A comparison of aztreonam plus vancomycin and imipenem plus vancomycin as initial therapy for febrile neutropenic cancer patients

Name: Work Video:
Duration: 3 min 30 s
Issam Raad; Estella Whimbey; Kenneth Rolston; Dima Abi-Said; Ray Hachem; Rajendra G. Pandya; Habib M. Ghaddar; Cynthia L. Karl; Gerald P. Bodey
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[959, 1234, 1298, 1372, 1757], 'Serpick': [960], 'A.': [961, 1379], 'Empiric': [962, 1931], 'carbenicillin': [965, 1165], 'gentamicin': [967, 1167, 1640, 1688, 1793], 'granulocytopenia.': [974, 1938], 'N': [975, 1052, 1218], 'Engl': [976, 1053, 1219], 'J': [977, 1054, 1132, 1175, 1220, 1324, 1355, 1537, 1569, 1612, 1700, 1741, 1772, 1811, 1940, 1969, 1996, 2028, 2048, 2128, 2239, 2309], '1971;': [979], '284:': [980], '1061–5.': [981], '10.1056/NEJM197105132841904': [982], 'PubMedWeb': [983, 1008, 1139, 1182, 1396, 1661, 1747, 1817, 1975, 2003, 2135, 2170, 2274, 2316], '3': [987], 'SC.': [989], 'Overview': [990], 'antibiotic': [993, 1017, 1209, 2069], 'patient.': [999, 2290], 'Rev': [1000, 1030, 1249], 'Infect': [1001, 1031, 1096, 1133, 1250, 1325, 1567, 1843, 2214], 'Dis': [1002, 1032, 1097, 1134, 1251, 1326, 1568, 1844], '1985;': [1003], '7(suppl': [1004], '4):': [1005], 'S734–S40.': [1006], '10.1093/clinids/7.Supplement_4.S734': [1007], '4': [1012], 'GP.': [1014, 1238, 1763], 'Evolution': [1015], 'patients:': [1023, 1317, 1733, 1806, 1992, 2019], 'studies': [1024], 'at': [1025], 'Hospital.': [1029], '1989;': [1033, 1392], '11(7):': [1034], '1582S–90S.': [1035], '10.1093/clinids/11.Supplement_7.S1582': [1036], 'Google': [1037, 1102, 1256, 1330, 2036], '5': [1039], 'Pizzo': [1040, 1067, 1187], 'PA.': [1041], 'Management': [1042], 'fever': [1044, 1215, 1560, 1728, 1803], 'treatment-induced': [1050, 1937], 'neutropenia.': [1051, 1217, 1418], '1993;': [1056, 2166, 2194], '328(18):': [1057], '1323–32.': [1058], '10.1056/NEJM199305063281808': [1059], 'Hughes': [1065, 1105], 'WT,': [1066, 1106], 'PA,': [1068, 1188], 'Wade': [1069], 'JC,': [1070], 'Armstrong': [1071, 1107, 1958], 'D,': [1072, 1074, 1108, 1196, 1717, 2101], 'Webb': [1073], 'LS.': [1076], 'General': [1077], 'guidelines': [1078], 'evaluation': [1081], 'new': [1083], 'anti-infective': [1084], 'drugs': [1085], 'patients.': [1094, 1174, 1278, 1354, 1390, 1454, 1497, 1653, 2074], 'Clin': [1095, 1538, 1742, 1842, 2030], '1992;': [1098, 1501, 1657, 1703, 1813, 1845], '15(suppl):': [1099], '206S–15S.': [1100], '10.1093/clind/15.Supplement_1.S206': [1101], 'Feld': [1111], 'F,': [1112, 1370, 1629], 'Mandell': [1113], 'GL,': [1114], 'Meyers': [1115], 'JD,': [1116, 1920], 'et': [1117, 1199, 1303, 1345, 1443, 1479, 1592, 1636, 1678, 1724, 1929, 2152], 'al.': [1118, 1200, 1304, 1346, 1444, 1480, 1593, 1637, 1679, 1725, 1930, 2153], 'Guidelines': [1119], 