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334], 'little': [33, 265], 'known': [35, 46, 267, 278], 'about': [36, 47, 268, 279], 'transporter': [37, 168, 269, 400], 'identity': [38, 270], 'and': [39, 55, 90, 104, 130, 144, 159, 163, 179, 181, 226, 271, 287, 322, 336, 362, 376, 391, 395, 411, 413, 458, 494, 574, 582, 619, 798, 849, 860, 876, 1085, 1088, 1138, 1171, 1201, 1318, 1463, 1506, 1521, 1532, 1542, 1549, 1622, 1642, 1665, 1679, 1697, 1723, 1744, 1824, 1832, 1869, 2048, 2100, 2111, 2127, 2336, 2339, 2389, 2422, 2453, 2570, 2716, 2759, 2774, 2786, 2796, 2803, 2877, 2897, 2921, 2935, 2953, 2979, 2989], 'the': [40, 48, 64, 87, 121, 138, 166, 173, 192, 200, 212, 272, 280, 296, 319, 353, 370, 398, 405, 424, 432, 444, 479, 825, 835, 842, 851, 864, 1048, 1080, 1086, 1158, 1191, 1204, 1217, 1221, 1294, 1331, 1387, 1396, 1467, 1477, 1493, 1544, 1575, 1584, 1591, 1615, 1620, 1634, 1662, 1675, 1695, 1707, 1729, 2076, 2086, 2093, 2102, 2115, 2299, 2331, 2337, 2409, 2442, 2456, 2469, 2473, 2546, 2583, 2640, 2649, 2720, 2730, 2746, 2798, 2829, 2838, 2845, 2870, 2875, 2889, 2918, 2931, 2951, 2963], 'overall': [41, 273, 1680, 2936], 'regulation.': [42, 274], 'Even': [43, 275], 'less': [44, 276], 'mechanism': [49, 281], 'cellular': [51, 283, 495, 635, 721, 804, 1189, 1458, 1471, 1498, 1745, 1885, 1971, 2054, 2440, 2711, 2724, 2751], 'Mg2+uptake.': [52, 284], 'Using': [53, 285, 1342, 2594], 'sealed': [54, 286, 1284, 1343, 1641, 2536, 2595, 2896], 'right-sided': [56, 288], 'rat': [57, 289, 1195, 2446], 'liver': [58, 290, 464, 468, 472, 1205, 1223, 1285, 1376, 2457, 2475, 2537, 2629], 'plasma': [59, 88, 291, 320, 465, 469, 473, 836, 1162, 1192, 1286, 1344, 1377, 1624, 1645, 1676, 2087, 2413, 2443, 2538, 2596, 2630, 2879, 2900, 2932], 'membrane': [60, 292, 1163, 1193, 1297, 1324, 1378, 1618, 2414, 2444, 2549, 2576, 2631, 2873], 'vesicles': [61, 293, 1379, 2632], 'representing': [62, 294], 'either': [63, 295, 1350, 1539, 1650, 2602, 2793, 2905], 'basolateral': [65, 297, 467, 1621, 1654, 1696, 2876, 2909, 2952], '(bLPM)': [66, 298, 1655, 2910], 'apical': [68, 300, 471, 1623, 1651, 1698, 1708, 2878, 2906, 2954, 2964], '(aLPM)': [69, 301, 1652, 2907], 'domain,': [70, 302, 1699, 2955], 'was': [72, 304, 1178, 1279, 1580, 2429, 2531, 2834], 'possible': [73, 305], 'dissect': [75, 307, 1181, 2432], 'three': [76, 207, 308, 439], 'different': [77, 309, 1169, 1183, 2420, 2434], 'transport': [79, 311, 832, 857, 1292, 1325, 1339, 1460, 1586, 2083, 2108, 2544, 2577, 2591, 2713, 2840], 'mechanisms': [80, 312, 1170, 1587, 1690, 2421, 2841, 2946], 'based': [81, 313], 'upon': [82, 187, 314, 419, 1236, 2488], 'inhibition,': [84, 316, 1678, 2934], 'localization': [85, 317, 1609, 1673, 2864, 2929], 'within': [86, 318, 484, 627, 834, 1590, 1674, 1734, 1877, 2085, 2844, 2930], 'membrane,': [89, 321, 1677, 2933], 'directionality.': [91, 323], 'The': [92, 109, 