Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2006845602', 'doi': 'https://doi.org/10.3390/md10030639', 'title': 'Identification and Characterization of an Anti-Fibrotic Benzopyran Compound Isolated from Mangrove-Derived Streptomyces xiamenensis', 'display_name': 'Identification and Characterization of an Anti-Fibrotic Benzopyran Compound Isolated from Mangrove-Derived Streptomyces xiamenensis', 'publication_year': 2012, 'publication_date': '2012-03-15', 'ids': {'openalex': 'https://openalex.org/W2006845602', 'doi': 'https://doi.org/10.3390/md10030639', 'mag': '2006845602', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/22611360', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/3347021'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3390/md10030639', 'pdf_url': 'https://www.mdpi.com/1660-3397/10/3/639/pdf?version=1424781438', 'source': {'id': 'https://openalex.org/S146563757', 'display_name': 'Marine Drugs', 'issn_l': '1660-3397', 'issn': ['1660-3397'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310310987', 'host_organization_name': 'Multidisciplinary Digital Publishing Institute', 'host_organization_lineage': ['https://openalex.org/P4310310987'], 'host_organization_lineage_names': ['Multidisciplinary Digital Publishing Institute'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'doaj', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://www.mdpi.com/1660-3397/10/3/639/pdf?version=1424781438', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5083207380', 'display_name': 'Min‐Juan Xu', 'orcid': 'https://orcid.org/0000-0003-1768-208X'}, 'institutions': [{'id': 'https://openalex.org/I183067930', 'display_name': 'Shanghai Jiao Tong University', 'ror': 'https://ror.org/0220qvk04', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I183067930']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Min-Juan Xu', 'raw_affiliation_strings': ['Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University, Key Laboratory of Systems Biomedicine, Shanghai 200240, China'], 'affiliations': [{'raw_affiliation_string': 'Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University, Key Laboratory of Systems Biomedicine, Shanghai 200240, China', 'institution_ids': ['https://openalex.org/I183067930']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100728210', 'display_name': 'Xiaojin Liu', 'orcid': 'https://orcid.org/0000-0002-5649-2716'}, 'institutions': [{'id': 'https://openalex.org/I4210144482', 'display_name': "Shanghai Sixth People's Hospital", 'ror': 'https://ror.org/049zrh188', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210144482']}, {'id': 'https://openalex.org/I4210138900', 'display_name': 'State Key Laboratory of Oncogene and Related Genes', 'ror': 'https://ror.org/03xt1x768', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210138900']}, {'id': 'https://openalex.org/I183067930', 'display_name': 'Shanghai Jiao Tong University', 'ror': 'https://ror.org/0220qvk04', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I183067930']}, {'id': 'https://openalex.org/I4210110011', 'display_name': 'Shanghai Cancer Institute', 'ror': 'https://ror.org/01ty4bg86', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210110011']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Xiao-Jin Liu', 'raw_affiliation_strings': ["Department of Plastic Surgery, Shanghai Jiaotong University Affiliated Sixth People's Hospital, Shanghai 200233, China", 'State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200240, China'], 'affiliations': [{'raw_affiliation_string': "Department of Plastic Surgery, Shanghai Jiaotong University Affiliated Sixth People's Hospital, Shanghai 200233, China", 'institution_ids': ['https://openalex.org/I4210144482']}, {'raw_affiliation_string': 'State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200240, China', 'institution_ids': ['https://openalex.org/I4210138900', 'https://openalex.org/I183067930', 'https://openalex.org/I4210110011']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5079289838', 'display_name': 'Yi‐Lei Zhao', 'orcid': 'https://orcid.org/0000-0003-4687-7847'}, 'institutions': [{'id': 'https://openalex.org/I183067930', 'display_name': 'Shanghai Jiao Tong University', 'ror': 'https://ror.org/0220qvk04', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I183067930']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yi-Lei Zhao', 'raw_affiliation_strings': ['State Key Laboratory of Microbial Metabolism and School of Life Science & Biotechnology, Shanghai JiaoTong University, Shanghai 200240, China'], 'affiliations': [{'raw_affiliation_string': 'State Key