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296, 375], 'hydrophobic': [67, 300], 'positions.': [68, 301], 'other': [70, 303], 'position,': [71, 304], 'depending': [72, 305], 'register': [75, 308], 'repeat,': [79, 312], 'either': [83, 316], 'acidic': [84, 317], 'or': [85, 318], 'basic': [86, 319], 'residues.': [87, 320], 'Using': [88, 321], 'NMR': [89, 147, 322, 380], 'spectroscopy,': [90, 323], 'we': [91, 324], 'show': [92, 325], 'exists': [97, 330], 'conformations': [100, 118, 182, 333, 351, 415], 'almost': [102, 335], 'equal': [103, 336], 'population': [104, 337], 'exchange': [106, 172, 339, 405], 'with': [107, 340], 'rate': [109, 342], '17': [111, 344], 's−1.': [112, 345], 'We': [113, 346], 'propose': [114, 347], 'correspond': [119, 352], 'to': [120, 193, 353, 426], 'possible': [123, 176, 356, 409], 'registers': [124, 357], 'repeat.': [128, 361], 'This': [129, 362], 'hypothesis': [130, 363], 'supported': [132, 365], 'cysteine': [135, 368], 'mutant': [136, 151, 369, 384], 'locks': [138, 371], 'protein': [140, 373], 'conformations.': [146, 379], 'spectra': [148, 381], 'showed': [152, 385], 'predicted': [154, 387], '2-fold': [155, 388], 'reduction': [156, 389], 'peaks': [158, 170, 391, 403], '15N': [161, 394], 'HSQC': [162, 395], 'spectrum': [163, 396], 'complete': [166, 399], 'removal': [167, 400], 'cross': [169, 402], 'spectra.': [173, 406], 'It': [174, 407], 'interconversion': [178, 411], 'these': [180, 413], 'may': [183, 416], 'be': [184, 417], 'triggered': [185, 418], 'external': [187, 420], 'signals': [188, 421], 'manner': [191, 424], 'similar': [192, 425], 'proposed': [195, 428], 'recently': [196, 429], 'microtubule': [199, 432], 'binding': [200, 433], 'domain': [201, 434], 'dynein': [203, 436], 'HAMP': [206, 439], 'domain.': [207, 440], 'As': [208, 441], 'result,': [210, 443], 'first': [219, 452], 'example': [220, 453], 'where': [221, 454], 'frameshift': [223, 456], 'coiled-coil': [225, 458], 'repeats': [227, 460], 'has': [228, 461], 'been': [229, 462], 'directly': [230, 463], 'observed': [231, 464], 'experimentally.': [232, 465]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2022751822', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 10}, {'year': 2018, 'cited_by_count': 3}, {'year': 2017, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 2}, {'year': 2013, 'cited_by_count': 4}, {'year': 2012, 'cited_by_count': 4}], 'updated_date': '2024-12-08T03:13:06.992119', 'created_date': '2016-06-24'}