Kidney Injury Molecule-1 (KIM-1), a Putative Epithelial Cell Adhesion Molecule Containing a Novel Immunoglobulin Domain, Is Up-regulated in Renal Cells after Injury

Name: Work Video:
Duration: 3 min 30 s
Takaharu Ichimura; Joseph V. Bonventre; Véronique Bailly; Henry Wei; Catherine Hession; Richard L. Cate; Michele Sanicola
{'id': 'https://openalex.org/W2045421375', 'doi': 'https://doi.org/10.1074/jbc.273.7.4135', 'title': 'Kidney Injury Molecule-1 (KIM-1), a Putative Epithelial Cell Adhesion Molecule Containing a Novel Immunoglobulin Domain, Is Up-regulated in Renal Cells after Injury', 'display_name': 'Kidney Injury Molecule-1 (KIM-1), a Putative Epithelial Cell Adhesion Molecule Containing a Novel Immunoglobulin Domain, Is Up-regulated in Renal Cells after Injury', 'publication_year': 1998, 'publication_date': '1998-02-01', 'ids': {'openalex': 'https://openalex.org/W2045421375', 'doi': 'https://doi.org/10.1074/jbc.273.7.4135', 'mag': '2045421375', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/9461608'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1074/jbc.273.7.4135', 'pdf_url': 'http://www.jbc.org/article/S0021925817471821/pdf', 'source': {'id': 'https://openalex.org/S140251998', 'display_name': 'Journal of Biological Chemistry', 'issn_l': '0021-9258', 'issn': ['0021-9258', '1067-8816', '1083-351X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'hybrid', 'oa_url': 'http://www.jbc.org/article/S0021925817471821/pdf', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5080273574', 'display_name': 'Takaharu Ichimura', 'orcid': 'https://orcid.org/0000-0002-3106-5224'}, 'institutions': [{'id': 'https://openalex.org/I136199984', 'display_name': 'Harvard University', 'ror': 'https://ror.org/03vek6s52', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I136199984']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Takaharu Ichimura', 'raw_affiliation_strings': ['Renal Unit, Medical Services, Massachusetts General Hospital East and the Department of Medicine, Harvard Medical School, Boston, Massachusetts 02129'], 'affiliations': [{'raw_affiliation_string': 'Renal Unit, Medical Services, Massachusetts General Hospital East and the Department of Medicine, Harvard Medical School, Boston, Massachusetts 02129', 'institution_ids': ['https://openalex.org/I136199984']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5089781525', 'display_name': 'Joseph V. Bonventre', 'orcid': 'https://orcid.org/0000-0001-7144-386X'}, 'institutions': [{'id': 'https://openalex.org/I136199984', 'display_name': 'Harvard University', 'ror': 'https://ror.org/03vek6s52', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I136199984']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Joseph V. Bonventre', 'raw_affiliation_strings': ['Renal Unit, Medical Services, Massachusetts General Hospital East and the Department of Medicine, Harvard Medical School, Boston, Massachusetts 02129'], 'affiliations': [{'raw_affiliation_string': 'Renal Unit, Medical Services, Massachusetts General Hospital East and the Department of Medicine, Harvard Medical School, Boston, Massachusetts 02129', 'institution_ids': ['https://openalex.org/I136199984']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5111779736', 'display_name': 'Véronique Bailly', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1297540436', 'display_name': 'Biogen (United States)', 'ror': 'https://ror.org/02jqkb192', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I1297540436']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Véronique Bailly', 'raw_affiliation_strings': ['Biogen Inc., Cambridge Massachusetts 02142'], 'affiliations': [{'raw_affiliation_string': 'Biogen Inc., Cambridge Massachusetts 02142', 'institution_ids': ['https://openalex.org/I1297540436']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5061399829', 'display_name': 'Henry Wei', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1297540436', 'display_name': 'Biogen (United States)', 'ror': 'https://ror.org/02jqkb192', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I1297540436']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Henry Wei', 'raw_affiliation_strings': ['Biogen Inc., Cambridge Massachusetts 02142'], 'affiliations': [{'raw_affiliation_string': 'Biogen Inc., Cambridge Massachusetts 02142', 'institution_ids': ['https://openalex.org/I1297540436']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5110243681', 'display_name': 'Catherine Hession', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1297540436', 