Publication Information

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'https://openalex.org/W2014959408', 'https://openalex.org/W2011262391', 'https://openalex.org/W1818313483', 'https://openalex.org/W1602103287', 'https://openalex.org/W1587932799', 'https://openalex.org/W1528368632'], 'abstract_inverted_index': {'The': [0, 159, 1307, 1417, 1445, 1457, 2249, 3639, 3710], 'p53': [1, 36, 50, 57, 96, 106, 160, 195, 209, 216, 255, 265, 350, 423, 449, 571, 784, 946, 1151, 1265, 1277, 1291, 1321, 1330, 1340, 1346, 1447, 1487, 1489, 1531, 1547, 1709, 1757, 1764, 1781, 1921, 2484, 2520, 2580, 2654, 2745, 2875, 2880, 2900, 2996, 3088, 3114, 3357, 3388, 3461, 3479, 3556, 3773, 3921, 3967, 4098, 4141], 'tumor': [2, 161, 351], 'suppressor': [3, 162, 352], 'protein': [4, 75, 163, 234, 325, 331, 337, 353, 581, 704, 1126, 2097, 2167, 2881, 3102, 3233, 3457, 3517, 3666], 'preserves': [5, 164], 'genome': [6, 165], 'integrity': [7, 166], 'by': [8, 83, 114, 119, 167, 242, 273, 278, 578, 1130, 1314, 1327, 1442, 1454, 1498, 1791, 2051, 2094, 2128, 2165, 2175, 2500, 2780, 2865, 2890, 3023, 3099, 3161, 3585, 3668, 3688, 3701, 3937, 4061], 'regulating': [9, 168, 783, 3920], 'growth': [10, 169], 'arrest': [11, 170, 3369], 'and': [12, 34, 41, 101, 107, 116, 127, 171, 193, 200, 260, 266, 275, 286, 362, 442, 568, 691, 799, 832, 879, 897, 914, 983, 1035, 1160, 1323, 1336, 1430, 1432, 1512, 1519, 1687, 1704, 1712, 1767, 1808, 1818, 1823, 1839, 1902, 1928, 1959, 1984, 2070, 2076, 2081, 2088, 2157, 2301, 2388, 2442, 2446, 2448, 2451, 2506, 2525, 2540, 2609, 2615, 2629, 2647, 2749, 2759, 2777, 2805, 2832, 2898, 3091, 3104, 3112, 3130, 3141, 3231, 3266, 3375, 3386, 3389, 3564, 3574, 3578, 3628, 3659, 3717, 3765, 3824, 3942, 4017, 4046, 4101, 4107, 4151, 4168, 4172, 4175], 'apoptosis': [13, 152, 172, 311, 3155], 'in': [14, 30, 65, 139, 147, 155, 173, 189, 224, 298, 306, 314, 366, 383, 782, 860, 881, 906, 926, 985, 1332, 1449, 1467, 1721, 1761, 1773, 1788, 1843, 1849, 1908, 1925, 1970, 2024, 2063, 2104, 2267, 2367, 2370, 2412, 2426, 2436, 2457, 2476, 2485, 2493, 2504, 2519, 2547, 2559, 2598, 2736, 2757, 2795, 2822, 2855, 2927, 2994, 3073, 3093, 3156, 3370, 3439, 3445, 3483, 3528, 3569, 3587, 3645, 3679, 3741, 3886, 3965, 4110, 4149], 'response': [15, 20, 66, 174, 179, 225, 345, 2105, 2120, 2371, 2494, 2503, 2599, 2636, 2926, 3094, 3157, 3446, 3484, 3529, 3570, 3588, 3646, 3680], 'to': [16, 21, 67, 175, 180, 226, 346, 574, 628, 1141, 1260, 1298, 1440, 1460, 1504, 1672, 1692, 1784, 1830, 1861, 1870, 1944, 2068, 2106, 2121, 2162, 2179, 2372, 2431, 2495, 2510, 2544, 2563, 2591, 2600, 2637, 2753, 2863, 2910, 2988, 3031, 3041, 3056, 3076, 3095, 3148, 3158, 3167, 3344, 3352, 3363, 3382, 3447, 3485, 3521, 3530, 3539, 3571, 3589, 3633, 3647, 3681, 3685, 3724, 3735, 3875, 3899, 3944, 4009, 4055, 4073, 4089, 4104], 'DNA': [17, 110, 176, 269, 347, 434, 1455, 2496, 2641, 2656, 3448, 3576], 'damage.': [18, 177], 'In': [19, 178, 344, 1120, 1946, 1968, 2119, 2513, 2764, 2793, 2986, 3033, 3350, 3623], 'ionizing': [22, 181, 334], 'radiation': [23, 182, 335, 2837], '(IR),': [24, 183], 'ATM,': [25, 184, 1536, 2394], 'the': [26, 73, 133, 148, 185, 232, 292, 307, 349, 359, 365, 367, 455, 579, 702, 777, 808, 849, 917, 948, 972, 1136, 1142, 1289, 1337, 1345, 1389, 1394, 1433, 1474, 1477, 1482, 1499, 1513, 1674, 1727, 1910, 2129, 2263, 2274, 2423, 2483, 2502, 2523, 2560, 2578, 2621, 2741, 2823, 2873, 2893, 2919, 2995, 3002, 3054, 3059, 3066, 3079, 3100, 3123, 3136, 3152, 3469, 3674, 3695, 3730, 3915, 3926, 3952, 3962, 3996, 3999, 4062, 4084, 4094, 4159, 4166, 4179], 'gene': [27, 186, 3476], 'product': [28, 187, 3470], 'mutated': [29, 188, 322], 'ataxia': [31, 190, 318, 320], 'telangiectasia,': [32, 191], 'stabilizes': [33, 192], 'activates': [35, 194], 'through': [37, 196, 699, 1864, 2661, 3465, 4143], 'phosphorylation': [38, 48, 78, 120, 138, 197, 207, 237, 279, 297, 450, 577, 696, 1678, 1801, 1810, 1844, 1856, 1903, 1922, 1950, 1973, 2057, 2071, 2114, 2269, 2366, 2384, 2404, 2465, 2470, 2521, 2535, 2581, 2597, 2662, 2845, 2859, 3062, 3086, 3127, 3480, 3541, 3554, 3590, 3649, 3656, 3714, 3870, 3888, 3895, 3936, 4043, 4050, 4064, 4144], 'of': [39, 49, 136, 150, 198, 208, 295, 309, 358, 372, 459, 570, 697, 701, 941, 962, 1135, 1309, 1541, 1551, 1677, 1684, 1786, 1799, 1815, 1827, 1866, 1904, 1919, 2115, 2177, 2265, 2270, 2276, 2280, 2380, 2398, 2422, 2440, 2466, 2490, 2605, 2613, 2625, 2652, 2744, 2825, 2868, 2992, 3011, 3061, 3068, 3078, 3087, 3128, 3144, 3154, 3163, 3236, 3336, 3342, 3356, 3360, 3443, 3454, 3467, 3471, 3542, 3555, 3591, 3650, 3655, 3663, 3699, 3713, 3732, 3738, 3826, 3871, 3893, 3896, 3930, 3935, 3998, 4044, 4051, 4065, 4081, 4086, 4096, 4140], 'Ser15': [40, 199, 1975, 2116, 2387, 3055, 3090, 3706, 3872, 3897, 4066], '(indirectly)': [42, 201], 'Ser20.': [43, 202, 2118], 'Here': [44, 203], 'we': [45, 204, 1537, 2272, 2646, 2738, 2851], 'show': [46, 205, 3120], 'that': [47, 143, 206, 302, 429, 447, 825, 842, 1275, 1770, 1772, 1787, 1938, 2086, 2251, 2377, 2534, 2555, 2650, 3025, 3085, 3105, 3126, 3438, 3459, 3477, 3549, 3562, 3580, 3644, 3676, 3697, 3763, 3869, 3914, 4006, 4067, 4078], 'on': [51, 63, 72, 210, 222, 231, 356, 1535, 