Publication Information

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462, 510, 644, 646, 654, 743, 753, 837, 915, 970, 977, 1162, 1219, 1261, 1264, 1284, 1427, 1471, 1498, 1634, 1639, 1778, 1988, 1997, 2065, 2198, 2216, 2335, 2444, 2446, 2577, 2637, 2685, 2690, 2717, 2760, 2772, 2777, 2852, 2904, 2944, 2954, 2981, 3012, 3018, 3024, 3050, 3059, 3081, 3108, 3114, 3274, 3321, 3356, 3499, 3506, 3518, 3547, 3564, 3643, 3847, 3963, 3975], 'interferon-γ': [15, 252], '(IFN-γ)': [16, 253], 'are': [17, 254, 745, 1217, 1252, 1277, 1289, 1460, 1476, 2028, 2347, 2363], 'preeminent.': [18, 255], 'These': [19, 165, 256, 402, 2559], 'two': [20, 84, 257, 321, 699, 2345], 'cytokines': [21, 212, 258, 449, 2346, 3752, 4222], 'exert': [22, 259, 2337], 'antagonistic': [23, 87, 196, 260, 324, 433, 2358, 2471, 2537, 2605], 'effects': [24, 215, 261, 452, 530, 2339, 2505, 4225], 'on': [25, 216, 262, 453, 2340, 2508, 2544, 2877, 3883, 4164], 'fibroblasts,': [26, 47, 146, 263, 284, 383, 2576], 'play': [28, 265], 'important': [29, 266, 2102, 2604], 'roles': [30, 267, 640, 1993], 'in': [31, 44, 101, 132, 147, 203, 268, 281, 338, 369, 384, 440, 538, 641, 666, 959, 1034, 1046, 1059, 1106, 1114, 1156, 1255, 1462, 1486, 1930, 1973, 1977, 1994, 2025, 2105, 2210, 2370, 2394, 2420, 2450, 2495, 2531, 2550, 2575, 2582, 2585, 2698, 2703, 2804, 2916, 3026, 3052, 3126, 3134, 3478, 3504, 3742, 3748, 3755, 3804, 3817, 3871, 3938, 3995, 4001, 4106, 4113], 'physiologic': [33, 270, 647], 'regulation': [34, 89, 204, 271, 326, 441, 1293, 2107, 2606, 3658, 3700], 'matrix': [37, 274, 505], 'turnover.': [38, 275], 'We': [39, 92, 276, 329, 1038, 1920, 2197], 'have': [40, 277, 1039, 2194, 2200, 3987], 'shown': [41, 278, 1040, 2201, 4072], 'previously': [42, 279, 1041, 1921, 2202, 2653, 3444, 3603, 3988], 'normal': [45, 282, 2496, 3662], 'skin': [46, 283, 1048, 2497, 3663], 'TGF-β': [48, 131, 285, 368, 637, 662, 694, 710, 720, 750, 968, 1036, 1112, 1164, 1227, 1965, 2222, 2334, 2474, 2507, 2529, 2543, 2638, 2795, 3034, 3523, 3672, 3996, 4078, 4183], 'positively': [49, 182, 286, 419, 2568], 'regulates': [50, 287, 491], 'α2(I)': [51, 288], 'procollagen': [52, 289], 'gene': [53, 290, 1975, 2076, 2512, 2573, 2609, 2729, 3168, 3387], '(COL1A2)': [54, 291, 2513], 'promoter': [55, 292, 1057, 1119, 3164, 3382, 3419, 3711, 3735, 3756, 3858, 3885, 4110], 'activity': [56, 293, 663, 1058, 1582, 3678, 3717, 3757, 3886, 4107], 'through': [57, 294, 494, 698, 2030, 2519, 2536], 'cellular': [59, 123, 223, 296, 360, 460, 492, 696, 1035, 1644, 1958, 4209], 'Smad': [60, 105, 199, 297, 342, 436, 815, 845, 1775, 4035], 'signal': [61, 298, 1488, 4036], 'transduction': [62, 299, 1489, 4037], 'pathway.': [63, 300], 'In': [64, 143, 208, 301, 380, 445, 2173, 2481, 2785], 'contrast,': [65, 302], 'IFN-γ': [66, 96, 107, 159, 303, 333, 344, 396, 2024, 2178, 2204, 2336, 2386, 2477, 2494, 2518, 2554, 2628, 2773, 2797, 3032, 3060, 3149, 3519, 3730, 3770, 3774, 3786, 3809, 3882, 3931, 3944, 4047, 4160, 4181, 4214], 'activates': [67, 304], 'Stat1α,': [68, 176, 305, 413], 'down-regulates': [69, 306], 'COL1A2transcription,': [70, 307], 'abrogates': [72, 97, 309, 334, 2217, 2387], 'its': [73, 310, 916, 1017, 2095, 2218], 'stimulation': [74, 129, 311, 366, 541, 2050, 2219, 2382, 3675, 3997, 4184], 'induced': [75, 312, 1021, 1225, 2022, 2220, 3721, 3775], 'by': [76, 103, 130, 313, 340, 367, 540, 1022, 1092, 1226, 1494, 1509, 1985, 2023, 2051, 2221, 2349, 2476, 2493, 2517, 2555, 2591, 2611, 2652, 2859, 2875, 2914, 3003, 3014, 3037, 3094, 3118, 3130, 3431, 3484, 3639, 3649, 3680, 3692, 3722, 3930, 3968, 4189], 'TGF-β.': [77, 314, 3065], 'The': [78, 187, 315, 424, 1117, 1580, 1606, 2468, 2499, 2539, 2596, 2720, 2870, 2997, 3016, 3473, 3583, 3716, 4103], 'level': [79, 316], 'integration': [81, 318], 'pathways': [85, 202, 322, 439, 1646], 'mediating': [86, 323], 'collagen': [88, 217, 325, 454, 548, 1974, 2209, 2341, 2361, 2384, 2491, 2511, 2572, 2608, 2969, 3660, 3747, 3763], 'is': [90, 327, 533, 664, 1019, 1271, 1585, 2478], 'unknown.': [91, 328], 'now': [93, 330], 'report': [94, 331], 'TGF-β-stimulated': [98, 335, 1927, 2490], 'COL1A2': [99, 336, 1118, 1928, 2545, 3163, 3201, 3669, 3685, 3702, 3857, 3884, 3999, 4069, 4186], 'transcription': [100, 230, 337, 467, 497, 511, 544, 1464, 1493, 1574, 1621, 1929, 1976, 2184, 2207, 2492, 2514, 2546, 2574, 2610, 4000, 4187], 'fibroblasts': [102, 209, 339, 446, 1049, 1931, 2211, 2532, 2587, 3043, 3133, 3664, 3812, 4002, 4115], 'inhibiting': [104, 341], 'activities.': [106, 343, 4218], 'appears': [108, 345, 1026], 'to': [109, 145, 155, 161, 193, 211, 346, 382, 392, 398, 430, 448, 961, 967, 1027, 1221, 1269, 1279, 1281, 1576, 1614, 1625, 2068, 2175, 2365, 2946, 3148, 3157, 3166, 3384, 3421, 3526, 3542, 3577, 3750, 3772, 3860, 3873, 4073, 4076], 'induce': [110, 347], 'competition': [111, 348], 'between': [112, 349, 2687, 3634], 'activated': [113, 350, 709, 1111, 1952, 2583], 'Stat1α': [114, 351, 2055, 2078, 2089, 2584, 3025, 3919, 4196], 'Smad3': [116, 174, 353, 411, 744, 925, 978, 1045, 1953, 3293, 3994, 4166], 'for': [117, 172, 195, 354, 409, 432, 1291, 1954, 2882, 2922, 2991, 3090, 3271, 3698, 3733, 3813, 3926, 3945, 3961, 3993, 4042], 'interaction': [118, 197, 227, 355, 434, 464, 2099], 'with': [119, 213, 228, 356, 450, 465, 715, 755, 847, 972, 1320, 1588, 1616, 1771, 1951, 2092, 2708, 2840, 2885, 2900, 2948, 3005, 3054, 3074, 3077, 3494, 3508, 3513, 3522, 3668, 3769, 3943, 4125, 4223], 'limiting': [120, 357, 1955], 'amounts': [121, 358, 1956], 'p300/CBP.': [124, 361], 'Overexpression': [125, 362], 'p300': [127, 364, 