Publication Information

{'id': 'https://openalex.org/W2021227276', 'doi': 'https://doi.org/10.1002/1531-8249(199901)45:1<48::aid-art9>3.0.co;2-v', 'title': "Modulation byDLST of the genetic risk of Alzheimer's disease in a very elderly population", 'display_name': "Modulation byDLST of the genetic risk of Alzheimer's disease in a very elderly population", 'publication_year': 1999, 'publication_date': '1999-01-01', 'ids': {'openalex': 'https://openalex.org/W2021227276', 'doi': 'https://doi.org/10.1002/1531-8249(199901)45:1<48::aid-art9>3.0.co;2-v', 'mag': '2021227276', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/9894876'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/1531-8249(199901)45:1<48::aid-art9>3.0.co;2-v', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S114530997', 'display_name': 'Annals of Neurology', 'issn_l': '0364-5134', 'issn': ['0364-5134', '1531-8249'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5111716029', 'display_name': 'Kwan‐Fu Rex Sheu', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I205783295', 'display_name': 'Cornell University', 'ror': 'https://ror.org/05bnh6r87', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I205783295']}, {'id': 'https://openalex.org/I4210117944', 'display_name': 'Burke Medical Research Institute', 'ror': 'https://ror.org/02sp1z620', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I4210117944']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Kwan-Fu Rex Sheu', 'raw_affiliation_strings': ['Burke Medical Research Institute, White Plains, NY', 'Cornell University Medical College, Manhasset, NY'], 'affiliations': [{'raw_affiliation_string': 'Cornell University Medical College, Manhasset, NY', 'institution_ids': ['https://openalex.org/I205783295']}, {'raw_affiliation_string': 'Burke Medical Research Institute, White Plains, NY', 'institution_ids': ['https://openalex.org/I4210117944']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5107928627', 'display_name': 'Abraham M. Brown', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I205783295', 'display_name': 'Cornell University', 'ror': 'https://ror.org/05bnh6r87', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I205783295']}, {'id': 'https://openalex.org/I4210117944', 'display_name': 'Burke Medical Research Institute', 'ror': 'https://ror.org/02sp1z620', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I4210117944']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Abraham M. Brown', 'raw_affiliation_strings': ['Burke Medical Research Institute, White Plains, NY', 'Cornell University Medical College, Manhasset, NY'], 'affiliations': [{'raw_affiliation_string': 'Cornell University Medical College, Manhasset, NY', 'institution_ids': ['https://openalex.org/I205783295']}, {'raw_affiliation_string': 'Burke Medical Research Institute, White Plains, NY', 'institution_ids': ['https://openalex.org/I4210117944']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5054795331', 'display_name': 'Vahram Haroutunian', 'orcid': 'https://orcid.org/0000-0001-5860-2512'}, 'institutions': [{'id': 'https://openalex.org/I98704320', 'display_name': 'Icahn School of Medicine at Mount Sinai', 'ror': 'https://ror.org/04a9tmd77', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I1320796813', 'https://openalex.org/I98704320']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Vahram Haroutunian', 'raw_affiliation_strings': ['Bronx VA Medical Center and Mount Sinai School of Medicine, Manhasset, NY'], 'affiliations': [{'raw_affiliation_string': 'Bronx VA Medical Center and Mount Sinai School of Medicine, Manhasset, NY', 'institution_ids': ['https://openalex.org/I98704320']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5043090582', 'display_name': 'Bruce S. Kristal', 'orcid': 