Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2029592985', 'doi': 'https://doi.org/10.1002/cne.22273', 'title': 'Differential distribution of tight junction proteins suggests a role for tanycytes in blood‐hypothalamus barrier regulation in the adult mouse brain', 'display_name': 'Differential distribution of tight junction proteins suggests a role for tanycytes in blood‐hypothalamus barrier regulation in the adult mouse brain', 'publication_year': 2010, 'publication_date': '2010-02-01', 'ids': {'openalex': 'https://openalex.org/W2029592985', 'doi': 'https://doi.org/10.1002/cne.22273', 'mag': '2029592985', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/20127760', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/2892518'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/cne.22273', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4210186231', 'display_name': 'The Journal of Comparative Neurology', 'issn_l': '0021-9967', 'issn': ['0021-9967', '1096-9861'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892518', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5091528330', 'display_name': 'Amandine Mullier', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210098046', 'display_name': 'Centre de Recherche Jean Pierre Aubert', 'ror': 'https://ror.org/00x76wb44', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I154526488', 'https://openalex.org/I4210098046']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}, {'id': 'https://openalex.org/I4210114331', 'display_name': 'Predict (France)', 'ror': 'https://ror.org/02h0hx086', 'country_code': 'FR', 'type': 'company', 'lineage': ['https://openalex.org/I4210114331']}, {'id': 'https://openalex.org/I59807433', 'display_name': 'Université Lille Nord de France', 'ror': 'https://ror.org/03btvgn05', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I59807433']}], 'countries': ['FR'], 'is_corresponding': True, 'raw_author_name': 'Amandine Mullier', 'raw_affiliation_strings': ['Institut de Médecine Prédictive et Recherche Thérapeutique, Faculté de Médecine, Université Lille Nord de France, Place de Verdun, 59046 Lille Cedex, France', 'Jean-Pierre Aubert Research Center, Development and Plasticity of the Postnatal Brain, Inserm U837, 59045 Lille Cedex, France'], 'affiliations': [{'raw_affiliation_string': 'Jean-Pierre Aubert Research Center, Development and Plasticity of the Postnatal Brain, Inserm U837, 59045 Lille Cedex, France', 'institution_ids': ['https://openalex.org/I4210098046', 'https://openalex.org/I154526488']}, {'raw_affiliation_string': 'Institut de Médecine Prédictive et Recherche Thérapeutique, Faculté de Médecine, Université Lille Nord de France, Place de Verdun, 59046 Lille Cedex, France', 'institution_ids': ['https://openalex.org/I4210114331', 'https://openalex.org/I59807433']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5060733104', 'display_name': 'Sébastien Bouret', 'orcid': 'https://orcid.org/0000-0003-2279-6161'}, 'institutions': [{'id': 'https://openalex.org/I1336910626', 'display_name': "Children's Hospital of Los Angeles", 'ror': 'https://ror.org/00412ts95', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1336910626']}, {'id': 'https://openalex.org/I4210114331', 'display_name': 'Predict (France)', 'ror': 'https://ror.org/02h0hx086', 'country_code': 'FR', 'type': 'company', 'lineage': ['https://openalex.org/I4210114331']}, {'id': 'https://openalex.org/I59807433', 'display_name': 'Université Lille Nord de France', 'ror': 'https://ror.org/03btvgn05', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I59807433']}, {'id': 'https://openalex.org/I4210098046', 'display_name': 'Centre de Recherche Jean Pierre Aubert', 'ror': 'https://ror.org/00x76wb44', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I154526488', 