Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2059555945', 'doi': 'https://doi.org/10.1016/0092-8674(94)90544-4', 'title': 'H2O2 from the oxidative burst orchestrates the plant hypersensitive disease resistance response', 'display_name': 'H2O2 from the oxidative burst orchestrates the plant hypersensitive disease resistance response', 'publication_year': 1994, 'publication_date': '1994-11-01', 'ids': {'openalex': 'https://openalex.org/W2059555945', 'doi': 'https://doi.org/10.1016/0092-8674(94)90544-4', 'mag': '2059555945', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/7954825'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/0092-8674(94)90544-4', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S110447773', 'display_name': 'Cell', 'issn_l': '0092-8674', 'issn': ['0092-8674', '1097-4172'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315673', 'host_organization_name': 'Cell Press', 'host_organization_lineage': ['https://openalex.org/P4310320990', 'https://openalex.org/P4310315673'], 'host_organization_lineage_names': ['Elsevier BV', 'Cell Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5054116833', 'display_name': 'Alex J. Levine', 'orcid': 'https://orcid.org/0000-0003-0780-1305'}, 'institutions': [{'id': 'https://openalex.org/I1307098950', 'display_name': 'Salk Institute for Biological Studies', 'ror': 'https://ror.org/03xez1567', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1307098950']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Alex Levine', 'raw_affiliation_strings': ['Plant Biology Laboratory The Salk Institute La Jolla, California 92037, USA'], 'affiliations': [{'raw_affiliation_string': 'Plant Biology Laboratory The Salk Institute La Jolla, California 92037, USA', 'institution_ids': ['https://openalex.org/I1307098950']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5067216022', 'display_name': 'Raimund Tenhaken', 'orcid': 'https://orcid.org/0000-0002-6764-4826'}, 'institutions': [{'id': 'https://openalex.org/I1307098950', 'display_name': 'Salk Institute for Biological Studies', 'ror': 'https://ror.org/03xez1567', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1307098950']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Raimund Tenhaken', 'raw_affiliation_strings': ['Plant Biology Laboratory The Salk Institute La Jolla, California 92037, USA'], 'affiliations': [{'raw_affiliation_string': 'Plant Biology Laboratory The Salk Institute La Jolla, California 92037, USA', 'institution_ids': ['https://openalex.org/I1307098950']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5047292984', 'display_name': 'Richard A. Dixon', 'orcid': 'https://orcid.org/0000-0001-8393-9408'}, 'institutions': [{'id': 'https://openalex.org/I4210126540', 'display_name': 'Noble Research Institute', 'ror': 'https://ror.org/02zta5505', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210126540']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Richard Dixon', 'raw_affiliation_strings': ['Plant Biology Division The Noble Foundation Ardmore, Oklahoma 73402, USA'], 'affiliations': [{'raw_affiliation_string': 'Plant Biology Division The Noble Foundation Ardmore, Oklahoma 73402, USA', 'institution_ids': ['https://openalex.org/I4210126540']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5079312266', 'display_name': 'Chris Lamb', 'orcid': 'https://orcid.org/0000-0002-4920-5918'}, 'institutions': [{'id': 'https://openalex.org/I1307098950', 'display_name': 'Salk Institute for Biological Studies', 'ror': 'https://ror.org/03xez1567', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1307098950']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Chris Lamb', 'raw_affiliation_strings': ['Plant Biology Laboratory The Salk Institute La Jolla, California 92037, USA'], 'affiliations': [{'raw_affiliation_string': 'Plant Biology Laboratory The Salk Institute La Jolla, California 92037, USA', 'institution_ids': ['https://openalex.org/I1307098950']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 10100, 'currency': 'USD', 'value_usd': 10100, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 126.764, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 2737, 'citation_normalized_percentile': {'value': 0.988432, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '79', 'issue': '4', 'first_page': '583', 'last_page': '593'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10076', 'display_name': 'Mechanisms of Plant Immune Response', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/1110', 'display_name': 'Plant Science'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10076', 'display_name': 'Mechanisms of Plant Immune Response', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/1110', 'display_name': 'Plant Science'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10014', 'display_name': 'Molecular Responses to Abiotic Stress in Plants', 'score': 0.9965, 'subfield': {'id': 'https://openalex.org/subfields/1110', 'display_name': 'Plant Science'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10494', 'display_name': 'Viral RNA Silencing and Plant Immunity', 'score': 