149, 203, 324, 341, 381, 435, 1626, 1682, 2855, 2881, 2912, 2938], 'bLPM': [93, 122, 139, 167, 325, 354, 371, 399], 'possesses': [94, 111, 326, 343], 'only': [95, 196, 327, 428, 1705, 2961], 'one': [96, 328], 'transporter,': [98, 330], 'which': [99, 331, 1323, 1487, 2575, 2740], 'strictly': [101, 125, 333, 357], 'bi-directional,': [103, 335], 'not': [105, 337, 846, 1581, 2097, 2835], 'inhibited': [106, 146, 160, 338, 378, 392, 1573, 2827], 'by': [107, 147, 161, 339, 379, 393, 806, 1157, 1340, 1574, 2056, 2408, 2592, 2828], 'amiloride.': [108, 148, 340, 380], 'aLPM': [110, 193, 342, 425], 'two': [112, 344, 1585, 1596, 1616, 1686, 2839, 2850, 2871, 2942], 'separate': [113, 345, 1161, 1638, 2412, 2893], 'transporters.': [115, 347], 'One,': [116, 348], 'similar': [117, 349], 'in': [120, 185, 352, 417, 793, 874, 1211, 1216, 1322, 1330, 1375, 1386, 1417, 1466, 1479, 1512, 1595, 1614, 1670, 1706, 2043, 2125, 2463, 2468, 2574, 2582, 2628, 2639, 2670, 2719, 2732, 2765, 2849, 2869, 2926, 2962, 2992], 'because': [123, 140, 355, 372, 1515, 2768], 'depends': [126, 358], 'on': [127, 359, 869, 1485, 2120, 2738], 'Na+': [128, 360, 1352, 1391, 1531, 2604, 2644, 2785], 'transport,': [129, 361], 'can': [132, 195, 364, 427, 1227, 1326, 2479, 2578], 'be': [133, 170, 365, 402, 1154, 1327, 1489, 1510, 1572, 1714, 2405, 2579, 2742, 2763, 2826, 2970], 'differentiated': [134, 366], 'from': [135, 367], 'unidirectional': [143, 158, 375, 390], 'fully': [145, 377], 'second': [150, 382, 480, 1730], 'a': [152, 227, 384, 459, 490, 628, 631, 711, 715, 799, 828, 1208, 1482, 1501, 1535, 1603, 1701, 1711, 1740, 1878, 1881, 1961, 1965, 2049, 2079, 2460, 2735, 2754, 2789, 2858, 2957, 2967], 'novel': [153, 385], 'Ca2+/Mg2+': [154, 386, 1702, 2958], 'exchanger': [155, 387, 1703, 2959], 'amiloride': [162, 394, 1095, 2346], 'imipramine.': [164, 396], 'Hence,': [165, 397, 1175, 2426], 'may': [169, 401], 'responsible': [171, 403], 'for': [172, 404, 489, 1156, 1739, 2407, 2995], 'exchange': [174, 406], 'between': [177, 409], 'plasma,': [180, 412], 'vice': [182, 414], 'versa,': [183, 415], 'shown': [184, 416], 'livers': [186, 418], 'metabolic': [189, 421, 493, 624, 1238, 1399, 1743, 1874, 2490, 2652], 'stimulation,': [190, 422], 'whereas': [191, 423, 1700, 2956], 'transporters': [194, 225, 426, 457, 1165, 1185, 1569, 1613, 2416, 2436, 2823, 2868], 'extrude': [197, 429], 'into': [199, 431], 'biliary': [201, 433], 'tract.': [202, 434], 'dissection': [204, 436], 'these': [206, 224, 438, 456, 1151, 1456, 2402, 2709], 'distinct': [208, 440, 1547, 1597, 1669, 2801, 2851, 2925], 'pathways': [209, 441, 970, 1337, 2221, 2589], 'and,': [210, 442], 'therefore,': [211, 443], 'opportunity': [213, 445], 'study': [215, 447, 1290, 1628, 2542, 2883], 'each': [216, 448, 1166, 2417], 'individually': [217, 449], 'will': [218, 450], 'greatly': [219, 451], 'facilitate': [220, 452], 'further': [221, 