Publication Information

{'id': 'https://openalex.org/W1986203111', 'doi': 'https://doi.org/10.1161/01.cir.37.4s2.ii-154', 'title': 'Reduced Protamine Dosage for Heparin Neutralization in Open-Heart Operations', 'display_name': 'Reduced Protamine Dosage for Heparin Neutralization in Open-Heart Operations', 'publication_year': 1968, 'publication_date': '1968-04-01', 'ids': {'openalex': 'https://openalex.org/W1986203111', 'doi': 'https://doi.org/10.1161/01.cir.37.4s2.ii-154', 'mag': '1986203111', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/5646575'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1161/01.cir.37.4s2.ii-154', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S116251202', 'display_name': 'Circulation', 'issn_l': '0009-7322', 'issn': ['0009-7322', '1524-4539'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5063026944', 'display_name': 'Robert L. Berger', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I121934306', 'display_name': 'Tufts University', 'ror': 'https://ror.org/05wvpxv85', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I121934306']}, {'id': 'https://openalex.org/I3018163063', 'display_name': "St. Elizabeth's Medical Center", 'ror': 'https://ror.org/00cr15z55', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I3018163063']}, {'id': 'https://openalex.org/I2802104953', 'display_name': 'St. Elizabeths Hospital', 'ror': 'https://ror.org/022w03s59', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802104953']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'ROBERT L. BERGER', 'raw_affiliation_strings': ["From the Departments of Medicine and Surgery, St. Elizabeth's Hospital and Tufts University School of Medicine, Boston, Massachusetts."], 'affiliations': [{'raw_affiliation_string': "From the Departments of Medicine and Surgery, St. Elizabeth's Hospital and Tufts University School of Medicine, Boston, Massachusetts.", 'institution_ids': ['https://openalex.org/I121934306', 'https://openalex.org/I3018163063', 'https://openalex.org/I2802104953']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5113614802', 'display_name': 'Krishnaswamy Ramaswamy', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I121934306', 'display_name': 'Tufts University', 'ror': 'https://ror.org/05wvpxv85', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I121934306']}, {'id': 'https://openalex.org/I3018163063', 'display_name': "St. Elizabeth's Medical Center", 'ror': 'https://ror.org/00cr15z55', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I3018163063']}, {'id': 'https://openalex.org/I2802104953', 'display_name': 'St. Elizabeths Hospital', 'ror': 'https://ror.org/022w03s59', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802104953']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'KRISHNASWAMY RAMASWAMY', 'raw_affiliation_strings': ["From the Departments of Medicine and Surgery, St. Elizabeth's Hospital and Tufts University School of Medicine, Boston, Massachusetts."], 'affiliations': [{'raw_affiliation_string': "From the Departments of Medicine and Surgery, St. Elizabeth's Hospital and Tufts University School of Medicine, Boston, Massachusetts.", 'institution_ids': ['https://openalex.org/I121934306', 'https://openalex.org/I3018163063', 'https://openalex.org/I2802104953']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5103535389', 'display_name': 'Thomas J. Ryan', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I121934306', 'display_name': 'Tufts University', 'ror': 'https://ror.org/05wvpxv85', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I121934306']}, {'id': 'https://openalex.org/I3018163063', 'display_name': "St. Elizabeth's Medical Center", 'ror': 'https://ror.org/00cr15z55', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I3018163063']}, {'id': 'https://openalex.org/I2802104953', 'display_name': 'St. Elizabeths Hospital', 'ror': 'https://ror.org/022w03s59', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802104953']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'THOMAS J. RYAN', 'raw_affiliation_strings': ["From the Departments of Medicine and Surgery, St. Elizabeth's Hospital and Tufts University School of Medicine, Boston, Massachusetts."], 'affiliations': [{'raw_affiliation_string': "From the Departments of Medicine and Surgery, St. Elizabeth's Hospital and Tufts University School of Medicine, Boston, Massachusetts.", 'institution_ids': ['https://openalex.org/I121934306', 'https://openalex.org/I3018163063', 