Title: Effect of Vitamin B1 and Cocarboxylase on Synthesis of Acetylcholine.
Abstract: 1. The synthesis of acetylcholine in vitro in the presence of thiamine chloride and thiamine pyrophosphate was investigated. 2. Both thiamine chloride and thiamine pyrophosphate, in concentrations of 3.10-6 M and 2.10-6 M respectively, slightly increased the synthesis of acetylcholine (average 10%). 3. The thiamine compounds in higher concentrations depressed the synthesis of acetylcholine. Thiamine chloride is a more potent depressor than thiamine pyrophosphate.
Publication Year: 1944
Publication Date: 1944-06-01
Language: en
Type: article
Indexed In: ['crossref']
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Cited By Count: 5
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