Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1941456052', 'doi': 'https://doi.org/10.1002/cne.23355', 'title': 'Tanycyte‐like cells form a blood–cerebrospinal fluid barrier in the circumventricular organs of the mouse brain', 'display_name': 'Tanycyte‐like cells form a blood–cerebrospinal fluid barrier in the circumventricular organs of the mouse brain', 'publication_year': 2013, 'publication_date': '2013-05-04', 'ids': {'openalex': 'https://openalex.org/W1941456052', 'doi': 'https://doi.org/10.1002/cne.23355', 'mag': '1941456052', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/23649873', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/3973970'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/cne.23355', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4210186231', 'display_name': 'The Journal of Comparative Neurology', 'issn_l': '0021-9967', 'issn': ['0021-9967', '1096-9861'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://europepmc.org/articles/pmc3973970?pdf=render', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5025844013', 'display_name': 'Fanny Langlet', 'orcid': 'https://orcid.org/0000-0003-0021-0422'}, 'institutions': [{'id': 'https://openalex.org/I2279609970', 'display_name': 'Université de Lille', 'ror': 'https://ror.org/02kzqn938', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I2279609970']}, {'id': 'https://openalex.org/I4210098046', 'display_name': 'Centre de Recherche Jean Pierre Aubert', 'ror': 'https://ror.org/00x76wb44', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I154526488', 'https://openalex.org/I4210098046']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}, {'id': 'https://openalex.org/I59807433', 'display_name': 'Université Lille Nord de France', 'ror': 'https://ror.org/03btvgn05', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I59807433']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Fanny Langlet', 'raw_affiliation_strings': ['Laboratory of Development and Plasticity of the Postnatal Brain, Jean-Pierre Aubert Research Centre (JPARC), Inserm U837, University of Lille 2, Lille, 59000, France', 'NEUROBESE International Associated Laboratory, 59045 Lille cedex, France', 'Univ Lille Nord de France, School of Medicine, 59046 Lille cedex, France'], 'affiliations': [{'raw_affiliation_string': 'NEUROBESE International Associated Laboratory, 59045 Lille cedex, France', 'institution_ids': []}, {'raw_affiliation_string': 'Univ Lille Nord de France, School of Medicine, 59046 Lille cedex, France', 'institution_ids': ['https://openalex.org/I2279609970', 'https://openalex.org/I59807433']}, {'raw_affiliation_string': 'Laboratory of Development and Plasticity of the Postnatal Brain, Jean-Pierre Aubert Research Centre (JPARC), Inserm U837, University of Lille 2, Lille, 59000, France', 'institution_ids': ['https://openalex.org/I4210098046', 'https://openalex.org/I2279609970', 'https://openalex.org/I154526488']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5091528330', 'display_name': 'Amandine Mullier', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210098046', 'display_name': 'Centre de Recherche Jean Pierre Aubert', 'ror': 'https://ror.org/00x76wb44', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I154526488', 'https://openalex.org/I4210098046']}, {'id': 'https://openalex.org/I2279609970', 'display_name': 'Université de Lille', 'ror': 'https://ror.org/02kzqn938', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I2279609970']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}, {'id': 'https://openalex.org/I59807433', 'display_name': 'Université Lille Nord de France', 'ror': 'https://ror.org/03btvgn05', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I59807433']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Amandine Mullier', 'raw_affiliation_strings': ['Laboratory of Development and Plasticity of the Postnatal Brain, Jean-Pierre Aubert Research Centre (JPARC), Inserm U837, University of Lille 2, Lille, 59000, France', 'NEUROBESE International Associated Laboratory, 59045 Lille cedex, France', 'Univ Lille Nord de France, School of Medicine, 59046 Lille cedex, France'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Development and Plasticity of the Postnatal Brain, Jean-Pierre Aubert Research Centre (JPARC), Inserm