2364, 2393, 2403, 2593, 3048, 3065, 3135, 3729], 'Ser46,': [52, 211, 1268, 1824, 1957, 2271, 2389, 2467, 2630, 3238, 3463], 'a': [53, 85, 92, 212, 244, 251, 420, 819, 836, 882, 893, 902, 932, 938, 959, 1539, 1714, 1992, 2303, 2634, 2923, 3116, 3472, 3534, 3634, 3739, 3761, 3883, 4057], 'residue': [54, 213], 'important': [55, 214, 453, 2848, 3109, 3150, 3918, 4011, 4069], 'for': [56, 215, 454, 695, 780, 828, 1150, 1264, 1485, 1517, 2595, 2633, 2849, 3053, 3110, 3122, 3151, 3393, 3553, 3672, 3772, 3919, 4012, 4070, 4158, 4165, 4178], 'apoptotic': [58, 217], 'activity,': [59, 218], 'as': [60, 62, 219, 221, 377, 379, 892, 901, 1041, 1496, 1724, 2027, 2888, 2930, 2999, 3001, 3115, 3671, 3960], 'well': [61, 220, 378, 2786, 3000], 'Ser9,': [64, 126, 223, 285, 1155, 1820, 1953, 2537, 2626, 3028, 4047], 'IR': [68, 154, 227, 313, 575, 1507, 1695, 2255, 2432, 2463, 2564, 2756, 2776, 2813, 2914, 3096, 3364, 3486, 3682], 'also': [69, 228, 692, 1706, 2020, 2060, 2090, 2172, 2433, 3019, 3132, 3547, 3956], 'is': [70, 145, 229, 304, 354, 626, 693, 826, 1557, 1859, 2173, 2488, 2611, 2631, 3097, 3519, 3551, 3683, 4007, 4068], 'dependent': [71, 230, 3134, 3660], 'ATM': [74, 115, 144, 233, 274, 303, 580, 625, 781, 2101, 2266, 2281, 2556, 2594, 2614, 3101, 3137, 3390, 3444, 3550], 'kinase.': [76, 235], 'IR-induced': [77, 236, 1841, 1920, 2383, 2638, 3384], 'at': [79, 99, 121, 238, 258, 280, 380, 786, 911, 937, 958, 971, 992, 1153, 1164, 1267, 1279, 1420, 1436, 1549, 1554, 1679, 1699, 1716, 1804, 1813, 1819, 1833, 1847, 1857, 1951, 1974, 2018, 2058, 2072, 2385, 2405, 2420, 2471, 2536, 2618, 2663, 2747, 2768, 2778, 2788, 2799, 2809, 2903, 3017, 3050, 3089, 3462, 3481, 3557, 3657, 3715, 3889, 3905, 4099], 'Ser46': [80, 137, 239, 296, 1280, 2059, 2089, 2124, 2159, 2253, 2365, 2541, 3040, 3131, 3145, 3482, 3527, 3543, 3943], 'was': [81, 117, 240, 276, 890, 956, 1105, 1116, 1128, 1258, 1312, 1452, 1707, 1759, 1768, 1845, 1923, 1961, 1976, 2021, 2049, 2061, 2074, 2160, 2434, 2474, 2498, 2528, 2542, 2770, 2802, 2828, 2901, 2915, 3006, 3013, 3020, 3146], 'inhibited': [82, 241, 2382], 'wortmannin,': [84, 243, 2277], 'phosphatidylinositol': [86, 245], '3-kinase': [87, 246], 'inhibitor,': [88, 247, 3537], 'but': [89, 248], 'not': [90, 249, 790, 1906, 1935, 1942, 2257, 2417, 2480, 2531, 2839, 2916, 3770, 3947, 4092, 4146], 'PD169316,': [91, 250, 2302, 3533], 'p38': [93, 252, 2130, 2304, 3239, 3523, 3535], 'MAPK': [94, 253, 2131, 3240], 'inhibitor.': [95, 254], 'C-terminal': [97, 256, 1701, 3906, 3949, 3958], 'acetylation': [98, 257, 2651, 2746, 2767, 2798, 2824, 2991, 3010, 3049, 3067, 3904, 3959, 4095, 4142], 'Lys320': [100, 259, 1165, 1703, 2748, 2769, 3012, 3069, 4106], 'Lys382,': [102, 261, 1705, 4108], 'which': [103, 262, 706, 1555, 2171, 2843, 2856, 3337, 3525, 3887, 3894], 'may': [104, 263, 1835, 2091, 2110, 2658, 3582, 3652, 4053, 4145], 'stabilize': [105, 264], 'activate': [108, 267, 3736], 'sequence-specific': [109, 268], 'binding,': [111, 270], 'required': [112, 271, 694, 3392, 3552], 'Ser15phosphorylation': [113, 272], 'enhanced': [118, 277], 'nearby': [122, 281], 'residues': [123, 282, 3631, 3929], 'including': [124, 283, 438], 'Ser6,': [125, 284, 1154, 1805, 1952, 2606, 3027], 'Thr18.': [128, 287], 'These': [129, 288, 1667, 2083, 2550], 'observations,': [130, 289], 'together': [131, 290], 'with': [132, 291, 868, 885, 979, 1324, 1481, 1726, 1987, 1991, 2391, 2454, 2589, 2815, 2872, 2892, 2906, 3760, 3794, 3923, 4014, 4049], 'proposed': [134, 293], 'role': [135, 294, 779], 'mediating': [140, 299, 2268], 'apoptosis,': [141, 300, 437, 3385], 'suggest': [142, 301, 446, 2085, 3437, 3643, 3913], 'involved': [146, 305], 'initiation': [149, 308], 'p53-dependent': [151, 310], 'after': [153, 312, 572, 975, 1139, 1510, 1525, 1682, 1719, 1779, 1794, 1825, 1868, 1966, 1982, 2054, 2066, 2254, 2429, 2655, 2751, 2775, 2791, 2812, 2835, 3340, 3358], 'human': [156, 315, 802, 820, 837, 1290, 1690, 2653, 2928, 3373, 3931, 4087, 4105], 'lymphoblastoid': [157, 316], 'cells.': [158, 317, 2549], 'telangiectasia': [319, 321], 'ATM-related': [323], 'CREB-binding': [324], 'histone': [326, 328], 'acetyltransferase': [327], 'deacetylase': [329, 949], 'homeodomain-interacting': [330, 2166], 'kinase': [332, 338, 582, 2098, 2168, 2250, 3103, 3138, 3458, 3518, 3667, 3675, 3703], '2': [333, 1523, 1777, 2052, 2169, 2375, 2781], 'mitogen-activated': [336], 'mouse': [339, 3966, 4082, 4097], 'double': [340, 2642, 3004, 3449, 3953], 'minute': [341], 'p300/CBP-associated': [342], 'factor': [343], 'damage,': [348, 2639], 'phosphorylated': [355, 1152, 1266, 1278, 1558, 2093, 2127, 2164, 2492, 2617, 3568, 3584, 3635], 'each': [357, 1310, 1450, 1468, 1550, 1680, 1814, 2421, 2884], 'seven': [360], 'serines': [361, 3627], 'one': [363], 'threonine': [364, 1434], 'first': [368, 2739, 3124, 3927], '50': [369, 1004], 'amino': [370, 1421], 'acids': [371, 4004], 'its': [373, 384, 3394, 3702, 3708], 'N-terminal': [374, 2579, 2664, 2844, 2858, 3767, 3891, 3916], 'transactivation': [375], 'domain': [376, 388], 'several': [381, 427, 3890], 'sites': [382, 788, 1553, 1817, 2424, 2582, 2665, 2784, 2801, 2827, 2860, 2905, 3907], 'carboxyl': [385], '(C)-terminal': [386], 