Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1973313707', 'doi': 'https://doi.org/10.1016/j.toxicon.2007.02.001', 'title': 'Characterization of the neurotoxicity induced by the extract of Magnistipula butayei (Chrysobalanaceae) in rat: Effects of a new natural convulsive agent', 'display_name': 'Characterization of the neurotoxicity induced by the extract of Magnistipula butayei (Chrysobalanaceae) in rat: Effects of a new natural convulsive agent', 'publication_year': 2007, 'publication_date': '2007-06-01', 'ids': {'openalex': 'https://openalex.org/W1973313707', 'doi': 'https://doi.org/10.1016/j.toxicon.2007.02.001', 'mag': '1973313707', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/17395230'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.toxicon.2007.02.001', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S42803210', 'display_name': 'Toxicon', 'issn_l': '0041-0101', 'issn': ['0041-0101', '1879-3150'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5028959754', 'display_name': 'Charles Karangwa', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210087849', 'display_name': 'University of Rwanda', 'ror': 'https://ror.org/00286hs46', 'country_code': 'RW', 'type': 'education', 'lineage': ['https://openalex.org/I4210087849']}, {'id': 'https://openalex.org/I157674565', 'display_name': 'University of Liège', 'ror': 'https://ror.org/00afp2z80', 'country_code': 'BE', 'type': 'education', 'lineage': ['https://openalex.org/I157674565']}], 'countries': ['BE', 'RW'], 'is_corresponding': False, 'raw_author_name': 'Charles Karangwa', 'raw_affiliation_strings': ['Laboratory of Pharmacology and Toxicology, Department of Pharmacy, Faculty of Sciences, National University of Rwanda, BP 117 Butare, Rwanda', 'Natural and Synthetic Drugs Research Center (CPSNS), University of Liege, B-4000 Liege, Belgium'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Pharmacology and Toxicology, Department of Pharmacy, Faculty of Sciences, National University of Rwanda, BP 117 Butare, Rwanda', 'institution_ids': ['https://openalex.org/I4210087849']}, {'raw_affiliation_string': 'Natural and Synthetic Drugs Research Center (CPSNS), University of Liege, B-4000 Liege, Belgium', 'institution_ids': ['https://openalex.org/I157674565']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5035803595', 'display_name': 'Virginie Esters', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I157674565', 'display_name': 'University of Liège', 'ror': 'https://ror.org/00afp2z80', 'country_code': 'BE', 'type': 'education', 'lineage': ['https://openalex.org/I157674565']}], 'countries': ['BE'], 'is_corresponding': False, 'raw_author_name': 'Virginie Esters', 'raw_affiliation_strings': ['Natural and Synthetic Drugs Research Center (CPSNS), University of Liege, B-4000 Liege, Belgium'], 'affiliations': [{'raw_affiliation_string': 'Natural and Synthetic Drugs Research Center (CPSNS), University of Liege, B-4000 Liege, Belgium', 'institution_ids': ['https://openalex.org/I157674565']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5069035635', 'display_name': 'Monique Tits', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I157674565', 'display_name': 'University of Liège', 'ror': 'https://ror.org/00afp2z80', 'country_code': 'BE', 'type': 'education', 'lineage': ['https://openalex.org/I157674565']}], 'countries': ['BE'], 'is_corresponding': False, 'raw_author_name': 'Monique Tits', 'raw_affiliation_strings': ['Natural and Synthetic Drugs Research Center (CPSNS), University of Liege, B-4000 Liege, Belgium'], 'affiliations': [{'raw_affiliation_string': 'Natural and Synthetic Drugs Research Center (CPSNS), University of Liege, B-4000 Liege, Belgium', 'institution_ids': ['https://openalex.org/I157674565']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5085938049', 'display_name': 'Arlette Minet', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I157674565', 'display_name': 'University of Liège', 'ror': 'https://ror.org/00afp2z80', 'country_code': 'BE', 'type': 'education', 'lineage': ['https://openalex.org/I157674565']}], 'countries': ['BE'], 'is_corresponding': False, 'raw_author_name': 'Arlette Minet', 'raw_affiliation_strings': ['Center for Cellular and Molecular Neurobiology (CNCM), University of Liege, B-4000 Liege, Belgium'], 'affiliations': [{'raw_affiliation_string': 