U837, University of Lille 2, Lille, 59000, France', 'institution_ids': ['https://openalex.org/I4210098046', 'https://openalex.org/I2279609970', 'https://openalex.org/I154526488']}, {'raw_affiliation_string': 'NEUROBESE International Associated Laboratory, 59045 Lille cedex, France', 'institution_ids': []}, {'raw_affiliation_string': 'Univ Lille Nord de France, School of Medicine, 59046 Lille cedex, France', 'institution_ids': ['https://openalex.org/I59807433', 'https://openalex.org/I2279609970']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5060733104', 'display_name': 'Sébastien Bouret', 'orcid': 'https://orcid.org/0000-0003-2279-6161'}, 'institutions': [{'id': 'https://openalex.org/I4210098046', 'display_name': 'Centre de Recherche Jean Pierre Aubert', 'ror': 'https://ror.org/00x76wb44', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I154526488', 'https://openalex.org/I4210098046']}, {'id': 'https://openalex.org/I2279609970', 'display_name': 'Université de Lille', 'ror': 'https://ror.org/02kzqn938', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I2279609970']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}, {'id': 'https://openalex.org/I1174212', 'display_name': 'University of Southern California', 'ror': 'https://ror.org/03taz7m60', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I1174212']}, {'id': 'https://openalex.org/I59807433', 'display_name': 'Université Lille Nord de France', 'ror': 'https://ror.org/03btvgn05', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I59807433']}, {'id': 'https://openalex.org/I1336910626', 'display_name': "Children's Hospital of Los Angeles", 'ror': 'https://ror.org/00412ts95', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1336910626']}], 'countries': ['FR', 'US'], 'is_corresponding': False, 'raw_author_name': 'Sebastien G. Bouret', 'raw_affiliation_strings': ['Laboratory of Development and Plasticity of the Postnatal Brain, Jean-Pierre Aubert Research Centre (JPARC), Inserm U837, University of Lille 2, Lille, 59000, France', 'NEUROBESE International Associated Laboratory, 59045 Lille cedex, France', 'Neuroscience Program, Saban Research Institute, Childrens Hospital Los Angeles, University of Southern California, Los Angeles, CA, USA', 'Univ Lille Nord de France, School of Medicine, 59046 Lille cedex, France'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Development and Plasticity of the Postnatal Brain, Jean-Pierre Aubert Research Centre (JPARC), Inserm U837, University of Lille 2, Lille, 59000, France', 'institution_ids': ['https://openalex.org/I4210098046', 'https://openalex.org/I2279609970', 'https://openalex.org/I154526488']}, {'raw_affiliation_string': 'NEUROBESE International Associated Laboratory, 59045 Lille cedex, France', 'institution_ids': []}, {'raw_affiliation_string': 'Neuroscience Program, Saban Research Institute, Childrens Hospital Los Angeles, University of Southern California, Los Angeles, CA, USA', 'institution_ids': ['https://openalex.org/I1174212', 'https://openalex.org/I1336910626']}, {'raw_affiliation_string': 'Univ Lille Nord de France, School of Medicine, 59046 Lille cedex, France', 'institution_ids': ['https://openalex.org/I59807433', 'https://openalex.org/I2279609970']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5083058332', 'display_name': 'Vincent Prévot', 'orcid': 'https://orcid.org/0000-0001-7185-3615'}, 'institutions': [{'id': 'https://openalex.org/I2279609970', 'display_name': 'Université de Lille', 'ror': 'https://ror.org/02kzqn938', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I2279609970']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}, {'id': 'https://openalex.org/I4210098046', 'display_name': 'Centre de Recherche Jean Pierre Aubert', 'ror': 'https://ror.org/00x76wb44', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I154526488', 'https://openalex.org/I4210098046']}, {'id': 'https://openalex.org/I59807433', 'display_name': 'Université Lille Nord de France', 'ror': 'https://ror.org/03btvgn05', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I59807433']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Vincent Prevot', 'raw_affiliation_strings': ['Laboratory of Development and Plasticity of the Postnatal Brain, Jean-Pierre Aubert Research Centre (JPARC), Inserm U837, University of Lille 