Publication Information

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425, 445, 457, 467, 485, 505, 517, 527, 3042], 'of': [72, 86, 92, 97, 104, 114, 132, 146, 152, 157, 164, 174, 190, 204, 210, 215, 222, 232, 250, 264, 270, 275, 282, 292, 308, 322, 328, 333, 340, 350, 366, 380, 386, 391, 398, 408, 426, 440, 446, 451, 458, 468, 486, 500, 506, 511, 518, 528, 547, 556, 571, 579, 591, 652, 701, 708, 727, 740, 751, 768, 799, 835, 841, 849, 854, 869, 897, 979, 1028, 1041, 1059, 1103, 1113, 1127, 1177, 1255, 1268, 1316, 1343, 1346, 1385, 1401, 1428, 1444, 1494, 1507, 1557, 1577, 1594, 1606, 1612, 1618, 1631, 1640, 1677, 1687, 1716, 1759, 1781, 1818, 1868, 1879, 1914, 1923, 1978, 1983, 1993, 2026, 2031, 2040, 2055, 2061, 2074, 2085, 2116, 2120, 2124, 2173, 2202, 2211, 2220, 2227, 2261, 2371, 2391, 2398, 2408, 2445, 2456, 2476, 2488, 2518, 2564, 2575, 2584, 2588, 2616, 2635, 2666, 2675, 2693, 2740, 2777, 2873, 2909, 2933, 2947, 2965, 2979, 2985, 2998, 3043, 3046, 3080, 3122, 3177, 3210, 3244, 3274, 3319, 3327, 3360, 3587, 3625, 3630, 3651, 3658, 3687, 3694, 3717, 3771, 3808, 3814, 3820, 3853, 3858, 3887, 3942, 3956], 'Cardiology': [73, 133, 191, 251, 309, 367, 427, 487], '(J.L.,': [74, 134, 192, 252, 310, 368, 428, 488], 'R.Z.,': [75, 135, 193, 253, 311, 369, 429, 489], 'S.F.S.,': [76, 136, 194, 254, 312, 370, 430, 490], 'B.L.,': [77, 137, 195, 255, 313, 371, 431, 491], 'E.E.W.),': [78, 138, 196, 256, 314, 372, 432, 492], 'Center': [79, 139, 197, 257, 315, 373, 433, 493], 'for': [80, 140, 198, 258, 316, 374, 434, 494, 662, 675, 718, 766, 804, 996, 1418, 1587, 1835, 1866, 1950, 2248, 2264, 2335, 2356, 2551, 2556, 2696, 2795, 2878, 2884, 3084, 3214, 3278, 3570, 3768, 3889, 3939, 3993], "Women's": [81, 141, 199, 259, 317, 375, 435, 495], 'Health': [82, 99, 142, 159, 200, 217, 260, 277, 318, 335, 376, 393, 436, 453, 496, 513, 3048], 'Research': [83, 143, 201, 261, 319, 377, 437, 497, 3186], '(J.L.),': [84, 144, 202, 262, 320, 378, 438, 498], 'Department': [85, 145, 203, 263, 321, 379, 439, 499], 'Clinical': [87, 147, 205, 265, 323, 381, 441, 501], 'Pharmacy': [88, 148, 206, 266, 324, 382, 442, 502], '(R.L.P.),': [89, 149, 207, 267, 325, 383, 443, 503], 'Infectious': [93, 105, 153, 165, 211, 223, 271, 283, 329, 341, 387, 399, 447, 459, 507, 519], 'Diseases': [94, 154, 212, 272, 330, 388, 448, 508], '(M.L.),': [95, 155, 213, 273, 331, 389, 449, 509], 'University': [96, 156, 214, 274, 332, 390, 450, 510, 3045], 'Colorado': [98, 158, 216, 276, 334, 392, 452, 512, 3047], 'Sciences': [100, 160, 218, 278, 336, 394, 454, 514, 3049], 'Center,': [101, 119, 161, 179, 219, 237, 279, 297, 337, 355, 395, 413, 455, 473, 515, 533, 3050], 'Denver;': [102, 162, 220, 280, 338, 396, 456, 516], 'Diseases,': [106, 166, 224, 284, 342, 400, 460, 520], 'Vanderbilt': [107, 167, 225, 285, 343, 401, 461, 521], 'University,': [108, 168, 226, 286, 344, 402, 462, 522], 'Nashville,': [109, 169, 227, 287, 345, 403, 463, 523], 'Tenn': [110, 170, 228, 288, 346, 404, 464, 524], '(G.G.M.);': [111, 171, 229, 289, 347, 405, 465, 525], 'Cardiology,': [115, 175, 233, 293, 351, 409, 469, 529, 3044], 'Denver': [116, 176, 234, 294, 352, 410, 470, 530], 'VA': [117, 177, 235, 295, 353, 411, 471, 531], 'Denver,': [120, 180, 238, 298, 356, 414, 474, 534, 3056], 'Colo': [121, 181, 239, 299, 357, 415, 475, 535], '(S.F.S.).': [122, 182, 240, 300, 358, 416, 476, 536], ',': [123, 183, 241, 301, 359, 417], 'PageIIRobert': [126], 'PageII': [128], 'ZoltyRonald': [185], 'Zolty': [186], 'ShakarSimon': [244], 'Shakar': [246], 'LeviMarilyn': [303], 'Levi': [304], 'LowesBrian': [361], 'Lowes': [362], 'WolfelEugene': [420], 'Wolfel': [422], 'MillerGeraldine': [480], 'Miller': [482, 3163, 3790, 3909, 4010], 'Originally': [537], 'published4': [538], 'Jan': [539], '2005https://doi.org/10.1161/01.CIR.0000151609.60618.3CCirculation.': [540], '2005;111:113–117Continued': [541], 'improvement': [542], 'long-term': [545, 1660, 3692], 'survival': [546, 1661], 'heart': [548, 643, 666, 688, 752, 815, 828, 836, 887, 921, 989, 1077, 1114, 1223, 1249, 1271, 1306, 1613, 1666, 1681, 1720, 1782, 1898, 1927, 1939, 1955, 2017, 2213, 