Abstract: (3-Pyridinyl)alkanoic acids substituted at the 4-position with an (arylsulfonamido)alkyl group were synthesized and found to behave as platelet thromboxane receptor antagonists (TxRAs) and thromboxane synthase inhibitors (TxSIs). The compounds behaved as agonists at the vascular receptor for thromboxane A2.
Publication Year: 1992
Publication Date: 1992-12-01
Language: en
Type: article
Indexed In: ['crossref']
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Cited By Count: 2
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