Peroxidative activation of <i>o</i>-phenylhydroquinone leads to the formation of DNA adducts in HL-60 cells

Name: Work Video:
Duration: 3 min 30 s
Éva Horváth; György Lévay; Krisztina Pongracz; William J. Bodell
{'id': 'https://openalex.org/W1992836365', 'doi': 'https://doi.org/10.1093/carcin/13.10.1937', 'title': 'Peroxidative activation of <i>o</i>-phenylhydroquinone leads to the formation of DNA adducts in HL-60 cells', 'display_name': 'Peroxidative activation of <i>o</i>-phenylhydroquinone leads to the formation of DNA adducts in HL-60 cells', 'publication_year': 1992, 'publication_date': '1992-01-01', 'ids': {'openalex': 'https://openalex.org/W1992836365', 'doi': 'https://doi.org/10.1093/carcin/13.10.1937', 'mag': '1992836365', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/1423859'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1093/carcin/13.10.1937', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S184620562', 'display_name': 'Carcinogenesis', 'issn_l': '0143-3334', 'issn': ['0143-3334', '1460-2180'], 'is_oa': False, 'is_in_doaj': False, 'is_indexed_in_scopus': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5063367530', 'display_name': 'Éva Horváth', 'orcid': 'https://orcid.org/0000-0002-6289-9192'}, 'institutions': [{'id': 'https://openalex.org/I4210157890', 'display_name': 'Neurological Surgery', 'ror': 'https://ror.org/04r0gp612', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210157890']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Eva Horvath', 'raw_affiliation_strings': ['Department of Neurological Surgery, University of California School of Medicine, San Francisco 94143'], 'affiliations': [{'raw_affiliation_string': 'Department of Neurological Surgery, University of California School of Medicine, San Francisco 94143', 'institution_ids': ['https://openalex.org/I4210157890']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5060721659', 'display_name': 'György Lévay', 'orcid': 'https://orcid.org/0000-0002-5865-6462'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Gyorgy Levay', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5055299797', 'display_name': 'Krisztina Pongracz', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Krisztina Pongracz', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5109836864', 'display_name': 'William J. Bodell', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I180670191', 'display_name': 'University of California, San Francisco', 'ror': 'https://ror.org/043mz5j54', 'country_code': 'US', 'type': 'funder', 'lineage': ['https://openalex.org/I180670191']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'William J. Bodell', 'raw_affiliation_strings': ['Department of Radiation Oncology, University of California, School of MedicineSan Francisco, CA 94143, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Radiation Oncology, University of California, School of MedicineSan Francisco, CA 94143, USA', 'institution_ids': ['https://openalex.org/I180670191']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 4428, 'currency': 'USD', 'value_usd': 4428, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 2.306, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 20, 'citation_normalized_percentile': {'value': 0.717624, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 84, 'max': 85}, 'biblio': {'volume': '13', 'issue': '10', 'first_page': '1937', 'last_page': '1939'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12356', 'display_name': 'Bioactive Compounds and Antitumor Agents', 'score': 0.9536, 'subfield': {'id': 'https://openalex.org/subfields/3005', 'display_name': 'Toxicology'}, 'field': {'id': 'https://openalex.org/fields/30', 'display_name': 'Pharmacology, Toxicology and Pharmaceutics'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12356', 'display_name': 'Bioactive Compounds and Antitumor Agents', 'score': 0.9536, 'subfield': {'id': 'https://openalex.org/subfields/3005', 'display_name': 'Toxicology'}, 'field': {'id': 'https://openalex.org/fields/30', 'display_name': 'Pharmacology, Toxicology and Pharmaceutics'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10433', 'display_name': 'Carcinogens and Genotoxicity Assessment', 'score': 0.934, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/dna-adduct', 'display_name': 'DNA adduct', 'score': 0.5606088}], 'concepts': [{'id': 'https://openalex.org/C108204754', 'wikidata': 'https://www.wikidata.org/wiki/Q353392', 'display_name': 'Adduct', 'level': 2, 'score': 0.9587939}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.7608841}, {'id': 'https://openalex.org/C552990157', 'wikidata': 'https://www.wikidata.org/wiki/Q7430', 'display_name': 'DNA', 'level': 2, 'score': 0.69956577}, {'id': 'https://openalex.org/C114246631', 'wikidata': 'https://www.wikidata.org/wiki/Q187661', 'display_name': 'Carcinogen', 'level': 2, 'score': 0.6400984}, {'id': 'https://openalex.org/C512185932', 'wikidata': 'https://www.wikidata.org/wiki/Q28745', 'display_name': 'Nucleotide', 'level': 3, 'score': 0.6241114}, {'id': 'https://openalex.org/C2781247443', 'wikidata': 'https://www.wikidata.org/wiki/Q4153410', 'display_name': 'DNA adduct', 'level': 3, 'score': 0.5606088}, {'id': 'https://openalex.org/C162008176', 'wikidata': 'https://www.wikidata.org/wiki/Q419305', 'display_name': 'Peroxidase', 'level': 3, 'score': 0.4162814}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.39908415}, {'id': 