Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2007931369', 'doi': 'https://doi.org/10.1038/316820a0', 'title': 'Detection of P-glycoprotein in multidrug-resistant cell lines by monoclonal antibodies', 'display_name': 'Detection of P-glycoprotein in multidrug-resistant cell lines by monoclonal antibodies', 'publication_year': 1985, 'publication_date': '1985-08-01', 'ids': {'openalex': 'https://openalex.org/W2007931369', 'doi': 'https://doi.org/10.1038/316820a0', 'mag': '2007931369', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/2412130'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1038/316820a0', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S137773608', 'display_name': 'Nature', 'issn_l': '0028-0836', 'issn': ['0028-0836', '1476-4687'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319908', 'host_organization_name': 'Nature Portfolio', 'host_organization_lineage': ['https://openalex.org/P4310319908', 'https://openalex.org/P4310319965'], 'host_organization_lineage_names': ['Nature Portfolio', 'Springer Nature'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5067951639', 'display_name': 'Norbert Kartner', 'orcid': 'https://orcid.org/0000-0002-8548-9479'}, 'institutions': [{'id': 'https://openalex.org/I2802654988', 'display_name': 'Princess Margaret Cancer Centre', 'ror': 'https://ror.org/03zayce58', 'country_code': 'CA', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1325899441', 'https://openalex.org/I2802654988']}, {'id': 'https://openalex.org/I2801345345', 'display_name': 'Cancer Institute (WIA)', 'ror': 'https://ror.org/01tc10z29', 'country_code': 'IN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2801345345']}, {'id': 'https://openalex.org/I185261750', 'display_name': 'University of Toronto', 'ror': 'https://ror.org/03dbr7087', 'country_code': 'CA', 'type': 'education', 'lineage': ['https://openalex.org/I185261750']}, {'id': 'https://openalex.org/I112260969', 'display_name': 'Ontario Institute for Cancer Research', 'ror': 'https://ror.org/043q8yx54', 'country_code': 'CA', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I112260969']}], 'countries': ['CA', 'IN'], 'is_corresponding': False, 'raw_author_name': 'Norbert Kartner', 'raw_affiliation_strings': ['Department of Medical Biophysics, University of Toronto, Toronto, Canada', 'Ontario Cancer Institute, Princess Margaret Hospital,'], 'affiliations': [{'raw_affiliation_string': 'Ontario Cancer Institute, Princess Margaret Hospital,', 'institution_ids': ['https://openalex.org/I2802654988', 'https://openalex.org/I2801345345', 'https://openalex.org/I112260969']}, {'raw_affiliation_string': 'Department of Medical Biophysics, University of Toronto, Toronto, Canada', 'institution_ids': ['https://openalex.org/I185261750']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5006478319', 'display_name': 'Deanna Evernden-Porelle', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I185261750', 'display_name': 'University of Toronto', 'ror': 'https://ror.org/03dbr7087', 'country_code': 'CA', 'type': 'education', 'lineage': ['https://openalex.org/I185261750']}, {'id': 'https://openalex.org/I112260969', 'display_name': 'Ontario Institute for Cancer Research', 'ror': 'https://ror.org/043q8yx54', 'country_code': 'CA', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I112260969']}, {'id': 'https://openalex.org/I2802654988', 'display_name': 'Princess Margaret Cancer Centre', 'ror': 'https://ror.org/03zayce58', 'country_code': 'CA', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1325899441', 'https://openalex.org/I2802654988']}, {'id': 'https://openalex.org/I2801345345', 'display_name': 'Cancer Institute (WIA)', 'ror': 'https://ror.org/01tc10z29', 'country_code': 'IN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2801345345']}], 'countries': ['CA', 'IN'], 'is_corresponding': False, 'raw_author_name': 'Deanna Evernden-Porelle', 'raw_affiliation_strings': ['Department of Medical Biophysics, University of Toronto, Toronto, Canada', 'Ontario Cancer Institute, Princess Margaret Hospital,'], 'affiliations': [{'raw_affiliation_string': 'Department of Medical Biophysics, University of Toronto, Toronto, Canada', 'institution_ids': ['https://openalex.org/I185261750']}, {'raw_affiliation_string': 'Ontario Cancer Institute, Princess Margaret Hospital,', 'institution_ids': ['https://openalex.org/I112260969', 'https://openalex.org/I2802654988', 'https://openalex.org/I2801345345']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5084558412', 'display_name': 'Grace Bradley', 'orcid': 'https://orcid.org/0000-0002-9008-8696'}, 'institutions': [{'id': 'https://openalex.org/I185261750', 'display_name': 'University of Toronto', 'ror': 'https://ror.org/03dbr7087', 'country_code': 'CA', 'type': 'education', 'lineage': ['https://openalex.org/I185261750']}, {'id': 'https://openalex.org/I112260969', 'display_name': 'Ontario Institute for Cancer Research', 'ror': 'https://ror.org/043q8yx54', 'country_code': 'CA', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I112260969']}, {'id': 'https://openalex.org/I2802654988', 'display_name': 'Princess Margaret Cancer Centre', 'ror': 'https://ror.org/03zayce58', 'country_code': 'CA', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1325899441', 