'Center for Cellular and Molecular Neurobiology (CNCM), University of Liege, B-4000 Liege, Belgium', 'institution_ids': ['https://openalex.org/I157674565']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5069132792', 'display_name': 'André Boland', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I157674565', 'display_name': 'University of Liège', 'ror': 'https://ror.org/00afp2z80', 'country_code': 'BE', 'type': 'education', 'lineage': ['https://openalex.org/I157674565']}], 'countries': ['BE'], 'is_corresponding': False, 'raw_author_name': 'André Boland', 'raw_affiliation_strings': ['Center for Cellular and Molecular Neurobiology (CNCM), University of Liege, B-4000 Liege, Belgium'], 'affiliations': [{'raw_affiliation_string': 'Center for Cellular and Molecular Neurobiology (CNCM), University of Liege, B-4000 Liege, Belgium', 'institution_ids': ['https://openalex.org/I157674565']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5067308851', 'display_name': 'Vincent Seutin', 'orcid': 'https://orcid.org/0000-0002-8046-8142'}, 'institutions': [{'id': 'https://openalex.org/I157674565', 'display_name': 'University of Liège', 'ror': 'https://ror.org/00afp2z80', 'country_code': 'BE', 'type': 'education', 'lineage': ['https://openalex.org/I157674565']}], 'countries': ['BE'], 'is_corresponding': False, 'raw_author_name': 'Vincent Seutin', 'raw_affiliation_strings': ['Center for Cellular and Molecular Neurobiology (CNCM), University of Liege, B-4000 Liege, Belgium'], 'affiliations': [{'raw_affiliation_string': 'Center for Cellular and Molecular Neurobiology (CNCM), University of Liege, B-4000 Liege, Belgium', 'institution_ids': ['https://openalex.org/I157674565']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5062191535', 'display_name': 'A Noirfalise', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I157674565', 'display_name': 'University of Liège', 'ror': 'https://ror.org/00afp2z80', 'country_code': 'BE', 'type': 'education', 'lineage': ['https://openalex.org/I157674565']}], 'countries': ['BE'], 'is_corresponding': False, 'raw_author_name': 'Alfred Noirfalise', 'raw_affiliation_strings': ['Natural and Synthetic Drugs Research Center (CPSNS), University of Liege, B-4000 Liege, Belgium'], 'affiliations': [{'raw_affiliation_string': 'Natural and Synthetic Drugs Research Center (CPSNS), University of Liege, B-4000 Liege, Belgium', 'institution_ids': ['https://openalex.org/I157674565']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5022031836', 'display_name': 'Luc Angenot', 'orcid': 'https://orcid.org/0000-0001-8097-2915'}, 'institutions': [{'id': 'https://openalex.org/I157674565', 'display_name': 'University of Liège', 'ror': 'https://ror.org/00afp2z80', 'country_code': 'BE', 'type': 'education', 'lineage': ['https://openalex.org/I157674565']}], 'countries': ['BE'], 'is_corresponding': False, 'raw_author_name': 'Luc Angenot', 'raw_affiliation_strings': ['Natural and Synthetic Drugs Research Center (CPSNS), University of Liege, B-4000 Liege, Belgium'], 'affiliations': [{'raw_affiliation_string': 'Natural and Synthetic Drugs Research Center (CPSNS), University of Liege, B-4000 Liege, Belgium', 'institution_ids': ['https://openalex.org/I157674565']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5010621919', 'display_name': 'Thierry Grisar', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I157674565', 'display_name': 'University of Liège', 'ror': 'https://ror.org/00afp2z80', 'country_code': 'BE', 'type': 'education', 'lineage': ['https://openalex.org/I157674565']}], 'countries': ['BE'], 'is_corresponding': False, 'raw_author_name': 'Thierry Grisar', 'raw_affiliation_strings': ['Center for Cellular and Molecular Neurobiology (CNCM), University of Liege, B-4000 Liege, Belgium'], 'affiliations': [{'raw_affiliation_string': 'Center for Cellular and Molecular Neurobiology (CNCM), University of Liege, B-4000 Liege, Belgium', 'institution_ids': ['https://openalex.org/I157674565']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5070371831', 'display_name': 'A. Foidart', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I157674565', 'display_name': 'University of Liège', 'ror': 'https://ror.org/00afp2z80', 'country_code': 'BE', 'type': 'education', 'lineage': ['https://openalex.org/I157674565']}], 'countries': ['BE'], 'is_corresponding': True, 