'https://orcid.org/0000-0001-6103-7745'}, 'institutions': [{'id': 'https://openalex.org/I205783295', 'display_name': 'Cornell University', 'ror': 'https://ror.org/05bnh6r87', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I205783295']}, {'id': 'https://openalex.org/I4210117944', 'display_name': 'Burke Medical Research Institute', 'ror': 'https://ror.org/02sp1z620', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I4210117944']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Bruce S. Kristal', 'raw_affiliation_strings': ['Burke Medical Research Institute, White Plains, NY', 'Cornell University Medical College, Manhasset, NY'], 'affiliations': [{'raw_affiliation_string': 'Cornell University Medical College, Manhasset, NY', 'institution_ids': ['https://openalex.org/I205783295']}, {'raw_affiliation_string': 'Burke Medical Research Institute, White Plains, NY', 'institution_ids': ['https://openalex.org/I4210117944']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5110311181', 'display_name': 'Howard T. Thaler', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I39965400', 'display_name': 'Kettering University', 'ror': 'https://ror.org/03rcspa57', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I39965400']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Howard Thaler', 'raw_affiliation_strings': ['Sloan-Kettering Medical Research Center, Manhasset, NY'], 'affiliations': [{'raw_affiliation_string': 'Sloan-Kettering Medical Research Center, Manhasset, NY', 'institution_ids': ['https://openalex.org/I39965400']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5012284725', 'display_name': 'Martin Lesser', 'orcid': 'https://orcid.org/0000-0002-0318-5739'}, 'institutions': [{'id': 'https://openalex.org/I57206974', 'display_name': 'New York University', 'ror': 'https://ror.org/0190ak572', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I57206974']}, {'id': 'https://openalex.org/I2800496781', 'display_name': 'North Shore University Hospital', 'ror': 'https://ror.org/05m8d2x46', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1302444339', 'https://openalex.org/I2800496781']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Martin Lesser', 'raw_affiliation_strings': ['North Shore University Hospital, New York University School of Medicine, Manhasset, NY'], 'affiliations': [{'raw_affiliation_string': 'North Shore University Hospital, New York University School of Medicine, Manhasset, NY', 'institution_ids': ['https://openalex.org/I57206974', 'https://openalex.org/I2800496781']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5105274627', 'display_name': 'Rajesh N. Kalaria', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I58956616', 'display_name': 'Case Western Reserve University', 'ror': 'https://ror.org/051fd9666', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I58956616']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Rajesh N. Kalaria', 'raw_affiliation_strings': ['Case Western Reserve University Medical School, Cleveland, OH'], 'affiliations': [{'raw_affiliation_string': 'Case Western Reserve University Medical School, Cleveland, OH', 'institution_ids': ['https://openalex.org/I58956616']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5034124423', 'display_name': 'Norman Relkin', 'orcid': 'https://orcid.org/0000-0003-2495-950X'}, 'institutions': [{'id': 'https://openalex.org/I205783295', 'display_name': 'Cornell University', 'ror': 'https://ror.org/05bnh6r87', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I205783295']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Norman R. Relkin', 'raw_affiliation_strings': ['Cornell University Medical College, Manhasset, NY'], 'affiliations': [{'raw_affiliation_string': 'Cornell University Medical College, Manhasset, NY', 