'use': [1122, 1932], 'antimicrobial': [1124, 2232], 'agents': [1125], 'unexplained': [1130], 'fever.': [1131], '1990;': [1135, 1422, 1458, 1876, 2032, 2050, 2311], '161:': [1136], '381–96.': [1137], '10.1093/infdis/161.3.381': [1138], '8': [1143], 'Ramphal': [1144], 'R,': [1145, 1232, 1334, 1336, 1432, 1434, 1673], 'Kramer': [1146], 'BS,': [1147], 'Rand': [1148], 'KH,': [1149], 'Weiner': [1150], 'RS,': [1151, 1761, 2145], 'Shands': [1152], 'JW': [1153], 'Jr.': [1154], 'Early': [1155], 'results': [1156, 2020], 'comparative': [1159, 1681], 'ceftazidime': [1162, 1205, 1486, 1553, 1738, 2082], 'versus': [1163, 1306, 1381, 1446, 1639, 1685, 1739, 1792, 2124], 'cephalothin,': [1164], 'granulocytopenic': [1173, 1991, 2017, 2073], 'Antimicrob': [1176, 1279, 1356, 1455, 1654, 1701, 1997, 2129], 'Chemother': [1177, 1281, 1357, 1457, 1656, 1702, 1812, 1998, 2130], '1983;': [1178, 1252, 1909], '12(suppl):': [1179], '81–8.': [1180], '10.1093/jac/12.suppl_A.81': [1181], '9': [1186], 'Hathorn': [1189, 1722], 'JW,': [1190], 'Hiemen': [1191], 'J,': [1192, 1198, 1406, 1635, 1671, 1719, 1723, 2147], 'Brown': [1193], 'Cotton': [1195], 'Gross': [1197], 'randomized': [1202, 1320, 1520, 1735, 1808, 2024, 2076, 2118], 'alone': [1206, 1524], 'combination': [1208], '1986;': [1222, 1282, 1774, 1942, 2292], '315:': [1223], '552–8.': [1224], '10.1056/NEJM198608283150905': [1225], '10': [1230], 'Boliver': [1231], 'Fainstein': [1233, 1269, 1756, 2283], 'Elting': [1235, 1758, 1822, 2279], 'L,': [1236, 1268, 1759, 1926], 'Cefoperazone': [1239], '5(suppl):': [1253], '181S–7S.': [1254], '10.1093/clinids/5.Supplement_1.S181': [1255], '11': [1258], 'Alvarez': [1261], 'ME,': [1262], 'Jones': [1263, 1752], 'KV,': [1266], 'Steelhammer': [1267], 'Imipenem-Cilastatin': [1271], 'Agents': [1280, 1456, 1655], '30:': [1283, 1704], '211–4.': [1284], '10.1128/AAC.30.2.211': [1285], 'Noorby': [1291], 'SR,': [1292], 'Vandercam': [1293], 'BB,': [1294], 'Louie': [1295], 'T,': [1296, 1631, 1715], 'Runde': [1297], 'Norberg': [1299], 'B,': [1300], 'Anniko': [1301], 'Imipenem/Cilastatin': [1305], 'Amikacin': [1307], 'Piperacillin': [1309], 'multi-clinic': [1321], 'study.': [1322, 1810], 'Scand': [1323], '1987;': [1327, 1971], '52:': [1328], '65–78.': [1329], '13': [1332], 'Liang': [1333, 1431], 'Yung': [1335, 1433], 'Chau': [1337, 1437], 'PY,': [1338], 'Chan': [1339, 1439], 'TK,': [1340], 'Lam': [1341, 1441], 'WK,': [1342], 'So': [1343], 'SY,': [1344], 'Imipenem/cilastatin': [1347], '1988;': [1358, 1999], '22:': [1359], '765–70.': [1360], '10.1093/jac/22.5.765': [1361], '14': [1366], 'Bucaneve': [1367], 'G,': [1368], 'Menichetti': [1369], 'Minotti': [1371], 'Pasticci': [1373], 'MB,': [1374], 'Toato': [1375], 'Del': [1377], 'Favero': [1378], 'Ceftriaxone': [1380], 'empirical': [1384, 1596, 1797], 