'https://openalex.org/C71240020', 'wikidata': 'https://www.wikidata.org/wiki/Q186011', 'display_name': 'Stereochemistry', 'level': 1, 'score': 0.3979334}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.35873625}, {'id': 'https://openalex.org/C178790620', 'wikidata': 'https://www.wikidata.org/wiki/Q11351', 'display_name': 'Organic chemistry', 'level': 1, 'score': 0.10172126}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.05195844}], 'mesh': [{'descriptor_ui': 'D001713', 'descriptor_name': 'Biphenyl Compounds', 'qualifier_ui': 'Q000493', 'qualifier_name': 'pharmacokinetics', 'is_major_topic': True}, {'descriptor_ui': 'D004273', 'descriptor_name': 'DNA, Neoplasm', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D006873', 'descriptor_name': 'Hydroquinones', 'qualifier_ui': 'Q000493', 'qualifier_name': 'pharmacokinetics', 'is_major_topic': True}, {'descriptor_ui': 'D007942', 'descriptor_name': 'Leukemia, Experimental', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D007951', 'descriptor_name': 'Leukemia, Myeloid', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D016227', 'descriptor_name': 'Benzoquinones', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001711', 'descriptor_name': 'Biotransformation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001713', 'descriptor_name': 'Biphenyl Compounds', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001713', 'descriptor_name': 'Biphenyl Compounds', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D001713', 'descriptor_name': 'Biphenyl Compounds', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D004273', 'descriptor_name': 'DNA, Neoplasm', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004273', 'descriptor_name': 'DNA, Neoplasm', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006873', 'descriptor_name': 'Hydroquinones', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006873', 'descriptor_name': 'Hydroquinones', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D006873', 'descriptor_name': 'Hydroquinones', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D007942', 'descriptor_name': 'Leukemia, Experimental', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007951', 'descriptor_name': 'Leukemia, Myeloid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010084', 'descriptor_name': 'Oxidation-Reduction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014407', 'descriptor_name': 'Tumor Cells, Cultured', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1093/carcin/13.10.1937', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S184620562', 'display_name': 'Carcinogenesis', 'issn_l': '0143-3334', 'issn': ['0143-3334', '1460-2180'], 'is_oa': False, 'is_in_doaj': False, 'is_indexed_in_scopus': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/1423859', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_indexed_in_scopus': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W4390079342', 'https://openalex.org/W2563277212', 'https://openalex.org/W2523454193', 'https://openalex.org/W2079095316', 'https://openalex.org/W2030434415', 'https://openalex.org/W2027941205', 'https://openalex.org/W2001329454', 'https://openalex.org/W1999502608', 'https://openalex.org/W1975102042', 'https://openalex.org/W1974263506'], 'abstract_inverted_index': {'Journal': [0], 'Article': [1, 141], 'Peroxidative': [2], 'activation': [3], 'of': [4, 10, 77, 81, 84, 101], 'o-phenylhydroquinone': [5], 'leads': [6], 'to': [7], 'the': [8], 'formation': [9], 'DNA': [11], 'adducts': [12], 'in': [13], 'HL-60': [14], 'cells': [15], 'Get': [16], 'access': [17], 'Eva': [18, 20], 'Horvath,': [19], 'Horvath': [21], 'Search': [22, 39, 56, 114], 'for': [23, 40, 57, 115], 'other': [24, 41, 58, 116], 'works': [25, 42, 59, 117], 'by': [26, 43, 60, 118], 'this': [27, 44, 61, 119], 'author': [28, 45, 62, 120], 'on:': [29, 46, 63, 121], 'Oxford': [30, 47, 64, 122], 'Academic': [31, 48, 65, 123], 'PubMed': [32, 49, 66, 124], 'Google': [33, 50, 67, 125], 'Scholar': [34, 51, 68, 126], 'Gyorgy': [35, 37], 'Levay,': [36], 'Levay': [38], 'Krisztina': [52, 54], 'Pongracz,': [53], 'Pongracz': [55], 'William': [69, 72], 'J.': [70, 73], 'Bodell': [71, 74], '2': [75], '1Department': [76], 'Radiation': [78], 'Oncology,': [79], 'University': [80], 'California,': [82], 'School': [83], 'MedicineSan': [85], 'Francisco,': [86, 110], 'CA': [87, 111], '94143,': [88], 'USA': [89, 113], '2To': [90], 'whom': [91], 'correspondence': [92], 'should': [93], 'be': [94], 'addressed': [95], 'at:': [96], 'The': [97], 'Editorial': [98], 'Office,': [99], 'Department': [100], 'Neurological': [102], 'Surgery,': [103], 'Suite': [104], '210,': [105], '1360': [106], 'Ninth': [107], 'Avenue,': [108], 'San': [109], '94122,': [112], 'Carcinogenesis,': [127], 'Volume': [128], '13,': [129], 'Issue': [130], '10,': [131], 'October': [132, 139, 158], '1992,': [133], 'Pages': [134], '1937–1939,': [135], 'https://doi.org/10.1093/carcin/13.10.1937': [136], 'Published:': [137, 156], '01': [138, 157], '1992': [140, 146, 151, 155, 159], 'history': [142], 'Received:': [143], '24': [144], 'February': [145], 'Revision': [147], 'received:': [148], '09': [149], 'June': [150, 154], 'Accepted:': [152], '25': [153]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1992836365', 'counts_by_year': [], 'updated_date': '2025-01-26T20:33:12.565396', 'created_date': '2016-06-24'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
