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464, 718], 'cancer': [149, 228, 273, 483, 697, 845, 870], 'was': [150, 159, 173, 181, 191, 229, 265, 288], 'examined.': [151], 'Materials': [152], 'Methods:': [154], 'A': [155, 960], 'prospective': [156], 'clinical': [157, 518], 'trial': [158, 519], 'conducted': [160], 'on': [161, 397, 415], '701': [162, 226], 'male': [163], 'volunteers': [164], '50': [165, 305, 312], 'years': [166, 565], 'old': [167, 566], 'or': [168, 186, 567], 'older.': [169], 'PSA': [172, 180, 204, 235, 263, 276, 279, 298, 322, 325, 333, 343], 'determined': [174], 'biopsies': [176, 222, 313, 338], 'were': [177, 314, 326], 'performed': [178, 223], 'if': [179, 187], 'greater': [182, 206, 290], 'than': [183, 207, 244, 294, 346], '4': [184, 208, 347, 394], 'ng./ml.': [185, 209, 348], 'digital': [188, 215, 245, 499], 'rectal': [189, 216, 246, 500, 850], 'examination': [190, 217, 247, 501], 'suspicious': [192, 214], 'for': [193, 272, 328, 400, 440, 466, 539, 557, 590, 640, 670, 720, 945, 1013], 'cancer.': [194], 'Results:': [195], 'Of': [196, 220, 1048, 1061, 1065], 'men': [198, 227, 340, 563, 795], '187': [199], '(27': [200], 'percent)': [201, 211, 243], 'had': [202], 'a': [203, 213, 342, 437, 463, 516, 581, 632, 716, 740, 743, 812, 1007], '(11': [210], 'and/or': [212], '(19': [218], 'percent).': [219, 234, 250], '116': [221], 'detected': [230, 236, 871], '13': [232, 625], '(1.9': [233], 'more': [237, 345], 'tumors': [238], '(12': [239], '13,': [241], '92': [242], '(9,': [248], '69': [249], 'Receiver': [251], 'operating': [252], 'characteristic': [253], 'analysis': [254], 'showed': [255], 'that': [256, 295, 309], 'optimal': [258], 'PSA-to-PSA': [260], 'ratio': [261, 280], '(free': [262], 'ratio)': [264], '12': [266, 302, 602], 'percent.': [267], 'positive': [269], 'predictive': [270, 769, 833], 'value': [271, 770, 834], 'according': [274, 296], 'with': [277, 316, 341, 349, 407, 634, 796, 848, 953], '(50': [281], 'percent,': [282, 301], '10': [283, 549], 'cancers': [284, 303, 319], '20': [286, 806], 'biopsies)': [287], 'significantly': [289], '(p': [291], '=': [292], '0.0473)': [293], 'alone': [299], '(24': [300], 'biopsies),': [306], 'which': [307], 'indicated': [308], '30': [310], 'avoided': [315], 'only': [317], '2': [318, 364], 'missed': [320, 351], 'when': [321], 'used': [327], 'biopsy': [329], 'indication.': [330], 'Conclusions:': [331], 'determination': [334], 'might': [335], 'eliminate': [336], 'unnecessary': [337], 'minimal': [350], 'cancers.': [352], 'References': [353], '1': [354], ':': [355, 365, 383, 395, 433, 454, 478, 496, 531, 550, 577, 603, 626, 655, 683, 705, 731, 758, 787, 807, 829, 866], 'statistics,': [357, 385], '1995..': [358], 'Ca1995;': [359], '45:': [360], '8.': [361], 'Google': [362, 380, 392, 430, 451, 475, 493, 528, 547, 574, 600, 623, 652, 680, 702, 728, 755, 784, 804, 826, 863, 888], 'Scholar': [363, 381, 393, 431, 452, 476, 494, 529, 548, 575, 601, 624, 653, 681, 703, 729, 756, 785, 805, 827, 864, 889], 'European': [369], 'community': [370], 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