'monotherapy': [1385, 1412, 1450], 'Chemotherapy': [1391], '35(suppl):': [1393], '10–5.': [1394], '10.1159/000238733': [1395], '15': [1400], 'Hauer': [1401], 'C,': [1402, 1404, 1922, 1981, 2149], 'Urban': [1403], 'Slavc': [1405], 'Gamillscheg': [1407], 'A,': [1408, 1627], 'Lackner': [1409], 'H.': [1410], 'Imipenem-antibiotic': [1411], 'juvenile': [1414], 'Pediatr': [1419, 1566], 'Hematol': [1420], 'Oncol': [1421, 1539, 1743, 2031], '7:': [1423], '229–41.': [1424], '10.3109/08880019009033398': [1425], '16': [1430], 'Chiu': [1435], 'E,': [1436, 1786, 1857, 1952, 2151], 'P-Y,': [1438], 'T-K,': [1440], 'W-K,': [1442], 'Ceftazidime': [1445], 'imipenem-cilastatin': [1447], '34(7):': [1459], '1336–41.': [1460], '10.1128/AAC.34.7.1336': [1461], '17': [1466], 'KVI,': [1468, 1755], 'Berkey': [1469], 'P,': [1470, 1924, 1956, 1985, 2107], 'Anaissie': [1473], 'EJ,': [1474], 'Khardori': [1475], 'NM,': [1476], 'Joshi': [1477], 'JH,': [1478], 'without': [1489], 'amikacin': [1490], 'Arch': [1498, 1906], '152:': [1502], '283–91.': [1503], '18': [1508], 'Matsui': [1509], 'K,': [1510, 2143], 'Masuda': [1511], 'N,': [1512], 'Takada': [1513], 'Kusunoki': [1515], 'Y,': [1516], 'Fukuoka': [1517], 'latamoxef': [1526], 'tobramycin': [1528], 'lung': [1534], 'Jpn': [1536], '1991;': [1540, 1570, 1614, 2091, 2131], '21(6):': [1541], '428–34.': [1542], '19': [1547], 'Riikonen': [1548], 'Imipenem': [1550, 1638], 'van-comycin': [1555], 'children': [1563, 2113], '10:': [1571], '918–23.': [1572], '10.1097/00006454-199112000-00008': [1573], '20': [1578], 'Huijgens': [1579], 'PC,': [1580], 'Ossenkoppele': [1581], 'GJ,': [1582], 'Weijers': [1583], 'TF,': [1584], 'van': [1585, 1982], 'Loenen': [1586], 'AC,': [1587, 1675], 'Simoons-Smit': [1588], 'AM,': [1589], 'Wijermans': [1590], 'PW,': [1591], 'Imipenem-cilastatin': [1594], 'fever:': [1602], 'an': [1603, 1993], 'open': [1604], 'study': [1605, 1682, 1838, 2230], 'hematologic': [1609], 'malignancies.': [1610, 1699], 'Eur': [1611, 2027], 'Haematol': [1613], '46:': [1615], '42–6.': [1616], '10.1111/j.1600-0609.1991.tb00512.x': [1617], '21': [1622], 'Cornelissen': [1623], 'JJ,': [1624], 'de': [1625], 'Graeff': [1626], 'Verdonck': [1628], 'Branger': [1630], 'Rozenberg-Arska': [1632], 'Verhoef': [1634], 'combined': [1641], 'either': [1643], 'cefuroxime': [1644], 'cephalothin': [1646], '36(4):': [1658], '801–7.': [1659], '10.1128/AAC.36.4.801': [1660], '22': [1665], 'Leyland': [1666], 'MJ,': [1667, 2254], 'Bayston': [1668], 'KF,': [1669], 'Cohen': [1670], 'Warren': [1672], 'Newland': [1674, 1787], 'Bint': [1676], 'AJ,': [1677], 'piper-acillin': [1686], 'management': [1692], 'haematological': [1698], '843–54.': [1705], '10.1093/jac/30.6.843': [1706], '23': [1711], 'Freifeld': [1712], 'AG,': [1713], 'Walsh': [1714], 'Marshall': [1716], 'Gress': [1718], 