2012 ACCF/AHA/HRS Focused Update Incorporated Into the ACCF/AHA/HRS 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities

Name: Work Video:
Duration: 3 min 30 s
Andrew E. Epstein; John Dimarco; Kenneth A. Ellenbogen; N.A. Mark Estes; Roger A. Freedman; Leonard S. Gettes; A. Marc Gillinov; Gabriel Gregoratos; Stephen C. Hammill; David L. Hayes; Mark A. Hlatky; L. Kristin Newby; Richard L. Page; Mark H. Schoenfeld; Michael J. Silka; Lynne W. Stevenson; Michael O. Sweeney; Cynthia M. Tracy; Andrew E. Epstein; Dawood Darbar; John Dimarco; Sandra B. Dunbar; N.A. Mark Estes; T. Bruce Ferguson; Stephen C. Hammill; Pamela Karasik; Mark S. Link; Joseph E. Marine; Mark H. Schoenfeld; Amit J. Shanker; Michael J. Silka; Lynne W. Stevenson; William G. Stevenson; Paul D. Varosy; Jeffrey L. Anderson; Alice K. Jacobs; Jonathan L. Halperin; Nancy M. Albert; Mark A. Creager; David L. DeMets; Steven M. Ettinger; Robert A. Guyton; Judith S. Hochman; Frederick G. Kushner; E. Magnus Ohman; William G. Stevenson; Clyde W. Yancy
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3827, 3845, 3849, 3856, 3876, 3882, 3915, 3953, 3968, 3987, 3993, 4034, 4044, 4049, 4086, 4104, 4157, 4175, 4183], 'Society': [76, 3031, 3339, 3343, 3425, 3429, 3660, 3664, 3724, 3728, 4101], 'Andrew': [77, 189, 361, 466], 'E.': [78, 190, 235, 247, 344, 362, 364, 467, 469, 577, 579, 609, 611, 777], 'Epstein,': [79, 191], 'MD,': [80, 87, 94, 101, 108, 114, 120, 125, 131, 137, 144, 150, 156, 163, 170, 175, 181, 186, 192, 198, 204, 218, 225, 231, 237, 243, 249, 255, 262, 268, 273, 278, 286, 292, 298, 304, 316, 325, 330, 335, 341, 347, 351, 358, 3162], 'FACC,': [81, 89, 95, 102, 109, 115, 121, 126, 132, 138, 145, 151, 157, 164, 171, 187, 193, 199, 206, 219, 226, 232, 238, 244, 250, 256, 263, 269, 274, 279, 287, 293, 299, 305, 317, 326, 331, 336, 342, 348, 352, 359, 3163], 'FAHA,': [82, 96, 103, 116, 122, 127, 139, 146, 152, 158, 165, 188, 194, 214, 220, 227, 257, 280, 294, 300, 306, 318, 337, 343], 'FHRS,': [83, 90, 97, 104, 110, 133, 140, 159, 166, 195, 200, 207, 221, 233, 239, 245, 251, 258, 264], 'John': [84, 201, 367, 496], 'P.': [85, 202, 368, 370, 497, 499], 'DiMarco,': [86, 203], 'PhD,': [88, 205, 310, 321], 'Kenneth': [91, 373], 'A.': [92, 106, 117, 142, 314, 328, 374, 376, 386, 388, 397, 420, 422, 744, 746, 760, 762], 'Ellenbogen,': [93], 'N.A.': [98, 215, 379, 528], 'Mark': [99, 141, 160, 216, 240, 252, 313, 380, 382, 419, 437, 529, 531, 592, 624, 743], 'EstesIII,': [100, 217], 'Roger': [105, 385], 'Freedman,': [107], 'Leonard': [111, 391], 'S.': [112, 241, 333, 392, 394, 593, 595, 766, 768], 'Gettes,': [113], 'Marc': [118, 398, 400], 'Gillinov,': [119], 'Gabriel': [123, 403], 'Gregoratos,': [124], 'Stephen': [128, 228, 407, 560], 'C.': [129, 229, 408, 410, 561, 563, 1978], 'Hammill,': [130, 230], 'David': [134, 319, 413, 749], 'L.': [135, 147, 154, 290, 302, 414, 416, 425, 432, 434, 720, 722, 732, 734, 3160], 'Hayes,': [136], 'Hlatky,': [143], 'Kristin': [148, 426, 428], 'Newby,': [149], 'Richard': [153, 431], 'Page,': [155], 'H.': [161, 253, 438, 440, 625, 627], 'Schoenfeld,': [162, 254], 'Michael': [167, 178, 265, 443, 455, 656], 'J.': [168, 260, 266, 444, 446, 641, 643, 657, 659], 'Silka,': [169, 267], 'Lynne': [172, 270, 449, 672], 'Warner': [173, 271, 450, 452, 673, 675], 'Stevenson,': [174, 272, 277, 350], 'FACC': [176, 182], 'O.': [179, 456, 458], 'Sweeney,': [180], 'Cynthia': [183, 460], 'M.': [184, 308, 323, 461, 463, 738, 740, 754, 756], 'Tracy,': [185], 'Dawood': [196, 482], 'Darbar,': [197], 'Sandra': [208, 512], 'B.': [209, 513, 515], 'Dunbar,': [210], 'RN,': [211], 'DSN,': [212], 'FAAN,': [213], 'T.': [222, 544], 'Bruce': [223, 545, 547], 'FergusonJr,': [224], 'Pamela': [234, 576], 'Karasik,': [236], 'Link,': [242], 'Joseph': [246, 608], 'Marine,': [248], 'Amit': [259, 640], 'Shanker,': [261], 'William': [275, 349, 688, 783], 'G.': [276, 339, 689, 691, 772, 774], 'FHRS': [281, 288], 'Paul': [283, 704], 'D.': [284, 705, 707], 'Varosy,': [285], 'Jeffrey': [289, 719], 'Anderson,': [291, 3161], 'Alice': [295, 725], 'K.': [296, 726, 728], 'Jacobs,': [297], 'Jonathan': [301, 731], 'Halperin,': [303], 'Nancy': [307, 737], 'Albert,': [309], 'CCNS,': [311], 'CCRN,': [312], 'Creager,': [315], 'DeMets,': [320], 'Steven': [322, 753], 'Ettinger,': [324], 'Robert': [327, 759], 'Guyton,': [329], 'Judith': [332, 765], 'Hochman,': [334], 'Frederick': [338, 771], 'Kushner,': [340], 'Magnus': [345, 778, 780], 'Ohman,': [346], 'FAHA': [353, 360], 'Clyde': [355, 