'institution_ids': ['https://openalex.org/I205783295']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5037912275', 'display_name': 'Richard C. Mohs', 'orcid': 'https://orcid.org/0000-0002-3765-6287'}, 'institutions': [{'id': 'https://openalex.org/I98704320', 'display_name': 'Icahn School of Medicine at Mount Sinai', 'ror': 'https://ror.org/04a9tmd77', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I1320796813', 'https://openalex.org/I98704320']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Richard C. Mohs', 'raw_affiliation_strings': ['Bronx VA Medical Center and Mount Sinai School of Medicine, Manhasset, NY'], 'affiliations': [{'raw_affiliation_string': 'Bronx VA Medical Center and Mount Sinai School of Medicine, Manhasset, NY', 'institution_ids': ['https://openalex.org/I98704320']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5021138224', 'display_name': 'Lena Lilius', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I28166907', 'display_name': 'Karolinska Institutet', 'ror': 'https://ror.org/056d84691', 'country_code': 'SE', 'type': 'education', 'lineage': ['https://openalex.org/I28166907']}, {'id': 'https://openalex.org/I1335113835', 'display_name': 'Karolinska University Hospital', 'ror': 'https://ror.org/00m8d6786', 'country_code': 'SE', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1335113835']}], 'countries': ['SE'], 'is_corresponding': False, 'raw_author_name': 'Lena Lilius', 'raw_affiliation_strings': ['Karolinska Institute, Huddinge University Hospital, Stockholm, Sweden'], 'affiliations': [{'raw_affiliation_string': 'Karolinska Institute, Huddinge University Hospital, Stockholm, Sweden', 'institution_ids': ['https://openalex.org/I28166907', 'https://openalex.org/I1335113835']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5107886274', 'display_name': 'Lars Lannfelt', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I28166907', 'display_name': 'Karolinska Institutet', 'ror': 'https://ror.org/056d84691', 'country_code': 'SE', 'type': 'education', 'lineage': ['https://openalex.org/I28166907']}, {'id': 'https://openalex.org/I1335113835', 'display_name': 'Karolinska University Hospital', 'ror': 'https://ror.org/00m8d6786', 'country_code': 'SE', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1335113835']}], 'countries': ['SE'], 'is_corresponding': False, 'raw_author_name': 'Lars Lannfelt', 'raw_affiliation_strings': ['Karolinska Institute, Huddinge University Hospital, Stockholm, Sweden'], 'affiliations': [{'raw_affiliation_string': 'Karolinska Institute, Huddinge University Hospital, Stockholm, Sweden', 'institution_ids': ['https://openalex.org/I28166907', 'https://openalex.org/I1335113835']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5110173475', 'display_name': 'John P. Blass', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I205783295', 'display_name': 'Cornell University', 'ror': 'https://ror.org/05bnh6r87', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I205783295']}, {'id': 'https://openalex.org/I4210117944', 'display_name': 'Burke Medical Research Institute', 'ror': 'https://ror.org/02sp1z620', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I4210117944']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'John P. Blass', 'raw_affiliation_strings': ['Burke Medical Research Institute, White Plains, NY', 'Cornell University Medical College, Manhasset, NY'], 'affiliations': [{'raw_affiliation_string': 'Cornell University Medical College, Manhasset, NY', 'institution_ids': ['https://openalex.org/I205783295']}, {'raw_affiliation_string': 'Burke Medical Research Institute, White Plains, NY', 'institution_ids': ['https://openalex.org/I4210117944']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 9, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3610, 'currency': 'USD', 'value_usd': 3610, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 5.33, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 39, 'citation_normalized_percentile': {'value': 0.696696, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 89, 'max': 90}, 'biblio': {'volume': '45', 'issue': '1', 'first_page': '48', 'last_page': '53'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12915', 'display_name': 'Biochemical Acid Research Studies', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1303', 'display_name': 'Biochemistry'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12915', 'display_name': 'Biochemical Acid Research Studies', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1303', 'display_name': 'Biochemistry'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10086', 'display_name': "Alzheimer's disease research and treatments", 'score': 0.9989, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10499', 'display_name': 'Folate and B Vitamins Research', 'score': 0.9932, 'subfield': {'id': 'https://openalex.org/subfields/2745', 'display_name': 'Rheumatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/apolipoprotein-e', 'display_name': 'Apolipoprotein E', 'score': 0.748281}], 'concepts': [{'id': 'https://openalex.org/C57089818', 'wikidata': 'https://www.wikidata.org/wiki/Q424728', 'display_name': 'Apolipoprotein E', 'level': 3, 'score': 0.748281}, {'id': 'https://openalex.org/C84597430', 'wikidata': 'https://www.wikidata.org/wiki/Q106227', 'display_name': 'Locus (genetics)', 'level': 3, 'score': 0.528974}, {'id': 'https://openalex.org/C180754005', 'wikidata': 'https://www.wikidata.org/wiki/Q80726', 'display_name': 'Allele', 'level': 3, 'score': 0.52022547}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.5082492}, {'id': 'https://openalex.org/C502032728', 'wikidata': 'https://www.wikidata.org/wiki/Q11081', 'display_name': "Alzheimer's disease", 'level': 3, 'score': 0.47670978}, {'id': 'https://openalex.org/C2779134260', 'wikidata': 'https://www.wikidata.org/wiki/Q12136', 'display_name': 'Disease', 'level': 2, 'score': 0.46837243}, {'id': 'https://openalex.org/C135763542', 'wikidata': 'https://www.wikidata.org/wiki/Q106016', 'display_name': 'Genotype', 'level': 3, 'score': 0.43692702}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.42291844}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.39895973}, {'id': 'https://openalex.org/C90924648', 'wikidata': 'https://www.wikidata.org/wiki/Q120569', 'display_name': 'Gastroenterology', 'level': 1, 'score': 0.36651668}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.32671267}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.25480497}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.23399395}], 'mesh': [{'descriptor_ui': 'D000217', 'descriptor_name': 'Acyltransferases', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D000544', 'descriptor_name': 'Alzheimer Disease', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D000544', 'descriptor_name': 'Alzheimer Disease', 'qualifier_ui': 'Q000453', 'qualifier_name': 'epidemiology', 'is_major_topic': True}, {'descriptor_ui': 'D000217', 'descriptor_name': 'Acyltransferases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000367', 'descriptor_name': 'Age Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000368', 'descriptor_name': 'Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000369', 'descriptor_name': 'Aged, 80 and over', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000483', 'descriptor_name': 'Alleles', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000544', 'descriptor_name': 'Alzheimer Disease', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D053327', 'descriptor_name': 'Apolipoprotein