'raw_author_name': 'Agnès Foidart', 'raw_affiliation_strings': ['Center for Cellular and Molecular Neurobiology (CNCM), University of Liege, B-4000 Liege, Belgium'], 'affiliations': [{'raw_affiliation_string': 'Center for Cellular and Molecular Neurobiology (CNCM), University of Liege, B-4000 Liege, Belgium', 'institution_ids': ['https://openalex.org/I157674565']}]}], 'countries_distinct_count': 2, 'institutions_distinct_count': 2, 'corresponding_author_ids': ['https://openalex.org/A5070371831'], 'corresponding_institution_ids': ['https://openalex.org/I157674565'], 'apc_list': {'value': 3090, 'currency': 'USD', 'value_usd': 3090, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.13, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 4, 'citation_normalized_percentile': {'value': 0.444444, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 76, 'max': 78}, 'biblio': {'volume': '49', 'issue': '8', 'first_page': '1109', 'last_page': '1119'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10077', 'display_name': 'Molecular Mechanisms of Synaptic Plasticity and Neurological Disorders', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10077', 'display_name': 'Molecular Mechanisms of Synaptic Plasticity and Neurological Disorders', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10448', 'display_name': 'Neural Mechanisms of Memory Formation and Spatial Navigation', 'score': 0.9946, 'subfield': {'id': 'https://openalex.org/subfields/2805', 'display_name': 'Cognitive Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12891', 'display_name': 'Herbal Medicine for Neurological Disorders', 'score': 0.9935, 'subfield': {'id': 'https://openalex.org/subfields/2707', 'display_name': 'Complementary and alternative medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/convulsant', 'display_name': 'Convulsant', 'score': 0.7000955}, {'id': 'https://openalex.org/keywords/neurotoxicity', 'display_name': 'Neurotoxicity', 'score': 0.50584793}, {'id': 'https://openalex.org/keywords/memory-improvement', 'display_name': 'Memory improvement', 'score': 0.472112}, {'id': 'https://openalex.org/keywords/neurotoxin', 'display_name': 'Neurotoxin', 'score': 0.45717552}], 'concepts': [{'id': 'https://openalex.org/C2778900099', 'wikidata': 'https://www.wikidata.org/wiki/Q5166679', 'display_name': 'Convulsant', 'level': 3, 'score': 0.7000955}, {'id': 'https://openalex.org/C2776464000', 'wikidata': 'https://www.wikidata.org/wiki/Q545787', 'display_name': 'Dentate gyrus', 'level': 3, 'score': 0.6761241}, {'id': 'https://openalex.org/C67018056', 'wikidata': 'https://www.wikidata.org/wiki/Q414896', 'display_name': 'NMDA receptor', 'level': 3, 'score': 0.5856275}, {'id': 'https://openalex.org/C169760540', 'wikidata': 'https://www.wikidata.org/wiki/Q207011', 'display_name': 'Neuroscience', 'level': 1, 'score': 0.5826223}, {'id': 'https://openalex.org/C148762608', 'wikidata': 'https://www.wikidata.org/wiki/Q3748185', 'display_name': 'Hippocampal formation', 'level': 2, 'score': 0.5675792}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.5092176}, {'id': 'https://openalex.org/C2779491297', 'wikidata': 'https://www.wikidata.org/wiki/Q3338704', 'display_name': 'Neurotoxicity', 'level': 3, 'score': 0.50584793}, {'id': 'https://openalex.org/C2778186239', 'wikidata': 'https://www.wikidata.org/wiki/Q41571', 'display_name': 'Epilepsy', 'level': 2, 'score': 0.47120565}, {'id': 'https://openalex.org/C2780358027', 'wikidata': 'https://www.wikidata.org/wiki/Q407752', 'display_name': 'Neurotoxin', 'level': 2, 'score': 0.45717552}, {'id': 'https://openalex.org/C61174792', 'wikidata': 'https://www.wikidata.org/wiki/Q420510', 'display_name': 'Glutamate receptor', 'level': 3, 'score': 0.43728018}, {'id': 'https://openalex.org/C2780648746', 'wikidata': 'https://www.wikidata.org/wiki/Q28208871', 'display_name': 'Glutamatergic', 'level': 4, 'score': 0.41289884}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.3382603}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.33523715}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.32128054}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.22457701}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.1834937}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.17891541}, {'id': 'https://openalex.org/C29730261', 'wikidata': 