Publication Information

{'id': 'https://openalex.org/W1991903436', 'doi': 'https://doi.org/10.3899/jrheum.100889', 'title': 'The Role of HLA-B27 in Spondyloarthritis', 'display_name': 'The Role of HLA-B27 in Spondyloarthritis', 'publication_year': 2010, 'publication_date': '2010-12-01', 'ids': {'openalex': 'https://openalex.org/W1991903436', 'doi': 'https://doi.org/10.3899/jrheum.100889', 'mag': '1991903436', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/21123333'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3899/jrheum.100889', 'pdf_url': 'https://www.jrheum.org/content/jrheum/37/12/2606.full.pdf', 'source': {'id': 'https://openalex.org/S50602745', 'display_name': 'The Journal of Rheumatology', 'issn_l': '0315-162X', 'issn': ['0315-162X', '1499-2752'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320417', 'host_organization_name': 'The Journal of Rheumatology Publishing Company Limited', 'host_organization_lineage': ['https://openalex.org/P4310320417'], 'host_organization_lineage_names': ['The Journal of Rheumatology Publishing Company Limited'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://www.jrheum.org/content/jrheum/37/12/2606.full.pdf', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5078979553', 'display_name': 'Joel D. Taurog', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': True, 'raw_author_name': 'JOEL D. TAUROG', 'raw_affiliation_strings': ['Internal Medicine'], 'affiliations': [{'raw_affiliation_string': 'Internal Medicine', 'institution_ids': []}]}], 'institution_assertions': [], 'countries_distinct_count': 0, 'institutions_distinct_count': 0, 'corresponding_author_ids': ['https://openalex.org/A5078979553'], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 3.682, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 56, 'citation_normalized_percentile': {'value': 0.999892, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 95, 'max': 96}, 'biblio': {'volume': '37', 'issue': '12', 'first_page': '2606', 'last_page': '2616'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11092', 'display_name': 'Spondyloarthritis Studies and Treatments', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/2745', 'display_name': 'Rheumatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11092', 'display_name': 'Spondyloarthritis Studies and Treatments', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/2745', 'display_name': 'Rheumatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11616', 'display_name': 'Autoimmune and Inflammatory Disorders Research', 'score': 0.9991, 'subfield': {'id': 'https://openalex.org/subfields/2720', 'display_name': 'Hematology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11020', 'display_name': 'Immune Cell Function and Interaction', 'score': 0.9985, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/hla-b27', 'display_name': 'HLA-B27', 'score': 0.7930515}, {'id': 'https://openalex.org/keywords/pathogenesis', 'display_name': 'Pathogenesis', 'score': 0.6965394}, {'id': 'https://openalex.org/keywords/spondylitis', 'display_name': 'Spondylitis', 'score': 0.44437897}], 'concepts': [{'id': 'https://openalex.org/C2777402515', 'wikidata': 'https://www.wikidata.org/wiki/Q52849', 'display_name': 'Ankylosing spondylitis', 'level': 2, 'score': 0.8169961}, {'id': 'https://openalex.org/C2778091532', 'wikidata': 'https://www.wikidata.org/wiki/Q420574', 'display_name': 'HLA-B27', 'level': 4, 'score': 0.7930515}, {'id': 'https://openalex.org/C2780942790', 'wikidata': 'https://www.wikidata.org/wiki/Q372016', 'display_name': 'Pathogenesis', 'level': 2, 'score': 0.6965394}, {'id': 'https://openalex.org/C2779343474', 'wikidata': 'https://www.wikidata.org/wiki/Q3109175', 'display_name': 'Context (archaeology)', 'level': 2, 'score': 0.6645754}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.61625993}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.5650475}, {'id': 'https://openalex.org/C2779650986', 'wikidata': 'https://www.wikidata.org/wiki/Q2165411', 'display_name': 'Spondylitis', 'level': 