'tetramerization/regulatory': [387], '(1.Appella': [389, 583], 'E.': [390, 584, 677, 1054, 1084, 1182, 1212, 1244, 1572, 1602, 1634, 1654, 1743, 2004, 2143, 2208, 2695, 2944, 2972, 3217, 3252, 3294, 3604, 3813, 3977, 4120], 'Anderson': [391, 585, 641, 1055, 1081, 1183, 1209, 1241, 1573, 1599, 1631, 2140, 2692, 2941, 2969, 3214, 3249, 3605, 3810, 3974, 4117], 'C.W.': [392, 586, 642, 1056, 1082, 1184, 1210, 1242, 1574, 1600, 1632, 2141, 2693, 2942, 2970, 3215, 3250, 3606, 3811, 3975, 4118], 'Eur.': [393, 587], 'J.': [394, 506, 588, 742, 767, 1057, 1085, 1185, 1213, 1575, 1603, 2148, 2671, 2716, 2945, 2977, 3222, 3257, 3397, 3607, 3750, 3833, 3852, 3973, 3981, 4028, 4173], 'Biochem.': [395, 589], '2001;': [396, 411, 493, 590, 605, 617, 2569, 3428, 3503], '268:': [397, 591], '2764-2772Crossref': [398, 592], 'PubMed': [399, 414, 496, 510, 525, 561, 593, 608, 620, 659, 686, 728, 755, 771, 1068, 1096, 1196, 1224, 1250, 1364, 1383, 1412, 1586, 1614, 1640, 1662, 1751, 1897, 2012, 2043, 2152, 2217, 2244, 2359, 2572, 2675, 2701, 2727, 2956, 2981, 3201, 3226, 3261, 3303, 3330, 3411, 3431, 3511, 3618, 3754, 3787, 3819, 3837, 3863, 3985, 4037, 4133], 'Scopus': [400, 415, 497, 511, 526, 562, 594, 609, 621, 660, 687, 729, 756, 772, 1069, 1097, 1197, 1225, 1251, 1365, 1384, 1413, 1587, 1615, 1641, 1663, 1752, 1898, 2013, 2153, 2218, 2245, 2360, 2573, 2676, 2702, 2728, 2957, 2982, 3202, 3227, 3262, 3304, 3331, 3412, 3432, 3512, 3619, 3755, 3788, 3820, 3838, 3864, 3986, 4038, 4134], '(925)': [401, 595], 'Google': [402, 417, 499, 513, 528, 564, 596, 611, 623, 662, 689, 731, 758, 774, 1071, 1099, 1199, 1227, 1253, 1367, 1386, 1415, 1589, 1617, 1643, 1665, 1754, 1900, 2015, 2044, 2155, 2220, 2247, 2299, 2362, 2575, 2678, 2704, 2730, 2959, 2984, 3204, 3229, 3264, 3306, 3333, 3414, 3434, 3514, 3621, 3757, 3790, 3822, 3840, 3866, 3988, 4040, 4136], 'Scholar,': [403, 500, 514, 529, 597, 612, 663, 732, 759, 1072, 1200, 1228, 1590, 1618, 1644, 2221, 2679, 2705, 2960, 3205, 3307, 3841], '2.Wahl': [404, 598], 'G.M.': [405, 599], 'Carr': [406, 600], 'A.M.': [407, 601], 'Nat.': [408, 602, 2211, 2238, 3297, 3324], 'Cell': [409, 603, 812, 2212, 2239, 3298, 3325], 'Biol.': [410, 492, 604, 1058, 1086, 1186, 1214, 1379, 1576, 1604, 2213, 2240, 2717, 2946, 3299, 3326, 3608, 3783, 3853], '3:': [412, 606], 'E277-E286Crossref': [413, 607], '(328)': [416, 610], 'Scholar).': [418, 565, 624, 775, 1100, 1254, 1416, 1666, 2016, 2248, 2576, 2731, 2985, 3435, 3515, 3622, 3791, 4041, 4137], 'As': [419, 1732], 'transcription': [421, 3117, 3737], 'factor,': [422], 'induces': [424, 3366], 'or': [425, 436, 457, 871, 1162, 1166, 1270, 1283, 1295, 1369, 1488, 1559, 1852, 1912, 2117, 2907, 3029, 3039, 3637, 3707], 'represses': [426], 'genes': [428], 'regulate': [430], 'cell': [431, 823, 840, 918, 1837, 1932, 2460, 3165, 3367, 4170], 'cycle': [432, 3368], 'arrest,': [433], 'repair': [435], 'p21WAF1,MDM2,': [439], 'GADD45,': [440], 'p53R2,': [441], 'p53AIP1.': [443], 'Recent': [444], 'studies': [445, 3083], 'specific': [448, 460, 1149, 1263, 1943], 'events': [451], 'are': [452, 1941, 2847, 3108, 3133, 3338, 3378, 3391, 3719, 3769], 'activation': [456, 569, 700, 1865, 3355, 3442, 3453, 3662], 'repression': [458], 'promoters': [461], '(3.Buschmann': [462], 'T.': [463, 477, 535, 541, 547, 1236, 1626, 2187, 2687, 3175, 3181, 3187, 3273, 3406, 3426, 3492, 3805], 'Potapova': [464], 'O.': [465], 'Bar-Shira': [466], 'A.': [467, 713, 724, 734, 740, 1050, 1178, 1240, 1568, 1630, 2033, 2199, 2225, 2691, 3285, 3311, 3600, 3809, 4129], 'Ivanov': [468], 'V.N.': [469], 'Fuchs': [470], 'S.Y.': [471], 'Henderson': [472], 'S.': [473, 634, 723, 738, 1046, 1076, 1080, 1174, 1204, 1208, 1234, 1353, 1374, 1564, 1594, 1598, 1624, 2135, 2193, 2197, 2210, 2312, 2348, 2685, 2936, 2940, 2964, 3209, 3244, 3279, 3283, 3296, 3403, 3488, 3596, 3803, 3971, 4022, 4116, 4128], 'Fried': [474], 'V.A.': [475], 'Minamoto': [476], 'Alarcon-Vargas': [478], 'D.': [479, 746, 2320, 3399], 'Pincus': [480], 'M.R.': [481], 'Gaarde': [482], 'W.A.': [483, 1883], 'Holbrook': [484], 'N.J.': [485], 'Shiloh': [486, 651], 'Y.': [487, 549, 551, 640, 650, 652, 654, 671, 763, 1044, 1078, 1172, 1206, 1562, 1596, 1650, 1739, 1887, 2000, 2191, 2231, 2938, 3189, 3191, 3277, 3317, 3401, 3496, 3500, 3594, 3979, 4122], 'Ronai': [488], 'Z.': [489], 'Mol.': [490, 1377, 3501, 3781], 'Cell.': [491, 552, 1378, 3192, 3502, 3782], '21:': [494], '2743-2754Crossref': [495], '(255)': [498], '4.Dumaz': [501], 'N.': [502, 2667, 3746, 3829], 'Meek': [503, 2668, 3747, 3830], 'D.W.': [504, 2669, 3748, 3831], 'EMBO': [505, 766, 2147, 2670, 2976, 3221, 3256, 3749, 3832, 3980], '1999;': [507, 725, 768, 1894, 2149, 2672, 2978, 3223, 3258, 3408, 3751, 3784, 3834], '18:': [508, 769, 2150, 2673, 2979, 3224, 3259, 3752, 3835], '7002-7010Crossref': [509, 2674, 3753, 3836], '(391)': [512, 2677, 3756, 3839], '5.Jabbur': [515], 'J.R.': [516], 'Huang': [517], 'P.': [518], 'Zhang': [519], 'W.': [520, 2233, 3319], 'Oncogene.': [521], '2000;': [522, 553, 752, 1060, 1088, 1188, 1216, 1578, 1606, 2040, 2948, 3193, 3610, 3982, 4130], '19:': [523, 3785, 3983], '6203-6208Crossref': [524], '(45)': [527], '6.Oda': [530], 'K.': [531, 537, 545, 673, 675, 1052, 