Laboratory of Microbial Metabolism and School of Life Science & Biotechnology, Shanghai JiaoTong University, Shanghai 200240, China', 'institution_ids': ['https://openalex.org/I183067930']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100407506', 'display_name': 'Dong Liu', 'orcid': 'https://orcid.org/0000-0003-0451-5979'}, 'institutions': [{'id': 'https://openalex.org/I20231570', 'display_name': 'Peking University', 'ror': 'https://ror.org/02v51f717', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I20231570']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Dong Liu', 'raw_affiliation_strings': ['State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China'], 'affiliations': [{'raw_affiliation_string': 'State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China', 'institution_ids': ['https://openalex.org/I20231570']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5056495554', 'display_name': 'Zhen-Hao Xu', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I183067930', 'display_name': 'Shanghai Jiao Tong University', 'ror': 'https://ror.org/0220qvk04', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I183067930']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Zhen-Hao Xu', 'raw_affiliation_strings': ['State Key Laboratory of Microbial Metabolism and School of Life Science & Biotechnology, Shanghai JiaoTong University, Shanghai 200240, China'], 'affiliations': [{'raw_affiliation_string': 'State Key Laboratory of Microbial Metabolism and School of Life Science & Biotechnology, Shanghai JiaoTong University, Shanghai 200240, China', 'institution_ids': ['https://openalex.org/I183067930']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5056055509', 'display_name': 'Xiao-Meng Lang', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I20231570', 'display_name': 'Peking University', 'ror': 'https://ror.org/02v51f717', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I20231570']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Xiao-Meng Lang', 'raw_affiliation_strings': ['State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China'], 'affiliations': [{'raw_affiliation_string': 'State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China', 'institution_ids': ['https://openalex.org/I20231570']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5061224833', 'display_name': 'Ping Ao', 'orcid': 'https://orcid.org/0000-0001-7109-628X'}, 'institutions': [{'id': 'https://openalex.org/I183067930', 'display_name': 'Shanghai Jiao Tong University', 'ror': 'https://ror.org/0220qvk04', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I183067930']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Ping Ao', 'raw_affiliation_strings': ['Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University, Key Laboratory of Systems Biomedicine, Shanghai 200240, China'], 'affiliations': [{'raw_affiliation_string': 'Shanghai Center for Systems Biomedicine, Shanghai Jiao Tong University, Key Laboratory of Systems Biomedicine, Shanghai 200240, China', 'institution_ids': ['https://openalex.org/I183067930']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5002070741', 'display_name': 'Wenhan Lin', 'orcid': 'https://orcid.org/0000-0002-4978-4083'}, 'institutions': [{'id': 'https://openalex.org/I20231570', 'display_name': 'Peking University', 'ror': 'https://ror.org/02v51f717', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I20231570']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Wen-Han Lin', 'raw_affiliation_strings': ['State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China'], 'affiliations': [{'raw_affiliation_string': 'State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China', 'institution_ids': ['https://openalex.org/I20231570']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5036896029', 'display_name': 'Song‐Lin Yang', 'orcid': 'https://orcid.org/0000-0002-3710-8483'}, 'institutions': [{'id': 'https://openalex.org/I4210144482', 'display_name': "Shanghai Sixth People's Hospital", 'ror': 'https://ror.org/049zrh188', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210144482']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Song-Lin Yang', 'raw_affiliation_strings': ["Department of Plastic Surgery, Shanghai Jiaotong University Affiliated Sixth People's Hospital, Shanghai 200233, China"], 'affiliations': [{'raw_affiliation_string': "Department of Plastic Surgery, Shanghai Jiaotong University Affiliated Sixth People's Hospital, Shanghai 200233, China", 'institution_ids': ['https://openalex.org/I4210144482']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100373986', 