2301, 2578, 2727, 2748, 2771, 2948, 3092, 3245, 3400, 3434, 3626, 3634, 3817], 'transplant': [549, 644, 667, 689, 753, 816, 888, 922, 971, 990, 1078, 1115, 1224, 1250, 1272, 1307, 1337, 1614, 1667, 1682, 1704, 1721, 1783, 1886, 1928, 1940, 1956, 2018, 2214, 2484, 2911, 2949, 3093, 3128, 3166, 3246, 3449, 3547, 3893, 3936], 'recipients': [550, 592, 690, 754, 889, 972, 991, 1225, 1251, 1273, 1308, 1338, 1784, 1887, 1941, 1957, 2019, 2407, 2485, 2778, 2912, 2950, 3247], 'has': [551, 573, 913, 1197, 1528, 1765, 2007, 2238, 2375, 2416, 2460, 2495, 2902], 'resulted': [552, 574], 'a': [554, 659, 738, 778, 941, 954, 1034, 1057, 1071, 1122, 1425, 1511, 1578, 1581, 1637, 1658, 1697, 1755, 1965, 1981, 2071, 2217, 2332, 2353, 2388, 2457, 2569, 2721, 2870, 2900, 2944, 2986, 3174, 3325, 3402, 3512, 3663, 3821], 'population': [555, 1285, 1967], 'patients': [557, 874, 1457, 1472, 1515, 1705, 1747, 1895, 1989, 2329, 2533, 2546, 2662, 2745, 2846, 2879, 3129, 3548], 'with': [558, 567, 695, 716, 876, 879, 953, 994, 1085, 1094, 1246, 1261, 1377, 1387, 1504, 1532, 1597, 1636, 1657, 1736, 1748, 1838, 1896, 1901, 1964, 2010, 2129, 2216, 2270, 2321, 2359, 2395, 2419, 2486, 2540, 2603, 2669, 2746, 2761, 2785, 2801, 2810, 2920, 3133, 3248, 3322, 3550, 3995], 'prolonged': [559], 'exposure': [560], 'immunosuppressive': [562, 656, 1693, 3131], 'drugs.1': [563], 'This': [564, 2241], 'exposure,': [565], 'coupled': [566], 'increasing': [569, 650], 'age': [570], 'recipients,': [572, 817, 1722, 2215], 'an': [576, 649, 672, 1382, 1832, 2396, 2632, 2930, 3568], 'impressive': [577], 'prevalence': [578, 1630, 1715, 2739, 2932], 'comorbidities': [580], 'these': [582, 630, 1299, 1349, 1456, 1466, 1567, 2174], 'patients.': [583, 4000], 'Indeed,': [584, 1695], 'by': [585, 822, 940, 1145, 1435, 1843, 2734, 3028, 3171], '5': [586, 756, 1788, 2937], 'years': [587, 1789, 1852, 2769, 2917, 2940], 'after': [588, 636, 796, 827, 935, 1065, 1148, 1155, 1790, 1828, 1856, 1872, 2067, 2078, 2096, 2168, 2300, 2530, 2577, 2726, 2759, 2770, 2827, 2863, 2918, 2941, 3364, 3399, 3433, 3466, 3593, 3633, 3660, 3689, 3816], 'transplantation,': [589, 637, 829, 1791, 2531, 2760, 2772, 2919], '95%': [590, 834], 'have': [593, 596, 600, 607, 616, 658, 966, 974, 1193, 1252, 1274, 1424, 1562, 1946, 2352, 2779, 2835, 2869], 'hypertension,': [594], '81%': [595, 1112], 'hyperlipidemia,': [597], '32%': [599, 1611], 'diabetes.1': [601], 'In': [602, 678, 698, 1075, 1394, 2328, 2472, 2545], 'addition,': [603, 2473], '25%': [604, 2908], '50%': [606, 832, 2737], 'coronary': [608, 775, 783, 3123, 3167, 3172, 3859], 'allograft': [609, 3320, 3724, 3775], 'vasculopathy': [610, 3321], '(CAV),': [611], 'up': [613, 2790, 2906], '33%': [615, 1780], 'chronic': [617, 2276], 'renal': [618, 861, 1165, 1664, 1717, 1749, 1799, 1820, 2283, 2592, 2656, 2764, 3250, 3540, 3546, 3661, 3690, 3723, 3744, 3774, 3892], 'insufficiency.2–5': [619], 'As': [620], 'more': [621, 2642], 'drugs': [622, 657, 965, 1350, 1839, 2606, 2651], 'are': [623, 692, 865, 890, 1081, 1098, 1107, 1215, 1302, 1351, 1409, 1450, 1468, 1484, 1601, 1670, 1741, 1812, 1916, 2050, 2098, 2188, 2294, 2309, 2364, 2387, 2535, 2596, 2610, 2751, 2832, 2951, 2959], 'developed': [624, 1767], 'both': [626, 741, 855, 864, 1291, 1663], 'prevent': [627, 1497, 1769, 2325, 2465, 2499, 2839, 2858], 'treat': [629, 2614, 2624], 'problems': [631, 686], 'common': [633, 684, 712, 826, 1756, 2072, 2186, 2297, 2722], 'infectious': [634], 'complications': [635], 'it': [638, 907, 1431, 1521, 1537, 2013], 'is': [639, 669, 732, 736, 747, 764, 806, 825, 843, 871, 908, 931, 938, 1022, 1050, 1068, 1118, 1324, 1397, 1432, 1463, 1510, 1634, 1655, 1754, 1802, 1864, 1888, 2158, 2176, 2244, 2256, 2515, 2560, 2639, 2671, 2690, 2700, 2720, 2731, 2797, 2929, 2982], 'likely': [640, 737, 909, 2952], 'that': [641, 691, 910, 932, 1195, 1372, 1904, 1954, 2855], 'recipient': [645, 668, 923, 1683, 2455, 3181], 'will': [646, 3017], 'be': [647, 1278, 1288, 1478, 1488, 1552, 1909, 1960, 2196, 2345, 2621, 2631, 2680, 2711, 2954], 'taking': [648, 1339, 1473, 2547, 2663, 2955], 'number': [651, 1617, 2946], 'drugs.': [653, 1694, 