1475, 1780, 1924], 'restoredCOL1A2': [128, 365], 'presence': [134, 371, 1607, 2552, 3028, 3863], 'IFN-γ,': [136, 373, 2052, 3693, 3723], 'potentiated': [138, 375], 'IFN-γ-dependent': [139, 376], 'positive': [140, 377, 2106], 'transcriptional': [141, 378, 829, 1223, 1292, 1501, 1581, 2087, 2110, 2176, 3146, 3787, 3876, 4217], 'responses.': [142, 379, 2088], 'contrast': [144, 381, 960, 3872], 'U4A': [148, 385], 'cells': [149, 386, 1987, 2027, 2351, 2396, 2423, 2452, 2897, 3070, 3958], 'lacking': [150, 387], 'Jak1': [151, 388], 'consequently': [153, 390], 'unable': [154, 391], 'activate': [156, 393], 'Stat1α-mediated': [157, 394], 'responses,': [158, 395, 2390, 3877], 'failed': [160, 397, 3859], 'repress': [162, 399], 'TGF-β-induced': [163, 400, 4104], 'transcription.': [164, 186, 401, 423], 'results': [166, 403, 2500, 4122], 'indicate': [167, 404, 2501, 2561], 'as': [169, 406, 828, 1483, 2081, 2379, 3137, 3442, 3490, 3601, 3802, 3971], 'essential': [170, 407, 1484, 2083, 3783], 'coactivators': [171, 408, 1485, 1519], 'both': [173, 410, 1995], 'nuclear': [177, 414, 1275, 3140, 3537, 3778], 'p300/CBP': [178, 415, 1491, 1613, 1641, 1772, 1972, 2093, 2563], 'integrate': [179, 416, 1642, 2564], 'or': [183, 420, 2569, 2710, 2802, 2919, 3029, 3033, 3120, 3141, 3150, 3435, 3521, 3948, 4167, 4170, 4205], 'negatively': [184, 421, 2181, 2570], 'regulateCOL1A2': [185, 422], 'findings': [188, 425, 2560, 2597, 4178], 'implicate': [189, 426], 'a': [190, 427, 904, 1981, 2520, 2699, 2763, 3127, 3578, 3821, 3990, 4040, 4128], 'novel': [191, 428, 2599], 'mechanism': [192, 429], 'account': [194, 431], 'Jak-Stat': [201, 438, 2032], 'target': [206, 443, 1577, 2075, 4041], 'genes.': [207, 444, 1467], 'responding': [210, 447], 'opposing': [214, 451, 4224], 'transcription,': [218, 455, 2385, 3661], 'relative': [220, 457, 2853], 'levels': [221, 458, 2854], 'coactivators,': [224, 461], 'their': [226, 463, 1512, 1589, 2357, 4216], 'regulated': [229, 466, 1620], 'factors,': [231, 468], 'may': [232, 469], 'govern': [233, 470], 'net': [235, 472], 'effect.': [236, 473], 'CREB-binding': [477, 1468], 'protein': [478, 1469, 1474, 3509, 3565, 4171], 'interferon': [479], 'γ-activated': [480, 2070], 'sites': [481, 2071, 2353], 'base': [482], 'pair(s)': [483], 'chloramphenicol': [484], 'acetyltransferase': [485, 1515], 'Smad-binding': [486, 2522, 3235, 3580, 4070], 'element': [487, 2523, 3581], 'Transforming': [488, 2769], 'responses': [493, 1224, 2000, 2021, 2111, 3147, 3788, 4079], 'modulation': [495, 2472], 'genes': [499, 549, 1166, 1584], 'encoding': [500], 'cell': [501, 2645, 2722, 2800, 2906], 'cycle': [502], 'regulators,': [503], 'proteins,': [506], 'adhesion': [507], 'molecules,': [508], 'cytokines,': [509, 3497], 'factors': [512, 1276, 1497, 1575], '(1Kingsley': [513], 'D.M.': [514, 1732], 'Genes': [515, 1397, 1793, 1811], 'Dev.': [516, 1398, 1794, 1812], '1994;': [517, 585, 603, 686, 2041], '8:': [518], '133-146Crossref': [519], 'PubMed': [520, 565, 591, 609, 631, 689, 737, 772, 789, 808, 871, 897, 953, 1011, 1084, 1149, 1185, 1211, 1244, 1314, 1338, 1354, 1383, 1402, 1422, 1455, 1535, 1559, 1601, 1663, 1684, 1714, 1737, 1762, 1798, 1816, 1839, 1863, 1885, 1915, 1944, 2015, 2044, 2140, 2168, 2239, 2263, 2285, 2305, 2328, 2413, 2439, 2680, 2755, 2831, 3186, 3220, 3262, 3288, 3316, 3351, 3468, 3559, 3627, 3842, 3909, 4026, 4096, 4155], 'Scopus': [521, 632, 690, 738, 773, 790, 809, 872, 898, 954, 1012, 1085, 1150, 1186, 1212, 1245, 1315, 1339, 1355, 1384, 1403, 1423, 1456, 1536, 1560, 1602, 1664, 1685, 1715, 1738, 1763, 1799, 1817, 1840, 1864, 1886, 1916, 1945, 2016, 2045, 2141, 2169, 2240, 2286, 2306, 2329, 2414, 2440, 2681, 2756, 2832, 3187, 3221, 3263, 3289, 3317, 3352, 3469, 3560, 3628, 3843, 3910, 4027, 4097, 4156], '(1731)': [522], 'Google': [523, 566, 592, 610, 634, 692, 740, 775, 792, 811, 874, 900, 956, 1014, 1087, 1152, 1188, 1214, 1247, 1317, 1341, 1357, 1386, 1405, 1425, 1458, 1538, 1562, 1604, 1666, 1687, 1703, 1717, 1740, 1765, 1801, 1819, 1842, 1866, 1888, 1918, 1947, 2018, 2047, 2143, 2171, 2242, 2264, 2288, 2308, 2331, 2416, 2442, 2466, 2683, 2758, 2834, 3189, 3223, 3265, 3291, 3319, 3354, 3471, 3562, 3630, 3845, 3912, 4029, 4099, 4158], 'Scholar).': [524, 635, 693, 741, 812, 901, 957, 1015, 1088, 1248, 1318, 1563, 1605, 1766, 1919, 1948, 2019, 2048, 2172, 2332, 2467, 2835, 3472, 3631, 3913, 4159], 'One': [525], 'most': [528, 2026], 'potent': [529], 'TGF-β1': [532], 'connective': [534, 648, 2374], 'tissue': [535, 649, 655, 676, 2355, 2375, 2614], 'accumulation,': [536], 'achieved': [537], 'part': [539], 'type': [546, 3273], 'I': [547, 2510, 2968], '(2Ignotz': [550], 'R.A.': [551, 3303], 'Endo': [552], 'T.': [553, 933, 1444, 1530, 1692, 1698, 1708, 1751, 1757, 1792, 1901, 2004, 2267, 2313, 3831, 3894], 'Massague': [554, 766, 884, 1872], 'J.': [555, 556, 571, 579, 581, 582, 600, 617, 620, 684, 767, 885, 986, 1072, 1073, 1181, 1200, 1237, 1238, 1432, 1710, 1851, 1873, 1874, 1939, 2232, 2233, 2245, 2249, 2253, 2257, 2275, 2276, 2297, 2321, 2322, 2428, 2458, 2460, 2461, 2668, 2669, 2734, 2819, 2820, 3175, 3216, 3277, 3366, 3396, 3456, 3457, 3615, 3616, 3835, 3836, 3902, 3903, 4014, 4015, 4089, 4090], 'Biol.': [557, 583, 601, 621, 804, 1201, 1834, 1875, 2301, 2429, 3176], 'Chem.': [558, 584, 602, 622, 1202, 1876, 2430, 3177], '1987;': [559], '262:': [560], '6443-6446Abstract': [561], 'Full': [562, 588, 606, 626, 628, 732, 734, 866, 868, 892, 894, 1006, 1008, 1079, 1081, 1144, 1146, 1206, 1208, 1554, 1556, 1880, 1882, 2282, 2434, 2436, 2675, 2677, 2826, 2828, 3181, 3183, 3257, 3259, 3463, 