Heparin rebound: A comparative study of protamine chloride and protamine sulfate in patients undergoing coronary artery bypass surgery

Name: Work Video:
Duration: 3 min 30 s
Anne Kuitunen; Markku Salmenperä; Jussi S. Heinonen; Vesa Rasi; G. Myllylä
{'id': 'https://openalex.org/W1980832026', 'doi': 'https://doi.org/10.1016/1053-0770(91)90278-2', 'title': 'Heparin rebound: A comparative study of protamine chloride and protamine sulfate in patients undergoing coronary artery bypass surgery', 'display_name': 'Heparin rebound: A comparative study of protamine chloride and protamine sulfate in patients undergoing coronary artery bypass surgery', 'publication_year': 1991, 'publication_date': '1991-06-01', 'ids': {'openalex': 'https://openalex.org/W1980832026', 'doi': 'https://doi.org/10.1016/1053-0770(91)90278-2', 'mag': '1980832026', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/1863741'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/1053-0770(91)90278-2', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S132356188', 'display_name': 'Journal of Cardiothoracic and Vascular Anesthesia', 'issn_l': '1053-0770', 'issn': ['1053-0770', '1532-8422'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5052605844', 'display_name': 'Anne Kuitunen', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2800394112', 'display_name': 'Helsinki University Hospital', 'ror': 'https://ror.org/02e8hzf44', 'country_code': 'FI', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800394112', 'https://openalex.org/I4210166427']}], 'countries': ['FI'], 'is_corresponding': False, 'raw_author_name': 'Anne H. Kuitunen', 'raw_affiliation_strings': ['Department of Anesthesiology, Helsinki University Central Hospital, Finland'], 'affiliations': [{'raw_affiliation_string': 'Department of Anesthesiology, Helsinki University Central Hospital, Finland', 'institution_ids': ['https://openalex.org/I2800394112']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5056575891', 'display_name': 'Markku Salmenperä', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2801434414', 'display_name': 'Finnish Red Cross', 'ror': 'https://ror.org/045thge14', 'country_code': 'FI', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I2801434414']}], 'countries': ['FI'], 'is_corresponding': False, 'raw_author_name': 'Markku T. Salmenperä', 'raw_affiliation_strings': ['Department of Anesthesiology, Helsinki University Central Hospital, and Finnish Red Cross Blood Transfusion Service, Helsinki, Finland'], 'affiliations': [{'raw_affiliation_string': 'Department of Anesthesiology, Helsinki University Central Hospital, and Finnish Red Cross Blood Transfusion Service, Helsinki, Finland', 'institution_ids': ['https://openalex.org/I2801434414']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5021581947', 'display_name': 'Jussi S. Heinonen', 'orcid': 'https://orcid.org/0000-0001-8998-4357'}, 'institutions': [{'id': 'https://openalex.org/I2801434414', 'display_name': 'Finnish Red Cross', 'ror': 'https://ror.org/045thge14', 'country_code': 'FI', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I2801434414']}], 'countries': ['FI'], 'is_corresponding': False, 'raw_author_name': 'Jussi Heinonen', 'raw_affiliation_strings': ['Department of Anesthesiology, Helsinki University Central Hospital, and Finnish Red Cross Blood Transfusion Service, Helsinki, Finland'], 'affiliations': [{'raw_affiliation_string': 'Department of Anesthesiology, Helsinki University Central Hospital, and Finnish Red Cross Blood Transfusion Service, Helsinki, Finland', 'institution_ids': ['https://openalex.org/I2801434414']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5107447003', 'display_name': 'Vesa Rasi', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2801434414', 'display_name': 'Finnish Red Cross', 'ror': 'https://ror.org/045thge14', 'country_code': 'FI', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I2801434414']}], 'countries': ['FI'], 'is_corresponding': False, 'raw_author_name': 'Vesa P. Rasi', 'raw_affiliation_strings': ['Department of Anesthesiology, Helsinki University Central Hospital, and Finnish Red Cross Blood Transfusion Service, Helsinki, Finland'], 'affiliations': [{'raw_affiliation_string': 'Department of Anesthesiology, Helsinki University Central Hospital, and Finnish Red Cross Blood Transfusion Service, Helsinki, Finland', 'institution_ids': ['https://openalex.org/I2801434414']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5072050136', 'display_name': 'G. Myllylä', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2801434414', 'display_name': 'Finnish Red Cross', 'ror': 'https://ror.org/045thge14', 'country_code': 'FI', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I2801434414']}], 'countries': ['FI'], 'is_corresponding': False, 'raw_author_name': 'Gunnar Myllylä', 'raw_affiliation_strings': ['Department of Anesthesiology, Helsinki University Central Hospital, and Finnish Red Cross Blood Transfusion Service, Helsinki, Finland'], 'affiliations': [{'raw_affiliation_string': 'Department of Anesthesiology, Helsinki University Central Hospital, and Finnish Red Cross Blood Transfusion Service, Helsinki, Finland', 'institution_ids': ['https://openalex.org/I2801434414']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3070, 'currency': 'USD', 'value_usd': 3070, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.473, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 24, 'citation_normalized_percentile': {'value': 0.852751, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 86, 'max': 87}, 'biblio': {'volume': '5', 'issue': '3', 'first_page': '221', 'last_page': '226'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11055', 'display_name': 'Cardiac and Coronary Surgery Techniques', 'score': 0.9989, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11055', 'display_name': 'Cardiac and Coronary Surgery Techniques', 'score': 0.9989, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11064', 'display_name': 'Antiplatelet Therapy and