2957], 'Because': [654, 2594], 'standard': [655, 2024], 'high': [660, 1453, 1629, 1973, 2354, 2401, 2562], 'potential': [661, 1834, 2355, 2695], 'drug–drug': [663, 676, 713, 1595, 1688, 1836, 2357, 2565, 2601, 2646], 'interactions,': [664, 714], 'subject': [670], 'enormous': [673], 'risk': [674, 840, 1345, 1384, 1586, 2172, 2263, 2334, 2563, 2634, 2794, 2872, 3182], 'interactions.': [677], 'this': [679, 702, 728, 1104, 1317, 1607, 1770, 2056, 2372, 2469, 2687, 2980], 'article,': [680], 'we': [681, 704], 'briefly': [682], 'review': [683], 'medical': [685], 'routinely': [693, 1303, 2160, 2310, 2537], 'addressed': [694], 'drug': [696, 981, 1710], 'therapy.': [697, 3966], 'Part': [699, 725, 1101, 1314, 1604, 2053, 2369, 2977, 2983, 2989, 3003, 3015], 'IV': [700, 1102, 1315, 1605, 2054, 2370, 2978, 3016], 'series,': [703], 'provide': [705], 'specific': [706, 1590, 1709], 'details': [707], 'known': [709, 1804], 'important': [710, 1082, 1091, 1553, 1910], 'along': [715, 1900], 'recommendations': [717], 'management.Coronary': [719], 'Allograft': [720], 'VasculopathyCAV': [721], 'was': [722, 1355, 2205, 3026], 'described': [723], 'I': [726, 2990], 'series.': [729, 2373, 2988], 'The': [730, 838, 1266, 1442, 1589, 1822, 2224, 2729, 2793, 3078, 3208, 3272], 'mechanism': [731], 'incompletely': [733], 'understood': [734], 'but': [735, 906, 1389, 2627, 2673, 2803, 2850, 3628], 'consequence': [739], 'immunologic': [742], 'nonimmunologic': [744], 'factors.3': [745], 'CAV': [746, 763, 771, 805], 'present': [748, 1108, 2331], '42%': [750], 'at': [755, 818, 1399, 1411, 1785, 1969, 1980, 2913, 2936], 'years.3': [757], 'After': [758, 2178], 'first': [760, 1157, 2065, 2080, 2094, 2163, 2314, 2822, 2926], 'posttransplantation': [761, 1158, 1170, 1641, 1875, 2182, 2318], 'year,': [762], 'responsible': [765, 1865], '≈20%': [767, 2060], 'all': [769, 1167, 1183, 1869, 2212, 2483], 'deaths.1,6': [770], 'often': [772, 1023, 1055, 2611, 2652], 'involves': [773], 'arteries': [776], 'diffuse': [779], 'fashion,': [780], 'making': [781], 'percutaneous': [782], 'interventions': [784], 'or': [785, 1010, 1240, 1458, 1461, 1546, 1808, 1841, 1861, 2036, 2273, 2306, 2320, 2341, 2449, 2479, 2543, 2549, 3653, 3810, 3896], 'bypass': [786], 'surgery': [787], 'less': [788, 1200], 'effective': [789, 802, 1217, 1763, 1813, 2247, 2712], 'many': [791, 1849, 2774], 'cases.': [792], 'Prognosis': [793], 'remains': [794, 2014], 'poor': [795], 'development': [798, 1126, 1556], 'CAV.7': [800], 'No': [801, 883], 'prevention': [803, 3857], 'available,': [807], 'although': [808, 1199], 'statins': [809, 1256, 1269, 1301, 1408, 1449, 1476, 1519, 1533], 'seem': [810], 'improve': [812], 'prognosis': [813], 'least': [819], 'part': [821], 'ameliorating': [823], 'CAV.8–10HypertensionHypertension': [824], 'occurring': [830, 1871], 'recipients.6,11,12': [837], 'excess': [839], 'hypertension': [842, 870, 1048, 3465, 3544, 3659, 3688, 3772, 3815, 3890], 'attributable': [844], 'primarily': [845, 1341], 'use': [848, 1335, 1878, 2023, 2028, 2039, 2115, 2226, 2475, 2583, 2587], 'calcineurin': [850], 'inhibitors': [851, 1179, 1213, 1807, 2970], '(CIs)': [852], 'because': [853, 1025, 1040, 1342, 1430, 1520, 2692], 'direct': [856], 'effects': [857, 1012, 1044, 1202, 2280], 'associated': [860, 1260, 1635, 1656, 2418], 'insufficiency.13,14': [862], 'Although': [863, 1548], 'CIs,': [866, 1172, 1340, 1625, 1760], 'incidence': [868, 1427, 1443, 1639, 2397], 'lower': [872, 1412, 1426, 2871], 'treated': [875, 3549], 'tacrolimus': [877, 1196, 3960], 'than': [878, 924, 1281, 1413, 1643, 2875], 'cyclosporine': [880, 3134], 'A': [881, 983, 1616, 3552, 3850], '(CSA).15,16': [882], 'randomized': [884, 960, 986, 1187, 1232, 1361, 1560, 1918, 3404, 3823], 'trials': [885, 961, 1233, 1362, 1561, 1919], 'large': [891, 2945], 'enough': [892], 'evaluate': [894], 'effect': [896, 1758, 2964], 'antihypertensive': [898, 911, 964, 1061], 'therapy': [899, 912, 1764, 1925, 3132, 3997], 'on': [900, 1045, 1203, 1257, 1542, 1701, 1890, 2492, 2971, 3362], 'morbidity,': [901], 'mortality,': [902, 1008, 1258, 2394], 'graft': [904, 1544, 3394], 'survival,': [905], 