Title: Inquiring Relation between Apolipoprotein E Gene Polymorphysm and the Alzheimer Disease
Abstract:Objective To study the distribution of Apo E gene in patients with Alzheimer desease, and analyse the relation between them . Methods ApoE genotyes of patients with Alzheimer desease and age-matched h...Objective To study the distribution of Apo E gene in patients with Alzheimer desease, and analyse the relation between them . Methods ApoE genotyes of patients with Alzheimer desease and age-matched healthy controls were determined by using the polymerphism technique,subsequently to require the ralation between ApoE allele and AD . Results ApoE e4 allele of patients with AD was 20.4%,which obviously was higher than 7.5% of cotrols, but e3 allele of patients with AD was 64.8%, which was lower than 83.2% of cotrols.Conclusions In ApoE allele, e4 allele is a genetic suscetible factor in AD,and e3 allele is a protection factor.Read More
Publication Year: 2001
Publication Date: 2001-01-01
Language: en
Type: article
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Cited By Count: 1
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