'https://openalex.org/I2802654988']}, {'id': 'https://openalex.org/I2801345345', 'display_name': 'Cancer Institute (WIA)', 'ror': 'https://ror.org/01tc10z29', 'country_code': 'IN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2801345345']}], 'countries': ['CA', 'IN'], 'is_corresponding': False, 'raw_author_name': 'Grace Bradley', 'raw_affiliation_strings': ['Department of Medical Biophysics, University of Toronto, Toronto, Canada', 'Ontario Cancer Institute, Princess Margaret Hospital,'], 'affiliations': [{'raw_affiliation_string': 'Department of Medical Biophysics, University of Toronto, Toronto, Canada', 'institution_ids': ['https://openalex.org/I185261750']}, {'raw_affiliation_string': 'Ontario Cancer Institute, Princess Margaret Hospital,', 'institution_ids': ['https://openalex.org/I112260969', 'https://openalex.org/I2802654988', 'https://openalex.org/I2801345345']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5051827745', 'display_name': 'Victor Ling', 'orcid': 'https://orcid.org/0000-0002-8279-0645'}, 'institutions': [{'id': 'https://openalex.org/I185261750', 'display_name': 'University of Toronto', 'ror': 'https://ror.org/03dbr7087', 'country_code': 'CA', 'type': 'education', 'lineage': ['https://openalex.org/I185261750']}, {'id': 'https://openalex.org/I112260969', 'display_name': 'Ontario Institute for Cancer Research', 'ror': 'https://ror.org/043q8yx54', 'country_code': 'CA', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I112260969']}, {'id': 'https://openalex.org/I2802654988', 'display_name': 'Princess Margaret Cancer Centre', 'ror': 'https://ror.org/03zayce58', 'country_code': 'CA', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1325899441', 'https://openalex.org/I2802654988']}, {'id': 'https://openalex.org/I2801345345', 'display_name': 'Cancer Institute (WIA)', 'ror': 'https://ror.org/01tc10z29', 'country_code': 'IN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2801345345']}], 'countries': ['CA', 'IN'], 'is_corresponding': False, 'raw_author_name': 'Victor Ling', 'raw_affiliation_strings': ['Department of Medical Biophysics, University of Toronto, Toronto, Canada', 'Ontario Cancer Institute, Princess Margaret Hospital,'], 'affiliations': [{'raw_affiliation_string': 'Department of Medical Biophysics, University of Toronto, Toronto, Canada', 'institution_ids': ['https://openalex.org/I185261750']}, {'raw_affiliation_string': 'Ontario Cancer Institute, Princess Margaret Hospital,', 'institution_ids': ['https://openalex.org/I112260969', 'https://openalex.org/I2802654988', 'https://openalex.org/I2801345345']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 4, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 9750, 'currency': 'EUR', 'value_usd': 11690, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 26.875, 'has_fulltext': False, 'cited_by_count': 923, 'citation_normalized_percentile': {'value': 0.999792, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '316', 'issue': '6031', 'first_page': '820', 'last_page': '823'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10570', 'display_name': 'Mechanisms of Multidrug Resistance in Cancer', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10570', 'display_name': 'Mechanisms of Multidrug Resistance in Cancer', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10602', 'display_name': 'Glycosylation in Health and Disease', 'score': 0.9967, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11845', 'display_name': 'DNA Topoisomerases: Structure, Function, and Inhibition', 'score': 0.9865, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/p-glycoprotein', 'display_name': 'P-glycoprotein', 'score': 0.562804}, {'id': 'https://openalex.org/keywords/multidrug-resistance', 'display_name': 'Multidrug Resistance', 'score': 0.538365}], 'concepts': [{'id': 'https://openalex.org/C542903549', 'wikidata': 'https://www.wikidata.org/wiki/Q422248', 'display_name': 'Monoclonal antibody', 'level': 3, 'score': 0.88087285}, {'id': 'https://openalex.org/C108625454', 'wikidata': 'https://www.wikidata.org/wiki/Q187126', 'display_name': 'Glycoprotein', 'level': 2, 'score': 0.73901814}, {'id': 'https://openalex.org/C195616568', 'wikidata': 'https://www.wikidata.org/wiki/Q128711', 'display_name': 'Epitope', 'level': 3, 'score': 0.7324782}, {'id': 'https://openalex.org/C133936738', 'wikidata': 'https://www.wikidata.org/wiki/Q643839', 'display_name': 'Multiple drug resistance', 'level': 3, 'score': 0.72512126}, {'id': 'https://openalex.org/C2778707650', 'wikidata': 'https://www.wikidata.org/wiki/Q412902', 'display_name': 'P-glycoprotein', 'level': 4, 'score': 0.6684093}, {'id': 'https://openalex.org/C159654299', 'wikidata': 'https://www.wikidata.org/wiki/Q79460', 'display_name': 'Antibody', 'level': 2, 'score': 0.66603255}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.5150661}, {'id': 'https://openalex.org/C81885089', 'wikidata': 'https://www.wikidata.org/wiki/Q189082', 'display_name': 'Cell culture', 'level': 2, 'score': 0.49005187}, {'id': 'https://openalex.org/C1491633281', 'wikidata': 'https://www.wikidata.org/wiki/Q7868', 'display_name': 'Cell', 'level': 2, 'score': 0.45198572}, {'id': 'https://openalex.org/C163864487', 'wikidata': 'https://www.wikidata.org/wiki/Q6901461', 