3465, 3622, 3624, 4021, 4023, 4150, 4152], 'Text': [563, 589, 607, 627, 629, 733, 735, 867, 869, 893, 895, 1007, 1009, 1080, 1082, 1145, 1147, 1207, 1209, 1555, 1557, 1881, 1883, 2283, 2435, 2437, 2676, 2678, 2827, 2829, 3182, 3184, 3258, 3260, 3464, 3466, 3623, 3625, 4022, 4024, 4151, 4153], 'PDF': [564, 590, 608, 630, 736, 870, 896, 1010, 1083, 1148, 1210, 1558, 1884, 2284, 2438, 2679, 2830, 3185, 3261, 3467, 3626, 4025, 4154], 'Scholar,': [567, 593, 611, 776, 793, 875, 1189, 1358, 1539, 1667, 1688, 1704, 1718, 1741, 1802, 1820, 1843, 1867, 1889, 2144, 2243, 2265, 2289, 2309], '3Jimenez': [568], 'S.A.': [569, 2255], 'Varga': [570, 1071, 1236, 1938, 2274, 2320, 2667, 2818, 3455, 3614, 3834, 3901, 4013, 4088], 'Olsen': [572, 2246], 'A.': [573, 577, 615, 619, 763, 765, 927, 931, 1068, 1310, 1379, 1409, 1418, 1730, 1845, 1911, 2136, 2164, 2247, 2299, 2664, 2740, 2815, 3312, 3328, 3452, 3611, 3829, 4010], 'Li': [574, 2314, 3895], 'L.': [575, 859, 881, 1126, 1871, 2115, 2271, 2315, 3239, 3896, 4132], 'Diaz': [576], 'Herhal': [578, 2248], 'Koch': [580], '269:': [586, 604], '12684-12691Abstract': [587], '4Inagaki': [594], 'Y.': [595, 725, 778, 797, 877, 984, 1066, 1301, 1345, 1434, 1436, 1549, 1806, 1937, 2317, 2662, 2813, 3281, 3297, 3450, 3609, 3898, 4008], 'Truter': [596], 'S.': [597, 853, 939, 982, 1132, 1168, 1170, 1177, 1193, 1233, 1309, 1378, 1417, 1450, 1720, 1724, 1853, 1910, 2135, 2163, 3203, 3205, 3212, 3245, 3311, 3330, 3332, 4085, 4138], 'Ramirez': [598, 2229], 'F.': [599, 2230], '14828-14834Abstract': [605], '5Chung': [612], 'K-Y.': [613], 'Agarwal': [614], 'Uitto': [616, 2231, 2296], 'Mauviel': [618, 2298], '1996;': [623, 769, 786, 863, 1532, 1551, 1734, 2165], '271:': [624], '3272-3278Abstract': [625], '(316)': [633], 'Thus,': [636, 2333], 'plays': [638, 1991, 2100], 'crucial': [639], 'embryonic': [642], 'development': [643, 668], 'organogenesis,': [645], 'remodeling': [650], 'during': [651], 'wound': [652], 'healing': [653], 'repair.': [656], 'On': [657], 'other': [659, 848, 1163, 1274, 2388], 'hand,': [660], 'excessive': [661], 'implicated': [665, 1461], 'pathological': [670], 'fibrosis,': [671], '"dark': [673], 'horse': [674], 'repair"': [677], '(6Border': [678], 'W.A.': [679], 'Noble': [680], 'N.A.': [681], 'N.': [682, 1652, 1749, 1849, 2400], 'Engl.': [683], 'Med.': [685], '331:': [687], '1286-1292Crossref': [688], '(3024)': [691], 'initiates': [695], 'distinct': [700, 1617], 'transmembrane': [701], 'serine-threonine': [702], 'kinase': [703, 3590], 'receptors.': [704], 'Upon': [705, 2049], 'ligand': [706], 'binding,': [707], 'receptor': [711, 751, 1113, 1430, 2448], 'complex': [712, 3824], 'transiently': [713, 3666], 'interacts': [714], 'receptor-activated': [716, 962], 'Smads': [717, 1105, 1768, 3113], 'which': [718, 2724, 4062], 'propagate': [719], '(7Derynck': [722], 'R.': [723, 784, 801, 857, 937, 1349, 1722, 1788, 1810, 2398, 2402], 'Zhang': [724, 796, 1805], 'Feng': [726, 779, 798, 1346], 'X-H.': [727, 780, 799, 1347, 1804], 'Cell.': [728, 803, 862, 888, 1002, 1140, 1239, 1550, 1594, 1835, 2323, 3253, 3837, 3904, 4091, 4146], '1998;': [729, 889, 1141, 1182, 1203, 1351, 1399, 1419, 1598, 1795, 1813, 1836, 1860, 1877, 1912, 2302, 2431, 3217, 3254, 3285, 3348, 3839, 4147], '95:': [730, 1420, 1913], '737-740Abstract': [731], '(955)': [739], 'Smad2': [742, 976], 'direct': [746], 'substrates': [747], 'kinase,': [752], 'interact': [754, 1615, 1769], 'common': [757, 2190], 'partner': [758], 'Smad4': [759, 4168], '(8Lagna': [760], 'G.': [761, 1299, 1331, 2251, 2746, 3404], 'Hata': [762], 'Hemmati-Brivanlou': [764], 'Nature.': [768, 785, 949, 1334, 1350, 1531, 1659, 1733, 2751, 3284], '383:': [770, 787, 1735], '832-836Crossref': [771], '(809)': [774], '9Zhang': [777], 'Wu': [781, 1298, 1807], 'R-Y.': [782], 'Derynck': [783, 800, 1348, 1809], '168-171Crossref': [788], '(759)': [791], '10Wu': [794], 'R.Y.': [795, 1808], 'Mol.': [802, 1139, 1595, 1833, 3252, 4145], '1997;': [805, 950, 1003, 1335, 1681, 2012, 2137, 3178, 3313], '17:': [806, 1183, 3218], '2521-2528Crossref': [807], '(186)': [810], 'Smad4-containing': [813], 'heteromeric': [814], 'complexes': [816, 2058], 'then': [817, 3000, 3072], 'translocate': [818, 2061], 'from': [819, 922, 1109, 2619, 2630, 2639, 2649, 2957, 2970, 2976, 2985, 3083, 3087, 4202], 'cytoplasm': [821], 'into': [822, 2062, 3046], 'nucleus': [824], 'where': [825], 'they': [826], 'function': [827, 1033, 1482], 'regulators.': [830], 'Smads2–4': [831], 'share': [832], 'highly': [833], 'conserved': [834, 911, 1478, 1609], 'DNA-binding': [835], 'MH1': [836, 917], 'transactivating': [838], 'MH2': [839, 906, 1776], 'domains;': [840], 'latter': [842], 'also': [843, 1154, 2180], 'mediates': [844], 'interactions': [846, 1287, 2359], 'proteins': [849, 1480], '(11Macı́as-Silva': [850], 'M.': [851, 929, 941, 1070, 1235, 1329, 1333, 1438, 1440, 1446, 1654, 1745, 1753, 1857, 2006, 2666, 2732, 2817, 3174, 3326, 3454, 3613, 3833, 4012, 4087], 'Abdollah': [852, 981], 'Hoodless': [854], 'P.A.': [855], 'Pirone': [856], 'Attisano': [858], 'Wrana': [860, 998], 'J.L.': [861, 935, 999, 1128, 3241, 4134], '87:': [864, 1552], '1215-1224Abstract': [865], '(650)': [873], '12Shi': [876], 'Wang': [878, 1371, 1831, 2270], 'Y.F.': [879], 'Jayaraman': [880, 1870], 'Yang': [882], 'H.': [883, 980, 1747, 3170, 3389], 'Pavletich': [886], 'N.P.': [887], '94:': [890, 2138, 3314], '585-594Abstract': [891], '(612)': [899], 'Smad7': [902, 964, 1025, 3323], 'contains': [903, 1120, 4063], 'characteristic': [905], 'domain,': [907], 'but': [908, 2188], 'lacks': [909], 'SSXS': [912], 