787], 'W.': [356, 788, 790], 'Yancy,': [357], 'EpsteinAndrew': [363, 468], 'Epstein': [365, 470], ',': [366, 372, 378, 384, 390, 396, 402, 406, 412, 418, 424, 430, 436, 442, 448, 465, 481, 495, 511, 527, 543, 559, 575, 591, 607, 623, 639, 655, 671, 687, 724, 730, 736, 742, 748, 752, 758, 764, 770, 776, 782], 'DiMarcoJohn': [369, 498], 'DiMarco': [371, 500], 'EllenbogenKenneth': [375], 'Ellenbogen': [377], 'EstesIIIN.A.': [381, 530], 'EstesIII': [383, 532], 'FreedmanRoger': [387], 'Freedman': [389], 'GettesLeonard': [393], 'Gettes': [395], 'GillinovA.': [399], 'Gillinov': [401], 'GregoratosGabriel': [404], 'Gregoratos': [405], 'HammillStephen': [409, 562], 'Hammill': [411, 564], 'HayesDavid': [415], 'Hayes': [417], 'HlatkyMark': [421], 'Hlatky': [423], 'NewbyL.': [427], 'Newby': [429], 'PageRichard': [433], 'Page': [435], 'SchoenfeldMark': [439, 626], 'Schoenfeld': [441, 628], 'SilkaMichael': [445, 658], 'Silka': [447, 660], 'StevensonLynne': [451, 674], 'Stevenson': [453, 676, 692, 785], 'SweeneyMichael': [457], 'Sweeney': [459], 'TracyCynthia': [462], 'Tracy': [464], '*,': [471, 485, 501, 517, 533, 549, 565, 581, 597, 613, 629, 645, 661, 677, 693, 709], 'Appendix': [472, 486, 502, 518, 534, 550, 566, 582, 598, 614, 630, 646, 662, 678, 694, 710, 2954], '4,': [473, 487, 503, 519, 535, 551, 567, 583, 599, 615, 631, 647, 663, 679, 695, 711, 2974], '†,': [474, 488, 504, 520, 536, 552, 568, 584, 600, 616, 632, 648, 664, 680, 696, 712], '‡,': [475, 489, 505, 521, 537, 553, 569, 585, 601, 617, 633, 649, 665, 681, 697, 713], '§,': [476, 490, 506, 522, 538, 554, 570, 586, 602, 618, 634, 650, 666, 682, 698, 714], '‖,': [477, 491, 507, 523, 539, 555, 571, 587, 603, 619, 635, 651, 667, 683, 699, 715], '¶,': [478, 492, 508, 524, 540, 556, 572, 588, 604, 620, 636, 652, 668, 684, 700, 716], '#,': [479, 493, 509, 525, 541, 557, 573, 589, 605, 621, 637, 653, 669, 685, 701, 717], '**': [480, 494, 510, 526, 542, 558, 574, 590, 606, 622, 638, 654, 670, 686, 702, 718], 'DarbarDawood': [483], 'Darbar': [484], 'DunbarSandra': [514], 'Dunbar': [516], 'FergusonJrT.': [546], 'FergusonJr': [548], 'KarasikPamela': [578], 'Karasik': [580], 'LinkMark': [594], 'Link': [596], 'MarineJoseph': [610], 'Marine': [612], 'ShankerAmit': [642], 'Shanker': [644], 'StevensonWilliam': [690, 784], 'VarosyPaul': [706], 'Varosy': [708], 'AndersonJeffrey': [721], 'Anderson': [723], 'JacobsAlice': [727], 'Jacobs': [729], 'HalperinJonathan': [733], 'Halperin': [735], 'AlbertNancy': [739], 'Albert': [741], 'CreagerMark': [745], 'Creager': [747], 'DeMetsDavid': [750], 'DeMets': [751], 'EttingerSteven': [755], 'Ettinger': [757], 'GuytonRobert': [761], 'Guyton': [763], 'HochmanJudith': [767], 'Hochman': [769], 'KushnerFrederick': [773], 'Kushner': [775], 'OhmanE.': [779], 'Ohman': [781], 'YancyClyde': [789], 'Yancy': [791], 'Originally': [792], 'published19': [793], 'Dec': [794], '2012https://doi.org/10.1161/CIR.0b013e318276ce9bCirculation.': [795], '2013;127:e283–e352Other': [796], 'version(s)': [797], 'this': [799, 808, 1439, 2058, 2966, 2993, 3043, 3151, 3403, 3477, 3690, 3738, 3852, 3940, 4112, 4146], 'articleYou': [800], 'are': [801, 1322, 1443, 1507, 1556, 1645, 1683, 1768, 1939, 1945, 1962, 1965, 1974, 1984, 1995, 2005, 2030, 2387, 2394, 2452, 2561, 2591, 2618, 2623, 2740, 2800, 2868, 2888, 2938, 2951, 2968, 3046, 3302, 3384, 3854, 4041, 4199], 'viewing': [802], 'most': [804, 1381, 2492, 2495], 'recent': [805, 4032], 'version': [806, 2093, 3153], 'article.': [809], 'Previous': [810, 815], 'versions:': [811], 'January': [812], '1,': [813, 2042, 2972], '2012:': [814], 'Version': [816], '1': [817, 3648], 'Table': [818, 1942, 2041], 'ContentsPreamble': [820], '(UPDATED)': [821, 824, 1240, 1267], 'e2851.': [822], 'Introduction': [823, 3171], 'e2871.1.': [825], 'Organization': [826, 3173], 'Committee': [828, 3360, 3517], 'e2871.2.': [829], 'Document': [830, 3433], 'Review': [831, 3434], 'Approval': [833], 'e2881.3.': [834], 'Methodology': [835, 3732], 'Evidence': [837, 1898], 'e2882.': [838], 'Indications': [839, 932, 1035, 1293, 2183], 'Pacing': [841, 843, 868, 886, 910, 912, 926, 929, 942, 964, 967, 1002, 4103], 'e2902.1.': [842], 'Bradycardia': [845], 'Due': [846], 'Sinus': [848, 854, 880, 2194], 'Atrioventricular': [850, 859, 870], 'Node': [851, 855, 2187], 'Dysfunction': [852, 856], 'e2902.1.1.': [853], 'e2902.1.2.': [857], 'Acquired': [858], 'Block': [860, 866, 871], 'in': [861, 943, 1164, 1234, 1310, 1326, 1399, 1405, 1473, 1593, 1694, 1740, 1889, 1941, 2040, 2110, 