Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2052129538', 'doi': 'https://doi.org/10.1073/pnas.0610924104', 'title': 'Clustering of peptidoglycan recognition protein-SA is required for sensing lysine-type peptidoglycan in insects', 'display_name': 'Clustering of peptidoglycan recognition protein-SA is required for sensing lysine-type peptidoglycan in insects', 'publication_year': 2007, 'publication_date': '2007-04-05', 'ids': {'openalex': 'https://openalex.org/W2052129538', 'doi': 'https://doi.org/10.1073/pnas.0610924104', 'mag': '2052129538', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/17409189', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/1871832'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1073/pnas.0610924104', 'pdf_url': 'https://www.pnas.org/doi/pdf/10.1073/pnas.0610924104', 'source': {'id': 'https://openalex.org/S125754415', 'display_name': 'Proceedings of the National Academy of Sciences', 'issn_l': '0027-8424', 'issn': ['0027-8424', '1091-6490'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320052', 'host_organization_name': 'National Academy of Sciences', 'host_organization_lineage': ['https://openalex.org/P4310320052'], 'host_organization_lineage_names': ['National Academy of Sciences'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://www.pnas.org/doi/pdf/10.1073/pnas.0610924104', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5100339669', 'display_name': 'Ji-Won Park', 'orcid': 'https://orcid.org/0000-0001-8580-7847'}, 'institutions': [{'id': 'https://openalex.org/I4921948', 'display_name': 'Pusan National University', 'ror': 'https://ror.org/01an57a31', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I4921948']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Ji-Won Park', 'raw_affiliation_strings': ['*National Research Laboratory of Defense Proteins, College of Pharmacy, Pusan National University, Busan 609-735, Korea;'], 'affiliations': [{'raw_affiliation_string': '*National Research Laboratory of Defense Proteins, College of Pharmacy, Pusan National University, Busan 609-735, Korea;', 'institution_ids': ['https://openalex.org/I4921948']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5027388422', 'display_name': 'Chan‐Hee Kim', 'orcid': 'https://orcid.org/0000-0002-5315-4981'}, 'institutions': [{'id': 'https://openalex.org/I4921948', 'display_name': 'Pusan National University', 'ror': 'https://ror.org/01an57a31', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I4921948']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Chan-Hee Kim', 'raw_affiliation_strings': ['*National Research Laboratory of Defense Proteins, College of Pharmacy, Pusan National University, Busan 609-735, Korea;'], 'affiliations': [{'raw_affiliation_string': '*National Research Laboratory of Defense Proteins, College of Pharmacy, Pusan National University, Busan 609-735, Korea;', 'institution_ids': ['https://openalex.org/I4921948']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100349771', 'display_name': 'Jung‐Hyun Kim', 'orcid': 'https://orcid.org/0000-0002-9496-9474'}, 'institutions': [{'id': 'https://openalex.org/I4921948', 'display_name': 'Pusan National University', 'ror': 'https://ror.org/01an57a31', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I4921948']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Jung-Hyun Kim', 'raw_affiliation_strings': ['*National Research Laboratory of Defense Proteins, College of Pharmacy, Pusan National University, Busan 609-735, Korea;'], 'affiliations': [{'raw_affiliation_string': '*National Research Laboratory of Defense Proteins, College of Pharmacy, Pusan National University, Busan 609-735, Korea;', 'institution_ids': ['https://openalex.org/I4921948']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5030434879', 'display_name': 'Byung-Rok Je', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4921948', 'display_name': 'Pusan National University', 'ror': 'https://ror.org/01an57a31', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I4921948']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Byung-Rok Je', 'raw_affiliation_strings': ['*National Research Laboratory of Defense Proteins, College of Pharmacy, Pusan National University, Busan 609-735, Korea;'], 'affiliations': [{'raw_affiliation_string': '*National Research Laboratory of Defense Proteins, College of Pharmacy, Pusan National University, Busan 609-735, Korea;', 