergo': [61], 'experimentally': [62], 'induced': [63], 'metaplasia.': [64], 'Here,': [65], 'we': [66, 205], 'show': [67], 'MIST1': [68, 108, 116, 152, 194], 'also': [71], 'a': [72, 118, 196], 'specific': [73], 'marker': [74, 198], 'cells.': [78], 'SPEM,': [79], 'with': [80, 117, 180], 'without': [82], 'present': [85], 'in': [86, 130, 161, 166, 172, 212, 217], 'and,': [89], 'akin': [90], 'murine': [92], 'data,': [93], 'likely': [94], 'represents': [95], 'transitional': [96], '(TFF2(+)/MIST1(+)': [97], '=': [98, 103], '"hybrid"-SPEM)': [99], 'established': [101, 167], '(TFF2(+)/MIST1(-)': [102], 'SPEM)': [104], 'stages.': [105], 'Co-visualization': [106], 'shows': [111], 'similar': [112], 'progressive': [113], 'loss': [114], 'transitional,': [119], 'CDX2(+)/MIST1(-)': [120], 'hybrid-intestinal': [121], 'stage.': [123], 'Interinstitutional': [124], 'analysis': [125], 'comparison': [127], 'findings': [129, 192], 'tissue': [131], 'microarrays,': [132], 'resection': [133], 'specimens,': [134], 'biopsies': [136], '(n': [137], '>': [138], '400': [139], 'samples),': [140], 'comprising': [141], 'entire': [143], 'spectrum': [144], 'recognized': [146], 'stages': [147], 'carcinogenesis,': [150], 'confirm': [151], 'cell': [159, 186, 222], 'compartment': [160], 'oxyntic': [163], 'mucosa,': [164], 'rare': [165, 184], 'metaplastic': [168], 'lesions,': [169], 'lost': [171], 'intraepithelial': [173], 'neoplasia/dysplasia': [174], 'carcinoma': [176, 187], 'various': [178], 'types': [179], 'exception': [182], '(': [188], 'approximately': [189], '1%).': [190], 'Our': [191], 'implicate': [193], 'mature,': [200], 'healthy': [201], 'provide': [206], 'first': [208], 'evidence': [209], 'that': [210], 'humans': [213], 'arises': [214], 'at': [215], 'least': [216], 'part': [218], 'from': [219], 'lineage.': [223]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2061928622', 'counts_by_year': [{'year': 2024, 'cited_by_count': 4}, {'year': 2023, 'cited_by_count': 10}, {'year': 2022, 'cited_by_count': 9}, {'year': 2021, 'cited_by_count': 7}, {'year': 2020, 'cited_by_count': 12}, {'year': 2019, 'cited_by_count': 11}, {'year': 2018, 'cited_by_count': 9}, {'year': 2017, 'cited_by_count': 8}, {'year': 2016, 'cited_by_count': 5}, {'year': 2015, 'cited_by_count': 5}, {'year': 2014, 'cited_by_count': 4}, {'year': 2013, 'cited_by_count': 12}, {'year': 2012, 'cited_by_count': 8}], 'updated_date': '2024-09-16T13:34:58.909846', 'created_date': '2016-06-24'}