'similar,': [914, 1198], 'if': [915], 'not': [916, 975, 1356, 1433, 1523, 1529, 1707, 1803, 2376, 2851, 3629], 'greater,': [917], 'benefits': [918, 1254, 1267, 1922], 'general': [927, 1284], 'population.': [928, 1421], 'One': [929, 1186, 1369], 'reason': [930], 'blood': [933, 949, 1005, 2512, 3591, 3631, 3957], 'pressure': [934, 950, 1006, 1064, 3592, 3632, 3924], 'cardiac': [936, 1066, 1885, 2864, 2910, 3127, 3365, 3468, 3510, 3594, 3935], 'transplantation': [937, 1067, 1149, 1829, 1857, 2068, 2097, 2169, 2579, 2828], 'characterized': [939], 'disturbed': [942], 'circadian': [943], 'rhythm': [944], 'without': [945], 'normal': [947, 2811], 'nocturnal': [948, 3588], 'fall': [951, 1153], 'greater': [955, 1280], '24-hour': [956], 'hypertensive': [957], 'burden.11,17,18': [958], 'Most': [959, 2816], 'comparing': [962, 1234], 'different': [963], 'been': [967, 1275, 1530, 1766, 2008, 2378, 2417, 2461, 2496, 2836, 2903], 'performed': [968], 'kidney': [970], 'demonstrated': [976, 1194, 1253, 1381], 'superiority': [978], 'any': [980], 'class.19–23': [982], 'small,': [984], 'prospective,': [985, 3822], 'study': [987, 1371, 1391, 3176, 3852], 'compared': [992, 1373, 1531, 1963], 'lisinopril': [993, 3654, 3811], 'diltiazem': [995, 1021, 3809, 3854], '1': [997, 1853, 2522, 2914, 3063], 'year': [998, 2066], 'revealed': [1000], 'no': [1001, 1559, 1762, 1917, 2553, 2701], 'significant': [1002, 2597], 'difference': [1003], 'control,': [1007], 'creatinine,': [1009], 'side': [1011, 2279], 'between': [1013, 1690, 2046, 2703], '2': [1015, 1360, 2524], 'agents.24': [1016], 'Among': [1017], 'calcium': [1018, 1087, 2888, 3740], 'channel': [1019, 1088, 3882], 'blockers,': [1020], 'used': [1024, 1352, 1398, 1410, 1451, 1479, 1650, 2159, 2311, 2612, 2622, 2684], 'its': [1026], 'inhibition': [1027], 'cytochrome': [1029, 1436], 'P450': [1030], '(CYP450)': [1031], '3A4': [1032], 'allows': [1033], 'reduction': [1035], 'CI': [1037], 'dose': [1038, 1417, 1982], 'reported': [1042, 2009, 2788, 2904], 'favorable': [1043], 'VAC.25': [1046], 'Posttransplantation': [1047], 'frequently': [1049], 'difficult': [1051], 'control': [1053, 3941], 'requires': [1056], 'combination': [1058, 1576, 2688], 'several': [1060, 1190], 'agents.24,26': [1062], 'Blood': [1063, 3923], 'sensitive': [1069], 'low': [1072], 'sodium': [1073, 3932, 3943], 'diet.27': [1074], 'recipient,': [1079], 'there': [1080, 1323, 2595, 2628], 'pharmacokinetic': [1083, 2598], 'interactions': [1084, 1093, 1596, 1689, 1837, 2045, 2358, 2566, 2602], 'blockers': [1089, 1811, 3883], 'pharmacodynamic': [1092, 2600], 'ACE': [1095, 1806, 3764], 'inhibitors.': [1096], 'Both': [1097], 'discussed': [1099, 1363, 1602, 2051, 2365, 2640, 2975], 'series.HyperlipidemiaLipid': [1105], 'abnormalities': [1106], '60%': [1110], 'recipients.28–30': [1116], 'Hyperlipidemia': [1117], 'thought': [1119], 'play': [1121], 'role': [1123], 'CAV,': [1128, 1558, 2420], 'cerebrovascular': [1129], 'disease,': [1130, 1899], 'peripheral': [1132], 'vascular': [1133], 'disease.30,31': [1134], 'Characteristically,': [1135], 'total': [1136], 'cholesterol,': [1137, 1139, 1204, 1206], 'LDL': [1138, 1205, 1220], 'apolipoprotein': [1140], 'B,': [1141, 3110, 3203, 3240, 3307, 3309, 3378, 3414, 3795], 'triglycerides': [1143, 1208, 1550], 'increase': [1144], '3': [1146, 1855, 2232, 2885, 2916], 'months': [1147, 2167, 2319, 2826, 2886], 'then': [1151], 'generally': [1152, 1469, 2195, 2257], 'somewhat': [1154], 'year.8,32,33': [1159], 'Immunosuppressive': [1160], 'drugs,': [1161], 'loop': [1162, 2589], 'diuretics,': [1163, 2590], 'insufficiency': [1166, 1718, 1753, 2657, 2765], 'contribute': [1168, 1626], 'hyperlipidemia.30,32,33': [1171], 'prednisone,': [1173], 'target': [1176], 'rapamycin': [1178], 'sirolimus': [1180, 2362], 'everolimus': [1182], 'exacerbate': [1184], 'hyperlipidemia.33,34': [1185], 'trial': [1188], 'nonrandomized': [1191], 'studies': [1192, 1931, 1936, 2853], 'marked,': [1201], 'as': [1209, 1216, 1226, 1327, 1848, 1858, 1972, 1974, 2133, 2267, 2380, 2400, 2402, 2431, 2773, 2775, 2974, 3884], 'CSA.33,35The': [1210], 'HMG-CoA': [1211], 