'institution_ids': ['https://openalex.org/I4921948']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5066449089', 'display_name': 'Kyung‐Baeg Roh', 'orcid': 'https://orcid.org/0000-0003-4542-5582'}, 'institutions': [{'id': 'https://openalex.org/I4921948', 'display_name': 'Pusan National University', 'ror': 'https://ror.org/01an57a31', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I4921948']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Kyung-Baeg Roh', 'raw_affiliation_strings': ['*National Research Laboratory of Defense Proteins, College of Pharmacy, Pusan National University, Busan 609-735, Korea;'], 'affiliations': [{'raw_affiliation_string': '*National Research Laboratory of Defense Proteins, College of Pharmacy, Pusan National University, Busan 609-735, Korea;', 'institution_ids': ['https://openalex.org/I4921948']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100426993', 'display_name': 'Su-Jin Kim', 'orcid': 'https://orcid.org/0009-0005-8829-7623'}, 'institutions': [{'id': 'https://openalex.org/I4921948', 'display_name': 'Pusan National University', 'ror': 'https://ror.org/01an57a31', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I4921948']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Su-Jin Kim', 'raw_affiliation_strings': ['*National Research Laboratory of Defense Proteins, College of Pharmacy, Pusan National University, Busan 609-735, Korea;'], 'affiliations': [{'raw_affiliation_string': '*National Research Laboratory of Defense Proteins, College of Pharmacy, Pusan National University, Busan 609-735, Korea;', 'institution_ids': ['https://openalex.org/I4921948']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5000012962', 'display_name': 'Hyeon‐Hwa Lee', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4921948', 'display_name': 'Pusan National University', 'ror': 'https://ror.org/01an57a31', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I4921948']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Hyeon-Hwa Lee', 'raw_affiliation_strings': ['*National Research Laboratory of Defense Proteins, College of Pharmacy, Pusan National University, Busan 609-735, Korea;'], 'affiliations': [{'raw_affiliation_string': '*National Research Laboratory of Defense Proteins, College of Pharmacy, Pusan National University, Busan 609-735, Korea;', 'institution_ids': ['https://openalex.org/I4921948']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5024623181', 'display_name': 'Ji-Hwan Ryu', 'orcid': 'https://orcid.org/0000-0001-6969-7465'}, 'institutions': [{'id': 'https://openalex.org/I138925566', 'display_name': 'Ewha Womans University', 'ror': 'https://ror.org/053fp5c05', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I138925566']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Ji-Hwan Ryu', 'raw_affiliation_strings': ["Division of Molecular Life Science, Ewha Woman's University, Seoul 120-750, Korea; and"], 'affiliations': [{'raw_affiliation_string': "Division of Molecular Life Science, Ewha Woman's University, Seoul 120-750, Korea; and", 'institution_ids': ['https://openalex.org/I138925566']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5077156634', 'display_name': 'Jae-Hong Lim', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I123900574', 'display_name': 'Pohang University of Science and Technology', 'ror': 'https://ror.org/04xysgw12', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I123900574']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Jae-Hong Lim', 'raw_affiliation_strings': ['Division of Molecular and Life Sciences, Department of Life Sciences, Center for Biomolecular Recognition, Pohang University of Science and Technology, Pohang, Gyeongbuk 790-784, Korea'], 'affiliations': [{'raw_affiliation_string': 'Division of Molecular and Life Sciences, Department of Life Sciences, Center for Biomolecular Recognition, Pohang University of Science and Technology, Pohang, Gyeongbuk 790-784, Korea', 'institution_ids': ['https://openalex.org/I123900574']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5014349488', 'display_name': 'Byung‐Ha Oh', 'orcid': 'https://orcid.org/0000-0002-6437-8470'}, 'institutions': [{'id': 'https://openalex.org/I123900574', 'display_name': 'Pohang University of Science and Technology', 'ror': 'https://ror.org/04xysgw12', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I123900574']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Byung-Ha