'phosphorylation': [913, 974], 'motif,': [914], 'domain': [918, 1777], 'shows': [919], 'marked': [920, 3674], 'divergence': [921], '(13Nakao': [926], 'Afrakhte': [928], 'Morén': [930], 'Nakayama': [932], 'Christian': [934], 'Heuchel': [936], 'Itoh': [938, 1169, 1192, 3204, 3331], 'Kawabata': [940, 1445, 1752, 1856], 'Heldin': [942, 944, 1194, 3337, 3339], 'N.E.': [943, 2404, 3340], 'C.H.': [945, 3338], 'ten': [946, 1173, 3208, 3341], 'Dijke': [947, 1174, 3209, 3342], 'P.': [948, 1130, 1175, 1197, 1696, 3210, 3243, 3279, 3343, 4136], '389:': [951, 1336], '631-635Crossref': [952], '(1572)': [955], 'Furthermore,': [958, 1508, 3870], 'Smads,': [963, 4210], 'stably': [965], 'binds': [966], 'receptors': [969], 'interferes': [971], 'ligand-induced': [973], '(14Hayashi': [979], 'Qiu': [983], 'Cai': [985], 'Xu': [987, 2114], 'Y.Y.': [988], 'Grinnell': [989], 'B.W.': [990], 'Richardson': [991], 'M.A.': [992, 997, 1904], 'Topper': [993], 'J.N.': [994, 1891], 'Gimbrone': [995, 1902], 'Jr.,': [996, 1903, 2156], 'Falb': [1000, 1898], 'D.': [1001, 1172, 1411, 1694, 1899, 2121, 2152, 2456, 2738, 3207], '89:': [1004], '1165-1173Abstract': [1005], '(1169)': [1013], 'Because': [1016, 2343, 3985], 'expression': [1018, 2393, 2419, 2449, 2730, 3017, 3703, 4172, 4204], 'markedly': [1020, 1055, 1925], 'ligand,': [1024], 'serve': [1028], 'an': [1029, 2082, 2101, 2580, 3231, 3376, 3412, 3782], 'autoregulatory': [1030], 'negative': [1031, 1095, 3699], 'feedback': [1032], 'signaling.': [1037], 'overexpression': [1043, 2556], 'primary': [1047, 2949, 3078], 'mimicked': [1050], 'action': [1052], 'TGF-β,': [1054, 3151], 'inducingCOL1A2': [1056], 'vitro': [1060], '(15Chen': [1061, 2657, 2808, 3445, 3604, 4003], 'S-J.': [1062, 1229, 2658, 2809, 3446, 3605, 4004, 4081], 'Yuan': [1063, 1230, 1934, 2659, 2810, 3447, 3606, 4005, 4082], 'W.': [1064, 1199, 1231, 1935, 2150, 2311, 2660, 2811, 3448, 3607, 3827, 3892, 4006, 4083], 'Mori': [1065, 1936, 2316, 2661, 2812, 3449, 3608, 3897, 4007], 'Levenson': [1067, 2663, 2814, 3451, 3610, 4009], 'Trojanowska': [1069, 1234, 2665, 2816, 3173, 3453, 3612, 4011, 4086], 'Invest.': [1074, 2235, 2259, 2277, 2670, 2821, 3458, 3617, 4016], 'Dermatol.': [1075, 2278, 2671, 2822, 3459, 3618, 4017], '1999;': [1076, 1311, 1380, 1452, 1759, 2325, 2672, 2823, 3460, 3619, 3906, 4018], '112:': [1077, 2673, 2824, 3461, 3620, 4019], '49-57Abstract': [1078, 2674, 2825, 3462, 3621, 4020], '(376)': [1086, 2682, 2833, 3470, 3629, 4028], 'Transactivation': [1089], 'was': [1090, 2533, 2629, 2838, 3035, 3116, 3124, 3481, 3689, 3720, 3731, 3800, 3887, 3966, 4039, 4048, 4101, 4111], 'blocked': [1091], 'phosphorylation-defective': [1093], 'dominant': [1094], 'mutants': [1096], 'Smad3,': [1098, 2864, 4056], 'establishing': [1099], 'critical': [1101, 1969], 'role': [1102, 1970, 2104, 3992], 'endogenous': [1104, 3022, 4165, 4195], 'transducing': [1107], 'information': [1108], 'these': [1115, 1270, 1518, 2344, 3915, 4177], 'cells.': [1116], 'Smad3/Smad4-binding': [1121], 'consensus': [1122, 3234, 3236, 3579, 3796, 3865, 4129], '"CAGA': [1123], 'boxes"': [1124], '(16Zawel': [1125, 3238, 4131], 'Dai': [1127, 3240, 4133], 'Buckhaults': [1129, 3242, 4135], 'Zhou': [1131, 3244, 4137], 'Kinzler': [1133, 3246, 4139], 'K.W.': [1134, 3247, 4140], 'Vogelstein': [1135, 3248, 4141], 'B.': [1136, 2425, 2454, 3249, 3336, 4142], 'Kern': [1137, 3250, 4143], 'S.E.': [1138, 3251, 4144], '1:': [1142, 3255, 4148], '611-617Abstract': [1143, 3256, 4149], '(892)': [1151, 3264, 4157], 'Scholar),': [1153, 1215, 1342, 1387, 1406, 1426, 2417, 2443, 2684, 2759, 3190, 3224, 3292, 3320, 3355, 3401, 3563, 4030], 'found': [1155, 2792], 'promoters': [1158, 1257], 'PAI-1,': [1160], 'junB,': [1161], 'inducible': [1165], '(17Dennler': [1167, 3202], 'Vivien': [1171, 3206], 'Huet': [1176, 3211], 'Gauthier': [1178, 3213], 'J.M.': [1179, 3214], 'EMBO': [1180, 1709, 3215], '3091-3100Crossref': [1184, 3219], '(1588)': [1187, 3222], '18Jonk': [1190], 'L.J.C.': [1191], 'C.-H.': [1195], 'ten-Dijke': [1196], 'Kruijer': [1198], '273:': [1204, 1878, 2432], '21145-21152Abstract': [1205], '(513)': [1213], 'necessary': [1218, 3697], 'sufficient': [1220, 4075], 'mediate': [1222, 4077], '(19Chen': [1228, 4080], 'Lo': [1232, 4084], 'Physiol.': [1240, 2324, 3838, 3905, 4092], '2000;': [1241, 1941, 2410, 4093], '183:': [1242, 4094], '381-392Crossref': [1243, 4095], '(171)': [1246, 4098], 'However,': [1249], 'asCAGA': [1250], 'boxes': [1251], 'widely': [1253], 'distributed': [1254], 'mammalian': [1259], 'genes,': [1260, 2187], 'affinity': [1263], 'specificity': [1265], 'SMAD': [1267], 'binding': [1268, 1624, 4207], 'relatively': [1272], 'low,': [1273], 'likely': [1278, 2364], 'contribute': [1280], 'specific': [1283], 'tight': [1285], 'Smad-DNA': [1286], 'required': [1290], '(20Hua': [1294], 'X.': [1295, 1323, 1366, 1390, 1392, 1822, 3295], 'Miller': [1296], 'Z.A.': [1297], 'Shi': [1300], 'Lodish': [1302, 1395, 3304], 'H.F.': [1303, 1396, 3305], 'Proc.': [1304, 1373, 1412, 1905, 2130, 2158, 3306], 'Natl.': [1305, 1374, 1413, 1906, 2131, 2159, 3307], 'Acad.': [1306, 1375, 1414, 1907, 2132, 2160, 3308], 'Sci.': [1307, 1376, 1415, 1597, 1908, 2133, 2161, 3309], 'U.': [1308, 1377, 1416, 1909, 2002, 2134, 2148, 2162, 3310], '96:': [1312, 1381], '13130-13135Crossref': [1313], '(134)': [1316, 3188], 'Cooperation': [1319], 'FAST-1': [1321], '(21Chen': [1322], 'Weisberg': [1324], 'E.': [1325, 1726, 2117, 2119, 3301], 'Fridmacher': [1326], 'V.': [1327, 1545, 2269, 3283], 'Watanabe': [1328, 1439], 'Naco': [1330], 'Whitman': [1332], '85-89Crossref': [1337], '(494)': [1340], 