453], 'characterization': [222, 454], 'better': [228, 460, 1725, 2981], 'understanding': [229, 461], 'Mg2+homeostasis.': [231, 463], 'membranes': [466, 470, 474, 837, 1287, 1646, 2088, 2539, 2901], 'atomic': [475], 'absorption': [476], 'spectophotometry': [477], 'Magnesium,': [478, 1728], 'most': [481, 1731], 'abundant': [482, 1732], 'cation': [483, 1540, 1733, 2794], 'mammalian': [485, 839, 877, 1735, 2090, 2128], 'cells,': [486, 1736], 'necessary': [488, 1416, 1738, 2669], 'variety': [491, 1741], 'functions': [496, 1746], '(1.Flatman': [497, 585, 975, 1054, 1747, 1835, 2226, 2305], 'P.W.': [498, 586, 976, 1055, 1101, 1748, 1836, 2227, 2306, 2352], 'J.': [499, 587, 656, 674, 742, 760, 885, 899, 927, 944, 957, 977, 994, 1023, 1056, 1102, 1246, 1264, 1305, 1365, 1408, 1426, 1443, 1558, 1749, 1837, 1906, 1924, 1992, 2010, 2136, 2150, 2178, 2195, 2208, 2228, 2245, 2274, 2307, 2353, 2498, 2516, 2557, 2617, 2661, 2679, 2696, 2812], 'Membr.': [500, 588, 978, 1057, 1103, 1750, 1838, 2229, 2308, 2354], 'Biol.': [501, 589, 657, 675, 743, 761, 979, 995, 1024, 1058, 1104, 1247, 1265, 1427, 1444, 1751, 1839, 1907, 1925, 1993, 2011, 2230, 2246, 2275, 2309, 2355, 2499, 2517, 2680, 2697], '1984;': [502, 590, 980, 1059, 1105, 1752, 1840, 2231, 2310, 2356], '80:': [503, 591, 981, 1060, 1106, 1753, 1841, 2232, 2311, 2357], '1-14Crossref': [504, 592, 982, 1061, 1107, 1754, 1842, 2233, 2312, 2358], 'PubMed': [505, 552, 593, 608, 645, 665, 683, 697, 731, 751, 769, 783, 919, 935, 963, 983, 1003, 1017, 1032, 1062, 1075, 1108, 1123, 1255, 1273, 1310, 1370, 1413, 1435, 1452, 1563, 1755, 1802, 1843, 1858, 1895, 1915, 1933, 1947, 1981, 2001, 2019, 2033, 2170, 2186, 2214, 2234, 2254, 2268, 2283, 2313, 2326, 2359, 2374, 2507, 2525, 2562, 2622, 2666, 2688, 2705, 2817], 'Scopus': [506, 520, 553, 594, 609, 646, 732, 819, 891, 905, 920, 936, 950, 964, 984, 1063, 1076, 1109, 1124, 1756, 1770, 1803, 1844, 1859, 1896, 1982, 2069, 2142, 2156, 2171, 2187, 2201, 2215, 2235, 2314, 2327, 2360, 2375], '(165)': [507, 595, 985, 1064, 1110, 1757, 1845, 2236, 2315, 2361], 'Google': [508, 522, 532, 540, 555, 596, 611, 648, 666, 684, 698, 734, 752, 770, 784, 821, 893, 907, 922, 938, 952, 966, 986, 1004, 1018, 1033, 1043, 1065, 1078, 1111, 1126, 1136, 1147, 1256, 1274, 1311, 1371, 1414, 1436, 1453, 1564, 1758, 1772, 1782, 1790, 1805, 1846, 1861, 1898, 1916, 1934, 1948, 1984, 2002, 2020, 2034, 2071, 2144, 2158, 2173, 2189, 2203, 2217, 2237, 2255, 2269, 2284, 2294, 2316, 2329, 2362, 2377, 2387, 2398, 2508, 2526, 2563, 2623, 2667, 2689, 2706, 2818], 'Scholar,': [509, 523, 533, 541, 597, 649, 667, 685, 735, 753, 771, 894, 908, 923, 939, 953, 987, 1005, 1034, 1066, 1112, 1127, 1137, 1257, 1759, 1773, 1783, 1791, 1847, 1899, 1917, 1935, 1985, 2003, 2021, 2145, 2159, 2174, 2190, 2204, 2238, 2256, 2285, 2317, 2363, 2378, 2388, 2509], '2.Maguire': [510, 1760], 'M.E.': [511, 527, 1761, 