3, 'score': 0.44437897}, {'id': 'https://openalex.org/C188280979', 'wikidata': 'https://www.wikidata.org/wiki/Q911125', 'display_name': 'Human leukocyte antigen', 'level': 3, 'score': 0.43063974}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.20657295}, {'id': 'https://openalex.org/C147483822', 'wikidata': 'https://www.wikidata.org/wiki/Q103537', 'display_name': 'Antigen', 'level': 2, 'score': 0.12469649}, {'id': 'https://openalex.org/C151730666', 'wikidata': 'https://www.wikidata.org/wiki/Q7205', 'display_name': 'Paleontology', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D003226', 'descriptor_name': 'Congresses as Topic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D015796', 'descriptor_name': 'HLA-B27 Antigen', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D025241', 'descriptor_name': 'Spondylarthritis', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D013167', 'descriptor_name': 'Spondylitis, Ankylosing', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004195', 'descriptor_name': 'Disease Models, Animal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015796', 'descriptor_name': 'HLA-B27 Antigen', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015796', 'descriptor_name': 'HLA-B27 Antigen', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D015796', 'descriptor_name': 'HLA-B27 Antigen', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007694', 'descriptor_name': 'Killer Cells, Natural', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007694', 'descriptor_name': 'Killer Cells, Natural', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D010455', 'descriptor_name': 'Peptides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010455', 'descriptor_name': 'Peptides', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D010455', 'descriptor_name': 'Peptides', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D017510', 'descriptor_name': 'Protein Folding', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D055647', 'descriptor_name': 'Rats, Transgenic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D025241', 'descriptor_name': 'Spondylarthritis', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D025241', 'descriptor_name': 'Spondylarthritis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D025241', 'descriptor_name': 'Spondylarthritis', 'qualifier_ui': 'Q000453', 'qualifier_name': 'epidemiology', 'is_major_topic': False}, {'descriptor_ui': 'D025241', 'descriptor_name': 'Spondylarthritis', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': False}, {'descriptor_ui': 'D013167', 'descriptor_name': 'Spondylitis, Ankylosing', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013167', 'descriptor_name': 'Spondylitis, Ankylosing', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': False}, {'descriptor_ui': 'D013167', 'descriptor_name': 'Spondylitis, Ankylosing', 'qualifier_ui': 'Q000453', 'qualifier_name': 'epidemiology', 'is_major_topic': False}, {'descriptor_ui': 'D013167', 'descriptor_name': 'Spondylitis, Ankylosing', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D013601', 'descriptor_name': 'T-Lymphocytes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013601', 'descriptor_name': 'T-Lymphocytes', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D013781', 'descriptor_name': 'Texas', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D056811', 'descriptor_name': 'Unfolded Protein Response', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.3899/jrheum.100889', 'pdf_url': 'https://www.jrheum.org/content/jrheum/37/12/2606.full.pdf', 'source': {'id': 'https://openalex.org/S50602745', 'display_name': 'The Journal of Rheumatology', 'issn_l': '0315-162X', 'issn': ['0315-162X', '1499-2752'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320417', 'host_organization_name': 'The Journal of Rheumatology Publishing Company Limited', 'host_organization_lineage': ['https://openalex.org/P4310320417'], 'host_organization_lineage_names': ['The Journal of Rheumatology Publishing Company