'display_name': 'Zhigang Zhang', 'orcid': 'https://orcid.org/0000-0001-8965-223X'}, 'institutions': [{'id': 'https://openalex.org/I4210138900', 'display_name': 'State Key Laboratory of Oncogene and Related Genes', 'ror': 'https://ror.org/03xt1x768', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210138900']}, {'id': 'https://openalex.org/I183067930', 'display_name': 'Shanghai Jiao Tong University', 'ror': 'https://ror.org/0220qvk04', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I183067930']}, {'id': 'https://openalex.org/I4210110011', 'display_name': 'Shanghai Cancer Institute', 'ror': 'https://ror.org/01ty4bg86', 'country_code': 'CN', 'type': 'facility', 'lineage': ['https://openalex.org/I4210110011']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Zhi-Gang Zhang', 'raw_affiliation_strings': ['State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200240, China'], 'affiliations': [{'raw_affiliation_string': 'State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200240, China', 'institution_ids': ['https://openalex.org/I4210138900', 'https://openalex.org/I183067930', 'https://openalex.org/I4210110011']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5083207380', 'display_name': 'Min‐Juan Xu', 'orcid': 'https://orcid.org/0000-0003-1768-208X'}, 'institutions': [{'id': 'https://openalex.org/I183067930', 'display_name': 'Shanghai Jiao Tong University', 'ror': 'https://ror.org/0220qvk04', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I183067930']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Jun Xu', 'raw_affiliation_strings': ['State Key Laboratory of Microbial Metabolism and School of Life Science & Biotechnology, Shanghai JiaoTong University, Shanghai 200240, China'], 'affiliations': [{'raw_affiliation_string': 'State Key Laboratory of Microbial Metabolism and School of Life Science & Biotechnology, Shanghai JiaoTong University, Shanghai 200240, China', 'institution_ids': ['https://openalex.org/I183067930']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 5, 'corresponding_author_ids': ['https://openalex.org/A5100373986', 'https://openalex.org/A5083207380'], 'corresponding_institution_ids': ['https://openalex.org/I4210138900', 'https://openalex.org/I183067930', 'https://openalex.org/I4210110011', 'https://openalex.org/I183067930'], 'apc_list': {'value': 2500, 'currency': 'CHF', 'value_usd': 2707, 'provenance': 'doaj'}, 'apc_paid': {'value': 2500, 'currency': 'CHF', 'value_usd': 2707, 'provenance': 'doaj'}, 'fwci': 4.095, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 35, 'citation_normalized_percentile': {'value': 0.99997, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 93, 'max': 94}, 'biblio': {'volume': '10', 'issue': '3', 'first_page': '639', 'last_page': '654'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10870', 'display_name': 'Idiopathic Pulmonary Fibrosis: Diagnosis and Management', 'score': 0.9718, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10870', 'display_name': 'Idiopathic Pulmonary Fibrosis: Diagnosis and Management', 'score': 0.9718, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11340', 'display_name': 'Sponge-Associated Microorganisms and Biotechnological Potential', 'score': 0.925, 'subfield': {'id': 'https://openalex.org/subfields/1305', 'display_name': 'Biotechnology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T13385', 'display_name': 'Emerging Animal Pathogens and Diseases', 'score': 0.9033, 'subfield': {'id': 'https://openalex.org/subfields/3404', 'display_name': 'Small Animals'}, 'field': {'id': 'https://openalex.org/fields/34', 'display_name': 'Veterinary'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/absolute-configuration', 'display_name': 'Absolute configuration', 'score': 0.54430044}, {'id': 'https://openalex.org/keywords/fibrosis', 'display_name': 'Fibrosis', 'score': 0.462133}], 'concepts': [{'id': 'https://openalex.org/C71240020', 'wikidata': 'https://www.wikidata.org/wiki/Q186011', 'display_name': 'Stereochemistry', 'level': 1, 'score': 0.5821742}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.5782984}, {'id': 'https://openalex.org/C25170562', 'wikidata': 'https://www.wikidata.org/wiki/Q2052053', 'display_name': 'Absolute configuration', 'level': 2, 'score': 0.54430044}, {'id': 'https://openalex.org/C2780559512', 'wikidata': 'https://www.wikidata.org/wiki/Q605709', 'display_name': 'Fibrosis', 'level': 2, 'score': 0.4748578}, {'id': 'https://openalex.org/C2777667214', 'wikidata': 'https://www.wikidata.org/wiki/Q70702', 'display_name': 'Alkaloid', 'level': 2, 'score': 