'display_name': 'Biogen (United States)', 'ror': 'https://ror.org/02jqkb192', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I1297540436']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Catherine A. Hession', 'raw_affiliation_strings': ['Biogen Inc., Cambridge Massachusetts 02142'], 'affiliations': [{'raw_affiliation_string': 'Biogen Inc., Cambridge Massachusetts 02142', 'institution_ids': ['https://openalex.org/I1297540436']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5044747824', 'display_name': 'Richard L. Cate', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1297540436', 'display_name': 'Biogen (United States)', 'ror': 'https://ror.org/02jqkb192', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I1297540436']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Richard L. Cate', 'raw_affiliation_strings': ['Biogen Inc., Cambridge Massachusetts 02142'], 'affiliations': [{'raw_affiliation_string': 'Biogen Inc., Cambridge Massachusetts 02142', 'institution_ids': ['https://openalex.org/I1297540436']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5077443874', 'display_name': 'Michele Sanicola', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1297540436', 'display_name': 'Biogen (United States)', 'ror': 'https://ror.org/02jqkb192', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I1297540436']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Michele Sanicola', 'raw_affiliation_strings': ['Biogen Inc., Cambridge Massachusetts 02142'], 'affiliations': [{'raw_affiliation_string': 'Biogen Inc., Cambridge Massachusetts 02142', 'institution_ids': ['https://openalex.org/I1297540436']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 2500, 'currency': 'USD', 'value_usd': 2500, 'provenance': 'doaj'}, 'apc_paid': {'value': 2500, 'currency': 'USD', 'value_usd': 2500, 'provenance': 'doaj'}, 'fwci': 1.841, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 1189, 'citation_normalized_percentile': {'value': 0.99997, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '273', 'issue': '7', 'first_page': '4135', 'last_page': '4142'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12140', 'display_name': 'Renal and related cancers', 'score': 0.983, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12140', 'display_name': 'Renal and related cancers', 'score': 0.983, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12672', 'display_name': 'Phagocytosis and Immune Regulation', 'score': 0.9607, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/renal-injury', 'display_name': 'Renal Injury', 'score': 0.49162465}, {'id': 'https://openalex.org/keywords/immunoglobulin-domain', 'display_name': 'Immunoglobulin domain', 'score': 0.48085076}, {'id': 'https://openalex.org/keywords/cell-injury', 'display_name': 'Cell injury', 'score': 0.44930014}, {'id': 'https://openalex.org/keywords/immunoglobulin-superfamily', 'display_name': 'Immunoglobulin superfamily', 'score': 0.4422561}], 'concepts': [{'id': 'https://openalex.org/C16224149', 'wikidata': 'https://www.wikidata.org/wiki/Q187637', 'display_name': 'Cell adhesion molecule', 'level': 2, 'score': 0.68374}, {'id': 'https://openalex.org/C159654299', 'wikidata': 'https://www.wikidata.org/wiki/Q79460', 'display_name': 'Antibody', 'level': 2, 'score': 0.5717675}, {'id': 'https://openalex.org/C2780091579', 'wikidata': 'https://www.wikidata.org/wiki/Q9377', 'display_name': 'Kidney', 'level': 2, 'score': 0.5215292}, {'id': 'https://openalex.org/C2991844318', 'wikidata': 'https://www.wikidata.org/wiki/Q476921', 'display_name': 'Renal injury', 'level': 3, 'score': 0.49162465}, {'id': 'https://openalex.org/C149774189', 'wikidata': 'https://www.wikidata.org/wiki/Q24770541', 'display_name': 'Immunoglobulin domain', 'level': 3, 'score': 0.48085076}, {'id': 'https://openalex.org/C32909587', 'wikidata': 'https://www.wikidata.org/wiki/Q11369', 'display_name': 'Molecule', 'level': 2, 'score': 0.47285986}, {'id': 'https://openalex.org/C85789140', 'wikidata': 'https://www.wikidata.org/wiki/Q187640', 'display_name': 'Cell adhesion', 'level': 3, 'score': 0.46809176}, {'id': 'https://openalex.org/C2993711000', 'wikidata': 'https://www.wikidata.org/wiki/Q5058184', 'display_name': 'Cell injury', 'level': 3, 'score': 0.44930014}, {'id': 'https://openalex.org/C91682701', 'wikidata': 'https://www.wikidata.org/wiki/Q41797304', 'display_name': 'Immunoglobulin superfamily', 'level': 3, 'score': 0.4422561}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.43836066}, {'id': 