'Steinberg': [1720], 'SM,': [1721, 1784], 'Monotherapy': [1726], 'imipenem.': [1740], '1995;': [1744, 2218], '13(1):': [1745], '165–76.': [1746], '24': [1751], 'PG,': [1753], 'Walters': [1760], 'Aztreonam': [1764, 1789, 2041, 2110], 'Am': [1771, 1939, 1968, 2047, 2238, 2308], '81:': [1775, 1943], '243–8.': [1776], '10.1016/0002-9343(86)90258-5': [1777], '25': [1782], 'Kelsey': [1783], 'Shaw': [1785], 'AC.': [1788], 'piperacillin': [1795, 2125], 'controlled': [1809], '4(2):': [1814], '107–13.': [1815], '10.1080/1120009X.1992.11739149': [1816], '26': [1821], 'LS,': [1823, 2280], 'Keefe': [1826], 'BH.': [1827], 'Septicemia': [1828], 'shock': [1830], 'syndrome': [1831], 'due': [1832], 'viridans': [1834], 'streptococci:': [1835], 'case-control': [1837], 'predisposing': [1840], 'factors.': [1841], '14:': [1846], '1201–7.': [1847], '10.1093/clinids/14.6.1201': [1848], '27': [1853], 'Kern': [1854], 'Jurrie': [1856], 'Schmeiser': [1858], 'T.': [1859], 'Streptococcal': [1860], 'bacteremia': [1861, 1900, 2015], 'adult': [1863], 'leukemia': [1866], 'undergoing': [1867], 'aggressive': [1868], 'chemotherapy.': [1869], '55': [1873], 'cases.': [1874], 'Infection': [1875], '18:': [1877], '138–45.': [1878], '10.1007/BF01642101': [1879], '28': [1884], 'Winston': [1885, 2060], 'DJ,': [1886, 2061], 'Dudnick': [1887], 'DV,': [1888], 'Chapin': [1889], 'Ho': [1891, 2062], 'WG,': [1892, 2063], 'Gale': [1893], 'RP,': [1894], 'Martin': [1895], 'WJ.': [1896], 'Coagulase': [1897], 'negative': [1898], 'staphylcoccal': [1899], 'receiving': [1903], 'immunosupplressive': [1904], 'therapy.': [1905], '143:': [1910], '32–6.': [1911], '29': [1916], 'Karp': [1917], 'JE,': [1918], 'Dick': [1919], 'Angelopoulos': [1921], 'Charache': [1923], 'Green': [1925], 'Burke': [1927], 'PJ,': [1928], 'during': [1935], 'prolonged': [1936], '237–42.': [1944], '10.1016/0002-9343(86)90257-3': [1945], '30': [1950], 'Kiehn': [1953], 'TE,': [1954], 'Brannon': [1955], 'Blevins,': [1957], 'Bacteremia': [1960], 'fungemia': [1962], 'neoplastic': [1966], 'disease.': [1967], '82:': [1972], '723–9.': [1973], '10.1016/0002-9343(87)90007-6': [1974], '31': [1979], 'Viscoli': [1980], 'der': [1983], 'Auwera': [1984], 'Meunier': [1986], 'F.': [1987], 'Gram-positive': [1988, 2014], 'important': [1994], 'issue?': [1995], '21(suppl):': [2000], '149–56.': [2001], '10.1093/jac/21.suppl_C.149': [2002], '32': [2007], 'EORTC': [2008], 'International': [2009], 'Antimicrobial': [2010], 'Therapy': [2011], 'Cooperative': [2012], 'Group.': [2013], 'therapeutic': [2025], 'trial.': [2026], '26(5):': [2033], '569–74.': [2034], '10.1016/0277-5379(90)90079-9': [2035], '33': [2038], 'Neu': [2039], 'HC.': [2040], 'activity,': [2042], 'pharmacology,': [2043], 'use.': [2046], '88(suppl': [2051, 2312], '3C):': [2052, 