'AP-1': [1343], '(22Zhang': [1344], '394:': [1352], '909-913Crossref': [1353], '(688)': [1356], '23Liberati': [1359], 'N.T.': [1360, 1826], 'Datto': [1361, 1827], 'M.B.': [1362, 1828], 'Frederick': [1363, 1829], 'J.P.': [1364, 1830], 'Shen': [1365], 'Wong': [1367], 'C.': [1368, 1869, 2406, 2736, 2750], 'Rougier-Chapman': [1369], 'E.M.': [1370], 'X.F.': [1372, 1832], '4844-4849Crossref': [1382], '(275)': [1385], 'TFE3': [1388], '(24Hua': [1389], 'Liu': [1391], 'Ansari': [1393], 'D.O.': [1394], '12:': [1400, 1796, 1814], '3084-3095Crossref': [1401], '(259)': [1404], 'Sp1': [1407], '(25Moustakas': [1408], 'Kardassis': [1410], '6733-6738Crossref': [1421], '(321)': [1424], 'vitamin': [1428], 'D': [1429], '(26Yanagisawa': [1431], 'Yanagi': [1433], 'Masuhiro': [1435], 'Suzawa': [1437], 'Kashiwagi': [1441], 'K.': [1442, 1448, 1675, 1743, 1755, 1855, 2291, 3334], 'Toriyabe': [1443], 'Miyazono': [1447, 1754, 1854], 'Kato': [1449, 1852], 'Science.': [1451, 1680, 1758, 2040], '283:': [1453], '1317-1321Crossref': [1454], '(420)': [1457], 'Scholar)': [1459, 3266, 4100], 'Smad-mediated': [1463, 2589], 'TGF-β-responsive': [1466], '(CBP)': [1470], 'adenovirus': [1472], 'E1A-associated': [1473], 'structurally': [1477], 'large': [1479], 'several': [1487], 'pathways.': [1490], 'enhance': [1492], 'bridging': [1495], 'DNA-bound': [1496], 'basal': [1500], 'machinery,': [1502], 'thereby': [1503], 'stabilizing': [1504], 'pre-initiation': [1506], 'complex.': [1507], 'nature': [1510], 'intrinsic': [1513], 'histone': [1514, 1565], 'enzyme': [1516], 'activity,': [1517], 'acetylate': [1520], 'amino-terminal': [1521, 2096], 'lysine': [1522], 'residues': [1523], 'nucleosomal': [1525, 1568], 'histones': [1526], '(27Bannister': [1527], 'A.J.': [1528, 1690, 1706, 1897], 'Kouzarides': [1529, 1697, 1707], '384:': [1533], '641-643Crossref': [1534], '(1535)': [1537], '28Ogryzko': [1540], 'V.V.': [1541], 'Schiltz': [1542], 'R.L.': [1543], 'Russanova': [1544], 'Howard': [1546, 2007], 'B.H.': [1547], 'Nakatani': [1548, 3280], '953-959Abstract': [1553], '(2409)': [1561], 'Local': [1564], 'hyperacetylation': [1566], 'causes': [1567], 'relaxation,': [1569], 'thus': [1570, 2079], 'promoting': [1571], 'access': [1572], 'DNA': [1578, 3477, 4206], 'sequences.': [1579], 'strongly': [1586], 'correlated': [1587], 'acetylation': [1590], 'state': [1591], '(29Turner': [1592], 'B.M.': [1593], 'Life': [1596, 2620], '54:': [1599], '21-31Crossref': [1600], '(177)': [1603], 'protein-binding': [1610], 'domains': [1611], 'enables': [1612], 'classes': [1618], 'factors.': [1622], 'Through': [1623], 'CREB,': [1626], 'p65': [1628], 'component': [1629], 'NF-κB,': [1631], 'c-Jun,': [1633], 'c-Fos': [1635], 'components': [1636], 'AP-1,': [1638], 'Stats,': [1640], 'converging': [1643], 'signaling': [1645, 2475, 2530], '(30Chrivia': [1647], 'J.C.': [1648, 1673, 2008], 'Kwok': [1649], 'R.P.': [1650], 'Lamb': [1651], 'Hagiwara': [1653], 'Montminy': [1655], 'M.R.': [1656, 1893], 'Goodman': [1657], 'R.H.': [1658], '1993;': [1660, 2752], '365:': [1661], '855-859Crossref': [1662], '(1770)': [1665], '31Perkins': [1668], 'N.D.': [1669], 'Felzien': [1670], 'L.K.': [1671], 'Betts': [1672], 'Leung': [1674], 'Beach': [1676], 'D.H.': [1677], 'Nabel': [1678], 'G.J.': [1679], '275:': [1682], '523-527Crossref': [1683], '(666)': [1686], '32Bannister': [1689], 'Oehler': [1691], 'Wilhelm': [1693], 'Angel': [1695], 'Oncogene.': [1699, 1940, 2409], '1995;': [1700, 1711, 2279], '11:': [1701], '2509-2514PubMed': [1702], '33Bannister': [1705], '14:': [1712], '4758-4762Crossref': [1713], '(319)': [1716], '34Bhattacharya': [1719], 'Eckner': [1721], 'Grossman': [1723], 'Oldread': [1725], 'Arany': [1727], 'Z.': [1728], "D'Andrea": [1729], 'Livingston': [1731], '344-347Crossref': [1736], '(423)': [1739, 2170], '35Nakashima': [1742], 'Yanagisawa': [1744, 1850], 'Arakawa': [1746], 'Kimura': [1748], 'Hisatsune': [1750], 'Taga': [1756], '284:': [1760], '479-482Crossref': [1761], '(730)': [1764], 'Receptor-activated': [1767], 'directly': [1770, 2067, 2912, 4051], 'via': [1773], 'COOH-terminal': [1781], 'region': [1782, 3708], 'overlapping': [1783], 'E1A-binding': [1785], 'site': [1786], '(36Janknecht': [1787], 'Wells': [1789], 'N.J.': [1790], 'Hunter': [1791], '2114-2119Crossref': [1797], '(437)': [1800], '37Feng': [1803], '2153-2163Crossref': [1815], '(451)': [1818], '38Shen': [1821], 'Hu': [1823], 'P.P.': [1824], 'Liberati': [1825], '9:': [1837], '3309-3319Crossref': [1838], '(185)': [1841], '39Nishihara': [1844], 'Hanai': [1846], 'J.I.': [1847], 'Okamoto': [1848], 'Gene': [1858], 'Cells.': [1859], '3:': [1861], '613-623Crossref': [1862], '(130)': [1865], '40Pouponnot': [1868], '22865-22868Abstract': [1879], '(290)': [1887], '41Topper': [1890], 'Dichiara': [1892], 'Brown': [1894, 2272], 'J.D.': [1895], 'Williams': [1896], 'Collins': [1900], '9506-9511Crossref': [1914], '(153)': [1917], 'demonstrated': [1922], 'enhanced': [1926], '(42Ghosh': [1932], 'A.K.': [1933], '19:': [1942, 2411, 3557], '3546-3555Crossref': [1943], '(203)': [1946], 'By': [1949], 'competing': [1950], 'p300/CBP,': [1959], 'adenoviral': [1961], 'oncoprotein': [1962], 'E1A': [1963], 'abrogated': [1964, 2516, 3691], 'transactivation,': [1966], 'indicating': [1967, 3694], 'fibroblasts.': [1978, 2498, 3528, 3939], 'Interferon-γ': [1979], '(IFN-γ),': [1980], 'pleiotropic': [1982], 'cytokine': [1983], 'produced': [1984], 'T': [1986], 'NK': [1989], 'cells,': [1990], 'fundamental': [1992, 3991], 'innate': [1996], 'acquired': [1998], 'immune': [1999], '(43Boehm': [2001], 'Klamp': [2003], 