2, Lille, 59000, France', 'NEUROBESE International Associated Laboratory, 59045 Lille cedex, France', 'Univ Lille Nord de France, School of Medicine, 59046 Lille cedex, France'], 'affiliations': [{'raw_affiliation_string': 'Univ Lille Nord de France, School of Medicine, 59046 Lille cedex, France', 'institution_ids': ['https://openalex.org/I2279609970', 'https://openalex.org/I59807433']}, {'raw_affiliation_string': 'Laboratory of Development and Plasticity of the Postnatal Brain, Jean-Pierre Aubert Research Centre (JPARC), Inserm U837, University of Lille 2, Lille, 59000, France', 'institution_ids': ['https://openalex.org/I2279609970', 'https://openalex.org/I154526488', 'https://openalex.org/I4210098046']}, {'raw_affiliation_string': 'NEUROBESE International Associated Laboratory, 59045 Lille cedex, France', 'institution_ids': []}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5052015791', 'display_name': 'Bénédicte Dehouck', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210098046', 'display_name': 'Centre de Recherche Jean Pierre Aubert', 'ror': 'https://ror.org/00x76wb44', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I154526488', 'https://openalex.org/I4210098046']}, {'id': 'https://openalex.org/I2279609970', 'display_name': 'Université de Lille', 'ror': 'https://ror.org/02kzqn938', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I2279609970']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}, {'id': 'https://openalex.org/I59807433', 'display_name': 'Université Lille Nord de France', 'ror': 'https://ror.org/03btvgn05', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I59807433']}, {'id': 'https://openalex.org/I44563897', 'display_name': "Université d'Artois", 'ror': 'https://ror.org/053x9s498', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I44563897']}], 'countries': ['FR'], 'is_corresponding': True, 'raw_author_name': 'Benedicte Dehouck', 'raw_affiliation_strings': ['Laboratory of Development and Plasticity of the Postnatal Brain, Jean-Pierre Aubert Research Centre (JPARC), Inserm U837, University of Lille 2, Lille, 59000, France', 'NEUROBESE International Associated Laboratory, 59045 Lille cedex, France', 'Univ Artois Liévin France', 'Univ Lille Nord de France, School of Medicine, 59046 Lille cedex, France'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Development and Plasticity of the Postnatal Brain, Jean-Pierre Aubert Research Centre (JPARC), Inserm U837, University of Lille 2, Lille, 59000, France', 'institution_ids': ['https://openalex.org/I4210098046', 'https://openalex.org/I2279609970', 'https://openalex.org/I154526488']}, {'raw_affiliation_string': 'NEUROBESE International Associated Laboratory, 59045 Lille cedex, France', 'institution_ids': []}, {'raw_affiliation_string': 'Univ Lille Nord de France, School of Medicine, 59046 Lille cedex, France', 'institution_ids': ['https://openalex.org/I59807433', 'https://openalex.org/I2279609970']}, {'raw_affiliation_string': 'Univ Artois Liévin France', 'institution_ids': ['https://openalex.org/I44563897']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 7, 'corresponding_author_ids': ['https://openalex.org/A5052015791'], 'corresponding_institution_ids': ['https://openalex.org/I4210098046', 'https://openalex.org/I2279609970', 'https://openalex.org/I154526488', 'https://openalex.org/I59807433', 'https://openalex.org/I44563897'], 'apc_list': None, 'apc_paid': None, 'fwci': 13.435, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 233, 'citation_normalized_percentile': {'value': 0.999813, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '521', 'issue': '15', 'first_page': '3389', 'last_page': '3405'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11872', 'display_name': 'Blood-Brain Barrier and Neurovascular Interactions', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2808', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11872', 'display_name': 'Blood-Brain Barrier and Neurovascular Interactions', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2808', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11456', 'display_name': 'Neural Mechanisms of Respiratory Control and Homeostasis', 'score': 0.9984, 'subfield': {'id': 'https://openalex.org/subfields/2807', 'display_name': 'Endocrine and Autonomic