2116, 2181, 2318, 2382, 2391, 2396, 2406, 2458, 2494, 2515, 2531, 2551, 2576, 2587, 2613, 2651, 2677, 2940, 2953, 2970, 3067, 3206, 3255, 3272, 3304, 3316, 3594, 3606, 3689, 3737, 3769, 3774, 3851, 3939, 4074, 4184], 'Adults': [862], 'e2912.1.3.': [863], 'Chronic': [864], 'Bifascicular': [865], 'e2932.1.4.': [867], 'Associated': [872], 'With': [873, 948, 965, 1097, 1169, 1246, 1257, 1273], 'Acute': [874], 'Myocardial': [875], 'Infarction': [876], 'e2942.1.5.': [877], 'Hypersensitive': [878], 'Carotid': [879, 2193], 'Syndrome': [881, 899, 919, 1119], 'Neurocardiogenic': [883], 'Syncope': [884, 1096, 2191], 'e2952.2.': [885], 'Specific': [888, 1062], 'Conditions': [889], 'e2962.2.1.': [890], 'Transplantation': [892, 1160], 'e2972.2.2.': [893], 'Neuromuscular': [894], 'Diseases': [895], 'e2972.2.3.': [896], 'Sleep': [897], 'Apnea': [898], 'e2972.2.4.': [900], 'Sarcoidosis': [902], 'e2972.3.': [903], 'Prevention': [904, 1042, 1053, 1067, 1104], 'Termination': [906], 'Arrhythmias': [908, 916], 'by': [909, 1376, 1601, 1685, 1845, 1986, 2345, 2462, 2509, 2522, 2870, 2900, 2908, 3023, 3442, 3447, 3456, 3484, 3579, 3600, 3633, 3639, 3702, 3715, 3841, 3957, 4201], 'e2982.3.1.': [911], 'Prevent': [914], 'Atrial': [915, 921, 961, 982], 'e2982.3.2.': [917], 'Long-QT': [918, 1118], 'e2982.3.3.': [920], 'Fibrillation': [922, 983], '(Dual-Site,': [923], 'Dual-Chamber,': [924], 'Alternative': [925], 'Sites)': [927], 'e2992.4.': [928], 'Hemodynamic': [931], 'e2992.4.1.': [933], 'Resynchronization': [935], 'Therapy(UPDATED)': [936], 'e2992.4.2.': [937], 'Obstructive': [938], 'Hypertrophic': [939, 1084, 1121, 1174], 'Cardiomyopathy': [940, 1082, 1085, 1116, 1122, 1175], 'e3032.5.': [941], 'Children,': [944, 1165], 'Adolescents,': [945, 1166], 'Patients': [947, 1168], 'Congenital': [949, 1170], 'Disease': [951, 1063, 1078, 1112, 1137, 1172], 'e3032.6.': [952], 'Selection': [953, 1207], 'Pacemaker': [955, 1010, 1015, 2179], 'Device': [956], 'e3052.6.1.': [957], 'Major': [958, 3223], 'Trials': [959], 'Comparing': [960], 'or': [962, 988, 1071, 1330, 1428, 1466, 1521, 1526, 1554, 1615, 1688, 1881, 1884, 1906, 1932, 1951, 2084, 2141, 2155, 2192, 2231, 2235, 2246, 2277, 2479, 2568, 2706, 2720, 2792, 2919, 2924, 4124], 'Dual-Chamber': [963], 'Ventricular': [966, 1001, 1059, 1073, 1089, 1100, 1126, 1139, 1148, 1152], 'e3062.6.2.': [968], 'Quality': [969, 1184], 'Life': [971, 1186], 'Functional': [973], 'StatusEnd': [974], 'Points': [975, 980, 985, 991, 995], 'e3062.6.3.': [976], 'Failure': [978, 1157, 1225, 3338, 3424, 3659, 3723], 'End': [979, 984, 990, 994], 'e3072.6.4.': [981], 'e3072.6.5.': [986], 'Stroke': [987], 'Thromboembolism': [989], 'e3072.6.6.': [992], 'Mortality': [993], 'e3072.6.7.': [996], 'Importance': [997], 'Minimizing': [999], 'Unnecessary': [1000], 'e3092.6.8.': [1003], 'Role': [1004], 'Biventricular': [1006], 'Pacemakers': [1007, 3197], 'e3092.7.': [1008], 'Optimizing': [1009], 'Technology': [1011], 'Cost': [1013], 'e3102.8.': [1014], 'Follow-Up': [1016, 1030, 1214, 1220], 'e3102.8.1.': [1017], 'Length': [1018], 'Electrocardiographic': [1020], 'Samples': [1021], 'Storage': [1023], 'e3112.8.2.': [1024], 'Frequency': [1025], 'TranstelephonicMonitoring': [1027], 'e3112.8.3.': [1028], 'Remote': [1029], 'Monitoring(NEW': [1032], 'SECTION)': [1033], 'e3123.': [1034], 'Implantable': [1037, 1048, 1162, 1203, 1212, 1218, 1229], 'Cardioverter-Defibrillator': [1038, 1049, 1204, 1213, 1219, 1230], 'e3123.1.': [1040], 'Secondary': [1041, 1052, 1066], 'Sudden': [1044, 1106], 'Death': [1046, 1108], 'e3133.1.1.': [1047], 'Arrest': [1056, 1070], 'Sustained': [1058, 1072, 1099], 'Tachycardia': [1060, 1074, 1101], 'e3133.1.2.': [1061], 'States': [1064], 'e3143.1.3.': [1075], 'Coronary': [1076, 1110], 'Artery': [1077, 1111], 'e3143.1.4.': [1079], 'Nonischemic': [1080, 1114], 'Dilated': [1081, 1115], 'e3143.1.5.': [1083], 'e3143.1.6.': [1086], 'Arrhythmogenic': [1087, 1124], 'Right': [1088, 1125], 'Dysplasia/Cardiomyopathy': [1090, 1127], 'e3153.1.7.': [1091], 'Genetic': [1092], 'Arrhythmia': [1093], 'Syndromes': [1094], 'e3153.1.8.': [1095], 'Inducible': [1098], 'e3153.2.': [1102], 'Primary': [1103, 1135], 'e3153.2.1.': [1109], 'e3153.2.2.': [1113], 'e3163.2.3.': [1117], 'e3173.2.4.': [1120], 'e3173.2.5.': [1123], 'e3183.2.6.': [1128], 'Noncompaction': [1129], 'Left': [1132], 'Ventricle': [1133], 'e3183.2.7.': [1134], 'Electrical': [1136], '(Idiopathic': [1138], 'Fibrillation,': [1140], 'Short-QT': [1141], 'Syndrome,': [1142, 1144], 'Brugada': [1143], 