'display_name': 'Monoclonal', 'level': 4, 'score': 0.42743826}, {'id': 'https://openalex.org/C190062978', 'wikidata': 'https://www.wikidata.org/wiki/Q79899', 'display_name': 'Cytoplasm', 'level': 2, 'score': 0.41401035}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.39484203}, {'id': 'https://openalex.org/C114851261', 'wikidata': 'https://www.wikidata.org/wiki/Q12147416', 'display_name': 'Drug resistance', 'level': 2, 'score': 0.38590634}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.36459616}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.30444282}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.27965233}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.15285301}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.10681307}], 'mesh': [{'descriptor_ui': 'D000911', 'descriptor_name': 'Antibodies, Monoclonal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D006023', 'descriptor_name': 'Glycoproteins', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': True}, {'descriptor_ui': 'D020168', 'descriptor_name': 'ATP Binding Cassette Transporter, Subfamily B, Member 1', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002460', 'descriptor_name': 'Cell Line', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006224', 'descriptor_name': 'Cricetinae', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003412', 'descriptor_name': 'Cricetulus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004351', 'descriptor_name': 'Drug Resistance', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000939', 'descriptor_name': 'Epitopes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000939', 'descriptor_name': 'Epitopes', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005434', 'descriptor_name': 'Flow Cytometry', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005455', 'descriptor_name': 'Fluorescent Antibody Technique', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006023', 'descriptor_name': 'Glycoproteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006023', 'descriptor_name': 'Glycoproteins', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008647', 'descriptor_name': 'Mesocricetus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010053', 'descriptor_name': 'Ovary', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013045', 'descriptor_name': 'Species Specificity', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1038/316820a0', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S137773608', 'display_name': 'Nature', 'issn_l': '0028-0836', 'issn': ['0028-0836', '1476-4687'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319908', 'host_organization_name': 'Nature Portfolio', 'host_organization_lineage': ['https://openalex.org/P4310319908', 'https://openalex.org/P4310319965'], 'host_organization_lineage_names': ['Nature Portfolio', 'Springer Nature'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/2412130', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.83}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 33, 'referenced_works': ['https://openalex.org/W1595352454', 'https://openalex.org/W1669789583', 'https://openalex.org/W175263069', 'https://openalex.org/W1775749144', 'https://openalex.org/W1893651774', 'https://openalex.org/W1900543109', 'https://openalex.org/W1974869964', 'https://openalex.org/W1977461031', 'https://openalex.org/W1977521575', 'https://openalex.org/W1979103854', 'https://openalex.org/W1980362225', 'https://openalex.org/W1984516227', 'https://openalex.org/W1986676191', 'https://openalex.org/W1997241897', 'https://openalex.org/W2012306261', 'https://openalex.org/W2028458233', 'https://openalex.org/W2028533496', 'https://openalex.org/W2034031399', 'https://openalex.org/W2049772927', 'https://openalex.org/W2050783261', 'https://openalex.org/W2051203480', 'https://openalex.org/W2065275202', 'https://openalex.org/W2067570700', 'https://openalex.org/W2073879684', 'https://openalex.org/W2101108802', 'https://openalex.org/W2102131116', 'https://openalex.org/W2111598014', 'https://openalex.org/W2133761830', 'https://openalex.org/W2136701955', 'https://openalex.org/W2140353655', 'https://openalex.org/W2264155967', 'https://openalex.org/W4238917827', 'https://openalex.org/W581386893'], 'related_works': ['https://openalex.org/W4226166860', 'https://openalex.org/W2950442272', 'https://openalex.org/W2497337421', 'https://openalex.org/W2382225335', 'https://openalex.org/W2091807474', 'https://openalex.org/W2074950338', 'https://openalex.org/W2031866272', 'https://openalex.org/W2016114543', 'https://openalex.org/W1999906254', 'https://openalex.org/W1483266284'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2007931369', 'counts_by_year': [{'year': 2024, 'cited_by_count': 5}, {'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 4}, {'year': 2021, 'cited_by_count': 5}, {'year': 2020, 'cited_by_count': 3}, {'year': 2019, 'cited_by_count': 6}, {'year': 2018, 'cited_by_count': 10}, {'year': 2017, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 4}, {'year': 2015, 'cited_by_count': 4}, {'year': 2014, 'cited_by_count': 8}, {'year': 2013, 'cited_by_count': 6}, {'year': 2012, 'cited_by_count': 11}], 'updated_date': '2024-09-18T10:01:19.994317', 'created_date': '2016-06-24'}