'Groot': [2005], 'Annu.': [2009], 'Rev.': [2010], 'Immunol.': [2011, 2462, 3397], '15:': [2013], '749-795Crossref': [2014], '(2505)': [2017], 'Transcriptional': [2020], 'mediated': [2029, 2535, 4188], 'pathway': [2033, 4038], '(44Darnell': [2034], 'J.E.': [2035, 2157], 'Kerr': [2036], 'I.M.': [2037], 'Stark': [2038], 'G.R.': [2039], '264:': [2042], '1415-1419Crossref': [2043], '(5062)': [2046], 'tyrosine-phosphorylated': [2053], 'cytoplasmic': [2054, 3142], 'forms': [2056], 'homodimeric': [2057], 'can': [2060, 2179, 4226], 'nucleus,': [2064], 'bind': [2066], 'palindromic': [2069, 3233], '(GAS)': [2072], 'IFN-γ-responsive': [2074, 3377, 3413], 'promoters.': [2077], 'serves': [2080], 'mediator': [2084, 3784], 'IFN-γ-induced': [2086, 2109, 2728], 'physically': [2090], 'associates': [2091], 'near': [2094], 'domain;': [2097], 'this': [2098, 3041, 3707, 4109], 'functional': [2103], '(45Horvai': [2112], 'A.E.': [2113], 'Korzus': [2116], 'Brard': [2118], 'Kalafus': [2120], 'Mullen': [2122], 'T.M.': [2123], 'Rose': [2124], 'D.W.': [2125, 2127], 'Rosenfeld': [2126], 'Glass': [2128], 'C.K.': [2129], '1074-1079Crossref': [2139], '(388)': [2142], '46Zhang': [2145], 'J.J.': [2146], 'Vinkemeier': [2147], 'Gu': [2149], 'Chakravarti': [2151], 'Horvath': [2153], 'C.M.': [2154], 'Darnell': [2155], '93:': [2166], '15092-15096Crossref': [2167], 'addition': [2174, 3485], 'stimulation,': [2177], 'regulate': [2182, 2571], 'selected': [2186], 'no': [2189, 4162], 'IFN-γ-specific': [2191], 'inhibitory': [2192, 3727, 3879, 4044], 'elements': [2193, 3868], 'been': [2195], 'identified.': [2196], 'others': [2199], 'inhibits': [2205], 'independent': [2212], 'Stat1-promoter': [2214], 'interactions,': [2215], '(47Kähäri': [2223], 'V.-M.': [2224], 'Chen': [2225, 2318, 3899], 'Y.Q.': [2226], 'Su': [2227], 'M.W.': [2228], 'Clin.': [2234, 2258], '1990;': [2236, 2260], '86:': [2237], '1489-1495Crossref': [2238], '(167)': [2241], '48Varga': [2244], 'Constantine': [2250], 'Rosenbloom': [2252], 'Jimenez': [2254], 'Eur.': [2256], '20:': [2261], '487-493Crossref': [2262], '49Yufit': [2266], 'Vining': [2268], 'R.R.': [2273], '105:': [2280], '388-393Abstract': [2281], '(23)': [2287], '50Higashi': [2290], 'Kouba': [2292], 'D.J.': [2293], 'Song': [2294], 'Y.J.': [2295], 'Matrix': [2300], '16:': [2303], '447-456Crossref': [2304], '(39)': [2307], '51Yuan': [2310], 'Yufit': [2312, 3830, 3893], 'S.J.': [2319, 3900], '179:': [2326, 3907], '97-108Crossref': [2327, 3908], '(55)': [2330, 2415, 3911], 'opposite': [2338], 'synthesis.': [2342], 'secreted': [2348], 'inflammatory': [2350], 'at': [2352, 2695, 2994], 'injury,': [2356], 'regulating': [2360], 'be': [2366, 2548, 3923, 4074], 'great': [2368], 'importance': [2369], 'maintenance': [2372], 'homeostasis.': [2376], 'As': [2377, 3362, 3807], 'well': [2378], 'suppressing': [2380], 'TGFβ': [2389], 'including': [2391], 'collagenase-3': [2392], 'epithelial': [2395], '(52Ala-Aho': [2397], 'Johansson': [2399], 'Grenman': [2401], 'Fusenig': [2403], 'Lopez-Otin': [2405], 'Kähäri': [2407], 'V.M.': [2408], '248-257Crossref': [2412], 'perlecan': [2418], 'colon': [2421], 'carcinoma': [2422], '(53Sharma': [2424], 'Iozzo': [2426], 'R.V.': [2427], '4642-4646Abstract': [2433], '(57)': [2441], 'fibronectin': [2445], 'laminin': [2447], 'monocytic': [2451], '(54Bauvois': [2453], 'Rouillard': [2455], 'Sanceau': [2457], 'Wietzerbin': [2459], '1992;': [2463, 3398], '148:': [2464, 3399], '3912-3919PubMed': [2465], 'basis': [2469], 'underlying': [2470], 'incompletely': [2479], 'understood.': [2480], 'present': [2483], 'report,': [2484], 'we': [2485, 2791, 3986], 'characterized': [2486], 'repression': [2488], 'stimulatory': [2504, 2540], 'Type': [2509], 'were': [2515, 2617, 2647, 2693, 2762, 2774, 2779, 2857, 2873, 2898, 2910, 2935, 2999, 3044, 3071, 3106, 3267, 3360, 3425, 3429, 3502, 3524, 3539, 3567, 3585, 3599, 3637, 3652, 3665, 3704, 3941, 3959, 4123], 'minimal': [2521, 4059], 'COL1A2promoter.': [2526], 'Inhibition': [2527, 3761, 4198], 'not': [2534, 2726, 3766, 3849, 3922, 4174, 4200], 'Smad7.': [2538], 'effect': [2541, 3728, 3880, 4163], 'could': [2547, 3921], 'rescued': [2549], 'p300.': [2558], 'IFN-γ/TGF-β-induced': [2565], 'suggest': [2578], 'increase': [2581, 4105], 'IFN-γ-treated': [2586, 4114], 'suppressed': [2588, 4112, 4182], 'transactivation': [2590], 'titrating': [2592], 'away': [2593], 'coactivators.': [2595], 'provide': [2598], 'understanding': [2600], 'physiologically': [2603], 'cytokines.': [2612], 'All': [2613], 'culture': [2615], 'reagents': [2616], 'obtained': [2618, 4124], 'Technologies,': [2621, 2844], 'Inc.': [2622, 2632], '(Grand': [2623], 'Island,': [2624], 'NY).': [2625], 'Recombinant': [2626], 'human': [2627, 3162], 'Genentech': [2631], '(South': [2633], 'San': [2634, 2964], 'Francisco,': [2635, 2965], 'CA),': [2636, 3441], 'Amgen': [2640], '(Thousand': [2641], 'Oaks,': [2642], 'CA).': [2643, 2933], 'Primary': [2644], 'cultures': [2646, 2778, 2807], 'established': [2648, 3989], 'neonatal': [2650], 'foreskin': [2651], 'described': [2654, 3443, 3602, 3972], 'explant': [2655], 'techniques': [2656], 'studied': [2686, 3036], 'passages': [2688], '4': [2689], '8.': [2691], 'Cells': [2692], 'grown': [2694], '37': [2696], '°C': [2697], '5‥': [2700], 'CO2': [2701], 'atmosphere': [2702], 'modified': [2704], "Eagle's": [2705], 'medium': [2706], 'supplemented': [2707], '1‥': [2709, 2715], '10‥': [2711], 'fetal': [2712, 3056, 3515], 'calf': [2713, 3057, 3516], 'serum,': [2714], 'vitamins,': [2716], '2': [2718, 2992, 3067, 3946], 'mml-glutamine.': [2719], 'U4AJak1-deficient': [2721], 