Title: Association of HLA‑B27 and its subtypes with ankylosing spondylitis and clinical manifestations of ankylosing spondylitis in different HLA-B27 subtypes: comment on the article by Lin et al.
Abstract: and ethnicities.Therefore, the results of this analysis should not be generalized to all patients with AS.Clinical features of patients with AS with different HLA-B27 subtypes are suggested to be reviewed and meta-analyzed separately in various races and parts of the world.Research reviews on different races and regions of the world individually (like Europe, Middle East, Far East, and Africa) may help to exploring more exactly the association between symptoms and HLA-B27 subtypes in AS disease. Compliance with ethical standards