1777], 'Ann.': [512, 1762], 'N.': [513, 1763], 'Y.': [514, 1764], 'Acad.': [515, 1765], 'Sci.': [516, 1766], '1988;': [517, 916, 1767, 2167], '531:': [518, 1768], '201-217Crossref': [519, 1769], '(28)': [521, 1771], '3.Grubbs': [524, 1774], 'R.D.': [525, 1775], 'Maguire': [526, 1776], 'Magnesium.': [528, 536, 1778, 1786], '1987;': [529, 947, 1026, 1779, 2198, 2277], '6:': [530, 1780], '113-124PubMed': [531, 1781], '4.Walker': [534, 1784], 'G.M.': [535, 1785], '1986;': [537, 1787], '5:': [538, 1788], '9-23PubMed': [539, 1789], '5.Romani': [542, 598, 1113, 1792, 1848, 2364], 'A.': [543, 545, 599, 601, 638, 640, 651, 655, 669, 673, 687, 691, 724, 726, 737, 741, 755, 759, 773, 777, 809, 813, 989, 993, 1007, 1011, 1114, 1116, 1241, 1245, 1259, 1263, 1301, 1303, 1361, 1363, 1404, 1406, 1421, 1425, 1438, 1442, 1554, 1556, 1793, 1795, 1849, 1851, 1888, 1890, 1901, 1905, 1919, 1923, 1937, 1941, 1974, 1976, 1987, 1991, 2005, 2009, 2023, 2027, 2059, 2063, 2240, 2244, 2258, 2262, 2365, 2367, 2493, 2497, 2511, 2515, 2553, 2555, 2613, 2615, 2657, 2659, 2674, 2678, 2691, 2695, 2808, 2810], 'Scarpa': [544, 600, 639, 654, 672, 690, 725, 740, 758, 776, 812, 992, 1010, 1115, 1244, 1262, 1302, 1362, 1405, 1424, 1441, 1555, 1794, 1850, 1889, 1904, 1922, 1940, 1975, 1990, 2008, 2026, 2062, 2243, 2261, 2366, 2496, 2514, 2554, 2614, 2658, 2677, 2694, 2809], 'Arch.': [546, 602, 914, 1117, 1796, 1852, 2165, 2368], 'Biochem.': [547, 603, 928, 1118, 1797, 1853, 2179, 2369], 'Biophys.': [548, 604, 929, 1119, 1798, 1854, 2180, 2370], '1992;': [549, 605, 816, 960, 1120, 1799, 1855, 2066, 2211, 2371], '298:': [550, 606, 1121, 1800, 1856, 2372], '1-12Crossref': [551, 607, 1122, 1801, 1857, 2373], '(321)': [554, 610, 1125, 1804, 1860, 2376], 'Scholar).': [556, 612, 699, 785, 1044, 1148, 1275, 1312, 1454, 1565, 1806, 1862, 1949, 2035, 2072, 2295, 2399, 2527, 2564, 2624, 2707, 2819], 'Under': [557, 1455, 1807, 2708], 'resting': [558, 1808], 'conditions,': [559, 1457, 1809, 2710], 'cellular-free': [560, 1810], 'concentration': [562, 1812], 'held': [564, 1814], 'at': [565, 1815], '0.5–0.8': [566, 1816], 'mm,': [567, 1817], 'well': [568, 1316, 1818, 2568], 'below': [569, 1819], 'its': [570, 1199, 1820, 2451], 'predicted': [571, 1821], 'electrochemical': [572, 1822], 'equilibrium,': [573, 1823], 'approximately': [575, 1825], '5': [576, 1826], 'mmMg2+': [577, 1827], 'complexed': [579, 1829], 'with': [580, 1168, 1607, 1830, 2419, 2862], 'ATP': [581, 1520, 1831, 2773], 'other': [583, 1833], 'metabolites': [584, 1834], 'In': [613, 1149, 1863, 2400, 2448], 'several': [614, 706, 1864, 1956], 'tissues': [615, 1865], 'such': [616, 1093, 1866, 2344], 'as': [617, 1094, 1492, 1867, 2345, 2745], 'heart': [618, 1868], 'liver,': [620, 1870], 'hormonal': [622, 1872], 'stimulation': [625, 1239, 1400, 1875, 2491, 2653], 'causes,': [626, 1876], 'few': [629, 1879], 'minutes,': [630, 1880], 