Cardiovascular Diseases', 'score': 0.9989, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10172', 'display_name': 'Cardiac Valve Diseases and Treatments', 'score': 0.9894, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/protamine-sulfate', 'display_name': 'Protamine sulfate', 'score': 0.96226466}], 'concepts': [{'id': 'https://openalex.org/C2779354726', 'wikidata': 'https://www.wikidata.org/wiki/Q22075855', 'display_name': 'Protamine sulfate', 'level': 4, 'score': 0.96226466}, {'id': 'https://openalex.org/C2780835560', 'wikidata': 'https://www.wikidata.org/wiki/Q5449573', 'display_name': 'Protamine', 'level': 3, 'score': 0.9544967}, {'id': 'https://openalex.org/C2777557582', 'wikidata': 'https://www.wikidata.org/wiki/Q190016', 'display_name': 'Heparin', 'level': 2, 'score': 0.95345205}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.78045243}, {'id': 'https://openalex.org/C2778382381', 'wikidata': 'https://www.wikidata.org/wiki/Q179217', 'display_name': 'Coagulation', 'level': 2, 'score': 0.6129097}, {'id': 'https://openalex.org/C42219234', 'wikidata': 'https://www.wikidata.org/wiki/Q131130', 'display_name': 'Anesthesia', 'level': 1, 'score': 0.47655112}, {'id': 'https://openalex.org/C2778205648', 'wikidata': 'https://www.wikidata.org/wiki/Q215118', 'display_name': 'Anticoagulant', 'level': 2, 'score': 0.4420665}, {'id': 'https://openalex.org/C2775901492', 'wikidata': 'https://www.wikidata.org/wiki/Q186020', 'display_name': 'Coronary artery bypass surgery', 'level': 3, 'score': 0.44024104}, {'id': 'https://openalex.org/C2776820930', 'wikidata': 'https://www.wikidata.org/wiki/Q9655', 'display_name': 'Artery', 'level': 2, 'score': 0.37507567}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.37391937}], 'mesh': [{'descriptor_ui': 'D001778', 'descriptor_name': 'Blood Coagulation Disorders', 'qualifier_ui': 'Q000517', 'qualifier_name': 'prevention & control', 'is_major_topic': True}, {'descriptor_ui': 'D001026', 'descriptor_name': 'Coronary Artery Bypass', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D006493', 'descriptor_name': 'Heparin', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': True}, {'descriptor_ui': 'D011479', 'descriptor_name': 'Protamines', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D001777', 'descriptor_name': 'Blood Coagulation', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D001777', 'descriptor_name': 'Blood Coagulation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001778', 'descriptor_name': 'Blood Coagulation Disorders', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016063', 'descriptor_name': 'Blood Loss, Surgical', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004305', 'descriptor_name': 'Dose-Response Relationship, Drug', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004311', 'descriptor_name': 'Double-Blind Method', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006324', 'descriptor_name': 'Heart Arrest, Induced', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006493', 'descriptor_name': 'Heparin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006493', 'descriptor_name': 'Heparin', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011479', 'descriptor_name': 'Protamines', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D011479', 'descriptor_name': 'Protamines', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013997', 'descriptor_name': 'Time Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/1053-0770(91)90278-2', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S132356188', 'display_name': 'Journal of Cardiothoracic and Vascular Anesthesia', 'issn_l': '1053-0770', 'issn': ['1053-0770', '1532-8422'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/1863741', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.73, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 43, 'referenced_works': ['https://openalex.org/W12602005', 'https://openalex.org/W140499992', 'https://openalex.org/W1451026943', 'https://openalex.org/W1968015423', 'https://openalex.org/W1991865846', 'https://openalex.org/W1993155965', 'https://openalex.org/W2000873042', 'https://openalex.org/W2003963773', 'https://openalex.org/W2009685338', 'https://openalex.org/W2009685550', 'https://openalex.org/W2015057125', 'https://openalex.org/W2017241209', 'https://openalex.org/W2018142151', 'https://openalex.org/W2019372838', 'https://openalex.org/W2026235236', 'https://openalex.org/W2034991772', 'https://openalex.org/W2039017397', 'https://openalex.org/W2042009806', 'https://openalex.org/W2046977249', 'https://openalex.org/W2066401415', 'https://openalex.org/W2093413758', 'https://openalex.org/W2136807780', 'https://openalex.org/W2151844165', 'https://openalex.org/W2300878826', 'https://openalex.org/W2327743808', 'https://openalex.org/W2399495832', 'https://openalex.org/W2409032991', 'https://openalex.org/W2409099665', 'https://openalex.org/W2409408932', 'https://openalex.org/W2414546136', 'https://openalex.org/W2416007221', 'https://openalex.org/W2416247004', 'https://openalex.org/W2435201274', 'https://openalex.org/W2436500472', 'https://openalex.org/W2464149329', 'https://openalex.org/W2766496402', 'https://openalex.org/W32418578', 'https://openalex.org/W4285719527', 'https://openalex.org/W4320573533', 'https://openalex.org/W4323284267', 'https://openalex.org/W4323874325', 'https://openalex.org/W4386383652', 'https://openalex.org/W79268717'], 'related_works': ['https://openalex.org/W2462737584', 'https://openalex.org/W2415002397', 'https://openalex.org/W2411036744', 'https://openalex.org/W2328522296', 'https://openalex.org/W2111990318', 'https://openalex.org/W2027795091', 'https://openalex.org/W2025062353', 'https://openalex.org/W2023619243', 'https://openalex.org/W1980832026', 'https://openalex.org/W1964253022'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1980832026', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2024-12-16T03:59:59.034531', 'created_date': '2016-06-24'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