'https://openalex.org/I4210098046']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}, {'id': 'https://openalex.org/I1174212', 'display_name': 'University of Southern California', 'ror': 'https://ror.org/03taz7m60', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I1174212']}], 'countries': ['FR', 'US'], 'is_corresponding': True, 'raw_author_name': 'Sebastien G. Bouret', 'raw_affiliation_strings': ['Institut de Médecine Prédictive et Recherche Thérapeutique, Faculté de Médecine, Université Lille Nord de France, Place de Verdun, 59046 Lille Cedex, France', 'Jean-Pierre Aubert Research Center, Development and Plasticity of the Postnatal Brain, Inserm U837, 59045 Lille Cedex, France', "The Saban Research Institute, Neuroscience Program, Children's Hospital of Los Angeles, University of Southern California, Los Angeles, California 90027"], 'affiliations': [{'raw_affiliation_string': "The Saban Research Institute, Neuroscience Program, Children's Hospital of Los Angeles, University of Southern California, Los Angeles, California 90027", 'institution_ids': ['https://openalex.org/I1336910626', 'https://openalex.org/I1174212']}, {'raw_affiliation_string': 'Institut de Médecine Prédictive et Recherche Thérapeutique, Faculté de Médecine, Université Lille Nord de France, Place de Verdun, 59046 Lille Cedex, France', 'institution_ids': ['https://openalex.org/I4210114331', 'https://openalex.org/I59807433']}, {'raw_affiliation_string': 'Jean-Pierre Aubert Research Center, Development and Plasticity of the Postnatal Brain, Inserm U837, 59045 Lille Cedex, France', 'institution_ids': ['https://openalex.org/I4210098046', 'https://openalex.org/I154526488']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5083058332', 'display_name': 'Vincent Prévot', 'orcid': 'https://orcid.org/0000-0001-7185-3615'}, 'institutions': [{'id': 'https://openalex.org/I4210114331', 'display_name': 'Predict (France)', 'ror': 'https://ror.org/02h0hx086', 'country_code': 'FR', 'type': 'company', 'lineage': ['https://openalex.org/I4210114331']}, {'id': 'https://openalex.org/I59807433', 'display_name': 'Université Lille Nord de France', 'ror': 'https://ror.org/03btvgn05', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I59807433']}, {'id': 'https://openalex.org/I4210098046', 'display_name': 'Centre de Recherche Jean Pierre Aubert', 'ror': 'https://ror.org/00x76wb44', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I154526488', 'https://openalex.org/I4210098046']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}], 'countries': ['FR'], 'is_corresponding': True, 'raw_author_name': 'Vincent Prevot', 'raw_affiliation_strings': ['Institut de Médecine Prédictive et Recherche Thérapeutique, Faculté de Médecine, Université Lille Nord de France, Place de Verdun, 59046 Lille Cedex, France', 'Jean-Pierre Aubert Research Center, Development and Plasticity of the Postnatal Brain, Inserm U837, 59045 Lille Cedex, France'], 'affiliations': [{'raw_affiliation_string': 'Institut de Médecine Prédictive et Recherche Thérapeutique, Faculté de Médecine, Université Lille Nord de France, Place de Verdun, 59046 Lille Cedex, France', 'institution_ids': ['https://openalex.org/I4210114331', 'https://openalex.org/I59807433']}, {'raw_affiliation_string': 'Jean-Pierre Aubert Research Center, Development and Plasticity of the Postnatal Brain, Inserm U837, 59045 Lille Cedex, France', 'institution_ids': ['https://openalex.org/I4210098046', 'https://openalex.org/I154526488']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5052015791', 'display_name': 'Bénédicte Dehouck', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210114331', 'display_name': 'Predict (France)', 'ror': 'https://ror.org/02h0hx086', 'country_code': 'FR', 'type': 'company', 