Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2395478764', 'doi': 'https://doi.org/10.3760/cma.j.issn.1003-9406.2012.02.015', 'title': '[Screening and clinical phenotype analysis of microdeletions of azoospermia factor region on Y chromosome in 1011 infertile men].', 'display_name': '[Screening and clinical phenotype analysis of microdeletions of azoospermia factor region on Y chromosome in 1011 infertile men].', 'publication_year': 2012, 'publication_date': '2012-04-01', 'ids': {'openalex': 'https://openalex.org/W2395478764', 'doi': 'https://doi.org/10.3760/cma.j.issn.1003-9406.2012.02.015', 'mag': '2395478764', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/22487830'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/22487830', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5101707465', 'display_name': 'Li Fu', 'orcid': 'https://orcid.org/0000-0002-3396-4901'}, 'institutions': [{'id': 'https://openalex.org/I24185976', 'display_name': 'Sichuan University', 'ror': 'https://ror.org/011ashp19', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I24185976']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Li Fu', 'raw_affiliation_strings': ["Institute of Medical Genetics, Sichuan University, Chengdu, Sichuan, People's Republic of China."], 'affiliations': [{'raw_affiliation_string': "Institute of Medical Genetics, Sichuan University, Chengdu, Sichuan, People's Republic of China.", 'institution_ids': ['https://openalex.org/I24185976']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5025278311', 'display_name': 'Xianping Ding', 'orcid': 'https://orcid.org/0000-0003-1555-5028'}, 'institutions': [{'id': 'https://openalex.org/I24185976', 'display_name': 'Sichuan University', 'ror': 'https://ror.org/011ashp19', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I24185976']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Xian-ping Ding', 'raw_affiliation_strings': ['Key Laboratory of Bio-resources and Eco-environment, Ministry of Education Institute of Medical Genetics, College of Life Science, Sichuan University, Chengdu, Sichuan 610064, P. R. China.'], 'affiliations': [{'raw_affiliation_string': 'Key Laboratory of Bio-resources and Eco-environment, Ministry of Education Institute of Medical Genetics, College of Life Science, Sichuan University, Chengdu, Sichuan 610064, P. R. China.', 'institution_ids': ['https://openalex.org/I24185976']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5018288473', 'display_name': 'Mengjie Shen', 'orcid': 'https://orcid.org/0000-0002-0728-7353'}, 'institutions': [{'id': 'https://openalex.org/I24185976', 'display_name': 'Sichuan University', 'ror': 'https://ror.org/011ashp19', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I24185976']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Meng-jie Shen', 'raw_affiliation_strings': ['Key Laboratory of Bio-resources and Eco-environment, Ministry of Education Institute of Medical Genetics, College of Life Science, Sichuan University, Chengdu, Sichuan 610064, P. R. China.'], 'affiliations': [{'raw_affiliation_string': 'Key Laboratory of Bio-resources and Eco-environment, Ministry of Education Institute of Medical Genetics, College of Life Science, Sichuan University, Chengdu, Sichuan 610064, P. R. China.', 'institution_ids': ['https://openalex.org/I24185976']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100386697', 'display_name': 'Chuang Li', 'orcid': 'https://orcid.org/0000-0001-8346-9434'}, 'institutions': [{'id': 'https://openalex.org/I24185976', 'display_name': 'Sichuan University', 'ror': 'https://ror.org/011ashp19', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I24185976']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Chuang Li', 'raw_affiliation_strings': ['Key Laboratory of Bio-resources and Eco-environment, Ministry of Education Institute of Medical Genetics, College of Life Science, Sichuan University, Chengdu, Sichuan 610064, P. R. China.'], 'affiliations': [{'raw_affiliation_string': 'Key Laboratory of Bio-resources and Eco-environment, Ministry of Education Institute of Medical Genetics, College of Life Science, Sichuan University, Chengdu, Sichuan 610064, P. R. China.', 'institution_ids': ['https://openalex.org/I24185976']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5112479351', 'display_name': 'Shuangshuang Nie', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I24185976', 'display_name': 'Sichuan University', 'ror': 'https://ror.org/011ashp19', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I24185976']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Shuang-shuang