Systems'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11184', 'display_name': 'Neonatal Brain Injury and Developmental Consequences', 'score': 0.9965, 'subfield': {'id': 'https://openalex.org/subfields/2735', 'display_name': 'Pediatrics, Perinatology and Child Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/circumventricular-organs', 'display_name': 'Circumventricular organs', 'score': 0.9217491}, {'id': 'https://openalex.org/keywords/ependymal-cell', 'display_name': 'Ependymal Cell', 'score': 0.90231323}, {'id': 'https://openalex.org/keywords/subcommissural-organ', 'display_name': 'Subcommissural organ', 'score': 0.7413828}, {'id': 'https://openalex.org/keywords/blood-brain-barrier', 'display_name': 'Blood-Brain Barrier', 'score': 0.498262}, {'id': 'https://openalex.org/keywords/median-eminence', 'display_name': 'Median eminence', 'score': 0.4922332}, {'id': 'https://openalex.org/keywords/pia-mater', 'display_name': 'Pia mater', 'score': 0.4775123}, {'id': 'https://openalex.org/keywords/parenchyma', 'display_name': 'Parenchyma', 'score': 0.47372356}, {'id': 'https://openalex.org/keywords/area-postrema', 'display_name': 'Area postrema', 'score': 0.44235796}], 'concepts': [{'id': 'https://openalex.org/C2777619780', 'wikidata': 'https://www.wikidata.org/wiki/Q205925', 'display_name': 'Circumventricular organs', 'level': 3, 'score': 0.9217491}, {'id': 'https://openalex.org/C2909073510', 'wikidata': 'https://www.wikidata.org/wiki/Q1134467', 'display_name': 'Ependymal Cell', 'level': 3, 'score': 0.90231323}, {'id': 'https://openalex.org/C2777345201', 'wikidata': 'https://www.wikidata.org/wiki/Q1423193', 'display_name': 'Subcommissural organ', 'level': 2, 'score': 0.7413828}, {'id': 'https://openalex.org/C177779419', 'wikidata': 'https://www.wikidata.org/wiki/Q1053832', 'display_name': 'Tight junction', 'level': 2, 'score': 0.712869}, {'id': 'https://openalex.org/C2775857624', 'wikidata': 'https://www.wikidata.org/wiki/Q2030058', 'display_name': 'Subfornical organ', 'level': 4, 'score': 0.68514276}, {'id': 'https://openalex.org/C2778402981', 'wikidata': 'https://www.wikidata.org/wiki/Q221694', 'display_name': 'Blood–brain barrier', 'level': 3, 'score': 0.6642107}, {'id': 'https://openalex.org/C2779651940', 'wikidata': 'https://www.wikidata.org/wiki/Q54196', 'display_name': 'Cerebrospinal fluid', 'level': 2, 'score': 0.6251141}, {'id': 'https://openalex.org/C2779067335', 'wikidata': 'https://www.wikidata.org/wiki/Q1337712', 'display_name': 'Median eminence', 'level': 3, 'score': 0.4922332}, {'id': 'https://openalex.org/C2779265215', 'wikidata': 'https://www.wikidata.org/wiki/Q1647118', 'display_name': 'Pia mater', 'level': 2, 'score': 0.4775123}, {'id': 'https://openalex.org/C196822366', 'wikidata': 'https://www.wikidata.org/wiki/Q270524', 'display_name': 'Parenchyma', 'level': 2, 'score': 0.47372356}, {'id': 'https://openalex.org/C2776459250', 'wikidata': 'https://www.wikidata.org/wiki/Q640532', 'display_name': 'Area postrema', 'level': 3, 'score': 0.44235796}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.3918881}, {'id': 'https://openalex.org/C2777003273', 'wikidata': 'https://www.wikidata.org/wiki/Q164386', 'display_name': 'Hypothalamus', 'level': 2, 'score': 0.3382494}, {'id': 'https://openalex.org/C105702510', 'wikidata': 'https://www.wikidata.org/wiki/Q514', 'display_name': 'Anatomy', 'level': 1, 'score': 0.32770783}, {'id': 'https://openalex.org/C169760540', 'wikidata': 'https://www.wikidata.org/wiki/Q207011', 'display_name': 'Neuroscience', 'level': 1, 'score': 0.3203143}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.29815024}, {'id': 'https://openalex.org/C529278444', 'wikidata': 'https://www.wikidata.org/wiki/Q47273', 'display_name': 'Central nervous system', 'level': 2, 'score': 0.23591352}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.22638589}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.16135857}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.097835034}, {'id': 'https://openalex.org/C198710026', 'wikidata': 'https://www.wikidata.org/wiki/Q898218', 'display_name': 'Renin–angiotensin system', 'level': 3, 'score': 0.0}, {'id': 'https://openalex.org/C84393581', 'wikidata': 'https://www.wikidata.org/wiki/Q82642', 'display_name': 'Blood pressure', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D002555', 