1074, 1180, 1202, 1230, 1570, 1592, 1620, 1652, 1741, 2002, 2139, 2681, 2934, 2968, 3171, 3177, 3185, 3213, 3248, 3602, 3799, 4155], 'Arakawa': [532, 3172, 3489], 'H.': [533, 543, 744, 1402, 2227, 2229, 2235, 3173, 3183, 3313, 3315, 3321, 3490, 3494, 4156], 'Tanaka': [534, 3174, 3491], 'Matsuda': [536, 3176], 'Tanikawa': [538, 3178], 'C.': [539, 648, 765, 1889, 3179, 3969, 4114], 'Mori': [540, 3180], 'Nishimori': [542, 3182], 'Tamai': [544, 672, 3184], 'Tokino': [546, 3186], 'Nakamura': [548, 3188, 3499], 'Taya': [550, 639, 670, 762, 1649, 1738, 1886, 1999, 2230, 3190, 3316, 3495], '102:': [554, 3194], '849-862Abstract': [555, 3195], 'Full': [556, 558, 1063, 1065, 1091, 1093, 1191, 1193, 1219, 1221, 1581, 1583, 1609, 1611, 2722, 2724, 2951, 2953, 3196, 3198, 3506, 3508, 3613, 3615, 3858, 3860], 'Text': [557, 559, 1064, 1066, 1092, 1094, 1192, 1194, 1220, 1222, 1582, 1584, 1610, 1612, 2723, 2725, 2952, 2954, 3197, 3199, 3507, 3509, 3614, 3616, 3859, 3861], 'PDF': [560, 1067, 1095, 1195, 1223, 1585, 1613, 2726, 2955, 3200, 3510, 3617, 3862], '(1031)': [563, 3203], 'Optimal': [566], 'induction': [567, 3153, 3395], 'exposure': [573, 1683, 1826, 1869, 2067, 2176, 2430, 2752, 2909, 3162, 3341, 3359], 'requires': [576, 3704], '7.Abraham': [613], 'R.T.': [614, 1891, 2293, 2566], 'Genes': [615, 1245, 1635, 1657, 1746, 1892, 2007, 2038, 2567, 2696, 3814], 'Dev.': [616, 1246, 1636, 1658, 1747, 1893, 2008, 2039, 2568, 2697, 3815], '15:': [618, 2570], '2177-2196Crossref': [619, 2571], '(1691)': [622, 2574], 'thought': [627, 1860], 'directly': [629], 'phosphorylate': [630], 'Ser15in': [631], 'vivo': [632], '(8.Banin': [633], 'Moyal': [635], 'L.': [636, 644], 'Shieh': [637, 1884], 'S.-Y.': [638, 761, 1885], 'Chessa': [643], 'Smorodinsky': [645], 'N.I.': [646], 'Prives': [647, 764, 1888], 'Reiss': [649], 'Ziv': [653], 'Science.': [655, 682, 751, 1360, 3407, 4033], '1998;': [656, 683, 1247, 1637, 2296, 2698, 2719, 3816, 3855], '281:': [657, 684], '1674-1677Crossref': [658], '(1722)': [661, 688], '9.Canman': [664], 'C.E.': [665, 1648, 1737, 1998], 'Lim': [666], 'D.-S.': [667], 'Cimprich': [668], 'K.A.': [669], 'Sakaguchi': [674, 1051, 1179, 1569, 1651, 1740, 2001, 2138, 2967, 3212, 3247, 3601], 'Appella': [676, 1053, 1083, 1181, 1211, 1243, 1571, 1601, 1633, 1653, 1742, 2003, 2142, 2207, 2694, 2943, 2971, 3216, 3251, 3293, 3603, 3812, 3976, 4119], 'Kastan': [678, 1655, 1744, 2005], 'M.B.': [679, 1656, 1745, 2006], 'Siliciano': [680], 'J.D.': [681, 1646, 1735, 1996], '1677-1679Crossref': [685], 'Scholar)': [690, 1368, 1387, 3265, 3823, 3867], 'Ser20': [698, 2019, 3092], 'Chk2': [703], 'kinase,': [705], 'phosphorylates': [707, 2252, 3460, 3526, 3626, 3677], 'Ser20in': [708], 'vitro': [709, 3624], '(10.Chehab': [710], 'N.H.': [711, 2031], 'Malikzay': [712, 2032], 'Stavridi': [714], 'E.S.': [715], 'Halazonetis': [716, 2036], 'T.D.': [717, 2037], 'Proc.': [718, 4123], 'Natl.': [719, 4124], 'Acad.': [720, 4125], 'Sci.': [721, 4126], 'U.': [722, 4127], '96:': [726], '13777-13782Crossref': [727], '(468)': [730], '11.Hirao': [733], 'Kong': [735], 'Y.-Y.': [736], 'Matsuoka': [737], 'Wakeham': [739], 'Ruland': [741], 'Yoshida': [743], 'Liu': [745], 'Elledge': [747], 'S.J.': [748, 1351], 'Mak': [749], 'T.W.': [750], '287:': [753], '1824-1827Crossref': [754], '(1063)': [757], '12.Shieh': [760], '1815-1823Crossref': [770], '(269)': [773], 'However,': [776, 3372, 3792], 'potential': [778], 'modifications': [785, 1533, 1940, 3107], 'other': [787, 1530, 2438, 2622, 3766], 'has': [789, 2256], 'previously': [791, 2029, 2932, 3560], 'been': [792, 1169, 2258, 3348], 'explored.': [793], 'Epstein-Barr': [794], 'virus': [795], 'immortalized': [796], 'normal': [797, 1685, 1722, 1774, 1789, 1828, 1851, 1911, 1947, 1988, 2414, 2441, 2477, 2524, 2758, 2765, 2816, 2831], '(GM02254)': [798, 1686], 'A-T1': [800], '(GM01526)': [801, 1689], 'lymphoblast': [803], 'cultures': [804, 925, 1478, 1514], 'were': [805, 846, 858, 909, 929, 969, 1039, 1286, 1305, 1342, 1438, 1465, 1479, 1502, 1515, 1669, 1802, 2410, 2785, 2861, 2886, 3070], 'obtained': [806, 847, 2411], 'from': [807, 848, 1107, 1117, 1344, 2883], 'Human': [809], 'Genetic': [810], 'Mutant': [811], 'Repository': [813], '(Camden,': [814], 'NJ).': [815], 'H1299': [816, 1463, 2870], '(ATCC': [817, 834], 'CRL-5803),': [818], 'lung': [821, 838, 1927], 'carcinoma': [822, 839, 1931], 'line': [824, 841, 2461], 'null': [827], 'both': [829, 908, 2386, 2783, 2800, 2904, 3335, 3387, 3572, 4015], 'TP53': [830], 'alleles,': [831], 'A549': [833, 1926, 2368], 'CCL-185),': [835], 'expresses': [843], 'wild-type': [844, 1486, 2899, 2989], 'p53,': [845, 2990, 3876, 3932, 4083], 'American': [850], 'Type': [851], 'Culture': [852], 'Collection': [853], '(Manassas,': [854], 'VA).': [855], 'All': [856], 'cells': [857, 1464, 1775, 2026, 2178, 2369, 2487, 2508, 2871, 3343, 3362, 3377, 4112], 'grown': [859], "Dulbecco's": [861], 'modified': [862, 1548], 'minimal': [863], 'essential': [864, 3771], 'medium': [865], '(Invitrogen)': [866, 1495], 'supplemented': [867], '15%': [869], '(lymphoblasts)': [870], '10%': [872], '(H1299)': [873], 'fetal': [874], 'bovine': [875], 'serum,': [876], '100': [877], 'nmglutamine': [878], 