'lineage': ['https://openalex.org/I4210114331']}, {'id': 'https://openalex.org/I59807433', 'display_name': 'Université Lille Nord de France', 'ror': 'https://ror.org/03btvgn05', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I59807433']}, {'id': 'https://openalex.org/I4210098046', 'display_name': 'Centre de Recherche Jean Pierre Aubert', 'ror': 'https://ror.org/00x76wb44', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I154526488', 'https://openalex.org/I4210098046']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}], 'countries': ['FR'], 'is_corresponding': True, 'raw_author_name': 'Bénédicte Dehouck', 'raw_affiliation_strings': ['Institut de Médecine Prédictive et Recherche Thérapeutique, Faculté de Médecine, Université Lille Nord de France, Place de Verdun, 59046 Lille Cedex, France', 'Jean-Pierre Aubert Research Center, Development and Plasticity of the Postnatal Brain, Inserm U837, 59045 Lille Cedex, France'], 'affiliations': [{'raw_affiliation_string': 'Institut de Médecine Prédictive et Recherche Thérapeutique, Faculté de Médecine, Université Lille Nord de France, Place de Verdun, 59046 Lille Cedex, France', 'institution_ids': ['https://openalex.org/I4210114331', 'https://openalex.org/I59807433']}, {'raw_affiliation_string': 'Jean-Pierre Aubert Research Center, Development and Plasticity of the Postnatal Brain, Inserm U837, 59045 Lille Cedex, France', 'institution_ids': ['https://openalex.org/I4210098046', 'https://openalex.org/I154526488']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 6, 'corresponding_author_ids': ['https://openalex.org/A5091528330', 'https://openalex.org/A5060733104', 'https://openalex.org/A5083058332', 'https://openalex.org/A5052015791'], 'corresponding_institution_ids': ['https://openalex.org/I4210098046', 'https://openalex.org/I154526488', 'https://openalex.org/I4210114331', 'https://openalex.org/I59807433', 'https://openalex.org/I1336910626', 'https://openalex.org/I4210114331', 'https://openalex.org/I59807433', 'https://openalex.org/I4210098046', 'https://openalex.org/I154526488', 'https://openalex.org/I1174212', 'https://openalex.org/I4210114331', 'https://openalex.org/I59807433', 'https://openalex.org/I4210098046', 'https://openalex.org/I154526488', 'https://openalex.org/I4210114331', 'https://openalex.org/I59807433', 'https://openalex.org/I4210098046', 'https://openalex.org/I154526488'], 'apc_list': None, 'apc_paid': None, 'fwci': 12.735, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 273, 'citation_normalized_percentile': {'value': 0.999767, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '518', 'issue': '7', 'first_page': '943', 'last_page': '962'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11872', 'display_name': 'Blood-Brain Barrier and Neurovascular Interactions', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2808', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11872', 'display_name': 'Blood-Brain Barrier and Neurovascular Interactions', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2808', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11184', 'display_name': 'Neonatal Brain Injury and Developmental Consequences', 'score': 0.9941, 'subfield': {'id': 'https://openalex.org/subfields/2735', 'display_name': 'Pediatrics, Perinatology and Child Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10489', 'display_name': 'Neuroendocrine Regulation of Appetite and Body Weight', 'score': 0.9894, 'subfield': {'id': 'https://openalex.org/subfields/2807', 'display_name': 'Endocrine and Autonomic Systems'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/median-eminence', 'display_name': 'Median eminence', 'score': 0.9693288}, {'id': 'https://openalex.org/keywords/ependymal-cell', 'display_name': 'Ependymal Cell', 'score': 0.7907275}, {'id': 