'massive': [632, 1882], 'mobilization': [633, 1883], '(6.Romani': [637, 723, 1887, 1973], 'Nature.': [641, 727, 1891, 1977], '1990;': [642, 728, 1144, 1892, 1978, 2395], '346:': [643, 729, 1893, 1979], '841-844Crossref': [644, 730, 1894, 1980], '(148)': [647, 733, 1897, 1983], '7.Romani': [650, 736, 1900, 1986], 'Dowell': [652, 738, 1242, 1422, 1902, 1988, 2494, 2675], 'E.A.': [653, 739, 1243, 1423, 1903, 1989, 2495, 2676], 'Chem.': [658, 676, 744, 762, 996, 1025, 1248, 1266, 1428, 1445, 1908, 1926, 1994, 2012, 2247, 2276, 2500, 2518, 2681, 2698], '1991;': [659, 745, 1072, 1249, 1429, 1909, 1995, 2323, 2501, 2682], '266:': [660, 746, 1250, 1430, 1910, 1996, 2502, 2683], '24376-24384Abstract': [661, 747, 1251, 1431, 1911, 1997, 2503, 2684], 'Full': [662, 680, 748, 766, 1000, 1029, 1252, 1270, 1432, 1449, 1912, 1930, 1998, 2016, 2251, 2280, 2504, 2522, 2685, 2702], 'Text': [663, 681, 749, 767, 1001, 1030, 1253, 1271, 1433, 1450, 1913, 1931, 1999, 2017, 2252, 2281, 2505, 2523, 2686, 2703], 'PDF': [664, 682, 750, 768, 1002, 1031, 1254, 1272, 1434, 1451, 1914, 1932, 2000, 2018, 2253, 2282, 2506, 2524, 2687, 2704], '8.Romani': [668, 754, 988, 1258, 1918, 2004, 2239, 2510], 'Marfella': [670, 688, 756, 774, 810, 990, 1008, 1260, 1439, 1920, 1938, 2006, 2024, 2060, 2241, 2259, 2512, 2692], 'C.': [671, 689, 757, 775, 811, 991, 1009, 1261, 1299, 1359, 1402, 1440, 1552, 1921, 1939, 2007, 2025, 2061, 2242, 2260, 2513, 2551, 2611, 2655, 2693, 2806], '1993;': [677, 694, 763, 780, 997, 1014, 1040, 1133, 1267, 1446, 1927, 1944, 2013, 2030, 2248, 2265, 2291, 2384, 2519, 2699], '268:': [678, 764, 998, 1268, 1447, 1928, 2014, 2249, 2520, 2700], '15489-15495Abstract': [679, 765, 999, 1269, 1448, 1929, 2015, 2250, 2521, 2701], '9.Romani': [686, 772, 1006, 1936, 2022, 2257], 'Circ.': [692, 778, 1012, 1942, 2028, 2263], 'Res.': [693, 779, 930, 1013, 1943, 2029, 2181, 2264], '72:': [695, 781, 1015, 1945, 2031, 2266], '1139-1148Crossref': [696, 782, 1016, 1946, 2032, 2267], 'cytosolic-free': [701, 1951], 'undergoes': [703, 1953], 'minimal': [704, 1954], 'changes,': [705, 1955], 'intracellular': [707, 1335, 1957, 2587], 'signals': [708, 787, 1958, 2037], 'leading': [709, 1959], 'cAMP': [712, 1962], 'increase': [713, 801, 1963, 2051], 'induce': [714, 1964], 'loss': [716, 1966], '5–10%': [718, 807, 1968, 2057], 'Conversely,': [786, 2036], 'activating': [788, 2038], 'protein': [789, 1504, 2039, 2757], 'kinase': [790, 2040], 'C': [791, 2041], 'result': [792, 1494, 2042, 2747], 'accumulation': [795, 2045], 'consequent': [800, 2050], '(10.Romani': [808, 2058], 'FEBS': [814, 958, 2064, 2209], 'Lett.': [815, 959, 2065, 2210], '20:': [817, 2067], '135-140Crossref': [818, 2068], '(48)': [820, 2070], 'Scholar).These': [822], 'findings': [823, 1049, 2074, 2300], 'underscore': [824, 2075], 'operation': [826, 2077], 'very': [829, 1231, 2080, 2483], 'powerful': [830, 