'Catecholaminergic': [1146], 'Polymorphic': [1147], 'Tachycardia)': [1149], 'e3183.2.8.': [1150], 'Idiopathic': [1151], 'Tachycardias': [1153], 'e3193.2.9.': [1154], 'Advanced': [1155], 'e3193.3.': [1161], 'Cardioverter-Defibrillators': [1163], 'e3213.3.1.': [1173], 'e3233.4.': [1176], 'Limitations': [1177], 'Other': [1179, 1249, 1260, 1276, 1287], 'Considerations': [1180], 'e3233.4.1.': [1181], 'Impact': [1182], '(Inappropriate': [1187], 'Shocks)': [1188], 'e3233.4.2.': [1189], 'Surgical': [1190], 'Needs': [1191], 'e3233.4.3.': [1192], 'Patient': [1193], 'Longevity': [1194], 'Comorbidities': [1196], 'e3243.4.4.': [1197], 'Terminal': [1198], 'Care': [1199], 'e3253.5.': [1200], 'Cost-Effectiveness': [1201], 'e3263.6.': [1206], 'ImplantableCardioverter-Defibrillator': [1209], 'Generators': [1210], 'e3263.7.': [1211], 'e3273.7.1.': [1215], 'Elements': [1216], 'e3283.7.2.': [1221], 'Focus': [1222], 'After': [1226], 'First': [1227], 'Appropriate': [1228], 'e3284.': [1232], 'Areas': [1233], 'Need': [1235], 'Further': [1237], 'Research': [1238], 'e329References': [1239], 'e329Appendix': [1241], '1.': [1242, 1943, 2158, 2167], 'Author': [1244, 1271], 'Relationships': [1245, 1256, 1272, 1284], 'Industry': [1247, 1258, 1274], 'Entities': [1250, 1261, 1277, 1288], '(Relevant)': [1251, 1262, 1278], 'e343Appendix': [1252], '2.': [1253, 2176], 'Reviewer': [1255, 1283], 'e345Appendix': [1263], '3.': [1264], 'Abbreviations': [1265], 'List': [1266], 'e347Appendix': [1268], '4.': [1269, 2955], '2012': [1270, 1282, 1292, 1721, 1816, 2062, 2104, 2360, 2931, 2958, 3017, 3145, 3348, 3389, 3628, 3695], '(NEW)': [1279, 1289, 1297], 'e348Appendix': [1280], '5.': [1281], 'WithIndustry': [1285], 'e350Appendix': [1290], '6.': [1291], 'CRT': [1295], 'Therapy–Algorithm': [1296], 'e352Preamble': [1298], '(UPDATED)It': [1299], 'is': [1300, 1424, 1607, 1612, 1647, 1692, 1781, 1854, 1883, 1885, 1900, 2020, 2038, 2065, 2077, 2085, 2108, 2356, 2556, 3007, 3020, 3082, 3112, 3121, 3687, 3864, 3906, 4003, 4025, 4141, 4148, 4208], 'important': [1301, 1433, 1703, 1772], 'that': [1302, 1359, 1546, 1682, 1708, 1807, 1877, 1938, 2386, 2487, 2523, 2584, 2711, 2786, 2811, 2838, 3084, 3099, 3156, 3228, 3261, 3751, 3894, 3926, 3971, 4039, 4145, 4161], 'medical': [1304, 1498, 2319, 2335, 2341, 2653, 3808], 'profession': [1305], 'play': [1306], 'a': [1307, 1512, 1523, 1616, 1672, 1711, 1727, 1761, 1788, 1878, 2007, 2400, 2446, 2464, 2503, 2526, 2670, 2715, 2806, 2827, 2845, 2897, 2909, 3122, 3400, 3550, 3567, 3898, 3903, 3909, 3950, 4056, 4063, 4189], 'significant': [1308, 3470, 3507, 3524, 3541, 3568], 'role': [1309], 'critically': [1311], 'evaluating': [1312], 'use': [1314, 3867, 3896, 3921], 'diagnostic': [1316], 'procedures': [1317, 1352], 'therapies': [1319, 1354, 1555], 'as': [1320, 1457, 1558, 1560, 1770, 1871, 1873, 1928, 1947, 1953, 1976, 2343, 2563, 2714, 2768, 2770, 2790, 2815, 2890, 2996, 3091, 3387, 3645, 3647, 3908, 4037], 'they': [1321, 2622, 3565], 'introduced': [1323], 'tested': [1325], 'detection,': [1328], 'management,': [1329, 2473, 3879], 'prevention': [1331, 2475], 'disease': [1333, 1410], 'states.': [1334], 'Rigorous': [1335], 'expert': [1337, 1968], 'analysis': [1338], 'available': [1341, 2251, 2255, 2259, 2268, 2289, 2293, 2299, 2390, 2995, 3009], 'data': [1342, 1487, 1536, 1579, 1637, 1687, 1746, 1829, 1961, 2004, 2590], 'documenting': [1343], 'absolute': [1344], 'relative': [1346], 'benefits': [1347], 'risks': [1349, 1868], 'those': [1351, 2749, 3381], 'can': [1355, 4018, 4051], 'produce': [1356], 'helpful': [1357], 'guidelines': [1358, 1404, 1431, 1596, 2374, 2451, 2482, 2536, 2560, 3088, 3863, 3980], 'improve': [1360], 'effectiveness': [1362, 2124, 2137], 'care,': [1364, 3318, 3826], 'optimize': [1365], 'patient': [1366, 1544, 1715, 1753, 1776, 2376, 2426, 2505, 2514, 2595, 2628, 3948, 3958], 'outcomes,': [1367, 2635], 'favorably': [1369], 'affect': [1370, 1809, 2634], 'overall': [1372], 'cost': [1373, 1572], 'care': [1375, 1754, 2501, 2555, 2596], 'focusing': [1377], 'resources': [1378], 'effective': [1382, 2619], 'strategies.The': [1383], 'Foundation': [1388], '(ACCF)': [1389], '(AHA)': [1395], 'have': [1396, 1478, 1710, 1749, 2145, 2854, 3157, 3225, 3229, 3251, 3292], 'jointly': [1397], 'engaged': [1398], 'production': [1401], 'such': [1403, 2784, 4143], 'area': [1407, 2553], 'cardiovascular': [1409, 1434, 2325, 3317, 3321], 'since': [1411], '1980.': [1412], 'The': [1413, 1491, 1778, 1849, 1895, 1912, 2032, 2481, 2497, 2580, 2930, 3013, 