'https://openalex.org/keywords/circumventricular-organs', 'display_name': 'Circumventricular organs', 'score': 0.7771499}, {'id': 'https://openalex.org/keywords/ganglionic-eminence', 'display_name': 'Ganglionic eminence', 'score': 0.699122}, {'id': 'https://openalex.org/keywords/occludin', 'display_name': 'Occludin', 'score': 0.55662787}, {'id': 'https://openalex.org/keywords/claudin', 'display_name': 'Claudin', 'score': 0.47841367}, {'id': 'https://openalex.org/keywords/tight-junctions', 'display_name': 'Tight Junctions', 'score': 0.476266}], 'concepts': [{'id': 'https://openalex.org/C2779067335', 'wikidata': 'https://www.wikidata.org/wiki/Q1337712', 'display_name': 'Median eminence', 'level': 3, 'score': 0.9693288}, {'id': 'https://openalex.org/C2778458369', 'wikidata': 'https://www.wikidata.org/wiki/Q253246', 'display_name': 'Arcuate nucleus', 'level': 3, 'score': 0.79567397}, {'id': 'https://openalex.org/C2909073510', 'wikidata': 'https://www.wikidata.org/wiki/Q1134467', 'display_name': 'Ependymal Cell', 'level': 3, 'score': 0.7907275}, {'id': 'https://openalex.org/C2777619780', 'wikidata': 'https://www.wikidata.org/wiki/Q205925', 'display_name': 'Circumventricular organs', 'level': 3, 'score': 0.7771499}, {'id': 'https://openalex.org/C2780597806', 'wikidata': 'https://www.wikidata.org/wiki/Q4133185', 'display_name': 'Ganglionic eminence', 'level': 4, 'score': 0.699122}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.67205936}, {'id': 'https://openalex.org/C177779419', 'wikidata': 'https://www.wikidata.org/wiki/Q1053832', 'display_name': 'Tight junction', 'level': 2, 'score': 0.6601497}, {'id': 'https://openalex.org/C2781171461', 'wikidata': 'https://www.wikidata.org/wiki/Q662322', 'display_name': 'Third ventricle', 'level': 2, 'score': 0.6443446}, {'id': 'https://openalex.org/C2777003273', 'wikidata': 'https://www.wikidata.org/wiki/Q164386', 'display_name': 'Hypothalamus', 'level': 2, 'score': 0.61773473}, {'id': 'https://openalex.org/C2775962179', 'wikidata': 'https://www.wikidata.org/wiki/Q2013337', 'display_name': 'Occludin', 'level': 3, 'score': 0.55662787}, {'id': 'https://openalex.org/C2778402981', 'wikidata': 'https://www.wikidata.org/wiki/Q221694', 'display_name': 'Blood–brain barrier', 'level': 3, 'score': 0.5251151}, {'id': 'https://openalex.org/C51872919', 'wikidata': 'https://www.wikidata.org/wiki/Q420863', 'display_name': 'Claudin', 'level': 3, 'score': 0.47841367}, {'id': 'https://openalex.org/C2780723820', 'wikidata': 'https://www.wikidata.org/wiki/Q1934178', 'display_name': 'Nucleus', 'level': 2, 'score': 0.45149183}, {'id': 'https://openalex.org/C2776538271', 'wikidata': 'https://www.wikidata.org/wiki/Q926250', 'display_name': 'Choroid plexus', 'level': 3, 'score': 0.4430005}, {'id': 'https://openalex.org/C105702510', 'wikidata': 'https://www.wikidata.org/wiki/Q514', 'display_name': 'Anatomy', 'level': 1, 'score': 0.4299274}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.3837198}, {'id': 'https://openalex.org/C169760540', 'wikidata': 'https://www.wikidata.org/wiki/Q207011', 'display_name': 'Neuroscience', 'level': 1, 'score': 0.36294076}, {'id': 'https://openalex.org/C529278444', 'wikidata': 'https://www.wikidata.org/wiki/Q47273', 'display_name': 'Central nervous system', 'level': 2, 'score': 0.25643754}, {'id': 'https://openalex.org/C533869091', 'wikidata': 'https://www.wikidata.org/wiki/Q75855', 'display_name': 'Cerebrum', 'level': 3, 'score': 0.07827383}], 'mesh': [{'descriptor_ui': 'D001812', 'descriptor_name': 'Blood-Brain Barrier', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': True}, {'descriptor_ui': 'D001812', 'descriptor_name': 'Blood-Brain Barrier', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D007031', 'descriptor_name': 