2081], 'machinery': [833, 2084], 'cells.': [840, 2091], 'Yet,': [841, 2092], 'transporter(s)': [844, 2095], 'has': [845, 1629, 2096, 2884], 'been': [847, 872, 973, 2098, 2123, 2224], 'isolated,': [848, 2099], 'even': [850, 2101], 'basic': [852, 2103], 'kinetic': [853, 2104], 'properties': [854, 2105], 'Mg2+cellular': [856, 2107], 'remain': [858, 2109], 'confusing': [859, 2110], 'contradictory.': [861, 2112], 'For': [862, 2113], 'example,': [863, 2114], 'dependence': [865, 2116], 'extracellular': [870, 1530, 2121, 2784], 'Na+has': [871, 2122], 'established': [873, 2124], 'invertebrate': [875, 2126], 'cells': [878, 2129], '(11.Frenkel': [879, 2130], 'E.J.': [880, 2131], 'Graziani': [881, 2132], 'M.': [882, 2133], 'Schatzmann': [883, 942, 2134, 2193], 'H.J.': [884, 943, 2135, 2194], 'Physiol.': [886, 900, 945, 1071, 1306, 1366, 1409, 1559, 2137, 2151, 2196, 2322, 2558, 2618, 2662, 2813], '(London).': [887, 901, 946, 2138, 2152, 2197], '1989;': [888, 2139], '414:': [889, 2140], '385-397Crossref': [890, 2141], '(37)': [892, 2143], '12.Gunzel': [895, 2146], 'D.': [896, 2147], 'Schlue': [897, 2148], 'N.R.': [898, 2149], '1996;': [902, 2153], '491:': [903, 2154], '595-608Crossref': [904, 2155], '(44)': [906, 2157], '13.Feray': [909, 2160], 'J.C.': [910, 1020, 2161, 2271], 'Garay': [911, 1021, 2162, 2272], 'R.': [912, 1022, 2163, 2273], "Naunyn-Schmiedeberg's": [913, 2164], 'Pharmacol.': [915, 2166], '338:': [917, 2168], '332-337Crossref': [918, 2169], '(67)': [921, 2172], '14.Gunther': [924, 2175], 'T.': [925, 955, 1036, 1129, 2176, 2206, 2287, 2380], 'Vormann': [926, 956, 2177, 2207], 'Commun.': [931, 2182], '1985;': [932, 2183], '130:': [933, 2184], '540-545Crossref': [934, 2185], '(78)': [937, 2188], '15.Ludi': [940, 2191], 'H.': [941, 2192], '390:': [948, 2199], '367-382Crossref': [949, 2200], '(43)': [951, 2202], '16.Gunther': [954, 2205], '297:': [961, 2212], '132-134Crossref': [962, 2213], '(71)': [965, 2216], 'Scholar)': [967, 1415, 2218, 2668], 'but': [968, 2219], 'Na+-independent': [969, 2220], 'have': [971, 2222], 'also': [972, 1525, 2223, 2779], 'reported': [974, 2225], 'Scholar,17.Feray': [1019, 2270], '262:': [1027, 2278], '5763-5768Abstract': [1028, 2279], '18.Gunther': [1035, 1128, 2286, 2379], 'Miner.': [1037, 1130, 2288, 2381], 'Electrolyte': [1038, 1131, 2289, 2382], 'Metab.': [1039, 1132, 2290, 2383], '19:': [1041, 1134, 2292, 2385], '259-265PubMed': [1042, 1135, 2293, 2386], 'Equally': [1045, 2296], 'contradictory': [1046, 2297], 'are': [1047, 1517, 1668, 1691, 2298, 2770, 2924, 2947], 'variable': [1051, 1089, 2302, 2340], 'Na+/Mg2+': [1052, 1548, 2303, 2802], 'stoichiometries': [1053, 2304], '19.Flatman': [1067, 2318], 'P.': [1068, 2319], 'Annu.': [1069, 2320], 'Rev.': [1070, 2321], '53:': [1073, 2324], '259-271Crossref': [1074, 2325], '(218)': [1077, 2328], 'Scholar),': [1079, 2330], 'role': [1081, 1210, 2332, 2462], 