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Results for 'Wortmannin'
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Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses Publication Year: 1993
DOI: https://doi.org/10.1042/bj2960297
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Authors:
Alexandre Arcaro
Matthias P. Wymann
Wortmannin, a potent and selective inhibitor of phosphatidylinositol-3-kinase. Publication Year: 1994
DOI: DOI not
available
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Authors:
Garth Powis
Rosanne Bonjouklian
Margareta Berggren
Alfred Gallegos
Robert T. Abraham
Curtis L. Ashendel
Leon H. Zalkow
William F. Matter
Jeffrey A. Dodge
Gerald B. Grindey
Inhibition of histamine secretion by wortmannin through the blockade of phosphatidylinositol 3-kinase in RBL-2H3 cells. Publication Year: 1993
DOI: https://doi.org/10.1016/s0021-9258(19)74466-4
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Authors:
Hiroshi Yano
S. Nakanishi
Koutarou D. Kimura
Nobuo Hanai
Yutaka Saitoh
Yoshinori Fukui
Yoshimune Nonomura
Y Matsuda
Essential role of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes. Studies with a selective inhibitor wortmannin. Publication Year: 1994
DOI: https://doi.org/10.1016/s0021-9258(17)41901-6
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Authors:
Taro Okada
Y. Kawano
Tsuneki Sakakibara
Osamu Hazeki
M Ui
The Phosphatidylinositol 3‐Kinase Inhibitors Wortmannin and LY294002 Inhibit Autophagy in Isolated Rat Hepatocytes Publication Year: 1997
DOI: https://doi.org/10.1111/j.1432-1033.1997.0240a.x
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Authors:
Edward F. C. Blommaart
U. Krause
Jacques P. M. Schellens
Heleen Vreeling‐Sindelárová
Alfred J. Meijer
Structural Determinants of Phosphoinositide 3-Kinase Inhibition by Wortmannin, LY294002, Quercetin, Myricetin, and Staurosporine Publication Year: 2000
DOI: https://doi.org/10.1016/s1097-2765(05)00089-4
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Authors:
Edward H. Walker
Michael E. Pacold
Olga Perišić
Len R. Stephens
Phillip T. Hawkins
Matthias P. Wymann
Roger Williams
Wortmannin, a microbial product inhibitor of myosin light chain kinase. Publication Year: 1992
DOI: https://doi.org/10.1016/s0021-9258(18)45857-7
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Authors:
S. Nakanishi
Shingo Kakita
ISAMI TAKAHASHI
K Kawahara
E. Tsukuda
Tsuneji Sano
Kenneth M. Yamada
Mayumi Yoshida
Hiroshi Kase
Y Matsuda
Wortmannin Inactivates Phosphoinositide 3-Kinase by Covalent Modification of Lys-802, a Residue Involved in the Phosphate Transfer Reaction Publication Year: 1996
DOI: https://doi.org/10.1128/mcb.16.4.1722
Abstract:
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Authors:
Matthias P. Wymann
Ginette Bulgarelli-Leva
Marketa Zvelebil
Luciano Pirola
Bart Vanhaesebroeck
Michael D. Waterfield
George Panayotou
Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin. Publication Year: 1998
DOI: DOI not
available
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Authors:
Jann N. Sarkaria
Randal S. Tibbetts
Ericka C. Busby
Amy P. Kennedy
David E. Hill
Robert T. Abraham
Insulin-stimulated production of nitric oxide is inhibited by wortmannin. Direct measurement in vascular endothelial cells. Publication Year: 1996
DOI: https://doi.org/10.1172/jci118871
Abstract:
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Authors:
Gu‐Qing Zeng
Michael J. Quon
The Effects of Wortmannin on Rat Skeletal Muscle Publication Year: 1995
DOI: https://doi.org/10.1074/jbc.270.5.2107
Abstract:
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Authors:
Jih‐I Yeh
E. A. Gulve
Lucia E. Rameh
Morris J. Birnbaum
Inhibition of the translocation of GLUT1 and GLUT4 in 3T3-L1 cells by the phosphatidylinositol 3-kinase inhibitor, wortmannin Publication Year: 1994
DOI: https://doi.org/10.1042/bj3000631
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Authors:
James F. Clarke
Paul Young
Kazuyoshi Yonezawa
Masato Kasuga
Geoffrey D. Holman
Blockage of chemotactic peptide-induced stimulation of neutrophils by wortmannin as a result of selective inhibition of phosphatidylinositol 3-kinase. Publication Year: 1994
DOI: https://doi.org/10.1016/s0021-9258(17)41900-4
Abstract:
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Authors:
Taro Okada
L. Sakuma
Yoshinori Fukui
Osamu Hazeki
M Ui
The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated protein kinase pathway in L6 cells between Ras and Raf Publication Year: 1994
DOI: https://doi.org/10.1042/bj3030021
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Authors:
Darren A.E. Cross
Dario R. Alessi
Jackie R. Vandenheede
H E McDowell
Harinder S. Hundal
Philip Cohen
Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase Publication Year: 1995
DOI: https://doi.org/10.1016/s0968-0004(00)89056-8
Abstract:
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Authors:
Michio Ui
Taro Okada
Kaoru Hazeki
Osamu Hazeki
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