E4', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001057', 'descriptor_name': 'Apolipoproteins E', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D001057', 'descriptor_name': 'Apolipoproteins E', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005838', 'descriptor_name': 'Genotype', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011110', 'descriptor_name': 'Polymorphism, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015183', 'descriptor_name': 'Restriction Mapping', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012307', 'descriptor_name': 'Risk Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/1531-8249(199901)45:1<48::aid-art9>3.0.co;2-v', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S114530997', 'display_name': 'Annals of Neurology', 'issn_l': '0364-5134', 'issn': ['0364-5134', '1531-8249'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/9894876', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.69, 'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 42, 'referenced_works': ['https://openalex.org/W100914337', 'https://openalex.org/W10935351', 'https://openalex.org/W1558117629', 'https://openalex.org/W1963764092', 'https://openalex.org/W1965769560', 'https://openalex.org/W1968677128', 'https://openalex.org/W1969791593', 'https://openalex.org/W1971323773', 'https://openalex.org/W1973118540', 'https://openalex.org/W1978675778', 'https://openalex.org/W1981744647', 'https://openalex.org/W1983070519', 'https://openalex.org/W1984737558', 'https://openalex.org/W1989178832', 'https://openalex.org/W1996372359', 'https://openalex.org/W1999631936', 'https://openalex.org/W2001700140', 'https://openalex.org/W2001863186', 'https://openalex.org/W2006320762', 'https://openalex.org/W2006409771', 'https://openalex.org/W2019494456', 'https://openalex.org/W2023670690', 'https://openalex.org/W2030691153', 'https://openalex.org/W2046209489', 'https://openalex.org/W2046590674', 'https://openalex.org/W2049192526', 'https://openalex.org/W2071867775', 'https://openalex.org/W2089471300', 'https://openalex.org/W2092936855', 'https://openalex.org/W2092971739', 'https://openalex.org/W2093902719', 'https://openalex.org/W2104269538', 'https://openalex.org/W2111774300', 'https://openalex.org/W2112602336', 'https://openalex.org/W2115738813', 'https://openalex.org/W2135508686', 'https://openalex.org/W2140075873', 'https://openalex.org/W2152410944', 'https://openalex.org/W2156220037', 'https://openalex.org/W2156941821', 'https://openalex.org/W2161929150', 'https://openalex.org/W2171405125'], 'related_works': ['https://openalex.org/W858891458', 'https://openalex.org/W2416280054', 'https://openalex.org/W2413816897', 'https://openalex.org/W2386901427', 'https://openalex.org/W2361342090', 'https://openalex.org/W2125344851', 'https://openalex.org/W2124478268', 'https://openalex.org/W2042873259', 'https://openalex.org/W1989502778', 'https://openalex.org/W1956762270'], 'abstract_inverted_index': {'Annals': [0], 'of': [1, 13, 17, 103, 169, 236, 390, 456, 523, 625, 635, 648, 659, 697, 707, 745, 756, 764, 785, 796, 810, 825, 866], 'NeurologyVolume': [2], '45,': [3], 'Issue': [4], '1': [5], 'p.': [6], '48-53': [7, 880], 'Original': [8], 'Article': [9], 'Modulation': [10], 'by': [11, 61, 87, 110, 136, 153, 176, 199, 218, 243, 261, 281, 309, 348, 374, 397, 423, 440, 463, 486, 505, 530, 548, 568, 596, 771], 'DLST': [12, 688, 708, 726, 757, 861], 'the': [14, 641, 651, 691, 720, 725, 742, 807, 816, 842, 864], 'genetic': [15], 'risk': [16, 751], "Alzheimer's": [18, 684], 'disease': [19, 685], 'in': [20, 683, 711, 732, 740, 766, 803, 815, 830, 863, 868], 'a': [21, 656, 671, 749, 783, 855, 860], 'very': [22, 869], 'elderly': [23, 733, 870], 'population': [24], 'Kwan-Fu': [25, 31, 312, 318], 'Rex': [26, 32, 