Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2016419822', 'doi': 'https://doi.org/10.1159/000365010', 'title': '45,X Karyotype in an Infertile Man: How Is This Possible?', 'display_name': '45,X Karyotype in an Infertile Man: How Is This Possible?', 'publication_year': 2014, 'publication_date': '2014-08-20', 'ids': {'openalex': 'https://openalex.org/W2016419822', 'doi': 'https://doi.org/10.1159/000365010', 'mag': '2016419822', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/25170625'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1159/000365010', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2232815', 'display_name': 'Urologia Internationalis', 'issn_l': '0042-1138', 'issn': ['0042-1138', '1423-0399'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310317820', 'host_organization_name': 'Karger Publishers', 'host_organization_lineage': ['https://openalex.org/P4310317820'], 'host_organization_lineage_names': ['Karger Publishers'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5070982793', 'display_name': 'Aline C.S. Amaro', 'orcid': 'https://orcid.org/0000-0001-8715-5774'}, 'institutions': [{'id': 'https://openalex.org/I4210143330', 'display_name': 'Faculdade de Medicina do ABC', 'ror': 'https://ror.org/047s7ag77', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I4210143330']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Aline Amaro', 'raw_affiliation_strings': ['Human Reproduction and Genetics Center, Faculdade de Medicina do ABC, Santo André, and'], 'affiliations': [{'raw_affiliation_string': 'Human Reproduction and Genetics Center, Faculdade de Medicina do ABC, Santo André, and', 'institution_ids': ['https://openalex.org/I4210143330']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5006865939', 'display_name': 'Fernanda Mafra', 'orcid': 'https://orcid.org/0000-0002-3962-2873'}, 'institutions': [{'id': 'https://openalex.org/I4210143330', 'display_name': 'Faculdade de Medicina do ABC', 'ror': 'https://ror.org/047s7ag77', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I4210143330']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Fernanda Abani Mafra', 'raw_affiliation_strings': ['Human Reproduction and Genetics Center, Faculdade de Medicina do ABC, Santo André, and'], 'affiliations': [{'raw_affiliation_string': 'Human Reproduction and Genetics Center, Faculdade de Medicina do ABC, Santo André, and', 'institution_ids': ['https://openalex.org/I4210143330']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5049225821', 'display_name': 'C. Pane', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210143330', 'display_name': 'Faculdade de Medicina do ABC', 'ror': 'https://ror.org/047s7ag77', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I4210143330']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Caio Eduardo Valada Pane', 'raw_affiliation_strings': ['Human Reproduction and Genetics Center, Faculdade de Medicina do ABC, Santo André, and'], 'affiliations': [{'raw_affiliation_string': 'Human Reproduction and Genetics Center, Faculdade de Medicina do ABC, Santo André, and', 'institution_ids': ['https://openalex.org/I4210143330']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5036721940', 'display_name': 'Leslie Domenici Kulikowski', 'orcid': 'https://orcid.org/0000-0003-2236-3956'}, 'institutions': [{'id': 'https://openalex.org/I17974374', 'display_name': 'Universidade de São Paulo', 'ror': 'https://ror.org/036rp1748', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I17974374']}, {'id': 'https://openalex.org/I4210143330', 'display_name': 'Faculdade de Medicina do ABC', 'ror': 'https://ror.org/047s7ag77', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I4210143330']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Leslie D. Kulikowski', 'raw_affiliation_strings': ['Department of Pathology, Laboratório de Citogenômica, LIM 03, Universidade de São Paulo, São Paulo, Brazil', 'Human Reproduction and Genetics Center, Faculdade de Medicina do ABC, Santo André, and'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, Laboratório de Citogenômica, LIM 03, Universidade de São Paulo, São Paulo, Brazil', 'institution_ids': ['https://openalex.org/I17974374']}, {'raw_affiliation_string': 'Human Reproduction and Genetics Center, Faculdade de Medicina do ABC, Santo André, and', 'institution_ids': ['https://openalex.org/I4210143330']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5051467144', 'display_name': 'Bianca Bianco', 'orcid': 'https://orcid.org/0000-0001-8669-3562'}, 'institutions': [{'id': 'https://openalex.org/I4210143330', 'display_name': 'Faculdade de Medicina do ABC', 'ror': 'https://ror.org/047s7ag77', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I4210143330']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Bianca Bianco', 'raw_affiliation_strings': ['Human Reproduction and Genetics Center, Faculdade de Medicina do ABC, Santo