'penicillin/streptomycin': [880], 'humidified': [883], 'atmosphere': [884], '5%': [886], 'CO2.': [887], 'Wortmannin': [888], '(Sigma)': [889], 'prepared': [891, 1320, 1538], '10': [894, 1007, 1022, 1025], 'mm': [895, 904, 990, 996, 999, 1005, 1008, 1012, 1015, 1019], 'stock': [896, 905], 'PD169316': [898, 2399], '(Calbiochem,': [899], 'Inc.)': [900], '1': [903, 1014, 1018, 2428, 2773, 3140], 'Me2SO;': [907], 'stored': [910], '−20': [912], '°C': [913], 'diluted': [915], 'into': [916, 1388, 2586], 'media': [919], 'immediately': [920], 'before': [921, 966, 1776], 'use.': [922], 'Asynchronously': [923], 'growing': [924], '75-cm2': [927], 'flasks': [928], 'irradiated': [930], 'using': [931, 1318, 1491], 'Shepherd': [933], 'Mark': [934], 'I137Cs': [935], 'irradiator': [936], 'dose': [939], 'rate': [940], '3.2': [942], 'Gy/min.': [943], 'To': [944, 1527, 2260, 2732, 2841], 'detect': [945], 'acetylation,': [947, 2850], 'inhibitor': [950, 2279, 2306], 'trichostatin': [951], 'A': [952, 1255, 1915, 2080], '(Wako,': [953], 'Osaka,': [954], 'Japan)': [955], 'added': [957], 'final': [960], 'concentration': [961], '5': [963, 995, 1028], 'μm4': [964], 'h': [965, 1509, 1524, 1718, 1778, 1793, 1981, 2053, 2774, 2790, 2811], 'harvesting.': [967], 'Cultures': [968], 'harvested': [970, 1516], 'indicated': [973, 2874], 'times': [974], 'treatment,': [976], 'washed': [977], 'twice': [978], 'ice-cold': [980, 986], 'phosphate-buffered': [981], 'saline,': [982], 'lysed': [984], 'lysis': [987], 'buffer': [988], '(50': [989], 'Tris-HCl': [991], 'pH': [993], '7.5,': [994], 'EDTA,': [997], '150': [998], 'NaCl,': [1000], '1%': [1001], 'Triton': [1002], 'X-100,': [1003], 'NaF,': [1006], 'sodium': [1009, 1016, 1020], 'pyrophosphate,': [1010], '25': [1011], 'β-glycerolphosphate,': [1013], 'orthovanadate,': [1017], 'molybdate,': [1021], 'μg/ml': [1023, 1026, 1029], 'aprotinin,': [1024], 'leupeptin,': [1027], 'pepstatin,': [1030], '0.5': [1031], 'mmphenylmethylsulfonyl': [1032], 'fluoride).': [1033], 'Immunoprecipitation': [1034], 'Western': [1036, 1122, 1520], 'blot': [1037, 1123, 1521], 'analyses': [1038], 'performed': [1040], 'described': [1042, 1170], '(13.Higashimoto': [1043, 1171, 1561, 3593], 'Saito': [1045, 1075, 1173, 1203, 1233, 1563, 1593, 1623, 2134, 2192, 2684, 2935, 2963, 3208, 3243, 3278, 3595, 3802, 3970, 4115, 4177], 'Tong': [1047, 1175, 1565, 3597], 'X.-H.': [1048, 1176, 1566, 3598], 'Hong': [1049, 1177, 1567, 3599], 'Chem.': [1059, 1087, 1187, 1215, 1577, 1605, 2355, 2718, 2947, 3609, 3854], '275:': [1061, 1089, 1189, 1217, 1579, 1607, 2949, 3611], '23199-23203Abstract': [1062, 1190, 1580, 3612], '(104)': [1070, 1198, 1588, 3620], '14.Sakaguchi': [1073, 1201, 1591], 'Higashimoto': [1077, 1205, 1595, 2190, 2937, 3276], 'Roy': [1079, 1207, 1597, 2939], '9278-9283Abstract': [1090, 1218, 1608, 2950], '(240)': [1098, 1226, 1616, 2958], 'Anti-p53': [1101], 'monoclonal': [1102, 1729], 'antibody': [1103, 1114, 1311, 1730, 2896], 'DO-1': [1104], 'purchased': [1106], 'Santa': [1108], 'Cruz': [1109], 'Biotechnology': [1110], 'Inc.;': [1111], 'anti-p53': [1112], 'polyclonal': [1113, 1147, 1542], 'Ab-7': [1115], 'Calbiochem,': [1118], 'Inc.': [1119], 'all': [1121], 'analyses,': [1124], 'uniform': [1125], 'loading': [1127], 'confirmed': [1129, 1313, 1453], 'Coomassie': [1131], 'Brilliant': [1132], 'Blue': [1133], 'staining': [1134, 2891], 'SDS-polyacrylamide': [1137], 'gels': [1138], 'transfer': [1140], 'polyvinylidene': [1143], 'difluoride': [1144], 'membranes.': [1145], 'Rabbit': [1146], 'antibodies': [1148, 1262, 1274, 1304, 1543, 1668], 'Ser15,': [1156, 1821, 1954, 2538, 2627, 4088], 'Ser20,': [1157, 1822, 1955, 2539, 2628, 3036, 3673, 3939], 'Ser33,': [1158, 1806, 1956, 2607, 3037, 3940], 'Ser37,': [1159, 3038, 3941], 'Thr18': [1161, 1834, 1848, 3030], 'acetylated': [1163, 1560, 2787, 2902], 'Lys382': [1167, 2750, 2779, 2993, 3018], 'have': [1168, 3347], '15.Sakaguchi': [1229, 1619, 2680], 'Herrera': [1231, 1621, 2682, 3800], 'J.E.': [1232, 1622, 2683, 3801], 'Miki': [1235, 1625, 2686, 3804], 'Bustin': [1237, 1627, 2688, 3806], 'M.': [1238, 1628, 2035, 2195, 2206, 2689, 3281, 3292, 3498, 3776, 3807, 4162], 'Vassilev': [1239, 1629, 2690, 3808], '12:': [1248, 1638, 2699, 3817], '2831-2841Crossref': [1249, 1639, 2700, 3818], '(1036)': [1252, 1642, 2703, 3821], 'similar': [1256, 1917, 2455], 'approach': [1257], 'used': [1259, 1671], 'generate': [1261], 'Ser315,': [1269, 1807, 1958, 2608], 'Ser392.': [1271], 'Briefly,': [1272], 'rabbit': [1273], 'recognize': [1276, 1546], '(PAbSer(P)46),': [1281], 'Ser315(PAbSer(P)315),': [1282], 'Ser392': [1284, 1960], '(PAbSer(P)392)': [1285], 'elicited': [1287], 'against': [1288], 'sequences': [1292, 1341], 'Ac-41–51(46P)C,': [1293], 'Ac-310–321(315P)C': [1294], 'Ac-C-385–393(392P)': [1296], 'coupled': [1297, 3793], 'keyhole': [1299], 'limpet': [1300], 'hemocyanin,': [1301], 'respectively.': [1302], 'Phosphorylation-specific': [1303], 'affinity-selected.': [1306], 'specificity': [1308], 'enzyme-linked': [1315], 'immunosorbent': [1316], 'assay': [1317], 'synthetically': [1319], 'peptides': [1322], 'immunoblot': [1325], 'assays': [1326, 3744], 'probing': [1328], 'GST-human': [1329], 