'Hypothalamus', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': True}, {'descriptor_ui': 'D007031', 'descriptor_name': 'Hypothalamus', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D008473', 'descriptor_name': 'Median Eminence', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D008565', 'descriptor_name': 'Membrane Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D019108', 'descriptor_name': 'Tight Junctions', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001812', 'descriptor_name': 'Blood-Brain Barrier', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D062445', 'descriptor_name': 'Claudin-1', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D062507', 'descriptor_name': 'Claudin-5', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007031', 'descriptor_name': 'Hypothalamus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007150', 'descriptor_name': 'Immunohistochemistry', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008473', 'descriptor_name': 'Median Eminence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008473', 'descriptor_name': 'Median Eminence', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D008565', 'descriptor_name': 'Membrane Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008810', 'descriptor_name': 'Mice, Inbred C57BL', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D062793', 'descriptor_name': 'Occludin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010750', 'descriptor_name': 'Phosphoproteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010750', 'descriptor_name': 'Phosphoproteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D019108', 'descriptor_name': 'Tight Junctions', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D062826', 'descriptor_name': 'Zonula Occludens-1 Protein', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 8, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/cne.22273', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4210186231', 'display_name': 'The Journal of Comparative Neurology', 'issn_l': '0021-9967', 'issn': ['0021-9967', '1096-9861'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892518', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc2892518', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.hal.inserm.fr/inserm-00487090/file/JCN-09-0237.R4.pdf', 'pdf_url': 'https://www.hal.inserm.fr/inserm-00487090/file/JCN-09-0237.R4.pdf', 'source': {'id': 'https://openalex.org/S4306402512', 'display_name': 'HAL (Le Centre pour la Communication Scientifique Directe)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1294671590', 'host_organization_name': 'Centre National de la Recherche Scientifique', 'host_organization_lineage': ['https://openalex.org/I1294671590'], 'host_organization_lineage_names': ['Centre National de la Recherche Scientifique'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.hal.inserm.fr/inserm-00487090', 'pdf_url': 'https://inserm.hal.science/inserm-00487090/document', 'source': {'id': 'https://openalex.org/S4306402512', 'display_name': 'HAL (Le Centre pour la Communication Scientifique Directe)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1294671590', 'host_organization_name': 'Centre National de la Recherche Scientifique', 'host_organization_lineage': ['https://openalex.org/I1294671590'], 'host_organization_lineage_names': ['Centre National de la Recherche Scientifique'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.hal.inserm.fr/inserm-00487090/document', 'pdf_url': 'https://www.hal.inserm.fr/inserm-00487090/document', 'source': {'id': 'https://openalex.org/S4306402512', 'display_name': 'HAL (Le Centre pour la Communication Scientifique Directe)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1294671590', 'host_organization_name': 'Centre National de la Recherche