Nie', 'raw_affiliation_strings': ['Key Laboratory of Bio-resources and Eco-environment, Ministry of Education Institute of Medical Genetics, College of Life Science, Sichuan University, Chengdu, Sichuan 610064, P. R. China.'], 'affiliations': [{'raw_affiliation_string': 'Key Laboratory of Bio-resources and Eco-environment, Ministry of Education Institute of Medical Genetics, College of Life Science, Sichuan University, Chengdu, Sichuan 610064, P. R. China.', 'institution_ids': ['https://openalex.org/I24185976']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5088356815', 'display_name': 'Qiang Quan', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I24185976', 'display_name': 'Sichuan University', 'ror': 'https://ror.org/011ashp19', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I24185976']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Qiang Quan', 'raw_affiliation_strings': ['Key Laboratory of Bio-resources and Eco-environment, Ministry of Education Institute of Medical Genetics, College of Life Science, Sichuan University, Chengdu, Sichuan 610064, P. R. China.'], 'affiliations': [{'raw_affiliation_string': 'Key Laboratory of Bio-resources and Eco-environment, Ministry of Education Institute of Medical Genetics, College of Life Science, Sichuan University, Chengdu, Sichuan 610064, P. R. China.', 'institution_ids': ['https://openalex.org/I24185976']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.375, 'has_fulltext': False, 'cited_by_count': 5, 'citation_normalized_percentile': {'value': 0.669853, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 80, 'max': 81}, 'biblio': {'volume': '29', 'issue': '2', 'first_page': '184', 'last_page': '7'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11077', 'display_name': 'Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities', 'score': 0.995, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11077', 'display_name': 'Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities', 'score': 0.995, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11956', 'display_name': 'Sexual Differentiation and Disorders', 'score': 0.9722, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/azoospermia-factor', 'display_name': 'Azoospermia factor', 'score': 0.92641926}, {'id': 'https://openalex.org/keywords/oligospermia', 'display_name': 'Oligospermia', 'score': 0.8278477}, {'id': 'https://openalex.org/keywords/sequence-tagged-site', 'display_name': 'Sequence-tagged site', 'score': 0.45417285}, {'id': 'https://openalex.org/keywords/y-chromosome-microdeletion', 'display_name': 'Y chromosome microdeletion', 'score': 0.4122935}], 'concepts': [{'id': 'https://openalex.org/C2776029846', 'wikidata': 'https://www.wikidata.org/wiki/Q4832829', 'display_name': 'Azoospermia factor', 'level': 5, 'score': 0.92641926}, {'id': 'https://openalex.org/C2777420699', 'wikidata': 'https://www.wikidata.org/wiki/Q794026', 'display_name': 'Azoospermia', 'level': 4, 'score': 0.9019847}, {'id': 'https://openalex.org/C2777358149', 'wikidata': 'https://www.wikidata.org/wiki/Q1876491', 'display_name': 'Oligospermia', 'level': 5, 'score': 0.8278477}, {'id': 'https://openalex.org/C2777338322', 'wikidata': 'https://www.wikidata.org/wiki/Q280156', 'display_name': 'Male infertility', 'level': 4, 'score': 0.7321454}, {'id': 'https://openalex.org/C2780246931', 'wikidata': 'https://www.wikidata.org/wiki/Q202771', 'display_name': 'Y chromosome', 'level': 3, 'score': 0.5752737}, {'id': 'https://openalex.org/C2777688143', 'wikidata': 'https://www.wikidata.org/wiki/Q179399', 'display_name': 'Infertility', 'level': 3, 'score': 0.54016805}, {'id': 'https://openalex.org/C135763542', 'wikidata': 'https://www.wikidata.org/wiki/Q106016', 'display_name': 'Genotype', 'level': 3, 'score': 0.52522516}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.4927447}, {'id': 'https://openalex.org/C206625514', 'wikidata': 'https://www.wikidata.org/wiki/Q2068713', 'display_name': 'Sequence-tagged site', 'level': 5, 'score': 0.45417285}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.4317538}, {'id': 'https://openalex.org/C2780424099', 'wikidata': 'https://www.wikidata.org/wiki/Q8046191', 'display_name': 'Y chromosome microdeletion', 'level': 5, 'score': 0.4122935}, {'id': 'https://openalex.org/C16685009', 'wikidata': 'https://www.wikidata.org/wiki/Q335057', 'display_name': 'Andrology', 'level': 1, 'score': 0.35854846}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.30679005}, {'id': 