'expressed': [1331], 'Escherichia': [1333], 'coli.': [1334], 'Wild-type': [1335], 'L22Q/W23S': [1338, 3003, 3955], 'mutant': [1339, 2853, 3954], 'subcloned': [1343], 'expression': [1347, 1391, 1483, 2876], 'vectors': [1348, 1484, 2877], 'pC53-SN3': [1349], '(16.Baker': [1350], 'Markowitz': [1352], 'Fearon': [1354], 'E.R.': [1355], 'Willson': [1356], 'J.K.': [1357], 'Vogelstein': [1358], 'B.': [1359, 2185, 3271, 4026], '1990;': [1361], '249:': [1362], '912-915Crossref': [1363], '(1613)': [1366], 'pCB6+p53–22/23': [1370, 4160], '(17.Ludwig': [1371], 'R.L.': [1372], 'Bates': [1373], 'Vousden': [1375, 3779, 4157], 'K.H.': [1376, 3780], '1996;': [1380, 4034], '16:': [1381], '4952-4960Crossref': [1382], '(253)': [1385], 'pCAGGS': [1390, 4180], 'plasmid': [1392], 'behind': [1393], 'CAG': [1395], '(cytomegalovirus': [1396], 'enhancer-chicken': [1397], 'β-actin': [1398], 'hybrid)': [1399], 'promoter': [1400], '(18.Niwa': [1401], 'Yamamura': [1403], 'K.-i.': [1404], 'Miyazaki': [1405, 4174], 'J.-i.': [1406], 'Gene': [1407], '(Amst.).': [1408], '1991;': [1409], '108:': [1410], '193-199Crossref': [1411], '(4662)': [1414], 'serine': [1418, 3636, 3723], 'codons': [1419], 'acid': [1422], 'positions': [1423], '6,': [1424], '9,': [1425], '15,': [1426], '20,': [1427], '33,': [1428], '37,': [1429], '46,': [1431], 'codon': [1435], '18,': [1437], 'changed': [1439, 2862, 3026], 'alanine': [1441, 3725], 'site-directed': [1443], 'mutagenesis.': [1444], 'entire': [1446], 'sequence': [1448], 'vector': [1451], 'sequencing.': [1456], 'day': [1458], 'prior': [1459, 2113], 'transfection,': [1461, 1511], '106': [1462], 'seeded': [1466], '10-cm': [1469], 'tissue': [1470], 'culture': [1471], 'plate.': [1472], 'On': [1473], 'following': [1475], 'day,': [1476], 'transfected': [1480], 'mutants': [1490, 3064], 'LipofectAMINE': [1492], 'PLUS': [1493], 'Reagent': [1494], 'recommended': [1497], 'manufacturer.': [1500], 'Cells': [1501], 'exposed': [1503, 2509], '8': [1505, 1693, 2754], 'Gy': [1506, 1694, 2755], '18': [1508, 3928], 'immunoprecipitation': [1518], 'analysis': [1522], 'IR.': [1526, 1831, 1967, 2055, 2373, 2601, 2792, 2911], 'determine': [1528, 2842], 'whether': [1529], 'posttranslational': [1532], 'depend': [1534, 2111], 'panel': [1540], 'that,': [1544], 'respectively,': [1545, 4109], '12': [1552], 'it': [1556], '19.Siliciano': [1645], 'Canman': [1647, 1736, 1997], '1997;': [1659, 1748, 2009, 2356], '11:': [1660, 1749, 2010], '3471-3481Crossref': [1661, 1750, 2011], '(715)': [1664, 1753, 2014], 'then': [1670, 1782], 'examine': [1673], 'time': [1675, 2742], 'course': [1676, 2743], 'site': [1681, 2473, 3063], 'A-T': [1688, 1762, 1853, 1913, 1971, 2025, 2064, 2443, 2459, 2486, 2526, 2548, 2760, 2796, 2833], 'lymphoblasts': [1691, 1790, 1829, 2065, 2415, 2478, 2527, 2761, 2817, 2834], '(Fig.': [1696, 2078, 2762, 2818, 2878, 3544, 3880, 3908], '1).': [1697], 'Acetylation': [1698, 2912, 3016], 'two': [1700, 2437, 2587, 3232, 3630], 'sites,': [1702, 3892], 'examined.': [1708], 'accumulated': [1710], 'rapidly': [1711, 1812], 'reached': [1713], 'maximum': [1715], '4': [1717, 1792, 2789, 2810], 'irradiation': [1720], 'lymphoblasts,': [1723, 1948, 1972, 1989, 2444, 2766, 2797], 'detected': [1725], 'p53-specific': [1728, 2895], 'DO-1.': [1731], 'expected': [1733], '(19.Siliciano': [1734, 1995], 'Scholar),': [1755, 1901, 2045, 2156, 2300, 2363, 3230, 3334, 3758, 3989], 'delayed': [1756, 1978, 2077, 2804], 'accumulation': [1758], 'seen': [1760], 'lymphoblasts.': [1763, 1854, 1914, 1945], 'increased': [1765, 1783, 1811, 1949], 'slowly': [1766], 'less': [1769, 3071], 'half': [1771], 'IR;': [1780], '∼80%': [1785], 'irradiation.': [1795], 'Although': [1796], 'low': [1797, 2619], 'levels': [1798, 2882], 'constitutive': [1800], 'observed': [1803, 1846, 1907, 1924, 1962, 2050, 2475, 2529, 2771, 2829], 'Ser392,': [1809, 2610], 'these': [1816, 1939, 2108, 2826, 3106, 3764, 3990], 'Phosphorylation': [1832, 2017, 2419, 3143], 'be': [1836, 2092, 2126, 2163, 2545, 2584, 2659, 3149, 3522, 3583, 3653, 3686, 3900, 4010, 4147], 'line-dependent,': [1838], 'no': [1840, 2401, 2516], 'increase': [1842], 'either': [1850, 1909, 2406, 3705, 3722], 'Likewise,': [1855], 'Ser37': [1858], 'occur': [1862], 'primarily': [1863, 3365], 'ATR': [1867], 'e.g.': [1871], 'UV': [1872, 2122, 2180, 2511, 2836, 3168, 3345, 3353], 'light': [1873, 2181, 3169], '(20.Tibbetts': [1874], 'R.S.': [1875, 2285, 2334], 'Brumbaugh': [1876], 'K.M.': [1877], 'Williams': [1878], 'J.M.': [1879, 2330], 'Sarkaria': [1880], 'J.N.': [1881, 2283, 2715, 3851], 'Cliby': [1882], 'Abraham': [1890, 2292], '13:': [1895], '152-157Crossref': [1896], '(876)': [1899], 'Ser37was': [1905], 'very': [1916], 'pattern': [1918], 'MCF7': [1929], 'breast': [1930], 'lines': [1933, 3166], '(data': [1934, 2416, 2479, 2530, 2838], 'shown),': [1936, 2532], 'indicating': [1937, 2533], 'within': [1963, 2772], '15': [1964], 'min': [1965], 'contrast,': [1969, 2794, 3034], 'significantly': [1977, 2803, 3021], '(until': [1979], '∼2': [1980], 'IR)': [1983], 'reduced': [1985, 2075, 2806, 3014, 3022], 'compared': [1986, 2814], 'consistent': [1990, 2390, 3759], 'previous': [1993, 2553, 3796], 'report': [1994, 3762], 'largely': [2022], 