Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2004008520', 'doi': 'https://doi.org/10.1086/314028', 'title': 'Vancomycin-Induced Neutropenia Resolves after Substitution with Teicoplanin', 'display_name': 'Vancomycin-Induced Neutropenia Resolves after Substitution with Teicoplanin', 'publication_year': 2000, 'publication_date': '2000-09-01', 'ids': {'openalex': 'https://openalex.org/W2004008520', 'doi': 'https://doi.org/10.1086/314028', 'mag': '2004008520', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/11017842'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1086/314028', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S72350973', 'display_name': 'Clinical Infectious Diseases', 'issn_l': '1058-4838', 'issn': ['1058-4838', '1537-6591'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5061107241', 'display_name': 'Stephen Sanche', 'orcid': 'https://orcid.org/0000-0003-3643-5973'}, 'institutions': [{'id': 'https://openalex.org/I4210109567', 'display_name': 'Office of Infectious Diseases', 'ror': 'https://ror.org/01z6p8p31', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1289490764', 'https://openalex.org/I1299022934', 'https://openalex.org/I4210109567']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'Stephen E. Sanche', 'raw_affiliation_strings': ['Department of Microbiology and Immunology', 'Division of Infectious Diseases, Department of Medicine'], 'affiliations': [{'raw_affiliation_string': 'Division of Infectious Diseases, Department of Medicine', 'institution_ids': ['https://openalex.org/I4210109567']}, {'raw_affiliation_string': 'Department of Microbiology and Immunology', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5075033764', 'display_name': 'William Dust', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2801053234', 'display_name': 'Royal University Hospital', 'ror': 'https://ror.org/00wg2b048', 'country_code': 'CA', 'type': 'healthcare', 'lineage': ['https://openalex.org/I23625684', 'https://openalex.org/I2801053234']}], 'countries': ['CA'], 'is_corresponding': False, 'raw_author_name': 'William N. Dust', 'raw_affiliation_strings': ['Division of Orthopedic Surgery, Department of Surgery, Royal University Hospital'], 'affiliations': [{'raw_affiliation_string': 'Division of Orthopedic Surgery, Department of Surgery, Royal University Hospital', 'institution_ids': ['https://openalex.org/I2801053234']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5109399907', 'display_name': 'Yvonne Shevchuk', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I32625721', 'display_name': 'University of Saskatchewan', 'ror': 'https://ror.org/010x8gc63', 'country_code': 'CA', 'type': 'education', 'lineage': ['https://openalex.org/I32625721']}, {'id': 'https://openalex.org/I4210109567', 'display_name': 'Office of Infectious Diseases', 'ror': 'https://ror.org/01z6p8p31', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1289490764', 'https://openalex.org/I1299022934', 'https://openalex.org/I4210109567']}], 'countries': ['CA', 'US'], 'is_corresponding': False, 'raw_author_name': 'Yvonne M. Shevchuk', 'raw_affiliation_strings': ['College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, Canada', 'Division of Infectious Diseases, Department of Medicine'], 'affiliations': [{'raw_affiliation_string': 'College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, Canada', 'institution_ids': ['https://openalex.org/I32625721']}, {'raw_affiliation_string': 'Division of Infectious Diseases, Department of Medicine', 'institution_ids': ['https://openalex.org/I4210109567']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 3, 'corresponding_author_ids': ['https://openalex.org/A5061107241'], 'corresponding_institution_ids': ['https://openalex.org/I4210109567'], 'apc_list': {'value': 4320, 'currency': 'USD', 'value_usd': 4320, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.933, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 27, 'citation_normalized_percentile': {'value': 0.777873, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 87, 'max': 88}, 'biblio': {'volume': '31', 'issue': '3', 'first_page': '824', 'last_page': '825'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12919', 'display_name': 'Blood disorders and treatments', 'score': 0.9992, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12919', 'display_name': 'Blood disorders and treatments', 'score': 0.9992, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10195', 'display_name': 'Antimicrobial Resistance in Staphylococcus', 'score': 0.9981, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12172', 'display_name': 'Neutropenia and Cancer Infections', 'score': 0.9793, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/teicoplanin', 'display_name': 'Teicoplanin', 'score': 0.9106936}, {'id': 'https://openalex.org/keywords/discontinuation', 'display_name': 'Discontinuation', 'score': 0.78676814}], 'concepts': [{'id': 'https://openalex.org/C2778980435', 'wikidata': 'https://www.wikidata.org/wiki/Q424027', 'display_name': 'Vancomycin', 'level': 4, 'score': 0.9335844}, {'id': 'https://openalex.org/C2777063308', 'wikidata': 'https://www.wikidata.org/wiki/Q1435822', 'display_name': 'Neutropenia', 'level': 3, 'score': 0.9152451}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.91339314}, {'id': 