3294, 3326, 3394, 3410, 3573, 3591, 3609, 3694, 3892], 'ACCF/AHA': [1414, 1628, 2346, 2372, 2436, 2449, 2862, 3086, 3165], '(Task': [1420], 'Force),': [1421], 'whose': [1422], 'charge': [1423], 'develop,': [1426, 1464], 'update,': [1427, 1465, 3350], 'revise': [1429, 1467, 1677], 'practice': [1430, 1656, 2011, 2373, 2423, 2450, 3087, 3935], 'diseases': [1435, 2478], 'procedures,': [1437], 'directs': [1438], 'effort.': [1440], 'Writing': [1441, 1505, 2797, 3036, 3359, 3392, 3556], 'committees': [1442, 1506], 'charged': [1444, 1509], 'with': [1445, 1632, 1864, 1922, 2087, 2615, 2809, 2832, 3094, 3115, 3246, 3473, 3510, 3527, 3544, 3571, 3603, 3932, 3949], 'task': [1447], 'performing': [1449], 'an': [1450, 1458, 1648, 1659, 1695, 1750, 1855, 1901, 2997, 3946, 4015], 'assessment': [1451], 'evidence': [1454, 1519, 1640, 1691, 1806, 1824, 1874, 1918, 1926, 3743, 3767, 4079, 4177], 'acting': [1456], 'independent': [1459], 'group': [1460, 1840, 1914, 2019, 2416, 2732, 2842, 2852, 2886, 2903, 2945, 2984, 3019, 3037, 3412, 3685], 'authors': [1462], 'written': [1468], 'recommendations': [1469, 1592, 1644, 1681, 1832, 1964, 1980, 2050, 2071, 2133, 2617, 2895, 2925, 3140, 3548, 3575, 3735, 3938], 'clinical': [1471, 1583, 1655, 1732, 1971, 1988, 1993, 2459, 3934, 4029], 'practice.Experts': [1472], 'subject': [1475, 3837], 'under': [1476, 3113], 'consideration': [1477, 1865], 'been': [1479, 2146, 3158, 3226, 3252, 3480, 4129], 'selected': [1480, 3351, 3848], 'from': [1481, 1496, 1569, 1792, 2534, 2936, 3143, 3286, 3416, 3651, 4014, 4097], 'both': [1482, 3050, 3263], 'organizations': [1483], 'examine': [1485], 'subject-specific': [1486], 'write': [1489], 'guidelines.': [1490, 1657], 'process': [1492, 1675], 'includes': [1493, 2860, 4172, 4188], 'additional': [1494, 2589, 3458, 3601], 'representatives': [1495, 3329, 3415], 'other': [1497, 1743, 2232, 2247, 2638, 2835, 3766, 3923, 3969], 'practitioner': [1499], 'specialty': [1501], 'groups': [1502], 'when': [1503, 2608, 4118], 'appropriate.': [1504, 1954, 2539], 'specifically': [1508], 'perform': [1511], 'literature': [1513, 1790, 3747], 'review,': [1514], 'weigh': [1515], 'strength': [1517], 'against': [1522], 'particular': [1524, 1552, 2504, 2671, 3904], 'treatment': [1525, 1706, 1862, 1880, 1910, 2140, 2430, 2612, 2672, 3888, 3901, 3944], 'procedure,': [1527], 'include': [1529, 1803, 3495, 3981], 'estimates': [1530], 'expected': [1532], 'health': [1533], 'outcomes': [1534, 1584, 1716], 'where': [1535, 2554], 'exist.': [1537], 'Patient-specific': [1538], 'modifiers,': [1539], 'comorbidities,': [1540, 3959], 'issues': [1542, 2000], 'preference': [1545], 'may': [1547, 1808, 1892, 2529, 2537, 2632, 2694, 2712, 2787, 2812, 2916, 3242, 3927, 3954, 3977], 'influence': [1548], 'choice': [1550], 'tests': [1553], 'considered,': [1557], 'well': [1559, 1872, 2769, 3646], 'frequency': [1561], 'follow-up': [1563, 3311, 3994, 4002], 'cost-effectiveness.': [1565], 'When': [1566, 1979, 2558], 'available,': [1567, 1963, 2006], 'information': [1568, 3002, 3674, 4110], 'studies': [1570, 1766, 2404, 3224], 'will': [1573, 1585, 1597, 2364, 2601], 'be': [1574, 1598, 1785, 2080, 2365, 2507, 2538, 2574, 2602, 2661, 2675, 2695, 2788, 2813, 2906, 3243, 3399, 3928, 3955, 4009, 4019, 4167], 'considered;': [1575], 'however,': [1576, 4138], 'review': [1577, 1729, 1791, 1825, 3104], 'efficacy': [1581], 'constitute': [1586], 'primary': [1588, 3974], 'basis': [1589, 2022, 2565, 3367], 'preparing': [1591], 'these': [1594, 2535, 2559, 2599, 2616, 3106], 'guidelines.The': [1595], 'reviewed': [1599, 1693, 2869, 3441, 3481, 3599, 3632, 3832], 'annually': [1600], 'Force.': [1604], 'Each': [1605], 'guideline': [1606, 1643, 1680, 1798, 2347, 2607, 2739, 2818, 2894, 2967, 3547, 3574], 'considered': [1608, 4054], 'current': [1609, 1812, 2010, 2112, 2745, 3110, 3119, 3378, 4066], 'unless': [1610], 'it': [1611, 1620, 4171, 4187], 'updated,': [1613], 'revised,': [1614], 'published': [1617, 1745, 3205, 3688, 3773, 3840, 3850], 'addendum': [1618], 'declares': [1619], 'out': [1621], 'date': [1623, 1794], 'no': [1625, 2028, 2855, 3469, 3540], 'longer': [1626], 'official': [1627, 3047, 3444, 3635], 'policy.': [1629], 'Keeping': [1630], 'pace': [1631], 'stream': [1634], 'new': [1636, 1665, 1744, 1805, 2055, 2353, 2828], 'evolving': [1639, 1686], 'which': [1642, 1959, 2002, 2043, 2532, 2588, 2690, 3241, 3494], 'based': [1646, 1786, 1966], 'ongoing': [1649, 1696], 'challenge': [1650], 'timely': [1652], 'development': [1653, 2101], 'In': [1658, 