Title: Comparative ultrastructure of tubular carcinoma and sclerosing adenosis of the breast
Abstract: CancerVolume 38, Issue 1 p. 180-186 ArticleFree Access Comparative ultrastructure of tubular carcinoma and sclerosing adenosis of the breast Wellington Jao MD, Corresponding Author Wellington Jao MD From the Department of Pathology, Michael Reese Hospital and Medical Center, Chicago, IllinoisDepartment of Pathology, Michael Reese Medical Center, Chicago, IL 60616===Search for more papers by this authorWendy Recant MD, Wendy Recant MD From the Department of Pathology, Michael Reese Hospital and Medical Center, Chicago, IllinoisSearch for more papers by this authorMartin A. Swerdlow MD, Martin A. Swerdlow MD From the Department of Pathology, Michael Reese Hospital and Medical Center, Chicago, IllinoisSearch for more papers by this author Wellington Jao MD, Corresponding Author Wellington Jao MD From the Department of Pathology, Michael Reese Hospital and Medical Center, Chicago, IllinoisDepartment of Pathology, Michael Reese Medical Center, Chicago, IL 60616===Search for more papers by this authorWendy Recant MD, Wendy Recant MD From the Department of Pathology, Michael Reese Hospital and Medical Center, Chicago, IllinoisSearch for more papers by this authorMartin A. Swerdlow MD, Martin A. Swerdlow MD From the Department of Pathology, Michael Reese Hospital and Medical Center, Chicago, IllinoisSearch for more papers by this author First published: July 1976 https://doi.org/10.1002/1097-0142(197607)38:1<180::AID-CNCR2820380128>3.0.CO;2-0Citations: 17AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Abstract The innocuous histologic appearance of tubular carcinoma of the breast and its superficial histologic resemblance to sclerosing adenosis will occasionally present diagnostic problems. A comparative ultrastructural analysis of two tubular carcinomas and three cases of sclerosing adenosis was made that showed definite differences in the pattern of myoepithelial cell differentiation and basal lamina deposition in these two entities. Prominent myoepithelial cells and basal lamina reduplication were both conspicuous features of sclerosing adenosis that appeared to be absent in tubular carcinoma. Intracytoplasmic "pseudo-cysts" were frequently found in sclerosing adenosis, but not in tubular carcinoma. Conversely, intracytoplasmic lumina and incomplete tubular structures were present in tubular carcinoma and seemingly absent in sclerosing adenosis. Such basic ultrastructural differences may help to differentiate these two mammary lesions when diagnostic problems occur at the conventional light microscopic level. Citing Literature Volume38, Issue1July 1976Pages 180-186 ReferencesRelatedInformation
Publication Year: 1976
Publication Date: 1976-07-01
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
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Cited By Count: 26
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