'https://www.wikidata.org/wiki/Q274160', 'display_name': 'Toxicity', 'level': 2, 'score': 0.1590634}], 'mesh': [{'descriptor_ui': 'D045469', 'descriptor_name': 'Chrysobalanaceae', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D003292', 'descriptor_name': 'Convulsants', 'qualifier_ui': 'Q000633', 'qualifier_name': 'toxicity', 'is_major_topic': True}, {'descriptor_ui': 'D004830', 'descriptor_name': 'Epilepsy, Tonic-Clonic', 'qualifier_ui': 'Q000139', 'qualifier_name': 'chemically induced', 'is_major_topic': True}, {'descriptor_ui': 'D009498', 'descriptor_name': 'Neurotoxins', 'qualifier_ui': 'Q000633', 'qualifier_name': 'toxicity', 'is_major_topic': True}, {'descriptor_ui': 'D010936', 'descriptor_name': 'Plant Extracts', 'qualifier_ui': 'Q000633', 'qualifier_name': 'toxicity', 'is_major_topic': True}, {'descriptor_ui': 'D000704', 'descriptor_name': 'Analysis of Variance', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D045469', 'descriptor_name': 'Chrysobalanaceae', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003292', 'descriptor_name': 'Convulsants', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': False}, {'descriptor_ui': 'D003292', 'descriptor_name': 'Convulsants', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016291', 'descriptor_name': 'Dizocilpine Maleate', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D016291', 'descriptor_name': 'Dizocilpine Maleate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004569', 'descriptor_name': 'Electroencephalography', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D004569', 'descriptor_name': 'Electroencephalography', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004830', 'descriptor_name': 'Epilepsy, Tonic-Clonic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006624', 'descriptor_name': 'Hippocampus', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D006624', 'descriptor_name': 'Hippocampus', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D006624', 'descriptor_name': 'Hippocampus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007150', 'descriptor_name': 'Immunohistochemistry', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009498', 'descriptor_name': 'Neurotoxins', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': False}, {'descriptor_ui': 'D009498', 'descriptor_name': 'Neurotoxins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010936', 'descriptor_name': 'Plant Extracts', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': False}, {'descriptor_ui': 'D010936', 'descriptor_name': 'Plant Extracts', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016760', 'descriptor_name': 'Proto-Oncogene Proteins c-fos', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D016760', 'descriptor_name': 'Proto-Oncogene Proteins c-fos', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017208', 'descriptor_name': 'Rats, Wistar', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016194', 'descriptor_name': 'Receptors, N-Methyl-D-Aspartate', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': False}, {'descriptor_ui': 'D016194', 'descriptor_name': 'Receptors, N-Methyl-D-Aspartate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.toxicon.2007.02.001', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S42803210', 'display_name': 'Toxicon', 'issn_l': '0041-0101', 'issn': ['0041-0101', '1879-3150'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/17395230', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.76}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 49, 'referenced_works': ['https://openalex.org/W111576738', 'https://openalex.org/W124713771', 'https://openalex.org/W133907179', 'https://openalex.org/W1507242444', 'https://openalex.org/W1567544633', 'https://openalex.org/W1797972710', 'https://openalex.org/W1964809668', 'https://openalex.org/W1968537977', 'https://openalex.org/W1971959365', 'https://openalex.org/W1979501497', 'https://openalex.org/W1982970975', 'https://openalex.org/W1987672715', 'https://openalex.org/W1990651778', 'https://openalex.org/W1999494548', 'https://openalex.org/W2003102216', 'https://openalex.org/W2008243276', 'https://openalex.org/W2015469236', 'https://openalex.org/W2022042292', 'https://openalex.org/W2032520251', 'https://openalex.org/W2035252062', 'https://openalex.org/W2040664100', 'https://openalex.org/W2049592463', 