'line,': [2723], 'does': [2725], 'support': [2727], '(55Muller': [2731], 'Briscoe': [2733], 'Laxton': [2735], 'Guschin': [2737], 'Ziemiecki': [2739], 'Silvennoinen': [2741], 'O.': [2742, 2767], 'Harpur': [2743], 'A.G.': [2744], 'Barbieri': [2745], 'Witthuhn': [2747], 'B.A.': [2748], 'Schindler': [2749], '366:': [2753], '129-135Crossref': [2754], '(646)': [2757], 'U4A/Jak1': [2761], 'kind': [2764], 'gift': [2765], 'Colamonici.': [2768], 'added': [2775, 3061, 3525], 'simultaneously,': [2776], 'harvested': [2780], 'following': [2781, 2846], '24–48': [2782, 2883], 'h': [2783, 2884, 2924, 2993, 3068], 'incubation.': [2784], 'previous': [2786], 'studies': [2787], 'under': [2788, 3973], 'similar': [2789], 'conditions,': [2790], 'neither': [2794], 'nor': [2796], 'significantly': [2798], 'effected': [2799], 'number': [2801], 'viability': [2803], 'confluent': [2805, 3527], 'fibroblast': [2806], 'Total': [2836], 'RNA': [2837], 'isolated': [2839], 'TRIZOL': [2841], 'Reagent': [2842], '(Life': [2843], 'Inc.)': [2845], 'indicated': [2848, 2893, 3496, 3534, 4179], 'periods': [2849], 'incubation,': [2851, 2896, 3069], 'mRNA': [2856, 4169], 'examined': [2858, 3117], 'Northern': [2860], 'analysis': [2861, 3640, 3853], 'using': [2862, 2925, 3436, 3569, 3587], 'radiolabeled': [2863], 'Smad7,': [2865], 'andglyceraldehyde-3-phosphate': [2866], 'dehydrogenase': [2867], 'cDNA': [2868, 3324], 'probes.': [2869], 'cDNA-mRNA': [2871], 'hybrids': [2872], 'visualized': [2874, 3013], 'autoradiography': [2876], 'Kodak': [2878], 'X-AR5': [2879], 'films': [2880], 'exposed': [2881], 'intensifying': [2886], 'screens.': [2887], 'At': [2888, 3529, 3951], 'end': [2890, 3531, 3953], 'period': [2894], 'washed': [2899], 'ice-cold': [2901], 'phosphate-buffered': [2902], 'saline,': [2903], 'whole': [2905], 'lysates': [2907], 'prepared.': [2908], 'Lysates': [2909], 'either': [2911], 'resolved': [2913], 'electrophoresis': [2915], 'polyacrylamide': [2917], 'gels,': [2918], 'first': [2920], 'immunoprecipitated': [2921], '1': [2923, 3091, 3737, 3759, 4117], 'anti-p300': [2926], 'antibody': [2927], '(Santa': [2928, 3099], 'Cruz': [2929, 2932], 'Biotechnology,': [2930], 'Santa': [2931, 2958, 3084], 'Gels': [2934], 'blotted': [2936], 'onto': [2937], 'polyvinylidene': [2938], 'difluoride': [2939], 'membranes': [2940], '(Millipore,': [2941], 'Bedford,': [2942], 'MA),': [2943], 'subjected': [2945], 'immunoblotting': [2947], 'antibodies': [2950, 3079, 3098], '(human': [2951], 'anti-p300,': [2952], 'anti-Smad7,': [2953], 'anti-actin': [2955], '(C-2)': [2956], 'Cruz;': [2959, 3085], 'anti-Smad3': [2960], 'fromZymed': [2961], 'Laboratories': [2962], 'Inc.,': [2963], 'CA;': [2966], 'anti-Type': [2967], 'Southern': [2971], 'Biotech': [2972], '(Birmingham,': [2973], 'AL);': [2974], 'anti-Stat1': [2975], 'Transduction': [2977, 3088], 'Labs': [2978], '(Lexington,': [2979], 'KY);': [2980], 'anti-phosphotyrosine': [2982], 'Stat1': [2983, 3115, 3793, 3936], '(Y701)': [2984], 'Upstate': [2986], 'Biotechnology': [2987], '(Lake': [2988], 'Placid,': [2989], 'NY)': [2990], 'room': [2995], 'temperature.': [2996], 'blots': [2998], 'washed,': [3001], 'followed': [3002, 3093], 'incubation': [3004, 3493, 3535, 3956], 'appropriate': [3007, 3357, 3487], 'horseradish': [3008, 3095], 'peroxidase-conjugated': [3009, 3096], 'secondary': [3010, 3097], 'antibody,': [3011], 'chemiluminescence.': [3015], 'intracellular': [3019, 3110, 3744], 'localization': [3020], 'SMADs': [3023], 'absence': [3030], 'indirect': [3038], 'immunofluorescence.': [3039, 3143], 'For': [3040], 'purpose,': [3042], 'seeded': [3045], 'chamber': [3047], 'glass': [3048], 'slides': [3049, 3105], 'incubated': [3051, 3076], 'media': [3053, 3512], '0.1‥': [3055], 'serum': [3058, 3517], '30': [3062], 'min': [3063, 3815], 'before': [3064], 'After': [3066, 3101], 'fixed': [3073], 'methanol,': [3075], '(anti-Smad3': [3080], 'anti-Smad4': [3082], 'anti-Stat1α': [3086], 'Labs)': [3089], 'h,': [3092, 3947], 'Cruz).': [3100], 'three': [3102], 'washes,': [3103], 'stained,': [3107], 'distribution': [3111], 'fluorescence': [3119], 'confocal': [3121, 3969], 'microscopy.': [3122], 'Quantitation': [3123], 'performed': [3125, 3430, 3600], 'blinded': [3128], 'fashion': [3129], 'scoring': [3131], '100': [3132], 'different': [3135], 'fields': [3136], 'showing': [3138], 'predominantly': [3139], 'To': [3144, 3655, 3790, 4050], 'measure': [3145], '772COL1A2/CAT': [3152], 'consisting': [3153], '−772': [3156], '+58': [3158], 'bp': [3159, 3198, 3682], 'segment': [3160, 3379, 3415], 'linked': [3165], 'theCAT': [3167], '(56Ihn': [3169], 'LeRoy': [3171], 'E.C.': [3172], '272:': [3179], '24666-24672Abstract': [3180], 'CAGA-COL1A2/luc': [3191], 'containing': [3192, 3226, 3375, 3411, 4127], 'six': [3193, 4064], 'copies': [3194, 4066], '−266/−258': [3197], 'sequence': [3199, 3237], 'orSBE4-luc': [3225], 'four': [3227], 'tandem': [3228, 4065], 'repeats': [3229], '8-bp': [3232], 'used.': [3268, 3426, 4102], 'Expression': [3269], 'vectors': [3270, 3359], 'wild': [3272], 'ΔHAT-mutant': [3275], 'p300(57Boyes': [3276], 'Byfield': [3278], 'Ogryzko': [3282], '396:': [3286], '594-598Crossref': [3287], '(633)': [3290], '(58Liu': [3294], 'Sun': [3296], 'Constantinescu': [3298], 'S.N.': [3299], 'Karam': [3300], 'Weinberg': [3302], '10669-10674Crossref': [3315], '(331)': [3318], 'antisense': [3322], '(59Afrakhte': [3325], 'Moren': [3327], 'Jossan': [3329], 'Sampath': [3333], 'Westermark': [3335], 'Biochem.': [3344], 'Biophys.': [3345], 'Res.': [3346, 3555], 'Commun.': [3347], '249:': [3349], '505-511Crossref': [3350], '(299)': [3353], 