Oh', 'raw_affiliation_strings': ['Division of Molecular and Life Sciences, Department of Life Sciences, Center for Biomolecular Recognition, Pohang University of Science and Technology, Pohang, Gyeongbuk 790-784, Korea'], 'affiliations': [{'raw_affiliation_string': 'Division of Molecular and Life Sciences, Department of Life Sciences, Center for Biomolecular Recognition, Pohang University of Science and Technology, Pohang, Gyeongbuk 790-784, Korea', 'institution_ids': ['https://openalex.org/I123900574']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100638533', 'display_name': 'Won‐Jae Lee', 'orcid': 'https://orcid.org/0000-0002-1438-8005'}, 'institutions': [{'id': 'https://openalex.org/I138925566', 'display_name': 'Ewha Womans University', 'ror': 'https://ror.org/053fp5c05', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I138925566']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Won-Jae Lee', 'raw_affiliation_strings': ["Division of Molecular Life Science, Ewha Woman's University, Seoul 120-750, Korea; and"], 'affiliations': [{'raw_affiliation_string': "Division of Molecular Life Science, Ewha Woman's University, Seoul 120-750, Korea; and", 'institution_ids': ['https://openalex.org/I138925566']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5058577911', 'display_name': 'Nam‐Chul Ha', 'orcid': 'https://orcid.org/0000-0003-4813-748X'}, 'institutions': [{'id': 'https://openalex.org/I4921948', 'display_name': 'Pusan National University', 'ror': 'https://ror.org/01an57a31', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I4921948']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Nam-Chul Ha', 'raw_affiliation_strings': ['*National Research Laboratory of Defense Proteins, College of Pharmacy, Pusan National University, Busan 609-735, Korea;'], 'affiliations': [{'raw_affiliation_string': '*National Research Laboratory of Defense Proteins, College of Pharmacy, Pusan National University, Busan 609-735, Korea;', 'institution_ids': ['https://openalex.org/I4921948']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5035671229', 'display_name': 'Bok‐Luel Lee', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4921948', 'display_name': 'Pusan National University', 'ror': 'https://ror.org/01an57a31', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I4921948']}], 'countries': ['KR'], 'is_corresponding': True, 'raw_author_name': 'Bok-Luel Lee', 'raw_affiliation_strings': ['*National Research Laboratory of Defense Proteins, College of Pharmacy, Pusan National University, Busan 609-735, Korea;'], 'affiliations': [{'raw_affiliation_string': '*National Research Laboratory of Defense Proteins, College of Pharmacy, Pusan National University, Busan 609-735, Korea;', 'institution_ids': ['https://openalex.org/I4921948']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': ['https://openalex.org/A5035671229'], 'corresponding_institution_ids': ['https://openalex.org/I4921948'], 'apc_list': None, 'apc_paid': None, 'fwci': 5.333, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 145, 'citation_normalized_percentile': {'value': 0.999907, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '104', 'issue': '16', 'first_page': '6602', 'last_page': '6607'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11403', 'display_name': 'Invertebrate Immunity and Host Defense Mechanisms', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11403', 'display_name': 'Invertebrate Immunity and Host Defense Mechanisms', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12134', 'display_name': 'Insect Symbiosis and Microbial Interactions', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/1109', 'display_name': 'Insect Science'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10423', 'display_name': 'Neuroscience and Genetics of Drosophila Melanogaster', 'score': 0.9979, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/prophenoloxidase', 'display_name': 'Prophenoloxidase', 'score': 0.97511697}, {'id': 'https://openalex.org/keywords/pathogen-recognition', 'display_name': 'Pathogen Recognition', 'score': 0.48848}], 'concepts': [{'id': 'https://openalex.org/C2776634448', 'wikidata': 'https://www.wikidata.org/wiki/Q206920', 'display_name': 'Peptidoglycan', 'level': 3, 'score': 0.9764428}, {'id': 'https://openalex.org/C2781271842', 'wikidata': 'https://www.wikidata.org/wiki/Q17090067', 'display_name': 'Prophenoloxidase', 'level': 4, 'score': 