'https://openalex.org/W2051406514', 'https://openalex.org/W2059223526', 'https://openalex.org/W2059433193', 'https://openalex.org/W2060969086', 'https://openalex.org/W2068665404', 'https://openalex.org/W2068709893', 'https://openalex.org/W2069737416', 'https://openalex.org/W2073160869', 'https://openalex.org/W2074780489', 'https://openalex.org/W2080125844', 'https://openalex.org/W2083067374', 'https://openalex.org/W2085251042', 'https://openalex.org/W2086888047', 'https://openalex.org/W2092700031', 'https://openalex.org/W2093238337', 'https://openalex.org/W2095726283', 'https://openalex.org/W2103946141', 'https://openalex.org/W2110456340', 'https://openalex.org/W2113659468', 'https://openalex.org/W2135200619', 'https://openalex.org/W2136597888', 'https://openalex.org/W2168367599', 'https://openalex.org/W2269495432', 'https://openalex.org/W2272773344', 'https://openalex.org/W4206296617', 'https://openalex.org/W570073536', 'https://openalex.org/W643218622'], 'related_works': ['https://openalex.org/W3047019626', 'https://openalex.org/W2421860156', 'https://openalex.org/W2365195844', 'https://openalex.org/W2362632522', 'https://openalex.org/W2091904929', 'https://openalex.org/W2091903688', 'https://openalex.org/W2073081959', 'https://openalex.org/W2029087402', 'https://openalex.org/W2026410709', 'https://openalex.org/W1993348489'], 'abstract_inverted_index': {'This': [0, 123], 'study': [1, 178], 'was': [2, 92], 'designed': [3], 'to': [4, 21, 77, 89, 137, 195], 'document': [5], 'convulsant': [6, 205], 'and': [7, 20, 35, 65, 72, 110, 114, 118, 161, 193], 'neurotoxic': [8, 189], 'properties': [9], 'of': [10, 12, 25, 45, 49, 130, 143, 158], 'extracts': [11], 'a': [13, 183, 187, 196], 'tropical': [14], 'tree,': [15], 'Magnistipula': [16, 50], 'butayei': [17], 'subsp.': [18], 'Montana,': [19], 'investigate': [22], 'the': [23, 26, 95, 107, 128, 133, 156], 'involvement': [24], 'glutamatergic': [27], 'system': [28], 'in': [29, 52, 79, 106, 111, 140, 151, 167, 191], 'these': [30], 'effects.': [31], 'Continuous': [32], 'behavioral': [33, 58], 'observations': [34], 'electroencephalographic': [36], '(EEG)': [37], 'records': [38], 'were': [39, 169], 'obtained': [40], 'after': [41, 121], 'per': [42], 'os': [43], 'administration': [44], 'an': [46, 102, 173, 203], 'aqueous': [47], 'extract': [48], '(MBMAE)': [51], 'rats.': [53], 'MBMAE': [54, 134, 146, 166, 181], '(800': [55], 'mg/kg)': [56], 'induced': [57, 164], 'changes': [59], 'resembling': [60], 'motor': [61], 'limbic': [62], 'seizures:': [63], 'staring': [64], 'head': [66], 'tremor,': [67], 'automatisms,': [68], 'forelimb': [69], 'clonic': [70], 'movements': [71], 'violent': [73], 'tonic-clonic': [74], 'seizures': [75], 'leading': [76], 'death': [78, 149], 'all': [80], 'animals.': [81], 'Concomitantly,': [82], 'important': [83], 'seizure': [84], 'activity': [85, 91, 160, 190], 'that': [86, 127, 138, 180, 200], 'gradually': [87], 'evolved': [88], 'epileptiform': [90], 'recorded': [93], 'on': [94], 'EEG.': [96], 'Moreover,': [97], 'c-Fos': [98, 104], 'immunohistochemistry': [99], 'has': [100], 'revealed': [101], 'increased': [103, 147], 'expression': [105, 124], 'dentate': [108], 'gyrus': [109], 'piriform,': [112], 'peri-': [113], 'entorhinal': [115], 'cortices': [116], '2': [117], '4': [119], 'h': [120], 'treatment.': [122], 'pattern': [125], 'suggested': [126], 'mechanism': [129], 'action': [131], 'for': [132], 'is': [135], 'similar': [136], 'observed': [139], 'glutamate-induced': [141], 'models': [142], 'epilepsy.': [144], 'The': [145], 'cell': [148, 153], 'also': [150], 'hippocampal': [152], 'cultures.': [154], 'Furthermore,': [155], 'build-up': [157], 'convulsive': [159], 'epileptic': [162], 'discharges': [163], 'by': [165, 171], 'rat': [168], 'abolished': [170], 'MK-801,': [172], 'NMDA': [174], 'receptor': [175], 'antagonist.': [176], 'Our': [177], 'suggests': [179], 'contains': [182], 'potent': [184], 'toxin,': [185], 'with': [186], 'powerful': [188], 'rat,': [192], 'corresponding': [194], 'new': [197], 'natural': [198], 'component(s)': [199], 'act': [201], 'as': [202], 'NMDA-mediated': [204], 'molecule.': [206]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1973313707', 'counts_by_year': [{'year': 2017, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-08-15T01:12:16.409138', 'created_date': '2016-06-24'}