313, 319], 'Sheu': [27, 33, 314, 320], 'PhD,': [28, 66, 91, 115, 140, 157, 182, 223, 266, 287, 315, 353, 378, 402, 427, 444, 469, 510, 553, 574], 'Corresponding': [29, 316], 'Author': [30, 317], 'PhD': [34, 70, 94, 119, 143, 160, 187, 227, 270, 292, 321, 357, 381, 406, 430, 447, 474, 514, 557, 579], 'Burke': [35, 71, 120, 293, 322, 358, 407, 580], 'Medical': [36, 44, 48, 72, 80, 97, 121, 129, 145, 192, 211, 230, 294, 302, 323, 331, 335, 359, 367, 384, 408, 416, 432, 479, 498, 517, 581, 589], 'Research': [37, 49, 73, 122, 146, 295, 324, 336, 360, 409, 433, 582], 'Institute,': [38, 50, 74, 123, 252, 272, 296, 325, 337, 361, 410, 539, 559, 583], 'White': [39, 54, 75, 124, 297, 326, 341, 362, 411, 584], 'Plains,': [40, 55, 76, 125, 298, 327, 342, 363, 412, 585], 'NY': [41, 56, 77, 126, 299, 328, 343, 364, 413, 586], 'Cornell': [42, 78, 127, 209, 300, 329, 365, 414, 496, 587], 'University': [43, 79, 128, 163, 167, 191, 210, 254, 274, 301, 330, 366, 415, 450, 454, 478, 497, 541, 561, 588], 'College,': [45, 81, 130, 212, 303, 332, 368, 417, 499, 590], 'Manhasset,': [46, 82, 105, 131, 148, 171, 213, 238, 304, 333, 369, 392, 418, 435, 458, 500, 525, 591], 'NYBurke': [47, 334], '785': [51, 338], 'Mamaroneck': [52, 339], 'Avenue,': [53, 340], '10605Search': [57, 344], 'for': [58, 84, 107, 133, 150, 173, 196, 215, 240, 258, 278, 306, 345, 371, 394, 420, 437, 460, 483, 502, 527, 545, 565, 593, 753, 806], 'more': [59, 85, 108, 134, 151, 174, 197, 216, 241, 259, 279, 307, 346, 372, 395, 421, 438, 461, 484, 503, 528, 546, 566, 594], 'papers': [60, 86, 109, 135, 152, 175, 198, 217, 242, 260, 280, 308, 347, 373, 396, 422, 439, 462, 485, 504, 529, 547, 567, 595], 'this': [62, 88, 111, 137, 154, 177, 200, 219, 244, 262, 282, 310, 349, 375, 398, 424, 441, 464, 487, 506, 531, 549, 569, 597, 660, 826], 'authorAbraham': [63, 350], 'M.': [64, 68, 351, 355], 'Brown': [65, 69, 352, 356], 'Abraham': [67, 354], 'NYSearch': [83, 106, 132, 149, 172, 214, 239, 305, 370, 393, 419, 436, 459, 501, 526, 592], 'authorVahram': [89, 376], 'Haroutunian': [90, 93, 377, 380], 'Vahram': [92, 379], 'Bronx': [95, 228, 382, 515], 'VA': [96, 229, 383, 516], 'Center': [98, 231, 385, 518], 'and': [99, 232, 386, 519, 623, 627, 639, 646, 665, 699, 709, 714, 724, 727, 759, 828, 859], 'Mount': [100, 233, 387, 520], 'Sinai': [101, 234, 388, 521], 'School': [102, 168, 235, 389, 455, 522], 'Medicine,': [104, 170, 237, 391, 457, 524], 'authorBruce': [112, 399], 'S.': [113, 117, 400, 404], 'Kristal': [114, 118, 401, 405], 'Bruce': [116, 403], 'authorHoward': [138, 425], 'Thaler': [139, 142, 426, 429], 'Howard': [141, 428], 'Sloan-Kettering': [144, 431], 'Center,': [147, 434], 'authorMartin': [155, 442], 'Lesser': [156, 159, 443, 446], 'Martin': [158, 445], 'North': [161, 448], 'Shore': [162, 449], 'Hospital,': [164, 255, 275, 451, 542, 562], 'New': [165, 452], 'York': [166, 453], 'authorRajesh': [178, 465], 'N.': [179, 184, 466, 471], 'Kalaria': [180, 185, 467, 472], 'MD,': [181, 186, 204, 265, 269, 286, 291, 468, 473, 491, 552, 556, 573, 578], 'Rajesh': [183, 470], 'Case': [188, 475], 'Western': [189, 476], 'Reserve': [190, 477], 'School,': [193, 480], 'Cleveland,': [194, 481], 'OHSearch': [195, 482], 'authorNorman': [201, 488], 'R.': [202, 206, 489, 493], 'Relkin': [203, 207, 490, 494], 'Norman': [205, 492], 'MD': [208, 495], 'authorRichard': [220, 507], 'C.': [221, 225, 508, 512], 'Mohs': [222, 226, 509, 513], 'Richard': [224, 511], 'authorLena': [245, 532], 'Lilius': [246, 249, 533, 536], 'Bsc,': [247, 534], 'Lena': [248, 535], 'Bsc': [250, 537], 'Karolinska': [251, 271, 538, 558], 'Huddinge': [253, 273, 540, 560], 'Stockholm,': [256, 276, 543, 563], 'SwedenSearch': [257, 277, 544, 564], 'authorLars': [263, 550], 'Lannfelt': [264, 268, 551, 555], 'Lars': [267, 