0.9964, 'subfield': {'id': 'https://openalex.org/subfields/1110', 'display_name': 'Plant Science'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/respiratory-burst', 'display_name': 'Respiratory burst', 'score': 0.80107737}, {'id': 'https://openalex.org/keywords/hypersensitive-response', 'display_name': 'Hypersensitive response', 'score': 0.7229071}, {'id': 'https://openalex.org/keywords/plant-responses', 'display_name': 'Plant Responses', 'score': 0.493855}], 'concepts': [{'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.8971909}, {'id': 'https://openalex.org/C99971728', 'wikidata': 'https://www.wikidata.org/wiki/Q838181', 'display_name': 'Respiratory burst', 'level': 2, 'score': 0.80107737}, {'id': 'https://openalex.org/C200148052', 'wikidata': 'https://www.wikidata.org/wiki/Q5958568', 'display_name': 'Hypersensitive response', 'level': 4, 'score': 0.7229071}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.6601974}, {'id': 'https://openalex.org/C48349386', 'wikidata': 'https://www.wikidata.org/wiki/Q424361', 'display_name': 'Reactive oxygen species', 'level': 2, 'score': 0.64637494}, {'id': 'https://openalex.org/C57600042', 'wikidata': 'https://www.wikidata.org/wiki/Q227564', 'display_name': 'Oxidative phosphorylation', 'level': 2, 'score': 0.57283294}, {'id': 'https://openalex.org/C2776151105', 'wikidata': 'https://www.wikidata.org/wiki/Q898814', 'display_name': 'Oxidative stress', 'level': 2, 'score': 0.53763455}, {'id': 'https://openalex.org/C2776460866', 'wikidata': 'https://www.wikidata.org/wiki/Q170065', 'display_name': 'Pathogen', 'level': 2, 'score': 0.53195286}, {'id': 'https://openalex.org/C538909803', 'wikidata': 'https://www.wikidata.org/wiki/Q116907', 'display_name': 'Glutathione', 'level': 3, 'score': 0.4779689}, {'id': 'https://openalex.org/C31573885', 'wikidata': 'https://www.wikidata.org/wiki/Q304484', 'display_name': 'Programmed cell death', 'level': 3, 'score': 0.45912468}, {'id': 'https://openalex.org/C93678976', 'wikidata': 'https://www.wikidata.org/wiki/Q4215946', 'display_name': 'Plant disease resistance', 'level': 3, 'score': 0.44534013}, {'id': 'https://openalex.org/C89423630', 'wikidata': 'https://www.wikidata.org/wiki/Q7193', 'display_name': 'Microbiology', 'level': 1, 'score': 0.35316676}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.2933857}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.2696724}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.25994325}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.14543045}, {'id': 'https://openalex.org/C190283241', 'wikidata': 'https://www.wikidata.org/wiki/Q14599311', 'display_name': 'Apoptosis', 'level': 2, 'score': 0.10837218}], 'mesh': [{'descriptor_ui': 'D016923', 'descriptor_name': 'Cell Death', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D017343', 'descriptor_name': 'Genes, Plant', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D013025', 'descriptor_name': 'Glycine max', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D006861', 'descriptor_name': 'Hydrogen Peroxide', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D016897', 'descriptor_name': 'Respiratory Burst', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D015152', 'descriptor_name': 'Blotting, Northern', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002478', 'descriptor_name': 'Cells, Cultured', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015870', 'descriptor_name': 'Gene Expression', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005979', 'descriptor_name': 'Glutathione Peroxidase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005979', 'descriptor_name': 'Glutathione Peroxidase', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D005982', 'descriptor_name': 'Glutathione Transferase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005982', 'descriptor_name': 'Glutathione Transferase', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D013025', 'descriptor_name': 'Glycine max', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013025', 'descriptor_name': 'Glycine max', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D006861', 'descriptor_name': 'Hydrogen Peroxide', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007113', 'descriptor_name': 'Immunity, Innate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007113', 'descriptor_name': 'Immunity, Innate', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D010935', 'descriptor_name': 'Plant Diseases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010957', 'descriptor_name': 'Plasmids', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018749', 'descriptor_name': 'RNA, Plant', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018749', 'descriptor_name': 'RNA, Plant', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': False}, {'descriptor_ui': 'D018749', 'descriptor_name': 'RNA, Plant', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014158', 'descriptor_name': 'Transcription, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/0092-8674(94)90544-4', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S110447773', 