'https://openalex.org/C84416704', 'wikidata': 'https://www.wikidata.org/wiki/Q188666', 'display_name': 'Adhesion', 'level': 2, 'score': 0.4113471}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.4041604}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.33976793}, {'id': 'https://openalex.org/C1491633281', 'wikidata': 'https://www.wikidata.org/wiki/Q7868', 'display_name': 'Cell', 'level': 2, 'score': 0.3287626}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.24175292}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.20126137}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.12139839}, {'id': 'https://openalex.org/C190283241', 'wikidata': 'https://www.wikidata.org/wiki/Q14599311', 'display_name': 'Apoptosis', 'level': 2, 'score': 0.10063049}, {'id': 'https://openalex.org/C178790620', 'wikidata': 'https://www.wikidata.org/wiki/Q11351', 'display_name': 'Organic chemistry', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D015815', 'descriptor_name': 'Cell Adhesion Molecules', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D007136', 'descriptor_name': 'Immunoglobulins', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D007668', 'descriptor_name': 'Kidney', 'qualifier_ui': 'Q000293', 'qualifier_name': 'injuries', 'is_major_topic': True}, {'descriptor_ui': 'D008565', 'descriptor_name': 'Membrane Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000595', 'descriptor_name': 'Amino Acid Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001483', 'descriptor_name': 'Base Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015815', 'descriptor_name': 'Cell Adhesion Molecules', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003001', 'descriptor_name': 'Cloning, Molecular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005786', 'descriptor_name': 'Gene Expression Regulation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005786', 'descriptor_name': 'Gene Expression Regulation', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D007136', 'descriptor_name': 'Immunoglobulins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007150', 'descriptor_name': 'Immunohistochemistry', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017403', 'descriptor_name': 'In Situ Hybridization', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007511', 'descriptor_name': 'Ischemia', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007511', 'descriptor_name': 'Ischemia', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D007668', 'descriptor_name': 'Kidney', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007668', 'descriptor_name': 'Kidney', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008969', 'descriptor_name': 'Molecular Sequence Data', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012333', 'descriptor_name': 'RNA, Messenger', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012333', 'descriptor_name': 'RNA, Messenger', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017207', 'descriptor_name': 'Rats, Sprague-Dawley', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011994', 'descriptor_name': 'Recombinant Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011994', 'descriptor_name': 'Recombinant Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D017422', 'descriptor_name': 'Sequence Analysis, DNA', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017386', 'descriptor_name': 'Sequence Homology, Amino Acid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015854', 'descriptor_name': 'Up-Regulation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015854', 'descriptor_name': 'Up-Regulation', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1074/jbc.273.7.4135', 'pdf_url': 'http://www.jbc.org/article/S0021925817471821/pdf', 'source': {'id': 'https://openalex.org/S140251998', 'display_name': 'Journal of Biological Chemistry', 'issn_l': '0021-9258', 'issn': ['0021-9258', '1067-8816', '1083-351X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/9461608', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1074/jbc.273.7.4135', 'pdf_url': 'http://www.jbc.org/article/S0021925817471821/pdf', 'source': {'id': 'https://openalex.org/S140251998', 'display_name': 'Journal of Biological Chemistry', 'issn_l': '0021-9258', 'issn': ['0021-9258', '1067-8816', '1083-351X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 39, 'referenced_works': ['https://openalex.org/W1503291606', 'https://openalex.org/W1545659486', 'https://openalex.org/W1922925354', 