2114, 2657, 3475], 'effort': [1660, 2644, 2701], 'respond': [1662, 1701], 'promptly': [1663], 'evidence,': [1666], 'has': [1670, 2330, 3407, 3479, 4127], 'created': [1671], '"focused': [1673], 'update"': [1674], 'existing': [1679, 2750], 'affected': [1684], 'opinion.': [1689], 'New': [1690], 'fashion': [1697], 'more': [1699, 2597], 'efficiently': [1700], 'science': [1704], 'trends': [1707], 'could': [1709], 'major': [1712, 3270], 'impact': [1713, 1751, 2420], 'quality': [1718, 2546, 2577], 'care.The': [1720], 'focused': [1722, 1779, 1817, 1837, 2063, 2361, 3349, 3404, 3629, 3696], 'update': [1723, 1780, 1818, 1838, 2064, 2362, 3405, 3630, 3697], 'was': [1724, 2098, 3216, 3297, 3396, 3440, 3598, 3631, 3678, 3698, 3713, 3749], 'prompted': [1725], 'following': [1726], 'thorough': [1728, 3103], 'late-breaking': [1731], 'trials': [1733], 'presented': [1734, 2521], 'at': [1735, 1981, 2205, 3011], 'national': [1736], 'international': [1738], 'meetings,': [1739], 'addition': [1741, 2056], 'deemed': [1747, 3217], '(Section': [1755], '1.3,': [1756], '"Methodology': [1757], 'Evidence").': [1759], 'Through': [1760], 'broad-based': [1762], 'vetting': [1763], 'process,': [1764], 'included': [1767, 1940, 2109, 3328, 3414, 3779], 'identified': [1769, 1946, 2603], 'being': [1771, 3092], 'relevant': [1775, 2816, 2856, 3471, 3508, 3525, 3542, 3569], 'population.': [1777], 'not': [1782, 1886, 2204, 2227, 2242, 2388, 2917, 2990, 3782, 3857, 3886, 3918, 4042, 4070, 4128], 'intended': [1783, 2453], 'complete': [1789, 1821, 2981], 'previous': [1797, 2807, 3203], 'publication': [1799, 3701], 'but': [1800, 3780, 4068], 'rather': [1801], 'pivotal': [1804], 'changes': [1810, 2891, 3254], 'recommendations.': [1813], 'See': [1814], 'preamble': [1822], 'period.1In': [1826], 'analyzing': [1827], 'developing': [1831], 'supporting': [1834, 1919, 4176], 'text,': [1835], 'writing': [1839, 1913, 2018, 2049, 2132, 2415, 2728, 2731, 2757, 2766, 2841, 2851, 2885, 2902, 2944, 2983, 3018, 3295, 3411, 3553, 3584, 3684], 'uses': [1841], 'evidence-based': [1842], 'methodologies': [1843], 'developed': [1844], 'Force.1a': [1848], 'Class': [1850, 2069, 2349, 3910], 'Recommendation': [1852], '(COR)': [1853], 'estimate': [1856, 1902], 'size': [1859], 'effect,': [1863], 'given': [1866, 1879], 'versus': [1869, 2143], 'benefits,': [1870, 2666], 'and/or': [1875, 2881], 'agreement': [1876], 'procedure': [1882], 'useful/effective': [1887], 'some': [1890], 'situations': [1891, 2528, 2585, 3970], 'cause': [1893], 'harm.': [1894], 'Level': [1896, 2164, 2173], '(LOE)': [1899], 'certainty': [1905], 'precision': [1907], 'effect.': [1911], 'reviews': [1915, 2417], 'ranks': [1917], 'each': [1920, 2052, 2414, 2605, 2878, 3448, 3637, 3650], 'recommendation,': [1921], 'weight': [1924], 'ranked': [1927, 1975], 'LOE': [1929, 1977, 1982, 2024, 2037, 2153], 'A,': [1930], 'B,': [1931], 'C,': [1933], 'according': [1934], 'specific': [1936, 2401, 2447, 2477, 2948, 3951, 4082], 'definitions': [1937], 'Studies': [1944], 'observational,': [1948], 'retrospective,': [1949], 'prospective,': [1950], 'randomized,': [1952], 'For': [1955, 1999, 2403, 3148], 'certain': [1956], 'conditions': [1957], 'inadequate': [1960], 'consensus': [1969, 2910], 'experience': [1972], 'C': [1983, 2025], 'supported': [1985, 3021], 'historical': [1987], 'data,': [1989], 'appropriate': [1990, 3866, 4136], 'references': [1991, 2029], '(including': [1992], 'reviews)': [1994], 'cited': [1996, 3090], 'if': [1997, 2252, 2256, 2260, 2269, 2290, 2294, 2300, 2621, 3564, 4022], 'available.': [1998], 'sparse': [2003], 'survey': [2008, 3748], 'among': [2012, 2723], 'clinicians': [2014, 3314], 'members': [2015, 2725, 2733, 2763, 2799, 2876, 2932, 3038, 3352, 3501, 3518, 3535, 3558, 3581], 'recommendations,': [2026], 'cited.': [2031], 'schema': [2033], 'COR': [2035, 2149, 2685], 'summarized': [2039], 'also': [2044, 2801, 3008, 3413], 'provides': [2045, 4109], 'suggested': [2046, 2129], 'phrases': [2047, 2130], 'within': [2051, 2604], 'COR.': [2053, 2402], 'A': [2054, 2154, 3102, 4091], 'methodology': [2059, 3111], 'separation': [2066], 'III': [2070], 'delineate': [2073], 'whether': [2074, 2441], 'recommendation': [2076], 'determined': [2078], '"no': [2082], 'benefit"': [2083], 'associated': [2086], '"harm"': [2088], 'patient.': [2091, 2524], '(This': [2092], 'COR/LOE': [2096], 'table': [2097], 'used': [2099, 2366, 2562, 4209], 'document.1)': [2113], 'addition,': [2115, 2658, 3476], 'view': [2117, 2314], 'increasing': [2120], 'number': [2121, 