Title: Keramaphidin B, a novel pentacyclic alkaloid from a marine sponge Amphimedon sp. : A plausible biogenetic precursor of manzamine alkaloids
Abstract: Keramaphidin B (1), a novel cytotoxic alkaloid possessing a 1,4-etheno-2,7-decahydronaphthylidine core with two macrocyclic rings has been isolated from an Okinawan marine sponge Amphimedon sp., and the structure was elucidated by extensive 2D NMR investigation as well as a single crystal X-ray analysis. Keramaphidin B (1) might be a plausible biogenetic precursor of manzamine alkaloids and a very important key compound to clarify the biogenetic path.
Publication Year: 1994
Publication Date: 1994-06-01
Language: en
Type: article
Indexed In: ['crossref']
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Cited By Count: 82
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