0.4707979}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.33281276}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.19817644}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.13374388}], 'mesh': [{'descriptor_ui': 'D001578', 'descriptor_name': 'Benzopyrans', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D001578', 'descriptor_name': 'Benzopyrans', 'qualifier_ui': 'Q000302', 'qualifier_name': 'isolation & purification', 'is_major_topic': True}, {'descriptor_ui': 'D005355', 'descriptor_name': 'Fibrosis', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D019015', 'descriptor_name': 'Geologic Sediments', 'qualifier_ui': 'Q000382', 'qualifier_name': 'microbiology', 'is_major_topic': True}, {'descriptor_ui': 'D013302', 'descriptor_name': 'Streptomyces', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D014197', 'descriptor_name': 'Trees', 'qualifier_ui': 'Q000382', 'qualifier_name': 'microbiology', 'is_major_topic': True}, {'descriptor_ui': 'D001578', 'descriptor_name': 'Benzopyrans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002448', 'descriptor_name': 'Cell Adhesion', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D002448', 'descriptor_name': 'Cell Adhesion', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002460', 'descriptor_name': 'Cell Line', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D045744', 'descriptor_name': 'Cell Line, Tumor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D049109', 'descriptor_name': 'Cell Proliferation', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D049109', 'descriptor_name': 'Cell Proliferation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002851', 'descriptor_name': 'Chromatography, High Pressure Liquid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003094', 'descriptor_name': 'Collagen', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003094', 'descriptor_name': 'Collagen', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D005347', 'descriptor_name': 'Fibroblasts', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D005347', 'descriptor_name': 'Fibroblasts', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005355', 'descriptor_name': 'Fibrosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019015', 'descriptor_name': 'Geologic Sediments', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006868', 'descriptor_name': 'Hydrolysis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007202', 'descriptor_name': 'Indicators and Reagents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009682', 'descriptor_name': 'Magnetic Resonance Spectroscopy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008968', 'descriptor_name': 'Molecular Conformation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013302', 'descriptor_name': 'Streptomyces', 'qualifier_ui': 'Q000254', 'qualifier_name': 'growth & development', 'is_major_topic': False}, {'descriptor_ui': 'D013302', 'descriptor_name': 'Streptomyces', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014197', 'descriptor_name': 'Trees', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 5, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.3390/md10030639', 'pdf_url': 'https://www.mdpi.com/1660-3397/10/3/639/pdf?version=1424781438', 'source': {'id': 'https://openalex.org/S146563757', 'display_name': 'Marine Drugs', 'issn_l': '1660-3397', 'issn': ['1660-3397'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310310987', 'host_organization_name': 'Multidisciplinary Digital Publishing Institute', 'host_organization_lineage': ['https://openalex.org/P4310310987'], 'host_organization_lineage_names': ['Multidisciplinary Digital Publishing Institute'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://doaj.org/article/6b043d4e30b14039987db0329eb8cb26', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306401280', 'display_name': 'DOAJ (DOAJ: Directory of Open Access Journals)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc3347021', 'pdf_url': 'https://europepmc.org/articles/pmc3347021?