2313], '2–6.': [2053], '10.1016/0002-9343(90)90079-S': [2054], 'Web': [2055], '34': [2059], 'Bruckner': [2064], 'DA,': [2065], 'Champlin': [2066], 'RE.': [2067], 'Beta-lactam': [2068], 'cefoperazone': [2079], 'piperacillin,': [2081, 2084], 'alone.': [2087], '115:': [2092], '849–59.': [2093], '10.7326/0003-4819-115-11-849': [2094], '35': [2099], 'Heney': [2100], 'Lewis': [2102], 'IJ,': [2103], 'Ghoneim': [2104], 'ATM,': [2105], 'Chisholm': [2106], 'Bailey': [2108], 'CC.': [2109], 'neutropenia:': [2116], 'flucloxacillin': [2123], 'gentamicin.': [2127], '28:': [2132], '117–29.': [2133], '10.1093/jac/28.1.117': [2134], '36': [2139], 'Rubenstein': [2140], 'EB,': [2141], 'Benjamin': [2144], 'Loewy': [2146], 'Escalante': [2148], 'Manzullo': [2150], 'Outpatient': [2154], 'low-risk': [2160], '71(11):': [2167], '3640–6.': [2168], '10.1002/1097-0142(19930601)71:11<3640::AID-CNCR2820711128>3.0.CO;2-H': [2169], '37': [2174], 'Centers': [2175, 2200], 'Disease': [2177, 2202], 'Control': [2178, 2203, 2215], 'Prevention.': [2180, 2205], 'Nosocomial': [2181], 'enterococci': [2182], 'resistant': [2183], '-': [2186], 'United': [2187], 'States,': [2188], '1989–1993.': [2189], 'Morb': [2190], 'Mortal': [2191], 'Wkly': [2192], 'Rep': [2193], '42:': [2195], '597–9.': [2196], 'PubMedGoogle': [2197, 2222], '38': [2199], 'Recommendations': [2206], 'preventing': [2208], 'spread': [2210], 'resistance.': [2213], 'Hosp': [2216], 'Epidemiol': [2217], '16(2):': [2219], '105–12.': [2220], '10.1086/647066': [2221], '39': [2224], 'Maki': [2225], 'DG,': [2226], 'Schuma': [2227], 'AA.': [2228], 'misuse': [2233], 'university': [2236], 'hospital.': [2237], 'Sci': [2241], '1978;': [2242], '275:': [2243], '271–82.': [2244], '10.1097/00000441-197805000-00005': [2245], '40': [2250], 'Estey': [2251], 'EH,': [2252], 'Keating': [2253], 'McCredie': [2255], 'KB,': [2256], 'Causes': [2261], 'remission': [2263], 'induction': [2264], 'failure': [2265], 'myelogenous': [2268], 'Blood': [2270], '1982;': [2271], '60:': [2272], '309–15.': [2273], '41': [2278], 'Polymicrobial': [2285], 'septicemia': [2286], 'Medicine': [2291], '65:': [2293], '218–25.': [2294], '10.1097/00005792-198607000-00002': [2295], '42': [2300], 'Adkinson': [2301], 'NF.': [2302], 'Immunogenicity': [2303], 'cross-allergenicity': [2305], 'aztreonam.': [2307], '12–5.': [2314], '10.1016/0002-9343(90)90081-N': [2315], 'Citing': [2320], 'Literature': [2321], 'Volume77,': [2322], 'Issue71': [2323], '1996Pages': [2325], 'ReferencesRelatedInformation': [2327]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1992197171', 'counts_by_year': [{'year': 2022, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 3}, {'year': 2013, 'cited_by_count': 1}], 'updated_date': '2024-12-09T04:11:09.054247', 'created_date': '2016-06-24'}
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