554], 'authorJohn': [283, 570], 'P.': [284, 289, 571, 576], 'Blass': [285, 290, 572, 577], 'John': [288, 575], 'author': [311, 598], 'First': [599], 'published:': [600], '31': [601], 'May': [602], '2001': [603], 'https://doi.org/10.1002/1531-8249(199901)45:1<48::AID-ART9>3.0.CO;2-VCitations:': [604], '25AboutPDF': [605], 'ToolsRequest': [606], 'permissionExport': [607], 'citationAdd': [608], 'to': [609, 631, 654, 762], 'favoritesTrack': [610], 'citation': [611], 'ShareShare': [612], 'Give': [613], 'accessShare': [614, 617], 'full': [615], 'text': [616], 'full-text': [618, 633, 657], 'accessPlease': [619], 'review': [620], 'our': [621], 'Terms': [622, 645], 'Conditions': [624, 647], 'Use': [626], 'check': [628], 'box': [629], 'below': [630, 653], 'share': [632, 655], 'version': [634, 658], 'article.I': [636], 'have': [637], 'read': [638], 'accept': [640], 'Wiley': [642], 'Online': [643], 'Library': [644], 'UseShareable': [649], 'LinkUse': [650], 'link': [652], 'article': [661], 'with': [662, 798], 'your': [663], 'friends': [664], 'colleagues.': [666], 'Learn': [667], 'more.Copy': [668], 'URL': [669], 'Share': [670], 'linkShare': [672], 'onFacebookTwitterLinkedInRedditWechat': [673], 'Abstract': [674], 'The': [675, 687], 'mitochondrial': [676], 'α-ketoglutarate': [677], 'dehydrogenase': [678], 'complex': [679], '(KGDHC)': [680], 'is': [681, 748], 'deficient': [682], '(AD).': [686], 'gene': [689], 'encodes': [690], 'core,': [692], 'dihydrolipoyl': [693], 'succinyltransferase': [694], '(DLST)': [695], 'component': [696], 'KGDHC,': [698], 'recent': [700], 'reports': [701], 'indicate': [702], 'an': [703, 794, 831], 'association': [704, 795], 'between': [705, 722, 857], 'polymorphisms': [706], 'AD': [710, 723, 738, 799, 867], 'both': [712], 'white': [713, 787, 839, 850], 'Japanese': [715], 'patients.': [716], 'We': [717], 'therefore': [718], 'examined': [719], 'relationship': [721, 856], 'apolipoprotein': [728], 'E': [729], '(APOE)': [730], 'genes': [731], '(89': [734], '±': [735], '7': [736], 'years)': [737], 'patients,': [739], 'whom': [741], 'ε4': [743], 'allele': [744, 809], 'APOE': [746], '(APOE4)': [747], 'weak': [750], 'factor': [752], 'AD.': [754], 'Polymorphisms': [755], '(A19,117G': [758], 'T19,183C),': [760], 'shown': [761], 'be': [763], 'interest': [765], 'previous': [767], 'studies,': [768], 'were': [769], 'analyzed': [770], 'restriction': [772], 'fragment': [773], 'length': [774], 'polymorphism': [775], 'analysis': [776], 'after': [777], 'polymerase': [778], 'chain': [779], 'reaction': [780], 'amplification.': [781], 'In': [782], 'series': [784, 833], '429': [786], 'subjects': [788, 840], 'from': [789, 841], 'two': [790], 'Jewish': [791, 843], 'nursing': [792, 844], 'homes,': [793], 'APOE4': [797, 858], 'was': [800], 'found': [801], 'only': [802], 'patients': [804], 'homozygous': [805], 'G,C': [808], 'DLST.': [811], 'Similar': [812], 'relationships': [813], 'occurred': [814], '"very': [817], 'elderly"': [818], '(≥85': [819], 'years,': [820], 'n': [821], '=': [822, 835], '302)': [823], 'subgroup': [824], 'series,': [827], 'also': [829], 'autopsy': [832], '(n': [834], '225)': [836], 'that': [837], 'included': [838], 'homes': [845], 'as': [846, 848], 'well': [847], 'other': [849], 'subjects.': [851, 871], 'These': [852], 'findings': [853], 'suggest': [854], 'locus': [862], 'pathogenesis': [865], 'Ann': [872], 'Neurol': [873], '1999;45:48–53': [874], 'Citing': [875], 'Literature': [876], 'Volume45,': [877], 'Issue1January': [878], '1999Pages': [879], 'RelatedInformation': [881]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2021227276', 'counts_by_year': [{'year': 2020, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 1}], 'updated_date': '2024-12-23T17:20:40.014037', 'created_date': '2016-06-24'}