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347021', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/22611360', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3390/md10030639', 'pdf_url': 'https://www.mdpi.com/1660-3397/10/3/639/pdf?version=1424781438', 'source': {'id': 'https://openalex.org/S146563757', 'display_name': 'Marine Drugs', 'issn_l': '1660-3397', 'issn': ['1660-3397'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310310987', 'host_organization_name': 'Multidisciplinary Digital Publishing Institute', 'host_organization_lineage': ['https://openalex.org/P4310310987'], 'host_organization_lineage_names': ['Multidisciplinary Digital Publishing Institute'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.85, 'display_name': 'Life below water', 'id': 'https://metadata.un.org/sdg/14'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 41, 'referenced_works': ['https://openalex.org/W1583584534', 'https://openalex.org/W1799062390', 'https://openalex.org/W1843040414', 'https://openalex.org/W1926629106', 'https://openalex.org/W1965454525', 'https://openalex.org/W1974005261', 'https://openalex.org/W1974059324', 'https://openalex.org/W1974209145', 'https://openalex.org/W1976141939', 'https://openalex.org/W1980325398', 'https://openalex.org/W1989412685', 'https://openalex.org/W1989963286', 'https://openalex.org/W1992686988', 'https://openalex.org/W1993220177', 'https://openalex.org/W1996361260', 'https://openalex.org/W2008683618', 'https://openalex.org/W2011215428', 'https://openalex.org/W2017541188', 'https://openalex.org/W2021983950', 'https://openalex.org/W2027756860', 'https://openalex.org/W2032639324', 'https://openalex.org/W2044601830', 'https://openalex.org/W2047704960', 'https://openalex.org/W2050742799', 'https://openalex.org/W2073975963', 'https://openalex.org/W2085293124', 'https://openalex.org/W2085336624', 'https://openalex.org/W2089621156', 'https://openalex.org/W2100299975', 'https://openalex.org/W2121990305', 'https://openalex.org/W2123222325', 'https://openalex.org/W2123694231', 'https://openalex.org/W2130454566', 'https://openalex.org/W2146455279', 'https://openalex.org/W2146611064', 'https://openalex.org/W2150072764', 'https://openalex.org/W2161423477', 'https://openalex.org/W2950464663', 'https://openalex.org/W2950659087', 'https://openalex.org/W4242171500', 'https://openalex.org/W4242410317'], 'related_works': ['https://openalex.org/W4382515131', 'https://openalex.org/W2952675974', 'https://openalex.org/W2164492639', 'https://openalex.org/W2067150518', 'https://openalex.org/W2062968969', 'https://openalex.org/W2062307007', 'https://openalex.org/W2057992341', 'https://openalex.org/W2057319081', 'https://openalex.org/W2011625358', 'https://openalex.org/W1971138718'], 'abstract_inverted_index': {'An': [0], 'anti-fibrotic': [1], 'compound': [2, 56], 'produced': [3], 'by': [4, 37], 'Streptomycesn': [5], 'xiamenensis,': [6], 'found': [7], 'in': [8, 88, 119], 'mangrove': [9], 'sediments,': [10], 'was': [11, 23, 35], 'investigated': [12], 'for': [13], 'possible': [14], 'therapeutic': [15, 128], 'effects': [16, 109], 'against': [17, 130], 'fibrosis.': [18, 131], 'The': [19], 'compound,': [20], "N-[[3,4-dihydro-3S-hydroxy-2S-methyl-2-(4'R-methyl-3'S-pentenyl)-2H-1-benzopyran-6-yl]carbonyl]-threonine": [21], '(1),': [22], 'isolated': [24], 'from': [25], 'crude': [26], 'extracts': [27], 'and': [28, 46, 80], 'its': [29], 'structure,': [30], 'including': [31], 'the': [32, 58, 82], 'absolute': [33], 'configuration': [34], 'determined': [36], 'extensive': [38], 'spectroscopic': [39], 'data': [40, 95], 'analyses,': [41], "Mosher's": [42], 'method,': [43], "Marfey's": [44], 'reagent': [45], 'quantum': [47], 'mechanical': [48], 'calculations.': [49], 'In': [50], 'terms': [51], 'of': [52, 60, 67, 77, 85], 'biological': [53, 108], 'effects,': [54], 'this': [55, 123], 'inhibits': [57], 'proliferation': [59], 'human': [61, 68], 'lung': [62, 111], 'fibroblasts': [63], '(WI26),': [64], 'blocks': [65], 'adhesion': [66], 'acute': [69], 'monocytic': [70], 'leukemia': [71], 'cells': [72, 87], '(THP-1)': [73], 'to': [74], 'a': [75, 101], 'monolayer': [76], 'WI26': [78, 86], 'cells,': [79], 'reduces': [81], 'contractile': [83], 'capacity': [84], 'three-dimensional': [89], 'free-floating': [90], 'collagen': [91], 'gels.': [92], 'Altogether,': [93], 'these': [94], 'indicate': [96], 'that': [97, 115, 122], 'we': [98], 'have': [99, 127], 'identified': [100], 'bioactive': [102], 'alkaloid': [103], '(1)': [104], 'with': [105], 'multiple': [106], 'inhibitory': [107], 'on': [110], 'excessive': [112], 'fibrotic': [113], 'characteristics,': [114], 'are': [116], 'likely': [117], 'involved': [118], 'fibrosis,': [120], 'suggesting': [121], 'molecule': [124], 'might': [125], 'indeed': [126], 'potential': [129]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2006845602', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 3}, {'year': 2019, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 3}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 4}, {'year': 2015, 'cited_by_count': 4}, {'year': 2014, 'cited_by_count': 4}, {'year': 2013, 'cited_by_count': 6}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-08-14T05:19:05.419108', 'created_date': '2016-06-24'}