'display_name': 'Cell', 'issn_l': '0092-8674', 'issn': ['0092-8674', '1097-4172'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315673', 'host_organization_name': 'Cell Press', 'host_organization_lineage': ['https://openalex.org/P4310320990', 'https://openalex.org/P4310315673'], 'host_organization_lineage_names': ['Elsevier BV', 'Cell Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/7954825', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.62, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 61, 'referenced_works': ['https://openalex.org/W1517192782', 'https://openalex.org/W1533579770', 'https://openalex.org/W1542042217', 'https://openalex.org/W1568529372', 'https://openalex.org/W1817254206', 'https://openalex.org/W1887520422', 'https://openalex.org/W1932728046', 'https://openalex.org/W1968886514', 'https://openalex.org/W1980445064', 'https://openalex.org/W1981883990', 'https://openalex.org/W1982784171', 'https://openalex.org/W1985014052', 'https://openalex.org/W1989046023', 'https://openalex.org/W1989220317', 'https://openalex.org/W1992045438', 'https://openalex.org/W1994434295', 'https://openalex.org/W1996000832', 'https://openalex.org/W1997208169', 'https://openalex.org/W2002054257', 'https://openalex.org/W2007358741', 'https://openalex.org/W2010094123', 'https://openalex.org/W2021070618', 'https://openalex.org/W2021925456', 'https://openalex.org/W2024556021', 'https://openalex.org/W2031129576', 'https://openalex.org/W2039357309', 'https://openalex.org/W2041293207', 'https://openalex.org/W2045778305', 'https://openalex.org/W2046494212', 'https://openalex.org/W2054996495', 'https://openalex.org/W2058127221', 'https://openalex.org/W2061954020', 'https://openalex.org/W2065301787', 'https://openalex.org/W2067363518', 'https://openalex.org/W2070693959', 'https://openalex.org/W2071268213', 'https://openalex.org/W2074509656', 'https://openalex.org/W2074605517', 'https://openalex.org/W2087151511', 'https://openalex.org/W2089813543', 'https://openalex.org/W2095397893', 'https://openalex.org/W2103010812', 'https://openalex.org/W2107140146', 'https://openalex.org/W2111456180', 'https://openalex.org/W2120695363', 'https://openalex.org/W2125000085', 'https://openalex.org/W2132886964', 'https://openalex.org/W2134902158', 'https://openalex.org/W2143772496', 'https://openalex.org/W2149634195', 'https://openalex.org/W2153235080', 'https://openalex.org/W2156371591', 'https://openalex.org/W2157135555', 'https://openalex.org/W2158748165', 'https://openalex.org/W2164907387', 'https://openalex.org/W2168727725', 'https://openalex.org/W2173762551', 'https://openalex.org/W2329241021', 'https://openalex.org/W4237516951', 'https://openalex.org/W4255600560', 'https://openalex.org/W617472555'], 'related_works': ['https://openalex.org/W55754429', 'https://openalex.org/W2741169488', 'https://openalex.org/W2596680468', 'https://openalex.org/W2400244250', 'https://openalex.org/W2170604154', 'https://openalex.org/W2164546956', 'https://openalex.org/W2148967733', 'https://openalex.org/W2081051776', 'https://openalex.org/W1857496160', 'https://openalex.org/W1502036893'], 'abstract_inverted_index': {'Microbial': [0], 'elicitors': [1], 'or': [2], 'attempted': [3], 'infection': [4], 'with': [5], 'an': [6], 'avirulent': [7], 'pathogen': [8], 'strain': [9], 'causes': [10], 'the': [11, 30, 56, 76, 84, 92], 'rapid': [12], 'production': [13], 'of': [14, 32, 44, 61, 86, 94], 'reactive': [15], 'oxygen': [16], 'intermediates.': [17], 'We': [18], 'report': [19], 'here': [20], 'that': [21], 'H2O2': [22, 74], 'from': [23, 75], 'this': [24], 'oxidative': [25, 77], 'burst': [26, 78], 'not': [27], 'only': [28], 'drives': [29], 'cross-linking': [31], 'cell': [33], 'wall': [34], 'structural': [35], 'proteins,': [36], 'but': [37], 'also': [38], 'functions': [39], 'as': [40, 51, 67], 'a': [41, 52, 80, 87], 'local': [42], 'trigger': [43], 'programmed': [45], 'death': [46], 'in': [47, 58, 83], 'challenged': [48], 'cells': [49, 60], 'and': [50, 70], 'diffusible': [53], 'signal': [54], 'for': [55], 'induction': [57], 'adjacent': [59], 'genes': [62], 'encoding': [63], 'cellular': [64], 'protectants': [65], 'such': [66], 'glutathione': [68, 71], 'S-transferase': [69], 'peroxidase.': [72], 'Thus,': [73], 'plays': [79], 'key': [81], 'role': [82], 'orchestration': [85], 'localized': [88], 'hypersensitive': [89], 'response': [90], 'during': [91], 'expression': [93], 'plant': [95], 'disease': [96], 'resistance.': [97]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2059555945', 'counts_by_year': [{'year': 2024, 'cited_by_count': 29}, {'year': 2023, 'cited_by_count': 52}, {'year': 2022, 'cited_by_count': 71}, {'year': 2021, 'cited_by_count': 55}, {'year': 2020, 'cited_by_count': 65}, {'year': 2019, 'cited_by_count': 68}, {'year': 2018, 'cited_by_count': 70}, {'year': 2017, 'cited_by_count': 63}, {'year': 2016, 'cited_by_count': 79}, {'year': 2015, 'cited_by_count': 85}, {'year': 2014, 'cited_by_count': 90}, {'year': 2013, 'cited_by_count': 90}, {'year': 2012, 'cited_by_count': 82}], 'updated_date': '2024-09-10T07:38:41.439520', 'created_date': '2016-06-24'}