'descriptor_name': 'Cerebrospinal Fluid', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000906', 'descriptor_name': 'Antibodies', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D031608', 'descriptor_name': 'Area Postrema', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D001812', 'descriptor_name': 'Blood-Brain Barrier', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D001921', 'descriptor_name': 'Brain', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D002463', 'descriptor_name': 'Cell Membrane Permeability', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002552', 'descriptor_name': 'Cerebral Ventricles', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D063928', 'descriptor_name': 'Ependymoglial Cells', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D007150', 'descriptor_name': 'Immunohistochemistry', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008473', 'descriptor_name': 'Median Eminence', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008810', 'descriptor_name': 'Mice, Inbred C57BL', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010539', 'descriptor_name': 'Permeability', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013351', 'descriptor_name': 'Subcommissural Organ', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D013356', 'descriptor_name': 'Subfornical Organ', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D062725', 'descriptor_name': 'Tight Junction Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/cne.23355', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4210186231', 'display_name': 'The Journal of Comparative Neurology', 'issn_l': '0021-9967', 'issn': ['0021-9967', '1096-9861'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc3973970', 'pdf_url': 'https://europepmc.org/articles/pmc3973970?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973970', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/23649873', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc3973970', 'pdf_url': 'https://europepmc.org/articles/pmc3973970?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 70, 'referenced_works': ['https://openalex.org/W124370292', 'https://openalex.org/W1269376548', 'https://openalex.org/W1480042661', 'https://openalex.org/W1600456231', 'https://openalex.org/W1622758820', 'https://openalex.org/W1728099308', 'https://openalex.org/W1826484674', 'https://openalex.org/W1876616931', 'https://openalex.org/W1965471831', 'https://openalex.org/W1968329147', 'https://openalex.org/W1969597097', 'https://openalex.org/W1974030884', 'https://openalex.org/W1974293639', 'https://openalex.org/W1980127660', 'https://openalex.org/W1982252520', 'https://openalex.org/W1982846560', 'https://openalex.org/W1983479989', 'https://openalex.org/W1983953944', 'https://openalex.org/W1988551550', 'https://openalex.org/W1992801198', 'https://openalex.org/W1996602827', 'https://openalex.org/W1997494318', 'https://openalex.org/W2000689107', 'https://openalex.org/W2006340543', 'https://openalex.org/W2008016881', 'https://openalex.org/W2008661951', 'https://openalex.org/W2012029881', 'https://openalex.org/W2015541518', 'https://openalex.org/W2017163181', 'https://openalex.org/W2025149712', 'https://openalex.org/W2027381668', 'https://openalex.org/W2029592985', 'https://openalex.org/W2031632319', 'https://openalex.org/W2031759209', 'https://openalex.org/W2031810388', 'https://openalex.org/W2031832348', 'https://openalex.org/W2032677556', 'https://openalex.org/W2033446860', 'https://openalex.org/W2039585707', 'https://openalex.org/W2050393803', 'https://openalex.org/W2050998289', 'https://openalex.org/W2053336803', 'https://openalex.org/W2063589636', 'https://openalex.org/W2070139936', 'https://openalex.org/W2075445571', 'https://openalex.org/W2075711816', 'https://openalex.org/W2085112083', 'https://openalex.org/W2087823851', 'https://openalex.org/W2100232740', 'https://openalex.org/W2105535336', 'https://openalex.org/W2111534880', 'https://openalex.org/W2111760377', 'https://openalex.org/W2114895224', 'https://openalex.org/W2122618633', 'https://openalex.org/W2127857891', 'https://openalex.org/W2132024007', 'https://openalex.org/W2155957079', 'https://openalex.org/W2158026264', 'https://openalex.org/W2159464926', 'https://openalex.org/W2159588837', 