Limited'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/21123333', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3899/jrheum.100889', 'pdf_url': 'https://www.jrheum.org/content/jrheum/37/12/2606.full.pdf', 'source': {'id': 'https://openalex.org/S50602745', 'display_name': 'The Journal of Rheumatology', 'issn_l': '0315-162X', 'issn': ['0315-162X', '1499-2752'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320417', 'host_organization_name': 'The Journal of Rheumatology Publishing Company Limited', 'host_organization_lineage': ['https://openalex.org/P4310320417'], 'host_organization_lineage_names': ['The Journal of Rheumatology Publishing Company Limited'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.8}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 103, 'referenced_works': ['https://openalex.org/W1483092145', 'https://openalex.org/W1502820929', 'https://openalex.org/W1509776726', 'https://openalex.org/W1536883024', 'https://openalex.org/W1550636258', 'https://openalex.org/W1581885106', 'https://openalex.org/W1606271020', 'https://openalex.org/W166809406', 'https://openalex.org/W1669999648', 'https://openalex.org/W1811069568', 'https://openalex.org/W1899226846', 'https://openalex.org/W1920719136', 'https://openalex.org/W1945696461', 'https://openalex.org/W1971255763', 'https://openalex.org/W1971344747', 'https://openalex.org/W1973304227', 'https://openalex.org/W1974823499', 'https://openalex.org/W1976173775', 'https://openalex.org/W1978631024', 'https://openalex.org/W1981714996', 'https://openalex.org/W1981811253', 'https://openalex.org/W1983199450', 'https://openalex.org/W1985292151', 'https://openalex.org/W1989969667', 'https://openalex.org/W1990123254', 'https://openalex.org/W1996998447', 'https://openalex.org/W1998033376', 'https://openalex.org/W2002488282', 'https://openalex.org/W2002688068', 'https://openalex.org/W2003609922', 'https://openalex.org/W2012378659', 'https://openalex.org/W2013482659', 'https://openalex.org/W2019210870', 'https://openalex.org/W2026322742', 'https://openalex.org/W2027195037', 'https://openalex.org/W2028191700', 'https://openalex.org/W2028485566', 'https://openalex.org/W2032624894', 'https://openalex.org/W2032861864', 'https://openalex.org/W2034617410', 'https://openalex.org/W2034921189', 'https://openalex.org/W2036366108', 'https://openalex.org/W2040113209', 'https://openalex.org/W2041128416', 'https://openalex.org/W2042167668', 'https://openalex.org/W2043313813', 'https://openalex.org/W2046579578', 'https://openalex.org/W2047991586', 'https://openalex.org/W2054202237', 'https://openalex.org/W2058552149', 'https://openalex.org/W2058722206', 'https://openalex.org/W2067257520', 'https://openalex.org/W2067360871', 'https://openalex.org/W2069261568', 'https://openalex.org/W206978113', 'https://openalex.org/W2070684866', 'https://openalex.org/W2070778045', 'https://openalex.org/W2071893970', 'https://openalex.org/W2072245587', 'https://openalex.org/W2075739253', 'https://openalex.org/W2079139414', 'https://openalex.org/W2081187098', 'https://openalex.org/W2088644689', 'https://openalex.org/W2088672001', 'https://openalex.org/W2089198803', 'https://openalex.org/W2089693387', 'https://openalex.org/W2091378658', 'https://openalex.org/W2092404985', 'https://openalex.org/W2093456976', 'https://openalex.org/W2093944914', 'https://openalex.org/W2094084679', 'https://openalex.org/W2096309940', 'https://openalex.org/W2099078168', 'https://openalex.org/W2105152214', 'https://openalex.org/W2106319835', 'https://openalex.org/W2111256698', 'https://openalex.org/W2112092203', 'https://openalex.org/W2118434625', 'https://openalex.org/W2119006465', 'https://openalex.org/W2121211005', 'https://openalex.org/W2124537395', 'https://openalex.org/W2131371764', 'https://openalex.org/W2133705404', 'https://openalex.org/W2133842384', 'https://openalex.org/W2137781541', 'https://openalex.org/W2143886049', 'https://openalex.org/W2145651018', 'https://openalex.org/W2146173065', 'https://openalex.org/W2147396727', 'https://openalex.org/W2149566497', 