0.97511697}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.6696824}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.62301874}, {'id': 'https://openalex.org/C2776966407', 'wikidata': 'https://www.wikidata.org/wiki/Q24779410', 'display_name': 'Lysozyme', 'level': 2, 'score': 0.45265502}, {'id': 'https://openalex.org/C89423630', 'wikidata': 'https://www.wikidata.org/wiki/Q7193', 'display_name': 'Microbiology', 'level': 1, 'score': 0.32986403}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.15976766}, {'id': 'https://openalex.org/C136449434', 'wikidata': 'https://www.wikidata.org/wiki/Q428253', 'display_name': 'Innate immune system', 'level': 3, 'score': 0.15244001}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D002352', 'descriptor_name': 'Carrier Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D004331', 'descriptor_name': 'Drosophila melanogaster', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D008239', 'descriptor_name': 'Lysine', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D010457', 'descriptor_name': 'Peptidoglycan', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000595', 'descriptor_name': 'Amino Acid Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002352', 'descriptor_name': 'Carrier Proteins', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D002352', 'descriptor_name': 'Carrier Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004156', 'descriptor_name': 'Catechol Oxidase', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D004156', 'descriptor_name': 'Catechol Oxidase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004331', 'descriptor_name': 'Drosophila melanogaster', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D004331', 'descriptor_name': 'Drosophila melanogaster', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004792', 'descriptor_name': 'Enzyme Precursors', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D004792', 'descriptor_name': 'Enzyme Precursors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008239', 'descriptor_name': 'Lysine', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D008239', 'descriptor_name': 'Lysine', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D008239', 'descriptor_name': 'Lysine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008969', 'descriptor_name': 'Molecular Sequence Data', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010457', 'descriptor_name': 'Peptidoglycan', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D010457', 'descriptor_name': 'Peptidoglycan', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010457', 'descriptor_name': 'Peptidoglycan', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D013211', 'descriptor_name': 'Staphylococcus aureus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013211', 'descriptor_name': 'Staphylococcus aureus', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D013211', 'descriptor_name': 'Staphylococcus aureus', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1073/pnas.0610924104', 'pdf_url': 'https://www.pnas.org/doi/pdf/10.1073/pnas.0610924104', 'source': {'id': 'https://openalex.org/S125754415', 'display_name': 'Proceedings of the National Academy of Sciences', 'issn_l': '0027-8424', 'issn': ['0027-8424', '1091-6490'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320052', 'host_organization_name': 'National Academy of Sciences', 'host_organization_lineage': ['https://openalex.org/P4310320052'], 'host_organization_lineage_names': ['National Academy of Sciences'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc1871832', 'pdf_url': 'https://europepmc.org/articles/pmc1871832?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1871832', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/17409189', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1073/pnas.0610924104', 'pdf_url': 'https://www.pnas.org/doi/pdf/10.1073/pnas.0610924104', 'source': {'id': 'https://openalex.org/S125754415', 'display_name': 'Proceedings of the National Academy of Sciences', 'issn_l': '0027-8424', 'issn': ['0027-8424', '1091-6490'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320052', 'host_organization_name': 'National Academy of Sciences', 'host_organization_lineage': ['https://openalex.org/P4310320052'], 'host_organization_lineage_names': ['National Academy of Sciences'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 33, 