'https://openalex.org/W2159821105', 'https://openalex.org/W2165059130', 'https://openalex.org/W2406287208', 'https://openalex.org/W2407957160', 'https://openalex.org/W2468854518', 'https://openalex.org/W2614988120', 'https://openalex.org/W2754032574', 'https://openalex.org/W2884760551', 'https://openalex.org/W3007487704', 'https://openalex.org/W4290433844'], 'related_works': ['https://openalex.org/W4235410276', 'https://openalex.org/W294952274', 'https://openalex.org/W2776408588', 'https://openalex.org/W2735859817', 'https://openalex.org/W2102583690', 'https://openalex.org/W2089187209', 'https://openalex.org/W2080277737', 'https://openalex.org/W2044901444', 'https://openalex.org/W2001763149', 'https://openalex.org/W1535856286'], 'abstract_inverted_index': {'ABSTRACT': [0], 'Tanycytes': [1], 'are': [2, 186], 'highly': [3], 'specialized': [4], 'ependymal': [5, 35, 128, 130, 173], 'cells': [6, 131, 155], 'that': [7, 48, 138, 171, 184], 'form': [8], 'a': [9, 22, 41, 177, 187], 'blood–cerebrospinal': [10], 'fluid': [11], '(CSF)': [12], 'barrier': [13, 62], 'at': [14], 'the': [15, 18, 28, 32, 52, 57, 65, 68, 72, 78, 81, 91, 98, 109, 115, 133, 141, 144, 148, 203, 206, 208, 211], 'level': [16], 'of': [17, 31, 43, 56, 61, 74, 80, 111, 118, 143, 190], 'median': [19], 'eminence': [20], '(ME),': [21], 'circumventricular': [23], 'organ': [24], '(CVO)': [25], 'located': [26], 'in': [27, 51, 201], 'tuberal': [29], 'region': [30], 'hypothalamus.': [33], 'This': [34], 'layer': [36, 174], 'harbors': [37], 'well‐organized': [38, 157], 'tight': [39, 85, 158], 'junctions,': [40], 'hallmark': [42], 'central': [44], 'nervous': [45], 'system': [46], 'barriers': [47, 113], 'is': [49], 'lacking': [50], 'fenestrated': [53, 149], 'portal': [54], 'vessels': [55], 'ME.': [58], 'The': [59], 'displacement': [60], 'properties': [63], 'from': [64], 'vascular': [66], 'to': [67, 107, 146], 'ventricular': [69, 116], 'side': [70], 'allows': [71], 'diffusion': [73, 89, 178], 'blood‐borne': [75], 'molecules': [76], 'into': [77, 90, 140, 198], 'parenchyma': [79, 142], 'ME': [82], 'while': [83], 'tanycyte': [84, 112], 'junctions': [86, 159], 'control': [87], 'their': [88, 161, 199], 'CSF,': [92], 'thus': [93], 'maintaining': [94], 'brain': [95, 120], 'homeostasis.': [96], 'In': [97], 'present': [99], 'work,': [100], 'we': [101], 'combined': [102], 'immunohistochemical': [103], 'and': [104, 193, 210], 'permeability': [105, 168], 'studies': [106, 169], 'investigate': [108], 'presence': [110], 'along': [114], 'walls': [117], 'other': [119], 'CVOs.': [121], 'Our': [122], 'data': [123], 'indicate': [124], 'that,': [125], 'unlike': [126], 'cuboidal': [127], 'cells,': [129], 'bordering': [132], 'CVOs': [134, 145, 192], 'possess': [135], 'long': [136], 'processes': [137], 'project': [139], 'reach': [147], 'capillary': [150], 'network.': [151], 'Remarkably,': [152], 'these': [153, 166, 214], 'tanycyte‐like': [154], 'display': [156], 'around': [160], 'cell': [162], 'bodies.': [163], 'Consistent': [164], 'with': [165], 'observations,': [167], 'show': [170], 'this': [172], 'acts': [175], 'as': [176], 'barrier.': [179], 'Together,': [180], 'our': [181], 'results': [182], 'suggest': [183], 'tanycytes': [185], 'characteristic': [188], 'feature': [189], 'all': [191], 'yield': [194], 'potential': [195], 'new': [196], 'insights': [197], 'involvement': [200], 'regulating': [202], 'exchange': [204], 'between': [205], 'blood,': [207], 'brain,': [209], 'CSF': [212], 'within': [213], '“brain': [215], 'windows.”': [216], 'J.': [217], 'Comp.': [218], 'Neurol.': [219], '521:3389‐3405,': [220], '2013.': [221], '©': [222], '2013': [223], 'Wiley': [224], 'Periodicals,': [225], 'Inc.': [226]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1941456052', 'counts_by_year': [{'year': 2024, 'cited_by_count': 8}, {'year': 2023, 'cited_by_count': 17}, {'year': 2022, 'cited_by_count': 18}, {'year': 2021, 'cited_by_count': 31}, {'year': 2020, 'cited_by_count': 23}, {'year': 2019, 'cited_by_count': 25}, {'year': 2018, 'cited_by_count': 19}, {'year': 2017, 'cited_by_count': 26}, {'year': 2016, 'cited_by_count': 16}, {'year': 2015, 'cited_by_count': 22}, {'year': 2014, 'cited_by_count': 21}, {'year': 2013, 'cited_by_count': 5}], 'updated_date': '2024-09-19T22:12:40.977796', 'created_date': '2016-06-24'}