Scientifique', 'host_organization_lineage': ['https://openalex.org/I1294671590'], 'host_organization_lineage_names': ['Centre National de la Recherche Scientifique'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.hal.inserm.fr/inserm-00487090/file/inserm-00487090_edited.pdf', 'pdf_url': 'https://www.hal.inserm.fr/inserm-00487090/file/inserm-00487090_edited.pdf', 'source': {'id': 'https://openalex.org/S4306402512', 'display_name': 'HAL (Le Centre pour la Communication Scientifique Directe)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1294671590', 'host_organization_name': 'Centre National de la Recherche Scientifique', 'host_organization_lineage': ['https://openalex.org/I1294671590'], 'host_organization_lineage_names': ['Centre National de la Recherche Scientifique'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/20127760', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892518', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 62, 'referenced_works': ['https://openalex.org/W1004315509', 'https://openalex.org/W1553662603', 'https://openalex.org/W1554042779', 'https://openalex.org/W1569944469', 'https://openalex.org/W1638810975', 'https://openalex.org/W1728099308', 'https://openalex.org/W1876616931', 'https://openalex.org/W1968329147', 'https://openalex.org/W1969597097', 'https://openalex.org/W1980127660', 'https://openalex.org/W1982252520', 'https://openalex.org/W1982846560', 'https://openalex.org/W1984202851', 'https://openalex.org/W1986658803', 'https://openalex.org/W1988551550', 'https://openalex.org/W1997494318', 'https://openalex.org/W2005262731', 'https://openalex.org/W2008661951', 'https://openalex.org/W2010844149', 'https://openalex.org/W2017163181', 'https://openalex.org/W2018000241', 'https://openalex.org/W2021341827', 'https://openalex.org/W2022726058', 'https://openalex.org/W2023532283', 'https://openalex.org/W2025476539', 'https://openalex.org/W2031759209', 'https://openalex.org/W2031832348', 'https://openalex.org/W2033446860', 'https://openalex.org/W2034626424', 'https://openalex.org/W2038126976', 'https://openalex.org/W2039176792', 'https://openalex.org/W2039585707', 'https://openalex.org/W2045272143', 'https://openalex.org/W2050912412', 'https://openalex.org/W2050998289', 'https://openalex.org/W2052577868', 'https://openalex.org/W2056959490', 'https://openalex.org/W2060298694', 'https://openalex.org/W2065886495', 'https://openalex.org/W2070141915', 'https://openalex.org/W2070225650', 'https://openalex.org/W2075564085', 'https://openalex.org/W2075711816', 'https://openalex.org/W2078605292', 'https://openalex.org/W2082167334', 'https://openalex.org/W2087666006', 'https://openalex.org/W2100232740', 'https://openalex.org/W2103831817', 'https://openalex.org/W2104520647', 'https://openalex.org/W2104567497', 'https://openalex.org/W2105535336', 'https://openalex.org/W2114895224', 'https://openalex.org/W2132024007', 'https://openalex.org/W2143776806', 'https://openalex.org/W2155957079', 'https://openalex.org/W2159588837', 'https://openalex.org/W2406287208', 'https://openalex.org/W2614988120', 'https://openalex.org/W2754032574', 'https://openalex.org/W3007487704', 'https://openalex.org/W4290433844', 'https://openalex.org/W567584223'], 'related_works': ['https://openalex.org/W4251578979', 'https://openalex.org/W4246723061', 'https://openalex.org/W2883493233', 'https://openalex.org/W2735859817', 'https://openalex.org/W2075711816', 'https://openalex.org/W2070999168', 'https://openalex.org/W2057966943', 'https://openalex.org/W2029592985', 'https://openalex.org/W1981272224', 'https://openalex.org/W1941456052'], 'abstract_inverted_index': {'Abstract': [0], 'The': [1, 51], 'median': [2, 52, 119, 131, 221], 'eminence': [3, 53, 120, 132, 222], 'is': [4, 13, 82], 'one': [5, 75], 'of': [6, 48, 