2309], 'comparative': [2123, 2136], 'studies,': [2125, 3763], 'comparator': [2126], 'verbs': [2127], 'one': [2139], 'strategy': [2142], 'another': [2144], 'added': [2147], 'I': [2150, 3911], 'IIa,': [2152], 'B': [2156], 'only.Table': [2157], 'Applying': [2159, 2168], 'Classification': [2160, 2169], 'Recommendations': [2162, 2171], 'EvidenceTable': [2166, 2175], 'Choice': [2177], 'Generator': [2180], 'Selected': [2182], 'PacingPacemaker': [2185], 'GeneratorSinus': [2186], 'DysfunctionAtrioventricular': [2188], 'BlockNeurally': [2189], 'Mediated': [2190], 'HypersensitivitySingle-chamber': [2195], 'atrial': [2196, 2229, 2233, 2244, 2248, 3787], 'pacemakerNo': [2197], 'suspected': [2198], 'abnormality': [2199, 2273], 'atrioventricular': [2201, 2210, 2215, 2223, 2238, 2275, 2282], 'conduction': [2202, 2276], 'increased': [2206, 2278], 'risk': [2207, 2279], 'future': [2209, 2281, 2369], 'blockNot': [2211], 'appropriateNot': [2212], 'appropriateMaintenance': [2213], 'synchrony': [2216, 2224, 2239, 2263, 2284], 'during': [2217, 2225, 2240, 2264, 2285, 2877], 'pacing': [2218, 2226, 2241, 2265, 2286, 2296, 3870, 4123], 'desiredSingle-chamber': [2219], 'ventricular': [2220, 2303], 'pacemakerMaintenance': [2221], 'necessaryChronic': [2228, 2243], 'fibrillation': [2230, 2245], 'tachyarrhythmia': [2234], 'maintenance': [2236], 'tachyarrhythmiaRate': [2249], 'response': [2250, 2254, 2258, 2267, 2288, 2292, 2298], 'desiredRate': [2253, 2257, 2266, 2287, 2291, 2297], 'desiredDual-chamber': [2261], 'pacemakerAtrioventricular': [2262], 'desiredSinus': [2270], 'mechanism': [2271], 'presentSuspected': [2272], 'blockAtrioventricular': [2283], 'desiredAtrial': [2295], 'desiredSingle-lead,': [2301], 'atrial-sensing': [2302], 'pacemakerNot': [2304], 'appropriateDesire': [2305], 'limit': [2307], 'pacemaker': [2311], 'leadsNot': [2312], 'appropriateIn': [2313], 'advances': [2317, 3271], 'therapy': [2320, 2336, 2342, 3309, 4126], 'across': [2321], 'spectrum': [2323], 'diseases,': [2326, 3967], 'designated': [2331], 'term': [2333, 4203, 4207], 'guideline-directed': [2334], '(GDMT)': [2337], 'represent': [2339], 'optimal': [2340, 4012], 'defined': [2344], '(primarily': [2348], 'I)–recommended': [2350], 'therapies.': [2351, 4194], 'This': [2352, 4206], 'term,': [2354], 'GDMT,': [2355], 'incorporated': [2357, 3623], 'into': [2358, 3624], 'throughout': [2367], 'all': [2368, 2518, 2744, 2762, 2783, 2875, 3580, 3612, 3933], 'guidelines.Because': [2370], 'address': [2375], 'populations': [2377, 2427], '(and': [2378], 'healthcare': [2379, 2456, 2511, 2639], 'providers)': [2380], 'residing': [2381], 'North': [2383, 2392, 2412, 4099], 'America,': [2384, 2413, 3341, 3427, 3662, 3726], 'drugs': [2385], 'currently': [2389], 'America': [2393], 'discussed': [2395], 'text': [2398, 2923, 3142, 4160], 'without': [2399, 3033], 'performed': [2405], 'large': [2407], 'numbers': [2408], 'subjects': [2410, 3771], 'outside': [2411], 'potential': [2419, 2793], 'different': [2422], 'patterns': [2424], 'effect': [2431], 'relevance': [2433], 'target': [2437], 'population': [2438], 'determine': [2440], 'findings': [2443], 'should': [2444, 2543, 2573, 2641, 2660, 2674, 4166], 'inform': [2445, 2594], 'recommendation.The': [2448], 'assist': [2455], 'providers': [2457, 2640], 'decision': [2460, 2541, 2679], 'making': [2461, 2542, 2680], 'describing': [2463], 'range': [2465], 'generally': [2467], 'acceptable': [2468, 4193], 'approaches': [2469], 'diagnosis,': [2472], 'conditions.': [2480], 'attempt': [2483], 'define': [2485], 'practices': [2486], 'meet': [2488], 'needs': [2490], 'patients': [2493, 2659], 'circumstances.': [2496], 'ultimate': [2498], 'judgment': [2499], 'about': [2500], 'must': [2506, 2905], 'made': [2508], 'provider': [2512], 'light': [2516], 'circumstances': [2520], 'As': [2525, 3931], 'result,': [2527], 'arise': [2530, 2586, 2713], 'deviations': [2533], 'Clinical': [2540, 3075], 'consider': [2544], 'availability': [2548], 'expertise': [2550, 3605], 'provided.': [2557], 'regulatory': [2567], 'payer': [2569], 'decisions,': [2570], 'goal': [2572], 'improvement': [2575], 'care.': [2579], 'recognizes': [2583], 'needed': [2592], 'effectively;': [2598], 'areas': [2600, 3306, 3369], 'respective': [2606], 'appropriate.Prescribed': [2609], 'courses': [2610], 'accordance': [2614], 'only': [2620, 3972, 4021], 'followed.': [2624], 'Because': [2625], 'lack': [2626], 'understanding': [2629], 'adherence': [2631], 'adversely': [2633], 'physicians': [2636, 3300], 'make': [2642], 