'reductase': [1212], '(statins)': [1214], 'reducing': [1219], 'cholesterol': [1221, 1292], 'nontransplant': [1229, 1420, 1894, 1966, 2845], 'population.8,9': [1230], 'Two': [1231, 2768], 'pravastatin': [1235, 1366, 1378, 1396, 3361], '(20': [1236, 1375], '40': [1238, 1404], 'mg)': [1239, 1245], 'simvastatin': [1241, 1374], '(5': [1242], '20': [1244, 1402], 'placebo': [1247], 'rejection': [1259, 1862], 'hemodynamic': [1262], 'compromise,': [1263], 'CAV.8–10': [1265], 'suggested': [1276], 'even': [1279, 1696, 1968, 2807, 2935], 'may': [1287, 1423, 1551, 1570, 1908, 2344, 2503, 2620, 2710, 2805], 'due': [1289, 3962], 'lowering': [1293, 1565], 'immune': [1295], 'modulating': [1296], 'effects.8,29': [1297], 'data,': [1300], 'prescribed': [1304, 2346], 'according': [1309], 'guidelines': [1311], 'provided': [1312], 'series': [1318], 'other': [1320, 1407, 1440], 'reviews.29': [1321], 'However,': [1322, 1526], 'considerable': [1325], 'controversy': [1326], 'which': [1329, 2001, 2638], 'statin': [1330, 1579, 3996], 'what': [1332], 'doses': [1333, 1400, 1454, 1971, 2025, 2030, 2674, 2831], 'rhabdomyolysis': [1347, 1386, 1429, 1445], 'when': [1348, 1448, 1459, 1649, 2170, 2683, 2829], 'together.': [1353], 'Rhabdomyolysis': [1354, 2006], 'observed': [1357], 'above': [1364], 'using': [1365, 1932, 1942], 'simvastatin.8–10': [1368], 'observational': [1370], 'mg/d)': [1376, 1380, 2890], '(40': [1379], 'increased': [1383, 1714, 1833, 2121, 2262, 2633], 'simvastatin,': [1388], 'another': [1390], 'did': [1392, 1706], 'not.36,37': [1393], 'general,': [1395], 'mg,': [1405], 'whereas': [1406], 'maximally': [1415], 'approved': [1416], 'Pravastatin': [1422], 'metabolized': [1434], 'enzymes': [1437], 'like': [1438], 'statins.38': [1441], 'increases': [1446, 1584], 'substantially': [1447], 'fibrates': [1460], 'niacin': [1462], 'added,': [1464], 'combinations': [1467], 'contraindicated': [1470], 'CIs.29': [1474], 'If': [1475], 'cannot': [1477, 1517], 'bile': [1481, 1499], 'acid': [1482, 1500], 'sequestrants': [1483, 1501], 'prescribed,': [1485], 'care': [1486], 'must': [1487, 2679], 'taken': [1489], 'separate': [1491], 'timing': [1493], 'administration': [1495], 'from': [1502, 2763], 'interfering': [1503], 'absorption': [1506], 'CSA.': [1508], 'Ezetimibe': [1509], 'reasonable': [1512], 'alternative': [1513], 'who': [1516, 2330, 2534], 'tolerate': [1518], 'does': [1522], 'cause': [1524, 2059, 2073, 2390, 2730], 'rhabdomyolysis.': [1525], 'ezetimibe': [1527], 'determine': [1535], 'whether': [1536, 1805, 2016], 'results': [1538, 1830, 1949, 3819], 'equivalent': [1540], 'efficacy': [1541, 3693], 'rejection,': [1543, 2421], 'atherosclerosis,': [1545], 'mortality.': [1547], 'elevated': [1549], 'evaluated': [1563, 2379], 'triglyceride': [1564], 'patients.29': [1568], 'Fibrates': [1569], 'decrease': [1571, 1823], 'CSA': [1572, 1999, 2972], 'levels,': [1573, 2000, 2973], 'fibrate': [1582], 'significantly': [1583, 2682], 'rhabdomyolysis.29': [1588], 'mechanisms': [1591], 'magnitude': [1593], 'lipid-lowering': [1599], 'agents': [1600, 1934, 2042, 2272, 2709], 'series.DiabetesDiabetes': [1608], 'occurs': [1609, 2528, 2819], 'recipients.6': [1615], 'factors,': [1619], 'including': [1620], 'pretransplantation': [1621, 2581, 2738], 'diabetes,': [1622], 'glucocorticoids,': [1623], 'diabetes.39': [1632], 'Tacrolimus': [1633, 3505], 'higher': [1638, 1652, 2029, 2333], 'diabetes': [1642, 1678, 1702], 'CSA,': [1644], 'especially': [1645, 1882, 2385, 2660], 'blacks': [1647], 'doses.40': [1653], 'Diabetes': [1654], 'poorer': [1659], 'recipients.39,41': [1668], 'There': [1669, 2699, 2928, 2958], 'remarkably': [1671], 'few': [1672, 1685], 'data': [1673, 1902], 'about': [1674], 'treatment': [1676, 3657, 3770, 3813, 3886], 'reports': [1686], 'hypoglycemic': [1691], 'recent': [1698], 'consensus': [1699], 'guideline': [1700], 'address': [1708], 'therapy.41': [1711], 'With': [1712, 2082], 'one': [1723], 'would': [1724], 'expect': [1725], 'relative': [1726], 'contraindications': [1727], 'metformin': [1729], 'fluid': [1731], 'retention': [1732], 'weight': [1734], 'gain': [1735], 'thiazolinediones.42': [1738], 'Shorter-acting': [1739], 