'trans-membrane': [1083, 2334], 'potential,': [1084, 2335], 'partial': [1087, 2338], 'effectiveness': [1090, 2341], 'inhibitors': [1092, 2343], '(for': [1096, 2347], 'review': [1097, 2348], 'see': [1098, 2349], 'Refs.': [1099, 2350], '1.Flatman': [1100, 2351], '20.Beyenbach': [1139, 2390], 'K.': [1140, 2391], 'Magnesium': [1141, 2392], 'Trace': [1142, 2393], 'Elem.': [1143, 2394], '9:': [1145, 2396], '233-254PubMed': [1146, 2397], 'principle,': [1150, 2401], 'discrepancies': [1152, 2403], 'could': [1153, 1355, 1488, 2404, 2607, 2741], 'accounted': [1155, 2406], 'co-existence': [1159, 2410], 'operating': [1167, 1465, 2418, 2718], 'sensitivity': [1172, 2423], 'inhibitors.': [1174, 2425], 'this': [1176, 1277, 2427, 2529, 2993], 'work': [1177, 2428], 'designed': [1179, 2430], 'putatively': [1182, 2433], 'using': [1186, 2437], 'appropriate': [1188, 2439], 'model,': [1190, 2441], 'hepatocytes.In': [1196], 'view': [1197, 2449], 'size': [1200, 2452], 'secretory': [1202, 2454], 'capacity,': [1203, 2455], 'should': [1206, 1713, 2458, 2969], 'play': [1207, 2459], 'major': [1209, 1373, 2461, 2626], 'homeostasis.': [1213, 2465], 'Recent': [1214, 2466], 'evidence': [1215, 1528, 2467, 2782], 'literature': [1218, 2470], 'demonstrates': [1219, 2471], 'perfused': [1222, 2474], 'isolated': [1225, 2477], 'large': [1232, 2484], 'amounts': [1233, 2485], '(7.Romani': [1240, 1420, 2492, 2673], 'Recently,': [1276, 2528], 'laboratory': [1278, 2530], 'able': [1280, 2532], 'successfully': [1282, 2534], 'obtain': [1283, 2535], '(LPM)1': [1288, 2540], 'across': [1293, 2545], 'hepatocyte': [1295, 1601, 2547, 2856], '(21.Cefaratti': [1298, 1401, 1551, 2550, 2654, 2805], 'Romani': [1300, 1360, 1403, 1553, 2552, 2612, 2656, 2807], 'Am.': [1304, 1364, 1407, 1557, 2556, 2616, 2660, 2811], '1998;': [1307, 1367, 1410, 1560, 2559, 2619, 2663, 2814], '275:': [1308, 1368, 1411, 1561, 2560, 2620, 2664, 2815], 'C995-C1008Crossref': [1309, 1369, 1412, 1562, 2561, 2621, 2665, 2816], 'This': [1313, 2565], 'model': [1314, 2566], 'provides': [1315, 2567], 'defined': [1317, 2569], 'controllable': [1319, 2571], 'experimental': [1320, 2572], 'conditions': [1321, 2573], 'quantitatively': [1328, 2580], 'investigated': [1329, 2581], 'absence': [1332, 1468, 2584, 2721], 'interfering': [1334, 2586], 'signaling': [1336, 1522, 2588, 2775], 'organelles.': [1341, 2593], 'membranes,': [1345, 2597], 'we': [1346, 2598], 'recently': [1347, 2599], 'found': [1348, 2600], 'extravesicular': [1351, 1390, 2603, 2643], 'Ca2+': [1354, 1393, 1533, 2606, 2646, 2787], 'mobilize': [1356, 2608], 'intravesicular': [1357, 1384, 2609, 2637], 'Mg2+(21.Cefaratti': [1358, 2610], 'Scholar).A': [1372], 'difference': [1374, 2627], 'they': [1382, 1516, 2635, 2769], 'presence': [1388, 1478, 1545, 2641, 2731, 2799], 'alone,': [1394, 2647], 'without': [1395, 2648], 'need': [1397, 2650], 'intact': [1418, 2671], 