André, and'], 'affiliations': [{'raw_affiliation_string': 'Human Reproduction and Genetics Center, Faculdade de Medicina do ABC, Santo André, and', 'institution_ids': ['https://openalex.org/I4210143330']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103030111', 'display_name': 'Caio Parente Barbosa', 'orcid': 'https://orcid.org/0000-0002-2922-0264'}, 'institutions': [{'id': 'https://openalex.org/I4210143330', 'display_name': 'Faculdade de Medicina do ABC', 'ror': 'https://ror.org/047s7ag77', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I4210143330']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Caio Parente Barbosa', 'raw_affiliation_strings': ['Human Reproduction and Genetics Center, Faculdade de Medicina do ABC, Santo André, and'], 'affiliations': [{'raw_affiliation_string': 'Human Reproduction and Genetics Center, Faculdade de Medicina do ABC, Santo André, and', 'institution_ids': ['https://openalex.org/I4210143330']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5027754051', 'display_name': 'Denise Maria Christofolini', 'orcid': 'https://orcid.org/0000-0001-9589-6417'}, 'institutions': [{'id': 'https://openalex.org/I4210143330', 'display_name': 'Faculdade de Medicina do ABC', 'ror': 'https://ror.org/047s7ag77', 'country_code': 'BR', 'type': 'education', 'lineage': ['https://openalex.org/I4210143330']}], 'countries': ['BR'], 'is_corresponding': False, 'raw_author_name': 'Denise Maria Christofolini', 'raw_affiliation_strings': ['Human Reproduction and Genetics Center, Faculdade de Medicina do ABC, Santo André, and'], 'affiliations': [{'raw_affiliation_string': 'Human Reproduction and Genetics Center, Faculdade de Medicina do ABC, Santo André, and', 'institution_ids': ['https://openalex.org/I4210143330']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.393, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 7, 'citation_normalized_percentile': {'value': 0.611409, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 83, 'max': 84}, 'biblio': {'volume': '94', 'issue': '4', 'first_page': '488', 'last_page': '490'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11077', 'display_name': 'Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11077', 'display_name': 'Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11956', 'display_name': 'Sexual Differentiation and Disorders', 'score': 0.9944, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10116', 'display_name': 'Sperm and Testicular Function', 'score': 0.9846, 'subfield': {'id': 'https://openalex.org/subfields/2743', 'display_name': 'Reproductive Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/azoospermia-factor', 'display_name': 'Azoospermia factor', 'score': 0.47107854}], 'concepts': [{'id': 'https://openalex.org/C53226629', 'wikidata': 'https://www.wikidata.org/wiki/Q189967', 'display_name': 'Karyotype', 'level': 4, 'score': 0.93757653}, {'id': 'https://openalex.org/C2777420699', 'wikidata': 'https://www.wikidata.org/wiki/Q794026', 'display_name': 'Azoospermia', 'level': 4, 'score': 0.7261617}, {'id': 'https://openalex.org/C2777688143', 'wikidata': 'https://www.wikidata.org/wiki/Q179399', 'display_name': 'Infertility', 'level': 3, 'score': 0.62255657}, {'id': 'https://openalex.org/C49105822', 'wikidata': 'https://www.wikidata.org/wiki/Q176996', 'display_name': 'Polymerase chain reaction', 'level': 3, 'score': 0.55419785}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.55276555}, {'id': 'https://openalex.org/C2777542201', 'wikidata': 'https://www.wikidata.org/wiki/Q1336182', 'display_name': 'Fluorescence in situ hybridization', 'level': 4, 'score': 0.55171216}, {'id': 'https://openalex.org/C174475383', 'wikidata': 'https://www.wikidata.org/wiki/Q246128', 'display_name': 'Cytogenetics', 'level': 4, 'score': 0.48776823}, {'id': 'https://openalex.org/C2776029846', 'wikidata': 'https://www.wikidata.org/wiki/Q4832829', 'display_name': 'Azoospermia factor', 'level': 5, 'score': 0.47107854}, {'id': 'https://openalex.org/C29456083', 'wikidata': 'https://www.wikidata.org/wiki/Q1221899', 'display_name': 'Gynecology', 'level': 1, 'score': 0.4470411}, {'id': 'https://openalex.org/C30481170', 'wikidata': 'https://www.wikidata.org/wiki/Q37748', 'display_name': 'Chromosome', 'level': 3, 'score': 0.443982}, {'id': 'https://openalex.org/C2777338322', 'wikidata': 'https://www.wikidata.org/wiki/Q280156', 'display_name': 'Male infertility', 'level': 4, 'score': 0.4214816}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.39649597}, {'id': 'https://openalex.org/C16685009', 'wikidata': 'https://www.wikidata.org/wiki/Q335057', 'display_name': 'Andrology', 'level': 1, 'score': 0.37720636}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.29139718}, {'id': 'https://openalex.org/C2779234561', 'wikidata': 'https://www.wikidata.org/wiki/Q11995', 'display_name': 'Pregnancy', 'level': 2, 'score': 0.112285286}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.08679426}], 