'sulfonylureas': [1740, 1745], 'preferred': [1742], 'over': [1743], 'longer-acting': [1744], 'insufficiency.Chronic': [1750], 'Renal': [1751], 'InsufficiencyRenal': [1752], 'adverse': [1757], 'problem.': [1771], 'Creatinine': [1772], 'levels': [1773, 3961], '>2': [1774], 'mg/dL': [1775], 'occur': [1776], '24%': [1778, 2403], '4': [1786], '3%': [1793], '8%': [1795], 'ultimately': [1796], 'develop': [1797, 2806], 'end-stage': [1798], 'disease.4,5,43,44': [1800], 'It': [1801], 'angiotensin': [1809], 'receptor': [1810], 'decreasing': [1815], 'progression': [1817], 'CI-induced': [1819], 'disease.': [1821], 'glomular': [1825], 'filtration': [1826], 'rate': [1827, 2219, 3627], 'secreted': [1840], 'eliminated': [1842, 2239], 'kidney.Antiplatelet': [1845], 'TherapyCAV': [1846], 'causes': [1847], 'deaths': [1850, 1870, 2062], 'do': [1859], 'infections': [1860, 2090, 2103, 2128, 2131, 2175, 2187, 2299, 2429], '17%': [1867], 'third': [1874], 'year.6': [1876, 2081], 'Routine': [1877], 'antiplatelet': [1880, 1924, 1933, 2041], 'agents,': [1881], 'aspirin,': [1883, 2027, 2032], 'based': [1889], 'their': [1891], 'utility': [1892], 'ischemic': [1897], 'suggesting': [1903], 'enhanced': [1905, 2268, 2322, 2423], 'platelet': [1906, 1994], 'activity': [1907], 'pathogenesis': [1913], 'CAV.45There': [1915], 'evaluating': [1920], 'recipients.': [1929, 3725, 3776, 3864], 'Animal': [1930], 'human': [1938], 'warfarin': [1943], 'dipyridamole': [1945], 'shown': [1947, 2462, 2497, 2837], 'conflicting': [1948], 'CAV.46–48': [1951], 'Studies': [1952], 'suggest': [1953, 2854], 'appear': [1958, 3018], 'aspirin': [1961, 1970], 'resistant': [1962], '500': [1975], 'mg/d.49': [1976], 'Evaluation': [1977], 'ticlopidine': [1979], '250': [1984], 'mg': [1985], 'BID': [1986], '12': [1988, 2166, 2317, 2825], 'showed': [1990], 'profound': [1991], 'suppression': [1992], 'aggregation.50': [1995], 'Ticlopidine,': [1996], 'however,': [1997], 'decreases': [1998], 'can': [2002, 2194, 2857], 'lead': [2003], 'rejection.50': [2005], 'clopidogrel.51': [2011], 'Currently,': [2012], 'uncertain': [2015], 'should': [2020], 'continue': [2021], 'switch': [2033], 'thienopyridines,': [2035], 'abandon': [2037], 'altogether.': [2043], 'Additional': [2044], 'CIs': [2047, 2360], 'thienopyridines': [2049], 'series.Infection': [2057], 'ProphylaxisInfections': [2058], 'remain': [2070], 'morbidity': [2075, 2392], 'mortality': [2077, 2218, 3398], 'advent': [2084], 'routine': [2086, 2114, 2493, 2510], 'prophylaxis,': [2087, 2203], 'predominant': [2089], 'seen': [2091, 2206, 2923], 'month': [2095], 'nosocomial': [2099], 'bacterial': [2100], 'fungal': [2102, 2298, 2337, 2432], 'related': [2104], 'mechanical': [2106], 'ventilation,': [2107], 'catheters,': [2108], 'surgical': [2111], 'site.': [2112], 'Before': [2113], 'prophylaxis': [2117, 2255, 2539, 2555], 'during': [2118, 2161, 2259], 'periods': [2119], 'immunosuppression,': [2122, 2424], 'reactivation': [2123], 'herpes': [2125, 2151, 2519, 2526, 2557], 'simplex': [2126, 2152, 2520, 2558], 'opportunistic': [2130, 2428], 'such': [2132, 2266, 2430], 'Pneumocystis': [2134], 'jiroveci': [2135, 2198], '(carinii)': [2136], '(PCP),': [2137], 'cytomegalovirus': [2138], '(CMV),': [2139], 'Aspergillus': [2140], 'species,': [2141], 'Nocardia': [2143, 2250], 'species': [2144, 2293], 'were': [2145], 'common.52,53': [2146], 'Prophylaxis': [2147, 2665], 'against': [2148], 'CMV,': [2149, 2386, 2552], 'PCP,': [2150], 'virus,': [2153], 'oral': [2155, 2304, 2326, 2450, 2477], 'candidiasis': [2156], 'now': [2157], '6': [2164, 2181, 2315, 2823], 'high.': [2177], 'initial': [2180], 'months,': [2183], 'most': [2185, 2296, 2921], 'community': [2189], 'acquired,': [2190], 'prophylactic': [2192, 2225, 2242, 2381, 2446], 'antibiotics': [2193], 'discontinued.Pneumocystis': [2197], '(carinii)Before': [2199], 'institution': [2201], 'PCP': [2204, 2265], '9%': [2208], '11%': [2210, 2221], '38%.53': [2223], 'trimethoprim-sulfamethoxazole': [2228], '(1': [2229], 'double-strength': [2230], 'tablet': [2231], '7': [2234], 'times': [2235], 'per': [2236], 'week)': [2237], 'PCP.52,53': [2240], 