'Scholar,8.Romani': [1437, 2690], 'appears': [1461, 1508, 2714, 2761], '"uncoupled"': [1462, 2715], 'maximally': [1464, 2717], 'stimulatory': [1470, 2723], 'signals.': [1472, 2725], 'One': [1473, 2726], 'intriguing': [1474, 2727], 'possibility': [1475, 1635, 2728, 2890], 'physiological': [1483, 2736], '"break"': [1484, 2737], 'Mg2+transport,': [1486, 2739], 'transiently': [1490, 2743], 'removed': [1491, 2744], 'pathways.': [1499, 2752, 2776], 'Such': [1500, 1710, 2753, 2966], 'break': [1502, 2755], '(i.e.': [1503, 2756], 'phosphorylation': [1505, 2758], 'dephosphorylation)': [1507, 2760], 'absent': [1511, 2764], 'LPM': [1513, 2766], 'probably': [1514, 2767], 'devoid': [1518, 2771], 'pathways.Those': [1523], 'studies': [1524, 2778], 'provided': [1526, 2780], 'direct': [1527, 2781], 'elicited': [1534, 2788], 'larger': [1536, 2790], 'Mg2+efflux': [1537, 2791], 'than': [1538, 2792], 'alone': [1541, 2795], 'suggested': [1543, 2797], 'Ca2+/Mg2+transporters': [1550, 2804], 'Unfortunately,': [1566, 2820], 'both': [1567, 1694, 2821, 2950], 'putative': [1568, 2822], 'seemed': [1570, 2824], 'same': [1576, 1592, 2830, 2846], 'inhibitor.': [1577, 2831], 'Additionally,': [1578, 2832], 'clear': [1582, 2836], 'whether': [1583, 2837], 'were': [1588, 2842], 'localized': [1589, 1692, 2843, 2948], 'vesicle': [1593, 2847], 'populations': [1598, 1639, 2852, 2894], 'vesicles.The': [1600], 'highly': [1604, 2859], 'polarized': [1605, 2860], 'differential': [1608, 2863], 'enzymes': [1611, 2866], 'main': [1617, 2872], 'domains,': [1619, 2874], 'membrane.': [1625, 2880], 'present': [1627, 2882], 'now': [1630, 2885], 'taken': [1631, 2886], 'advantage': [1632, 2887], 'obtaining': [1637, 2892], 'properly': [1643, 2898], 'oriented': [1644, 2899], 'comprised': [1647, 2902], 'mostly': [1648, 2903], 'domains.The': [1656], 'data': [1657, 1683, 2913, 2939], 'presented': [1658, 2914], 'here': [1659, 2915], 'demonstrate': [1660, 2916], 'Na+-': [1663, 2919], 'dependent': [1664, 2920], 'Ca2+-dependent': [1666, 2922], 'Mg2+transporters': [1667, 1722, 2923, 2978], 'terms': [1671, 2927], 'operation.': [1681, 2937], 'indicate': [1684, 2940], 'distinguishable': [1687, 2943], 'Na+-dependent': [1688, 2944], 'Mg2+exchange': [1689, 2945], 'operates': [1704, 2960], 'domain.': [1709, 2965], 'finding': [1712, 2968], 'primary': [1716, 2972], 'importance': [1717, 2973], 'kinetically': [1719, 2975], 'characterize': [1720, 2976], 'individual': [1721, 2977], 'identify': [1726, 2982], 'them.': [1727, 2983], 'These': [2073], 'hepatocytes.': [2447], 'A': [2625], 'Those': [2777], 'vesicles.': [2854], 'domains.': [2911], 'We': [2984], 'thank': [2985], 'Drs.': [2986], 'Meredith': [2987], 'Bond': [2988], 'Ulrich': [2990], 'Hopfer': [2991], 'department': [2994], 'valuable': [2996], 'scientific': [2997], 'discussion.': [2998]}, 'cited_by_api_url': 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