'every': [2643, 2700], 'engage': [2646], "patient's": [2648], 'active': [2649], 'participation': [2650], 'prescribed': [2652], 'regimens': [2654], 'lifestyles.': [2656], 'informed': [2662], 'risks,': [2665], 'alternatives': [2668], 'involved': [2676], 'shared': [2678], 'whenever': [2681, 3741], 'feasible,': [2682], 'particularly': [2683], 'IIa': [2686], 'IIb,': [2688], 'benefit-to-risk': [2692], 'ratio': [2693], 'lower.The': [2696], 'makes': [2699], 'avoid': [2703], 'actual,': [2704], 'potential,': [2705], 'perceived': [2707, 2789, 2814], 'conflicts': [2708, 2794], 'interest': [2710], 'result': [2716], 'industry': [2718, 2810, 2833], 'relationships': [2719, 2785, 2831, 3472, 3509, 3526, 3543], 'personal': [2721], 'interests': [2722], 'group.': [2729], 'All': [2730, 2893, 3546, 3673], 'peer': [2735, 2771, 2961, 3459, 3465], 'reviewers': [2736, 2772, 3445, 3602, 3614, 3636], 'required': [2741, 3560], 'disclose': [2743], 'healthcare–related': [2746], 'relationships,': [2747], 'including': [2748, 4055], '12': [2751], 'months': [2752], 'before': [2753], 'initiation': [2754], 'effort.For': [2758], 'guidelines,': [2761, 3936], 'committee,': [2767], 'document,': [2775], 'were': [2776, 3089, 3100, 3361, 3559, 3576, 3587, 3622, 3760, 3781], 'asked': [2777], 'provide': [2779], 'disclosure': [2780, 2987, 3001], 'statements': [2781, 2867], 'real': [2791], 'interest.': [2796], 'committee': [2798, 3296, 3327, 3374, 3554, 3557, 3585, 3610, 3831, 4053], 'strongly': [2802], 'encouraged': [2803], 'declare': [2805], 'relationship': [2808, 3570], 'development.In': [2819], 'December': [2820], '2009,': [2821], 'ACCF': [2823, 3052], 'AHA': [2825, 3513], 'implemented': [2826], 'policy': [2829, 3048, 4092], 'entities': [2836], '(RWI)': [2837], 'requires': [2839], 'chair': [2843], 'plus': [2844], 'minimum': [2846], '50%': [2848], 'RWI': [2857, 2963, 2989, 3379, 3677], '(Appendix': [2858, 3692], '4': [2859], 'definition': [2863], 'relevance).': [2865], 'These': [2866], 'conference': [2879], 'call': [2880], 'meeting': [2882], 'updated': [2889, 3139], 'occur.': [2892], 'require': [2896], 'confidential': [2898], 'vote': [2899, 2920], 'approved': [2907, 3483, 3578, 3699], 'voting': [2913, 2937], 'members.': [2914], 'Members': [2915], 'draft': [2918], 'any': [2922, 3506, 3523], 'pertaining': [2926], 'their': [2928, 3040, 3616, 3620], 'RWI.': [2929], 'who': [2933, 3301, 3382, 3586], 'recused': [2934], 'themselves': [2935, 3563], 'indicated': [2939], 'list': [2942], 'members,': [2946], 'section': [2949, 3592, 4000, 4057], 'recusals': [2950], 'noted': [2952], "authors'": [2959], "reviewers'": [2962, 3676], 'pertinent': [2964, 2991], 'disclosed': [2969], 'Appendixes': [2971], '2,': [2973], '5,': [2976], 'respectively.': [2977], 'Additionally,': [2978, 3829], 'ensure': [2980], 'transparency,': [2982], "members'": [2985], 'comprehensive': [2986], 'information—including': [2988], 'document—is': [2994], 'online': [2998, 3010], 'supplement.': [2999], 'Comprehensive': [3000], 'http://cardiosource.org/ACC/About-ACC/Who-We-Are/Leadership/Guidelines-and-Documents-Task-Forces.aspx.': [3012], 'work': [3014], 'exclusively': [3022], 'ACCF,': [3025, 3641, 3708], 'AHA,': [3026, 3452, 3491, 3642, 3709, 3844], '(HRS)': [3032], 'commercial': [3034], 'support.': [3035], 'volunteered': [3039], 'time': [3041], 'activity.': [3044], 'AHA.In': [3054], 'April': [3055], '2011,': [3056], 'Institute': [3058], 'Medicine': [3060], 'released': [3061], '2': [3062, 3443, 3634], 'reports:': [3063], 'Finding': [3064], 'What': [3065], 'Works': [3066], 'Health': [3068], 'Care:': [3069], 'Standards': [3070], 'Systematic': [3072], 'Reviews': [3073], 'We': [3078], 'Can': [3079], 'Trust.1b,1c': [3080], 'It': [3081], 'noteworthy': [3083], 'compliant': [3093], 'many': [3095, 4179], 'standards': [3098], 'proposed.': [3101], 'reports': [3107], 'our': [3109, 3231], 'way,': [3114], 'further': [3116], 'enhancements': [3117], 'anticipated.The': [3118], 'document': [3120, 3439, 3478, 3691, 3739, 3853, 3941], 'republication': [3123], '"ACCF/AHA/HRS': [3126], 'DeviceBased': [3130], 'Abnormalities"1d,': [3135], 'revised': [3136], 'incorporate': [3138], 'Update.1': [3147], 'easy': [3149], 'reference,': [3150], 'online-only': [3152], 'denotes': [3154], 'sections': [3155, 3982], 'updated.Jeffrey': [3159], 'FAHAChair,': [3164], 'Guidelines1.': [3170], '(UPDATED)1.1.': [3172], 'CommitteeThis': [3175], 'revision': [3177], '(formally': [3189], 'named': [3190], 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