'https://openalex.org/I2802104953']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 1.959, 'has_fulltext': False, 'cited_by_count': 32, 'citation_normalized_percentile': {'value': 0.935261, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 93, 'max': 94}, 'biblio': {'volume': '37', 'issue': '4s2', 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12352', 'display_name': 'Heparin-Induced Thrombocytopenia and Thrombosis', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12352', 'display_name': 'Heparin-Induced Thrombocytopenia and Thrombosis', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10285', 'display_name': 'Venous Thromboembolism Diagnosis and Management', 'score': 0.9987, 'subfield': {'id': 'https://openalex.org/subfields/2724', 'display_name': 'Internal Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10065', 'display_name': 'Atrial Fibrillation Management and Outcomes', 'score': 0.9984, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C2780835560', 'wikidata': 'https://www.wikidata.org/wiki/Q5449573', 'display_name': 'Protamine', 'level': 3, 'score': 0.9158301}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.90583146}, {'id': 'https://openalex.org/C2777557582', 'wikidata': 'https://www.wikidata.org/wiki/Q190016', 'display_name': 'Heparin', 'level': 2, 'score': 0.87320143}, {'id': 'https://openalex.org/C14086860', 'wikidata': 'https://www.wikidata.org/wiki/Q337120', 'display_name': 'Neutralization', 'level': 3, 'score': 0.7603421}, {'id': 'https://openalex.org/C42219234', 'wikidata': 'https://www.wikidata.org/wiki/Q131130', 'display_name': 'Anesthesia', 'level': 1, 'score': 0.52897894}, {'id': 'https://openalex.org/C141071460', 'wikidata': 'https://www.wikidata.org/wiki/Q40821', 'display_name': 'Surgery', 'level': 1, 'score': 0.31630307}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.12678197}, {'id': 'https://openalex.org/C159654299', 'wikidata': 'https://www.wikidata.org/wiki/Q79460', 'display_name': 'Antibody', 'level': 2, 'score': 0.1235269}], 'mesh': [{'descriptor_ui': 'D006348', 'descriptor_name': 'Cardiac Surgical Procedures', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D006494', 'descriptor_name': 'Heparin Antagonists', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D011479', 'descriptor_name': 'Protamines', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': True}, {'descriptor_ui': 'D006470', 'descriptor_name': 'Hemorrhage', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006470', 'descriptor_name': 'Hemorrhage', 'qualifier_ui': 'Q000209', 'qualifier_name': 'etiology', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011183', 'descriptor_name': 'Postoperative Complications', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011479', 'descriptor_name': 'Protamines', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1161/01.cir.37.4s2.ii-154', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S116251202', 'display_name': 'Circulation', 'issn_l': '0009-7322', 'issn': ['0009-7322', '1524-4539'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/5646575', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.63}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W4386743610', 'https://openalex.org/W4323284267', 'https://openalex.org/W2411561722', 'https://openalex.org/W2365147984', 'https://openalex.org/W2027795091', 'https://openalex.org/W2025062353', 'https://openalex.org/W2023619243', 'https://openalex.org/W1980832026', 'https://openalex.org/W174166667', 'https://openalex.org/W173534854'], 'abstract_inverted_index': {'Two': [0], 'comparable': [1], 'groups': [2], 'of': [3, 12, 16, 21, 41, 51], 'open-heart': [4], 'patients': [5], 'were': [6], 'given': [7], '0.79': [8], 'and': [9, 47], '1.37': [10], 'mg': [11], 'protamine': [13, 22, 32], 'for': [14, 54], 'neutralization': [15, 40], 'exogenous': [17], 'heparin.': [18], 'The': [19, 30], 'influence': [20], 'dosage': [23, 33], 'on': [24], 'postoperative': [25, 44], 'bleeding': [26], 'was': [27, 34], 'then': [28], 'evaluated.': [29], 'lower': [31], 'associated': [35], 'with': [36], 'a': [37, 48], 'more': [38], 'rapid': [39], 'heparin,': [42], 'reduced': [43, 49], 'blood': [45], 'loss,': [46], 'incidence': [50], 'exploratory': [52], 'thoracotomy': [53], 'excessive': [55], 'bleeding.': [56]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1986203111', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 2}, {'year': 2013, 'cited_by_count': 2}], 'updated_date': '2024-12-14T06:34:56.085980', 'created_date': '2016-06-24'}