'regimen': [2243], 'also': [2245], 'highly': [2246], 'preventing': [2249], 'infection': [2251, 2415, 2467], 'toxoplasmosis.': [2253], 'Trimethoprim-sulfamethoxazole': [2254], 'reinstituted': [2258], 'episodes': [2260, 2615, 2922], 'immunosuppression': [2269, 2323], 'antilymphocyte': [2271], 'acute': [2274, 2617, 2625], 'rejection.54': [2277], 'Potential': [2278], 'include': [2281, 2580, 2887], 'rash,': [2282], 'insufficiency,': [2284], 'hyperkalemia,': [2285, 2659], 'bone': [2287, 2441, 2506, 2757, 2812, 2817, 2840, 2859], 'marrow': [2288, 2442, 2507], 'suppression.55Fungal': [2289], 'InfectionsAspergillosis': [2290], 'Candida': [2292], 'transplantation.': [2302, 2728, 3366, 3469, 3595, 3635], 'Nystatin': [2303], 'solution': [2305], 'clotrimazole': [2307], 'troches': [2308], 'candidiasis.': [2327], 'systemic': [2336, 3543], 'infections,': [2338, 2384], 'fluconazole,': [2339, 2349], 'itraconazole,': [2340], 'occasionally': [2342], 'amphotericin-B': [2343], 'prophylactically.': [2347], 'Voriconazole,': [2348], 'itraconazole': [2351], 'detail': [2367, 2643], 'Caspofungin': [2374], 'yet': [2377], 'therapy.Viral': [2382], 'InfectionsViral': [2383], 'major': [2389, 2753], 'CMV': [2399, 2405, 2409, 2414, 2466, 2490], 'IgG-negative': [2406], 'IgG-positive': [2410], 'donor': [2411, 2459, 3179], 'hearts': [2412], '(D+/R−).56': [2413], 'resulting': [2425, 2716], 'additional': [2427, 2554, 2756], 'disease': [2433, 2436, 3125, 3169, 3396, 3861], 'end-organ': [2435], '(eg,': [2437], 'pneumonitis,': [2438], 'retinitis,': [2439], 'involvement).54,56–61': [2443], 'Use': [2444], 'intravenous': [2447, 2480], 'ganciclovir': [2448, 2481, 2548], 'valganciclovir': [2451, 2478, 2550], 'CMV-seronegative': [2454], 'CMV-positive': [2458], 'effectively': [2464], 'high-risk': [2470, 3999], 'population.59,62–64': [2471], 'preemptive': [2474], 'evidence': [2487], 'active': [2489], 'viremia': [2491], 'monitoring': [2494, 2514], 'symptomatic': [2500], 'disease.59,63': [2501], 'Ganciclovir': [2502], 'result': [2504, 2653], 'suppression,': [2508], 'complete': [2511], 'count': [2513], 'required.': [2516], 'Reactivation': [2517], 'virus': [2521, 2559], 'zoster': [2527], 'commonly': [2529], 'so': [2532], 'seropositive': [2536], 'receive': [2538], 'acyclovir,': [2541], 'famciclovir,': [2542], 'valacyclovir.': [2544], 'necessary.GoutThe': [2561], 'makes': [2567], 'gout': [2568, 2576, 2668], 'particularly': [2570], 'vexing': [2571], 'therapeutic': [2572], 'problem.65': [2573], 'Causes': [2574], 'gout,': [2582, 2626], 'CI,': [2585], 'frequent': [2586], 'insufficiency.66': [2593], 'nonsteroidal': [2604], 'anti-inflammatory': [2605, 2650], 'colchicine,': [2608], 'glucocorticoids': [2609], 'gout.': [2618], 'Colchicine': [2619], 'appears': [2629], 'colchicine': [2636], 'myoneuropathy,': [2637], 'interaction': [2647, 2702], 'section.66': [2648], 'Nonsteroidal': [2649], 'worsening': [2655], 'CIs.': [2664, 2767], 'recurrent': [2667], 'allopurinol': [2670, 2676], 'effective,': [2672], 'azathioprine': [2678], 'reduced': [2681], 'together,': [2685], 'usually': [2689], 'avoided': [2691], 'life-threatening': [2697], 'neutropenia.67': [2698], 'mycophenolate': [2704], 'mofetil': [2705], 'allopurinol.': [2707], 'Uricosuric': [2708], 'some': [2714], 'patients.OsteoporosisOsteoporosis': [2715], 'vertebral': [2718, 2786], 'fractures': [2719, 2787, 2796, 2804, 2843, 2862], 'debilitating': [2724], 'problem': [2725], 'multifactorial,': [2732], 'compounded': [2733], 'nearly': [2736], 'osteopenia': [2741], 'osteoporosis': [2743, 2780], 'advanced': [2747], 'failure.68,69': [2749], 'Glucocorticoids': [2750], 'factor': [2754], 'loss': [2758, 2818, 2841, 2860], 'contributions': [2762], '28%': [2776], 'lumbar': [2783], 'spine,': [2784], '30%.70–72': [2792], 'highest': [2798], 'those': [2800, 2809], 'osteoporosis,': [2802], 'density': [2813], 'before': [2814], 'transplantation.71,72': [2815], 'steroid': [2830], 'highest.73': [2833], 'Bisphosphonates': [2834, 2868], 'receiving': [2847, 2880, 3130], 'glucocorticoids.74,75': [2848], 'Several,': [2849], 'all,': [2852], 'bisphosphonates': [2856], 'liver': [2866], 