'https://openalex.org/W2151878384', 'https://openalex.org/W2152057471', 'https://openalex.org/W2156374735', 'https://openalex.org/W2161707506', 'https://openalex.org/W2164763018', 'https://openalex.org/W2168521098', 'https://openalex.org/W2171666169', 'https://openalex.org/W2409112729', 'https://openalex.org/W2766535349', 'https://openalex.org/W4244626580', 'https://openalex.org/W4250753607', 'https://openalex.org/W4313333783', 'https://openalex.org/W47613842'], 'related_works': ['https://openalex.org/W44366196', 'https://openalex.org/W2745755324', 'https://openalex.org/W2466127187', 'https://openalex.org/W2415848334', 'https://openalex.org/W2385422132', 'https://openalex.org/W2340923191', 'https://openalex.org/W2132519896', 'https://openalex.org/W2129594336', 'https://openalex.org/W2068236826', 'https://openalex.org/W1512740531'], 'abstract_inverted_index': {'This': [0], 'article': [1], 'summarizes': [2], 'the': [3, 15, 20, 47, 103, 107, 117, 132, 139, 158, 176, 185, 190, 202], 'proceedings': [4], 'of': [5, 17, 22, 35, 43, 69, 91, 98, 106, 110, 119, 137, 142, 160, 181, 187, 192, 204], 'a': [6], 'one-day': [7], 'international': [8], 'workshop': [9], 'held': [10], 'in': [11, 19, 32, 116], 'July': [12], '2009': [13], 'on': [14, 157], 'role': [16], 'HLA-B27': [18, 29, 128, 133], 'pathogenesis': [21, 159, 203], 'ankylosing': [23], 'spondylitis': [24], '(AS)': [25], 'and': [26, 86, 124, 154, 173, 198], 'related': [27], 'disorders.': [28], 'is': [30, 52], 'found': [31, 148], 'about': [33, 44], '90%': [34], 'patients': [36], 'with': [37, 39, 152, 189, 196], 'AS,': [38], 'an': [40, 82], 'odds': [41], 'ratio': [42], '100,': [45], 'but': [46], 'mechanism': [48], 'underlying': [49], 'this': [50, 63], 'association': [51], 'not': [53], 'known.': [54], 'There': [55], 'are': [56], 'currently': [57], '3': [58], 'major': [59], 'mechanistic': [60], 'hypotheses': [61, 100, 113], 'for': [62, 102, 164], 'association:': [64], '(1)': [65], 'T': [66], 'cell': [67], 'recognition': [68, 90], 'one': [70], 'or': [71], 'more': [72], 'B27': [73, 77, 94, 177, 188], 'presented': [74], 'peptides;': [75], '(2)': [76], 'heavy-chain': [78, 95], 'misfolding': [79], 'that': [80, 145], 'induces': [81], 'unfolded': [83], 'protein': [84], 'response;': [85], '(3)': [87], 'innate': [88], 'immune': [89], 'cell-surface': [92], 'expressed': [93], 'dimers.': [96], 'None': [97], 'these': [99], 'accounts': [101], 'tissue': [104], 'specificity': [105], 'inflammation': [108], 'characteristic': [109], 'AS.': [111], 'These': [112], 'were': [114], 'discussed': [115], 'context': [118], 'known': [120], 'epidemiologic,': [121], 'biochemical,': [122], 'structural,': [123], 'immunologic': [125], 'differences': [126, 174], 'among': [127, 175], 'subtypes;': [129, 178], 'data': [130, 156], 'from': [131], 'transgenic': [134], 'rat': [135], 'model': [136], 'spondyloarthritis;': [138], 'growing': [140], 'list': [141], 'other': [143, 155, 193], 'genes': [144, 194], 'have': [146], 'been': [147], 'to': [149, 170], 'be': [150], 'associated': [151, 195], 'AS;': [153, 197], 'spondyloarthritis.': [161, 205], 'Proposed': [162], 'directions': [163], 'future': [165], 'research': [166], 'include': [167], 'expanded': [168], 'efforts': [169], 'define': [171], 'similarities': [172], 'further': [179], 'development': [180], 'animal': [182], 'models;': [183], 'identifying': [184], 'interactions': [186], 'products': [191], 'continued': [199], 'investigation': [200], 'into': [201]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1991903436', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 3}, {'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 4}, {'year': 2020, 'cited_by_count': 4}, {'year': 2019, 'cited_by_count': 3}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 3}, {'year': 2016, 'cited_by_count': 4}, {'year': 2015, 'cited_by_count': 9}, {'year': 2014, 'cited_by_count': 6}, {'year': 2013, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 4}], 'updated_date': '2024-12-17T11:49:29.286655', 'created_date': '2016-06-24'}