'abrogated': [2023], 'reported': [2028, 2161, 2931, 3561], '(21.Chehab': [2030], 'Appel': [2034], '14:': [2041], '278-288Crossref': [2042], 'although': [2046], 'some': [2047], 'Ser20phosphorylation': [2048], 'Unexpectedly,': [2056], 'defective': [2062], 'IR,': [2069, 2107, 3648], 'Ser9': [2073, 2087, 3129, 3565, 3581, 3651, 3678, 3700, 3718], '1,': [2079], 'B).': [2082], 'data': [2084, 3640, 3879, 3911], 'an': [2095, 2278, 3455, 3664], 'ATM-activated': [2096], '(or': [2099], 'possibly': [2100, 3464], 'itself);': [2102], 'alternatively,': [2103], 'phosphorylations': [2109, 3768], 'upon': [2112, 3661], 'irradiation,': [2123], 'can': [2125, 2583], '(22.Bulavin': [2132, 3241], 'D.V.': [2133, 2962, 3207, 3242], 'Hollander': [2136, 2965, 3210, 3245], 'M.C.': [2137, 2966, 3211, 3246], 'Fornace': [2144, 2973, 3218, 3253], 'Jr.,': [2145, 2974, 3219, 3254], 'A.J.': [2146, 2340, 2975, 3220, 3255, 4030], '6845-6854Crossref': [2151, 2980, 3225, 3260], '(602)': [2154, 2983, 3228, 3263], 'recently': [2158, 3473], '(HIPK2),': [2170], 'activated': [2174, 3339, 3687], "(23.D'Orazi": [2182, 3268], 'G.': [2183, 2202, 2204, 3269, 3288, 3290, 3420], 'Cecchinelli': [2184, 3270], 'Bruno': [2186, 3272], 'Manni': [2188, 3274], 'I.': [2189, 3275, 4176], 'Gostissa': [2194, 3280], 'Coen': [2196, 3282], 'Marchetti': [2198, 3284], 'Del': [2200, 3286], 'Sal': [2201, 3287], 'Piaggio': [2203, 3289], 'Fanciulli': [2205, 3291], 'Soddu': [2209, 3295], '2002;': [2214, 2241, 3300, 3327], '4:': [2215, 2242, 3301, 3328], '11-19Crossref': [2216, 3302], '(587)': [2219, 3305], '24.Hofmann': [2222, 3308], 'T.G.': [2223, 3309], 'Möller': [2224, 3310], 'Sirma': [2226, 3312], 'Zentgraf': [2228, 3314], 'Dröge': [2232, 3318], 'Will': [2234, 3320], 'Schmitz': [2236, 3322], 'M.L.': [2237, 3323], '1-10Crossref': [2243, 3329], '(510)': [2246, 3332], 'identified.': [2259], 'further': [2261, 3912], 'establish': [2262], 'importance': [2264], 'examined': [2273, 2435, 2740, 2852], 'effect': [2275, 2402, 3047, 3728], '(25.Sarkaria': [2282], 'Tibbetts': [2284], 'Busby': [2286], 'E.C.': [2287], 'Kennedy': [2288], 'A.P.': [2289], 'Hill': [2290], 'D.E.': [2291], 'Cancer': [2294], 'Res.': [2295], '58:': [2297], '4375-4382PubMed': [2298], 'MAPK-specific': [2305], '(26.Gallagher': [2307], 'T.F.': [2308], 'Seibel': [2309], 'G.L.': [2310], 'Kassis': [2311], 'Laydon': [2313], 'J.T.': [2314], 'Blumenthal': [2315], 'M.J.': [2316], 'Lee': [2317, 2319], 'J.C.': [2318, 2322, 3422], 'Boehm': [2321], 'Fier-Thompson': [2323], 'S.M.': [2324], 'Abt': [2325], 'J.W.': [2326], 'Soreson': [2327], 'M.E.': [2328], 'Smietana': [2329], 'Hall': [2331], 'R.F.': [2332], 'Garigipati': [2333], 'Bender': [2335], 'P.E.': [2336], 'Erhard': [2337], 'K.F.': [2338], 'Krog': [2339], 'Hofmann': [2341], 'G.A.': [2342], 'Sheldrake': [2343], 'P.L.': [2344], 'McDonnell': [2345], 'P.C.': [2346], 'Kumar': [2347], 'Young': [2349], 'P.R.': [2350], 'Adams': [2351], 'J.L.': [2352], 'Bioorg.': [2353], 'Med.': [2354], '5:': [2357], '49-64Crossref': [2358], '(224)': [2361], 'Fig.': [2374, 2427], 'shows': [2376], 'increasing': [2378, 2396], 'concentrations': [2379, 2397], 'wortmannin': [2381], 'dependence': [2392, 2592], 'while': [2395, 2468, 3009], 'had': [2400, 3043, 3726], 'site.': [2407], 'Similar': [2408], 'results': [2409, 3797], 'BT': [2413, 2449, 4167], 'shown).': [2418, 2481, 2840], 'shown': [2425, 2499, 2889, 3147], 'pairs': [2439], 'C3ABR': [2445], 'AT24RM,': [2447], '(normal)': [2450], 'L3': [2452, 4169], '(A-T),': [2453], 'results;': [2456], 'neither': [2458], 'did': [2462, 3946, 3961, 4091], 'induce': [2464], 'robust': [2469], 'this': [2472, 2514, 2734], 'That': [2482], 'capable': [2489, 3235], 'being': [2491], 'damage': [2497, 2657, 3159, 3577], 'examining': [2501], 'GM02254': [2505], 'GM01526': [2507], 'light.': [2512], 'case,': [2515], 'significant': [2517], 'difference': [2518], 'between': [2522, 2830], 'unlikely': [2543, 3520], 'masked': [2546], 'findings': [2551], 'fit': [2552], 'observations': [2554], 'acts': [2557], 'specifically': [2558], 'cellular': [2561], 'responses': [2562], '(7.Abraham': [2565], 'Thus,': [2577, 3670, 4042, 4138], 'grouped': [2585], 'categories': [2588], 'respect': [2590], 'rapid': [2596, 2635], 'One': [2602], 'group,': [2603, 2623], 'consisting': [2604, 2624], 'independent': [2612, 3654], 'constitutively': [2616], 'levels;': [2620], 'ATM-dependent': [2632], 'presumably': [2640], 'strand': [2643, 3450], 'breaks.': [2644], 'Previously,': [2645], 'others': [2648, 3827], 'suggested': [2649, 3579], 'mediated': [2660, 3098], '(4.Dumaz': [2666, 3745, 3828], '27.Lambert': [2706, 3842], 'P.F.': [2707, 3843], 'Kashanchi': [2708, 3844], 'F.': [2709, 3845, 4163], 'Radonovich': [2710, 3846], 'M.F.': [2711, 3847], 'Shiekhattar': [2712, 3848], 'R.': [2713, 3849], 'Brady': [2714, 3850], '273:': [2720, 3856], '33048-33053Abstract': [2721, 3857], '(364)': [2729, 3865], 'address': [2733], 'issue': [2735], 'vivo,': [2737], '3A).': [2763], 'h;': [2782], '(by': [2807], '20–40%)': [2808], '3B).': [2819], 'No': [2820], 'differences': [2821], 'site(s)': [2846], 'p53s': [2854], 'individual': [2857], 'Ala': [2864, 3042, 3057, 3945, 4090], 'transient': [2866, 3742], 'transfection': [2867, 2885, 