'transplantation.69,76,77': [2867], 'hypercalciuria': [2874], 'calcitriol.77': [2876], 'Recommendations': [2877], '>5': [2881], 'mg/d': [2882], 'prednisone': [2883], '(1500': [2889], 'vitamin': [2892], 'D': [2893], '(800': [2894], 'IU/d),': [2895], 'regular': [2896], 'weight-bearing': [2897], 'exercise,': [2898], 'bisphosphonate.78,79DepressionDepression': [2901], 'year.80': [2927], '18%': [2931], 'depression': [2934], '10': [2939], 'transplantation.81': [2942], 'Thus,': [2943], 'antidepressant': [2956], 'substantial': [2960], 'differences': [2961], 'various': [2966], 'selective': [2967], 'serotonin': [2968], 'reuptake': [2969], 'series.This': [2981], 'III': [2984], '4-part': [2987], 'appeared': [2991, 3005], 'December': [2994, 3008], '14,': [2995], '2004,': [2996, 3010], 'issue': [2997, 3011], 'journal': [3000], '(Circulation.': [3001, 3012], '2004;110:3734–3740);': [3002], 'II': [3004], '21/28,': [3009], '2004;110:3858–3865);': [3013], 'January': [3021], '18,': [3022], '2005,': [3023], 'issue.This': [3024], 'work': [3025], 'supported': [3027], 'Paul': [3030], 'Elisabeth': [3032], 'Merage': [3033], 'Family': [3034], 'Fund': [3035], 'Cardiology.FootnotesCorrespondence': [3037], '4200': [3051], 'E': [3052], 'Ninth': [3053], 'Ave,': [3054], 'B-130,': [3055], 'CO': [3057], '80262.': [3058], 'E-mail': [3059], '[email': [3060], 'protected]': [3061], 'References': [3062], 'Taylor': [3064, 3260], 'DO,': [3065, 3261], 'Edwards': [3066, 3268], 'LB,': [3067, 3269], 'Mohacsi': [3068, 3266], 'PJ,': [3069, 3267], 'Boucek': [3070, 3204, 3264], 'MM,': [3071, 3205, 3265], 'Trulock': [3072, 3262], 'EP,': [3073, 3263], 'Keck': [3074, 3200, 3270], 'BM,': [3075, 3201], 'Hertz': [3076, 3258], 'MI.': [3077], 'registry': [3079, 3273], 'International': [3082, 3212, 3276], 'Society': [3083, 3213, 3277], 'Lung': [3087, 3097, 3190, 3217, 3224, 3281, 3288], 'Transplantation:': [3088, 3218, 3282], 'twentieth': [3089], 'official': [3090, 3220, 3284], 'adult': [3091], 'report—2003.': [3094], 'J': [3095, 3188, 3222, 3286, 3329, 3369, 3452, 3470, 3485, 3826, 3867], 'Transplant.': [3098, 3191, 3225, 3289, 3669, 3969], '2003;': [3099, 3440, 3899, 4004], '22:': [3100], '616–624.CrossrefMedlineGoogle': [3101], 'Scholar2': [3102], 'Uretsky': [3103], 'BF,': [3104], 'Murali': [3105, 3497], 'S,': [3106, 3340, 3498, 3713, 3759, 3761, 3876], 'Reddy': [3107], 'PS,': [3108], 'Rabin': [3109], 'Lee': [3111], 'A,': [3112, 3118, 3354, 3496, 3645, 3675, 3918, 3977], 'Griffith': [3113, 3503], 'BP,': [3114], 'Hardesty': [3115], 'RL,': [3116, 3295, 3494], 'Trento': [3117], 'Bahnson': [3119], 'HT.': [3120], 'Development': [3121], 'artery': [3124, 3168, 3860], 'prednisone.': [3136], 'Circulation.': [3137, 3406, 3439, 3596, 3945], '1987;': [3138, 3638], '76:': [3139], '827–834.CrossrefMedlineGoogle': [3140], 'Scholar3': [3141], 'Costanzo': [3142], 'MR,': [3143, 3147, 3785], 'Naftel': [3144, 3803], 'DC,': [3145, 3311], 'Pritzker': [3146], 'Heilman': [3148], 'JK': [3149], '3rd,': [3150], 'Boehmer': [3151], 'JP,': [3152, 3989], 'Brozena': [3153, 3782], 'SC,': [3154, 3783], 'Dec': [3155], 'GW,': [3156], 'Ventura': [3157, 3460, 3786], 'HO,': [3158, 3461], 'Kirklin': [3159, 3302], 'JK,': [3160, 3303], 'Bourge': [3161, 3316, 3796], 'RC,': [3162, 3445], 'LW.': [3164], 'detected': [3170], 'angiography:': [3173], 'multiinstitutional': [3175], 'preoperative': [3178], 'factors:': [3183], 'Cardiac': [3184, 3448], 'Database.': [3187], '1998;': [3192, 3254, 3558, 3702], '17:': [3193], '744–753.MedlineGoogle': [3194], 'Scholar4': [3195], 'Hosenpud': [3196], 'JD,': [3197], 'Bennett': [3198, 3478], 'LE,': [3199], 'Fiol': [3202], 'Novick': [3206], 'RJ.': [3207, 3447], 'Registry': [3209], 'sixteenth': [3219], 'report—1999.': [3221], '1999;': [3226, 3778, 3970], '18:': [3227], '611–626.CrossrefMedlineGoogle': [3228], 'Scholar5': [3229], 'van': [3230], 'Gelder': [3231], 'T,': [3232], 'Balk': [3233], 'AH,': [3234, 3605], 'Zietse': [3235], 'R,': [3236, 3301, 3534, 3789, 3797, 3799], 'Hesse': [3237], 'C,': [3238, 3526], 'Mochtar': [3239], 'Weimer': [3241], 'W.': [3242], 'Survival': [3243], 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