'control': [3358], 'transfected.': [3361], 'controls,': [3363], 'Δ-152DR-CAT': [3364], '(from': [3365, 3403], 'Ting,': [3367], 'University': [3368], 'North': [3370], 'Carolina,': [3371], 'Chapel': [3372], 'Hill,': [3373], 'NC)': [3374], '152-bp': [3378], 'theHLA-DR': [3381], 'ligated': [3383, 3420], 'CAT': [3386, 3423, 3677], '(60Moses': [3388], 'Panek': [3390], 'R.B.': [3391], 'Benveniste': [3392], 'E.N.': [3393], 'Ting': [3394], 'JP-Y.': [3395], '3642-3651Google': [3400], 'andGAS-tk-CAT': [3402], 'Sen,': [3405], 'Cleveland': [3406], 'Clinic': [3407], 'Foundation': [3408], 'Research': [3409], 'Institute)': [3410], '24-bp': [3414], 'IRF-1': [3418], 'gene,': [3424], 'Transient': [3427], 'transfections': [3428], 'calcium': [3432], 'phosphate/DNA': [3433], 'co-precipitation': [3434], 'Superfect': [3437], 'reagent': [3438], '(Qiagen,': [3439], 'Valencia,': [3440], 'total': [3474], 'amount': [3475], 'each': [3479], 'transfection': [3480], 'kept': [3482], 'constant': [3483], 'empty': [3488], 'vectors,': [3489], 'required.': [3491], 'Following': [3492], 'CAT,': [3498], 'luciferase': [3500], 'activities': [3501, 4045], 'determined': [3503, 3568, 3638], 'duplicate': [3505], 'normalized': [3507], 'concentration.': [3510], 'Fresh': [3511], '0.2‥': [3514], 'alone': [3520], 'periods,': [3536], 'extracts': [3538], 'prepared': [3540], 'according': [3541], 'method': [3544], 'Andrews': [3546], 'Faller': [3548, 3551], '(61Andrews': [3549], 'N.C.': [3550], 'D.V.': [3552], 'Nucleic': [3553], 'Acids': [3554], '1991;': [3556], '2499Crossref': [3558], '(2214)': [3561], 'concentrations': [3566], 'Bio-Rad': [3571], 'assay.': [3572], 'Double-stranded': [3573], 'oligonucleotide': [3574, 3799], 'probes': [3575, 3584], 'corresponding': [3576], '(SBE).': [3582], 'end-labeled': [3586], 'T4': [3588], 'polynucleotide': [3589], '(Promega,': [3591], 'Madison': [3592], 'WI).': [3593], 'Electrophoretic': [3594], 'gel': [3595, 3805], 'mobility': [3596], 'shift': [3597], 'assays': [3598], 'Statistical': [3632], 'differences': [3633], 'experimental': [3635], 'groups': [3636], 'variance,': [3642], 'values': [3644], 'p': [3646], '<': [3647], '0.05': [3648], "Fisher's": [3650], 'test': [3651], 'considered': [3653], 'significant.': [3654], 'examine': [3656, 3792, 4052], 'transfected': [3667], 'promoter-CATreporter': [3670], 'constructs.': [3671], 'caused': [3673], 'driven': [3679], '772': [3681], 'promoter.': [3686], 'This': [3687], 'induction': [3688], 'completely': [3690], 'cis-elements': [3696], 'contained': [3705], 'within': [3706], '(Fig.1': [3712], 'A,': [3713, 3738, 4118], 'left': [3714, 3949], 'panel).': [3715, 3740, 4120], 'Δ152DR-CAT': [3719], 'demonstrating': [3724], 'selective': [3732], 'theCOL1A2': [3734], '(Fig.': [3736, 3758, 4116], 'middle': [3739], 'Changes': [3741], 'pool': [3745], 'response': [3749], 'paralleled': [3753], 'those': [3754], 'B).': [3760], 'did': [3765, 4199], 'require': [3767], 'pretreatment': [3768], 'prior': [3771], 'stimulation.': [3773], 'rapid': [3777], 'translocation': [3779], 'Stat1,': [3781], '(Fig.2).': [3789], 'further': [3791], 'activation,': [3794], 'Stat1α-binding': [3797, 3866], 'GAS': [3798, 3867], 'used': [3801], 'probe': [3803], 'shifts.': [3806], 'expected,': [3808], 'treatment': [3810], '15': [3814], 'resulted': [3816], 'formation': [3819], 'GAS-specific': [3822], 'DNA-protein': [3823], '(Ref.': [3825], '62Yuan': [3826], 'Collado-Hidalgo': [3828], 'Taylor': [3832], '177:': [3840], '174-186Crossref': [3841], '(87)': [3844], 'Scholar;': [3846], 'data': [3848], 'shown).': [3850, 4175], 'A': [3851], 'careful': [3852], 'proximal': [3856], 'identify': [3861], '(TTN5AA).': [3869], 'classical': [3874], 'Stat1-mediated': [3875], 'delayed': [3888], '(>8': [3889], 'h)': [3890], '(51Yuan': [3891], 'Therefore,': [3914], 'observations': [3916], 'suggested': [3917], 'activation': [3920, 3937], 'fully': [3924], 'responsible': [3925], 'suppression': [3927], 'COL1A2transcription': [3929], '.Figure': [3932], '2IFN': [3933], '-γ': [3934], 'induces': [3935], 'Fibroblasts': [3940], 'treated': [3942], 'untreated.': [3950], 'period,': [3957], 'processed': [3960], 'immunocytochemistry,': [3962], 'STAT1-specific': [3964], 'immunofluorescence': [3965], 'detected': [3967], 'microscopy,': [3970], '"Materials': [3974], 'Methods."View': [3976], 'Large': [3977], 'Image': [3978], 'Figure': [3979], 'ViewerDownload': [3980], 'Hi-res': [3981], 'image': [3982], 'Download': [3983], '(PPT)': [3984], 'possibility': [4032], 'considered.': [4049], 'involvement': [4054], 'heterologous': [4058], 'construct': [4060], 'CAGA-COL1A2/luc,': [4061], 'CAGAelement': [4071], 'right': [4119], 'Identical': [4121], 'SBE4-luc,': [4126], 'SBE': [4130], 'had': [4161], '(data': [4173], 'Together,': [4176], 'multimerized': [4190], 'Smad3-recognition': [4191], 'sites,': [4192], 'while': [4193], 'inducing': [4194], 'activation.': [4197], 'result': [4201], 'decreased': [4203], 'suggesting': [4211], 'instead': [4212], 'targeted': [4215], 'Intracellular': [4219], 'cross-talk': [4220], 'among': [4221]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1983640618', 'counts_by_year': [{'year': 2024, 'cited_by_count': 4}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 7}, {'year': 2019, 'cited_by_count': 6}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 8}, {'year': 2016, 'cited_by_count': 6}, {'year': 2015, 'cited_by_count': 5}, {'year': 2014, 'cited_by_count': 3}, {'year': 2013, 'cited_by_count': 9}, {'year': 2012, 'cited_by_count': 9}], 'updated_date': '2024-12-13T16:17:42.748422', 'created_date': '2016-06-24'}