2920, 3743], 'p53-negative': [2869], '3C).': [2879], 'comparable': [2887], 'polyclonal,': [2894], 'Ab-7,': [2897], 'without': [2908, 2913], 'unexpected,': [2917], 'since': [2918, 3532, 3933], 'procedure': [2921], 'elicits': [2922], 'strong': [2924], '"stress-like"': [2925], 'cells,': [2929, 3441], '(14.Sakaguchi': [2933], '22.Bulavin': [2961, 3206], 'contrast': [2987, 3351], 'S15A': [2997], 'mutant,': [2998, 3005], 'virtually': [3007], 'abrogated,': [3008], 'significantly.': [3015], 'mutations': [3024, 3964], 'Ala.': [3032], 'changing': [3035, 3938, 4079], 'little,': [3044], 'if': [3045], 'any,': [3046], 'Lys382.': [3051], 'Except': [3052], 'change,': [3058], 'effects': [3060], 'clear,': [3072], 'part,': [3074], 'due': [3075], 'weakness': [3077], 'Ac-Lys320': [3080], 'signal.': [3081], 'Previous': [3082], 'showed': [3084], 'stabilizing': [3111], 'activating': [3113], 'factor.': [3118], 'We': [3119, 3436, 3546, 3559, 3690, 4075, 4153], 'here,': [3121], 'time,': [3125], '(Figs.': [3139], '4).': [3142, 3909], 'caused': [3160], 'epithelial-derived': [3164], '(6.Oda': [3170], 'kinases': [3234], 'phosphorylating': [3237], 'HIPK2': [3267], 'light,': [3346, 3354], 'described.': [3349], 'epithelial': [3361], 'G1.': [3371], 'lymphoid': [3374, 3440], 'neuronal': [3376], 'much': [3379], 'more': [3380], 'sensitive': [3381], 'p53-dependent,': [3383], '(28.Karlseder': [3396], 'Broccoli': [3398], 'Dai': [3400], 'Hardy': [3402], 'de': [3404], 'Lange': [3405], '283:': [3409], '1321-1325Crossref': [3410], '(920)': [3413], 'Scholar,29.Pettitt': [3415], 'A.R.': [3416], 'Sherrington': [3417], 'P.D.': [3418], 'Stewart': [3419], 'Cawley': [3421], 'Taylor': [3423], 'A.M.R.': [3424], 'Stankovic': [3425], 'Blood.': [3427], '98:': [3429], '814-822Crossref': [3430], '(212)': [3433], 'breaks': [3451], 'mediates': [3452], 'unidentified': [3456], 'recruitment': [3466], 'p53DINP1,': [3468], 'identified': [3474], 'p53-inducible': [3475], 'facilitates': [3478], '(30.Okamura': [3487], 'Nakanishi': [3493], 'Monden': [3497], '8:': [3504], '85-94Abstract': [3505], '(294)': [3513], 'This': [3516], 'MAPK,': [3524], 'UV,': [3531], 'kinase-specific': [3536], 'failed': [3538], 'block': [3540, 4093], '2).': [3545], 'found': [3548], 'Ser9.': [3558], 'Ser6': [3563, 3592, 3658, 3716, 4045], 'became': [3566], 'strongly': [3567], 'IR-': [3573], 'UV-induced': [3575], 'CK1': [3586, 3625], 'threonines': [3629], 'distal': [3632], 'threonine.': [3638], 'presented': [3641], 'here': [3642], 'unknown': [3665], 'ATM.': [3669, 3689], 'likely': [3684, 3993, 4008], 'cannot,': [3691], 'however,': [3692, 4077], 'rule': [3693], 'out': [3694], 'possibility': [3696], 'recognition': [3698], 'phosphorylation.': [3709], 'functional': [3711], 'consequences': [3712], 'unknown.': [3720], 'Changing': [3721], 'little': [3727], 'ability': [3731], 'chimeric': [3733], 'Gal4-p53(1–42)': [3734], 'reporter': [3740], 'activity': [3774], '(31.Ashcroft': [3775], 'Kubbutat': [3777], 'M.H.G.': [3778], '1751-1758Crossref': [3786], '(382)': [3789], 'our': [3795, 3877], '(15.Sakaguchi': [3798], 'those': [3825], 'showing': [3868], 'recruits': [3873], 'CBP/p300': [3874], 'current': [3878], '3C)': [3881], 'supports': [3882], 'cascade': [3884], 'model': [3885], 'appears': [3898], 'most': [3901, 3992], 'important,': [3902], 'promotes': [3903], 'Our': [3910], 'region': [3917, 4002], 'interactions': [3922, 4013], 'HATs': [3924, 4016, 4072], 'includes': [3925], 'abrogation': [3934], 'affect': [3948, 3995], 'acetylation.': [3950], 'While': [3951], 'blocked': [3957], 'equivalent': [3963, 4085, 4103, 4148], '(32.Chao': [3968], 'Kang': [3972], 'Xu': [3978, 4121], '4967-4975Crossref': [3984], '(228)': [3987], 'changes': [3991], 'profoundly': [3994], 'structure': [3997], 'amphipathic': [4000], 'helical': [4001], '(amino': [4003], '17–28)': [4005], 'MDM2': [4018], '(33.Kussie': [4019], 'P.H.': [4020], 'Gorina': [4021], 'Marechal': [4023], 'V.': [4024], 'Elenbaas': [4025], 'Moreau': [4027], 'Levine': [4029], 'Pavletich': [4031], 'N.P.': [4032], '274:': [4035], '948-953Crossref': [4036], '(1845)': [4039], 'along': [4048], 'Thr18,': [4052], 'serve': [4054], 'amplify': [4056], 'primary': [4058], 'signal': [4059], 'initiated': [4060], 'ATM-mediated': [4063], 'recruiting': [4071], 'p53.': [4074], 'note,': [4076], 'Ser18': [4080], 'Lys317': [4100], 'Lys379,': [4102], 'ES': [4111], '(34.Chao': [4113], '97:': [4131], '11936-11941Crossref': [4132], '(149)': [4135], 'regulation': [4139], 'mice': [4150], 'humans.': [4152], 'thank': [4154], 'plasmid,': [4161], 'Lavin': [4164], 'lines,': [4171], 'plasmid.': [4181]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2005236007', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 7}, {'year': 2022, 'cited_by_count': 7}, {'year': 2021, 'cited_by_count': 15}, {'year': 2020, 'cited_by_count': 8}, {'year': 2019, 'cited_by_count': 7}, {'year': 2018, 'cited_by_count': 9}, {'year': 2017, 'cited_by_count': 18}, {'year': 2016, 'cited_by_count': 11}, {'year': 2015, 'cited_by_count': 13}, {'year': 2014, 'cited_by_count': 23}, {'year': 2013, 'cited_by_count': 9}, {'year': 2012, 'cited_by_count': 9}], 'updated_date': '2024-12-17T15:18:17.395013', 'created_date': '2016-06-24'}