'referenced_works': ['https://openalex.org/W1978065201', 'https://openalex.org/W1982666820', 'https://openalex.org/W1991807082', 'https://openalex.org/W1994599007', 'https://openalex.org/W1997888230', 'https://openalex.org/W1997961062', 'https://openalex.org/W1999257669', 'https://openalex.org/W2000530029', 'https://openalex.org/W2016143376', 'https://openalex.org/W2017482741', 'https://openalex.org/W2018658170', 'https://openalex.org/W2027854362', 'https://openalex.org/W2028754942', 'https://openalex.org/W2034589857', 'https://openalex.org/W2035241610', 'https://openalex.org/W2046656994', 'https://openalex.org/W2047549277', 'https://openalex.org/W2048657805', 'https://openalex.org/W2058681699', 'https://openalex.org/W2063599549', 'https://openalex.org/W2069499520', 'https://openalex.org/W2079825884', 'https://openalex.org/W2081613273', 'https://openalex.org/W2092259900', 'https://openalex.org/W2097042447', 'https://openalex.org/W2100241857', 'https://openalex.org/W2102517829', 'https://openalex.org/W2124786856', 'https://openalex.org/W2128584517', 'https://openalex.org/W2133031337', 'https://openalex.org/W2134741924', 'https://openalex.org/W2136986799', 'https://openalex.org/W2145309398'], 'related_works': ['https://openalex.org/W4241520150', 'https://openalex.org/W4240306090', 'https://openalex.org/W3087470651', 'https://openalex.org/W2152457344', 'https://openalex.org/W2118058022', 'https://openalex.org/W2083371863', 'https://openalex.org/W2052129538', 'https://openalex.org/W2037134815', 'https://openalex.org/W1985241441', 'https://openalex.org/W1974791086'], 'abstract_inverted_index': {'Recognition': [0], 'of': [1, 12, 25, 40, 66, 77, 89, 98, 104, 131, 160, 165, 183], 'lysine-type': [2, 26, 92, 161], 'peptidoglycan': [3, 5, 58, 71, 93, 162], 'by': [4, 101, 143], 'recognition': [6], 'protein': [7, 112, 126, 171], '(PGRP)-SA': [8], 'provokes': [9], 'the': [10, 13, 41, 46, 51, 70, 75, 78, 85, 96, 109, 134, 174, 181, 185], 'activation': [11, 48, 76, 136, 182], 'Toll': [14, 43, 186], 'and': [15, 45, 115, 123, 173, 187], 'prophenoloxidase': [16, 47, 79, 135, 188], 'pathways.': [17, 189], 'Here': [18], 'we': [19, 60, 150], 'reveal': [20], 'that': [21, 64, 84, 167], 'a': [22, 28, 37, 116, 145, 152, 157], 'soluble': [23], 'fragment': [24], 'peptidoglycan,': [27], 'long': [29], 'glycan': [30], 'chain': [31], 'with': [32], 'short': [33], 'stem': [34], 'peptides,': [35], 'is': [36, 72, 138], 'potent': [38], 'activator': [39], 'Drosophila': [42], 'pathway': [44], 'cascade': [49, 137], 'in': [50, 133, 141], 'beetle': [52], 'Tenebrio': [53], 'molitor': [54], '.': [55], 'Using': [56], 'this': [57], 'fragment,': [59], 'present': [61], 'biochemical': [62], 'evidence': [63], 'clustering': [65, 103, 164], 'PGRP-SA': [67, 166], 'molecules': [68], 'on': [69], 'required': [73], 'for': [74, 163], 'cascade.': [80], 'We': [81], 'subsequently': [82], 'highlight': [83], 'lysozyme-mediated': [86], 'partial': [87], 'digestion': [88], 'highly': [90], 'cross-linked': [91], 'dramatically': [94], 'increases': [95], 'binding': [97], 'PGRP-SA,': [99, 105], 'presumably': [100], 'inducing': [102], 'which': [106, 178], 'then': [107], 'recruits': [108, 168], 'Gram-negative': [110, 169], 'bacteria-binding': [111, 170], '1': [113, 172], 'homologue': [114], 'modular': [117, 175], 'serine': [118, 176], 'protease': [119], 'containing': [120], 'low-density': [121], 'lipoprotein': [122], 'complement': [124], 'control': [125], 'domains.': [127], 'The': [128], 'crucial': [129], 'role': [130], 'lysozyme': [132, 146, 155], 'further': [139], 'confirmed': [140], 'vivo': [142], 'using': [144], 'inhibitor.': [147], 'Taken': [148], 'together,': [149], 'propose': [151], 'model': [153], 'whereby': [154], 'presents': [156], 'processed': [158], 'form': [159], 'protease,': [177], 'leads': [179], 'to': [180], 'both': [184]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2052129538', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 4}, {'year': 2022, 'cited_by_count': 9}, {'year': 2021, 'cited_by_count': 5}, {'year': 2020, 'cited_by_count': 8}, {'year': 2019, 'cited_by_count': 8}, {'year': 2018, 'cited_by_count': 5}, {'year': 2017, 'cited_by_count': 6}, {'year': 2016, 'cited_by_count': 6}, {'year': 2015, 'cited_by_count': 7}, {'year': 2014, 'cited_by_count': 10}, {'year': 2013, 'cited_by_count': 13}, {'year': 2012, 'cited_by_count': 11}], 'updated_date': '2024-09-17T15:45:09.642264', 'created_date': '2016-06-24'}