'mesh': [{'descriptor_ui': 'D041321', 'descriptor_name': 'Chromosomes, Human, X', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D041322', 'descriptor_name': 'Chromosomes, Human, Y', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D005298', 'descriptor_name': 'Fertility', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D050174', 'descriptor_name': 'Genetic Diseases, Y-Linked', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D007248', 'descriptor_name': 'Infertility, Male', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005298', 'descriptor_name': 'Fertility', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D050174', 'descriptor_name': 'Genetic Diseases, Y-Linked', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': False}, {'descriptor_ui': 'D050174', 'descriptor_name': 'Genetic Diseases, Y-Linked', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': False}, {'descriptor_ui': 'D050174', 'descriptor_name': 'Genetic Diseases, Y-Linked', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020022', 'descriptor_name': 'Genetic Predisposition to Disease', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017404', 'descriptor_name': 'In Situ Hybridization, Fluorescence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007248', 'descriptor_name': 'Infertility, Male', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': False}, {'descriptor_ui': 'D007248', 'descriptor_name': 'Infertility, Male', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': False}, {'descriptor_ui': 'D007248', 'descriptor_name': 'Infertility, Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007621', 'descriptor_name': 'Karyotyping', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D025202', 'descriptor_name': 'Molecular Diagnostic Techniques', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010641', 'descriptor_name': 'Phenotype', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016133', 'descriptor_name': 'Polymerase Chain Reaction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011379', 'descriptor_name': 'Prognosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1159/000365010', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2232815', 'display_name': 'Urologia Internationalis', 'issn_l': '0042-1138', 'issn': ['0042-1138', '1423-0399'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310317820', 'host_organization_name': 'Karger Publishers', 'host_organization_lineage': ['https://openalex.org/P4310317820'], 'host_organization_lineage_names': ['Karger Publishers'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/25170625', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.5, 'id': 'https://metadata.un.org/sdg/2', 'display_name': 'Zero hunger'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 9, 'referenced_works': ['https://openalex.org/W1972221389', 'https://openalex.org/W1972493583', 'https://openalex.org/W1985908166', 'https://openalex.org/W2046570267', 'https://openalex.org/W2076450739', 'https://openalex.org/W2081462356', 'https://openalex.org/W2083851456', 'https://openalex.org/W2156147446', 'https://openalex.org/W2171619679'], 'related_works': ['https://openalex.org/W4308769337', 'https://openalex.org/W2401088391', 'https://openalex.org/W2395478764', 'https://openalex.org/W2391129736', 'https://openalex.org/W2368704277', 'https://openalex.org/W2364379034', 'https://openalex.org/W2348719406', 'https://openalex.org/W2262973066', 'https://openalex.org/W2158235155', 'https://openalex.org/W2121791548'], 'abstract_inverted_index': {'The': [0], 'case': [1], 'was': [2], 'male,': [3], '32': [4], 'years': [5], 'old,': [6], 'with': [7], 'a': [8, 65], 'nonobstructive': [9], 'azoospermia': [10], 'diagnosis': [11], 'and': [12, 24, 31, 58], 'an': [13], 'initial': [14], '45,X': [15], 'karyotype.': [16], 'We': [17], 'evaluated': [18], 'by': [19], 'classical': [20], 'cytogenetic': [21, 66], 'methods,': [22], 'C': [23], 'NOR': [25], 'banding,': [26], 'fluorescent': [27], 'in': [28, 68], 'situ': [29], 'hybridization,': [30], 'polymerase': [32], 'chain': [33], 'reaction': [34], 'investigations.': [35], 'After': [36], 'investigation,': [37], 'we': [38], 'found': [39], 'the': [40], 'following': [41], 'karyotype:': [42], '45,X,dic(Y;22)(q11.223;p11.2).': [43], 'This': [44], 'investigation': [45], 'contributes': [46], 'to': [47, 63], 'our': [48], 'understanding': [49], 'of': [50], 'how': [51, 59], 'chromosome': [52], 'rearrangements': [53], 'can': [54], 'influence': [55], 'fertility': [56], 'processes': [57], 'important': [60], 'it': [61], 'is': [62], 'perform': [64], 'analysis': [67], 'infertility': [69], 'cases.': [70]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2016419822', 'counts_by_year': [{'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 2}, {'year': 2013, 'cited_by_count': 1}], 'updated_date': '2025-01-04T13:56:40.397469', 'created_date': '2016-06-24'}