'https://openalex.org/W1966528142', 'https://openalex.org/W1966899328', 'https://openalex.org/W1969422658', 'https://openalex.org/W1969761237', 'https://openalex.org/W1975304761', 'https://openalex.org/W1980726194', 'https://openalex.org/W1983562800', 'https://openalex.org/W1992815918', 'https://openalex.org/W2005453259', 'https://openalex.org/W2027322371', 'https://openalex.org/W2027590165', 'https://openalex.org/W2038019625', 'https://openalex.org/W2050918242', 'https://openalex.org/W2051354793', 'https://openalex.org/W2051998916', 'https://openalex.org/W2055043387', 'https://openalex.org/W2063613980', 'https://openalex.org/W2065692062', 'https://openalex.org/W2067709564', 'https://openalex.org/W2070863782', 'https://openalex.org/W2076892293', 'https://openalex.org/W2082584428', 'https://openalex.org/W2085233986', 'https://openalex.org/W2085875957', 'https://openalex.org/W2086417798', 'https://openalex.org/W2103488145', 'https://openalex.org/W2114245705', 'https://openalex.org/W2124415162', 'https://openalex.org/W2128847715', 'https://openalex.org/W2138879032', 'https://openalex.org/W2146989892', 'https://openalex.org/W2165830726', 'https://openalex.org/W2170395027', 'https://openalex.org/W2251380018', 'https://openalex.org/W2408913569', 'https://openalex.org/W4236514815'], 'related_works': ['https://openalex.org/W4211220725', 'https://openalex.org/W3145490520', 'https://openalex.org/W2587274911', 'https://openalex.org/W2152532559', 'https://openalex.org/W2109064194', 'https://openalex.org/W2086212802', 'https://openalex.org/W2086151489', 'https://openalex.org/W2037150903', 'https://openalex.org/W1991111651', 'https://openalex.org/W1985384093'], 'abstract_inverted_index': {'We': [0], 'report': [1], 'the': [2, 39, 76, 136, 151, 154], 'identification': [3], 'of': [4, 38, 45, 153], 'rat': [5], 'and': [6, 22, 82, 102, 112, 122, 141, 157], 'human': [7], 'cDNAs': [8], 'for': [9, 75], 'a': [10, 17, 23, 36, 58, 73, 87], 'type': [11], '1': [12, 51, 66], 'membrane': [13], 'protein': [14, 83], 'that': [15, 105, 126], 'contains': [16], 'novel': [18], 'six-cysteine': [19], 'immunoglobulin-like': [20], 'domain': [21], 'mucin': [24], 'domain;': [25], 'it': [26], 'is': [27, 35, 107, 128], 'named': [28], 'kidney': [29, 92], 'injury': [30], 'molecule-1': [31], '(KIM-1).': [32], 'Structurally,': [33], 'KIM-1': [34, 54, 80, 106, 127, 144], 'member': [37], 'immunoglobulin': [40], 'gene': [41], 'superfamily': [42], 'most': [43], 'reminiscent': [44], 'mucosal': [46], 'addressin': [47], 'cell': [48, 64, 131], 'adhesion': [49, 132], 'molecule': [50, 133], '(MAdCAM-1).': [52], 'Human': [53], 'exhibits': [55], 'homology': [56], 'to': [57, 159], 'monkey': [59], 'gene,': [60], 'hepatitis': [61, 77], 'A': [62, 78], 'virus': [63], 'receptor': [65, 74], '(HAVcr-1),': [67], 'which': [68, 138], 'was': [69], 'identified': [70], 'recently': [71], 'as': [72], 'virus.': [79], 'mRNA': [81], 'are': [84, 94, 139], 'expressed': [85, 108], 'at': [86], 'low': [88], 'level': [89], 'in': [90, 97, 109, 117, 135, 150], 'normal': [91], 'but': [93], 'increased': [95], 'dramatically': [96], 'postischemic': [98, 160], 'kidney.<i>In': [99], 'situ</i>': [100], 'hybridization': [101], 'immunohistochemistry': [103], 'revealed': [104], 'proliferating': [110], 'bromodeoxyuridine-positive': [111], 'dedifferentiated': [113, 140], 'vimentin-positive': [114], 'epithelial': [115, 130], 'cells': [116], 'regenerating': [118], 'proximal': [119], 'tubules.': [120], 'Structure': [121], 'expression': [123], 'data': [124], 'suggest': [125], 'an': [129, 147], 'up-regulated': [134], 'cells,': [137], 'undergoing': [142], 'replication.': [143], 'may': [145], 'play': [146], 'important': [148], 'role': [149], 'restoration': [152], 'morphological': [155], 'integrity': [156], 'function': [158], 'kidney.': [161]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2045421375', 'counts_by_year': [{'year': 2024, 'cited_by_count': 56}, {'year': 2023, 'cited_by_count': 53}, {'year': 2022, 'cited_by_count': 57}, {'year': 2021, 'cited_by_count': 85}, {'year': 2020, 'cited_by_count': 59}, {'year': 2019, 'cited_by_count': 73}, {'year': 2018, 'cited_by_count': 56}, {'year': 2017, 'cited_by_count': 42}, {'year': 2016, 'cited_by_count': 71}, {'year': 2015, 'cited_by_count': 74}, {'year': 2014, 'cited_by_count': 66}, {'year': 2013, 'cited_by_count': 71}, {'year': 2012, 'cited_by_count': 79}], 'updated_date': '2024-12-18T12:12:29.937168', 'created_date': '2016-06-24'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