'https://openalex.org/C2776703206', 'wikidata': 'https://www.wikidata.org/wiki/Q2731762', 'display_name': 'Teicoplanin', 'level': 5, 'score': 0.9106936}, {'id': 'https://openalex.org/C2778715236', 'wikidata': 'https://www.wikidata.org/wiki/Q55622662', 'display_name': 'Discontinuation', 'level': 2, 'score': 0.78676814}, {'id': 'https://openalex.org/C501593827', 'wikidata': 'https://www.wikidata.org/wiki/Q12187', 'display_name': 'Antibiotics', 'level': 2, 'score': 0.5602745}, {'id': 'https://openalex.org/C197934379', 'wikidata': 'https://www.wikidata.org/wiki/Q2047938', 'display_name': 'Adverse effect', 'level': 2, 'score': 0.50527316}, {'id': 'https://openalex.org/C177713679', 'wikidata': 'https://www.wikidata.org/wiki/Q679690', 'display_name': 'Intensive care medicine', 'level': 1, 'score': 0.36224118}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.33817}, {'id': 'https://openalex.org/C2776694085', 'wikidata': 'https://www.wikidata.org/wiki/Q974135', 'display_name': 'Chemotherapy', 'level': 2, 'score': 0.23045653}, {'id': 'https://openalex.org/C2779489039', 'wikidata': 'https://www.wikidata.org/wiki/Q188121', 'display_name': 'Staphylococcus aureus', 'level': 3, 'score': 0.12847278}, {'id': 'https://openalex.org/C89423630', 'wikidata': 'https://www.wikidata.org/wiki/Q7193', 'display_name': 'Microbiology', 'level': 1, 'score': 0.09063521}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C523546767', 'wikidata': 'https://www.wikidata.org/wiki/Q10876', 'display_name': 'Bacteria', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000900', 'descriptor_name': 'Anti-Bacterial Agents', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': True}, {'descriptor_ui': 'D009503', 'descriptor_name': 'Neutropenia', 'qualifier_ui': 'Q000139', 'qualifier_name': 'chemically induced', 'is_major_topic': True}, {'descriptor_ui': 'D017334', 'descriptor_name': 'Teicoplanin', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D014640', 'descriptor_name': 'Vancomycin', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': True}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000900', 'descriptor_name': 'Anti-Bacterial Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000900', 'descriptor_name': 'Anti-Bacterial Agents', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009503', 'descriptor_name': 'Neutropenia', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013203', 'descriptor_name': 'Staphylococcal Infections', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013203', 'descriptor_name': 'Staphylococcal Infections', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D013211', 'descriptor_name': 'Staphylococcus aureus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013211', 'descriptor_name': 'Staphylococcus aureus', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D017334', 'descriptor_name': 'Teicoplanin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014640', 'descriptor_name': 'Vancomycin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014640', 'descriptor_name': 'Vancomycin', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1086/314028', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S72350973', 'display_name': 'Clinical Infectious Diseases', 'issn_l': '1058-4838', 'issn': ['1058-4838', '1537-6591'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/11017842', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.72, 'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 10, 'referenced_works': ['https://openalex.org/W1967626174', 'https://openalex.org/W1994286358', 'https://openalex.org/W2107751022', 'https://openalex.org/W2121441889', 'https://openalex.org/W2150799152', 'https://openalex.org/W2403297188', 'https://openalex.org/W2418286232', 'https://openalex.org/W348492191', 'https://openalex.org/W4229782939', 'https://openalex.org/W4243591410'], 'related_works': ['https://openalex.org/W2742145376', 'https://openalex.org/W2413336447', 'https://openalex.org/W2358019477', 'https://openalex.org/W2184058138', 'https://openalex.org/W2161013162', 'https://openalex.org/W2153012695', 'https://openalex.org/W2141050213', 'https://openalex.org/W2040640485', 'https://openalex.org/W2005185244', 'https://openalex.org/W1514265259'], 'abstract_inverted_index': {'Neutropenia': [0], 'is': [1], 'an': [2], 'uncommon': [3], 'adverse': [4], 'effect': [5], 'associated': [6], 'with': [7], 'prolonged': [8], 'vancomycin': [9, 18, 48], 'therapy.': [10, 34], 'Neutrophil': [11], 'counts': [12], 'normally': [13], 'recover': [14], 'after': [15, 47], 'discontinuation': [16], 'of': [17, 39], 'in': [19, 42], 'this': [20], 'situation,': [21], 'but': [22], 'treatment': [23], 'options': [24], 'are': [25], 'needed': [26], 'for': [27], 'those': [28], 'patients': [29], 'who': [30], 'require': [31], 'ongoing': [32], 'antibiotic': [33], 'We': [35], 'describe': [36], 'a': [37], 'case': [38], 'vancomycin-induced': [40], 'neutropenia': [41, 45], 'which': [43], 'the': [44, 52], 'resolved': [46], 'was': [49], 'replaced': [50], 'by': [51], 'structurally': [53], 'related': [54], 'compound': [55], 'teicoplanin.': [56]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2004008520', 'counts_by_year': [{'year': 2019, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-12-11T05:24:54.187088', 'created_date': '2016-06-24'}