'https://openalex.org/C30481170', 'wikidata': 'https://www.wikidata.org/wiki/Q37748', 'display_name': 'Chromosome', 'level': 3, 'score': 0.26546857}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.21321571}, {'id': 'https://openalex.org/C2779234561', 'wikidata': 'https://www.wikidata.org/wiki/Q11995', 'display_name': 'Pregnancy', 'level': 2, 'score': 0.09658572}, {'id': 'https://openalex.org/C122735190', 'wikidata': 'https://www.wikidata.org/wiki/Q715789', 'display_name': 'Gene mapping', 'level': 4, 'score': 0.060253263}], 'mesh': [{'descriptor_ui': 'D053713', 'descriptor_name': 'Azoospermia', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D002872', 'descriptor_name': 'Chromosome Deletion', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D041322', 'descriptor_name': 'Chromosomes, Human, Y', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D007248', 'descriptor_name': 'Infertility, Male', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D053713', 'descriptor_name': 'Azoospermia', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D056726', 'descriptor_name': 'Genetic Association Studies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D056726', 'descriptor_name': 'Genetic Association Studies', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007248', 'descriptor_name': 'Infertility, Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010641', 'descriptor_name': 'Phenotype', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D055815', 'descriptor_name': 'Young Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/22487830', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W3203330648', 'https://openalex.org/W2903352915', 'https://openalex.org/W2473289660', 'https://openalex.org/W2395478764', 'https://openalex.org/W2369862157', 'https://openalex.org/W2366655529', 'https://openalex.org/W2184515759', 'https://openalex.org/W2041723064', 'https://openalex.org/W2034714413', 'https://openalex.org/W1579206584'], 'abstract_inverted_index': {'To': [0], 'investigate': [1], 'the': [2, 60, 89, 104, 112, 137, 174, 188], 'prevalence': [3, 53], 'and': [4, 46, 59, 69, 101, 129, 155, 177], 'subtypes': [5], 'of': [6, 33, 43, 49, 54, 103, 136, 158], 'microdeletions': [7, 35, 55], 'in': [8, 13, 18, 36, 66, 72, 111, 117, 122, 144], 'azoospermia': [9, 45, 68], 'factor': [10], '(AZF)': [11], 'region': [12, 139], 'infertile': [14, 38], 'men': [15, 39], 'from': [16], 'Sichuan': [17], 'order': [19], 'to': [20, 27], 'correlate': [21], 'genotypes': [22], 'with': [23, 82, 97, 106, 125, 132, 149, 160, 165], 'phenotypes.Multiplex-PCR': [24], 'was': [25, 56, 88, 120], 'used': [26], 'detect': [28], 'sequence': [29], 'tagged': [30], 'sites': [31], '(STS)': [32], 'AZF': [34], '1011': [37], 'including': [40], '713': [41], 'cases': [42, 48, 124, 148, 159], 'non-obstructive': [44, 67], '298': [47], 'severe': [50, 73], 'oligospermia.The': [51], 'overall': [52], '10.48%': [57], '(106/1011),': [58], 'deletion': [61, 86, 108, 128, 162], 'rates': [62], 'were': [63, 80, 95, 140, 163], '11.08%': [64], '(79/713)': [65], '9.06%': [70], '(27/298)': [71], 'oligospermia.': [74], 'Complete': [75], 'AZFa': [76, 151], 'or': [77, 152], 'AZFb': [78, 127, 153], 'deletions': [79, 94, 154], 'associated': [81, 96, 164], 'azoospermia,': [83], 'whereas': [84], 'AZFc': [85, 138, 161], '(60.38%)': [87], 'most': [90, 141], 'frequent': [91], 'deletion.': [92], 'The': [93], 'variable': [98], 'spermatogenic': [99], 'phenotypes,': [100], '37.50%': [102], 'patients': [105], 'a': [107, 156, 184], 'had': [109], 'sperms': [110], 'ejaculate.': [113], 'A': [114], 'mild': [115], 'decline': [116], 'sperm': [118], 'concentration': [119], 'found': [121, 143], 'two': [123], 'partial': [126, 133], 'one': [130], 'case': [131], 'AZFb-c': [134], 'deletion.Deletions': [135], 'commonly': [142], 'our': [145], 'patients.': [146], 'All': [147], 'complete': [150], 'proportion': [157], 'azoospermia.': [166], 'Our': [167], 'study': [168], 'has': [169, 183], 'provided': [170], 'more': [171], 'insight': [172], 'into': [173], 'genotype-phenotype': [175], 'correlation,': [176], 'confirmed': [178], 'that': [179], 'Yq': [180], 'microdeletion': [181], 'screening': [182], 'significant': [185], 'value': [186], 'for': [187, 190], 'diagnosis': [189], 'male': [191], 'infertility.': [192]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2395478764', 'counts_by_year': [{'year': 2020, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 1}], 'updated_date': '2024-12-24T12:27:48.067589', 'created_date': '2016-06-24'}