66, 76, 79, 109, 129, 158, 166, 177, 193, 210, 219, 238, 255], 'the': [7, 16, 21, 27, 64, 67, 77, 91, 97, 107, 114, 118, 130, 155, 159, 163, 167, 172, 175, 178, 217, 220, 236, 239], 'seven': [8], 'so‐called': [9], 'circumventricular': [10], 'organs.': [11], 'It': [12, 70], 'located': [14, 234], 'in': [15, 90, 113, 121, 259], 'basal': [17], 'hypothalamus,': [18], 'ventral': [19, 164], 'to': [20, 26, 83, 105], 'third': [22, 68, 168], 'ventricle': [23], 'and': [24, 38, 136, 139, 186, 196], 'adjacent': [25], 'arcuate': [28, 179, 240], 'nucleus.': [29], 'This': [30], 'structure': [31], 'characteristically': [32], 'contains': [33, 55], 'a': [34, 40, 45, 85, 151, 189, 243, 251], 'rich': [35], 'capillary': [36, 93], 'plexus': [37], 'features': [39], 'fenestrated': [41], 'endothelium,': [42], 'making': [43], 'it': [44], 'direct': [46], 'target': [47], 'blood‐borne': [49], 'molecules.': [50], 'also': [54], 'highly': [56], 'specialized': [57], 'ependymal': [58], 'cells': [59, 81, 115], 'called': [60], 'tanycytes,': [61, 261], 'which': [62, 262], 'line': [63, 162], 'floor': [65], 'ventricle.': [69, 169], 'has': [71], 'been': [72], 'hypothesized': [73], 'that': [74, 87, 116, 127, 161, 215], 'functions': [78], 'these': [80, 146, 201], 'create': [84], 'barrier': [86, 268], 'prevents': [88], 'substances': [89], 'portal': [92], 'spaces': [94], 'from': [95], 'entering': [96], 'brain.': [98], 'In': [99, 170, 246], 'this': [100, 248], 'paper,': [101], 'we': [102], 'utilize': [103], 'immunohistochemistry': [104], 'study': [106, 249], 'expression': [108, 191, 253], 'tight': [110, 230, 256], 'junction': [111, 257], 'proteins': [112, 258], 'compose': [117], 'adult': [122], 'mice.': [123], 'Our': [124], 'results': [125], 'indicate': [126], 'tanycytes': [128, 160, 173, 218, 233], 'express': [133, 183], 'occludin,': [134, 194], 'ZO‐1,': [135, 195], 'claudin': [137, 143, 184, 197], '1': [138, 185], '5,': [140], 'but': [141], 'not': [142, 182], '3.': [144], 'Remarkably,': [145], 'molecules': [147], 'are': [148, 223], 'organized': [149], 'as': [150], 'continuous': [152], 'belt': [153], 'around': [154], 'cell': [156], 'bodies': [157], 'part': [165], 'contrast,': [171], 'at': [174, 225, 235], 'periphery': [176], 'nucleus': [180, 241], 'do': [181], 'instead': [187], 'exhibit': [188], 'disorganized': [190], 'pattern': [192, 254], '5.': [198], 'Consistent': [199], 'with': [200], 'observations,': [202], 'permeability': [203], 'studies': [204], 'using': [205], 'peripheral': [206], 'or': [207], 'central': [208], 'injections': [209], 'Evans': [211], 'blue': [212], 'dye': [213], 'show': [214], 'only': [216], 'joined': [224], 'their': [226, 267], 'apices': [227], 'by': [228], 'functional': [229], 'junctions,': [231], 'whereas': [232], 'level': [237], 'form': [242], 'permeable': [244], 'layer.': [245], 'conclusion,': [247], 'reveals': [250], 'unique': [252], 'hypothalamic': [260], 'yields': [263], 'new': [264], 'insights': [265], 'into': [266], 'properties.': [269], 'J.': [270], 'Comp.': [271], 'Neurol.': [272], '518:943–962,': [273], '2010.': [274], '©': [275], '2009': [276], 'Wiley‐Liss,': [277], 'Inc.': [278]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2029592985', 'counts_by_year': [{'year': 2024, 'cited_by_count': 12}, {'year': 2023, 'cited_by_count': 21}, {'year': 2022, 'cited_by_count': 18}, {'year': 2021, 'cited_by_count': 25}, {'year': 2020, 'cited_by_count': 24}, {'year': 2019, 'cited_by_count': 16}, {'year': 2018, 'cited_by_count': 20}, {'year': 2017, 'cited_by_count': 26}, {'year': 2016, 'cited_by_count': 9}, {'year': 2015, 'cited_by_count': 24}, {'year': 2014, 'cited_by_count': 24}, {'year': 2013, 'cited_by_count': 16}, {'year': 2012, 'cited_by_count': 12}], 'updated_date': '2024-09-15T22:14:13.852065', 'created_date': '2016-06-24'}