Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1973059210', 'doi': 'https://doi.org/10.5402/2012/751768', 'title': 'Ehlers-Danlos Syndrome, Hypermobility Type: An Underdiagnosed Hereditary Connective Tissue Disorder with Mucocutaneous, Articular, and Systemic Manifestations', 'display_name': 'Ehlers-Danlos Syndrome, Hypermobility Type: An Underdiagnosed Hereditary Connective Tissue Disorder with Mucocutaneous, Articular, and Systemic Manifestations', 'publication_year': 2012, 'publication_date': '2012-11-22', 'ids': {'openalex': 'https://openalex.org/W1973059210', 'doi': 'https://doi.org/10.5402/2012/751768', 'mag': '1973059210', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/23227356', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/3512326'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.5402/2012/751768', 'pdf_url': 'https://downloads.hindawi.com/archive/2012/751768.pdf', 'source': {'id': 'https://openalex.org/S4210181468', 'display_name': 'ISRN Dermatology', 'issn_l': '2090-4592', 'issn': ['2090-4592', '2090-4606'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319869', 'host_organization_name': 'Hindawi Publishing Corporation', 'host_organization_lineage': ['https://openalex.org/P4310319869'], 'host_organization_lineage_names': ['Hindawi Publishing Corporation'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://downloads.hindawi.com/archive/2012/751768.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5038724562', 'display_name': 'Marco Castori', 'orcid': 'https://orcid.org/0000-0002-6069-0993'}, 'institutions': [], 'countries': ['IT'], 'is_corresponding': True, 'raw_author_name': 'Marco Castori', 'raw_affiliation_strings': ['Division of Medical Genetics, Department of Molecular Medicine, San Camillo-Forlanini Hospital, Sapienza University, Circonvallazione Gianicolense, 87, 00152 Rome, Italy.'], 'affiliations': [{'raw_affiliation_string': 'Division of Medical Genetics, Department of Molecular Medicine, San Camillo-Forlanini Hospital, Sapienza University, Circonvallazione Gianicolense, 87, 00152 Rome, Italy.', 'institution_ids': []}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 0, 'corresponding_author_ids': ['https://openalex.org/A5038724562'], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 7.679, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 196, 'citation_normalized_percentile': {'value': 0.929854, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '2012', 'issue': None, 'first_page': '1', 'last_page': '22'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11310', 'display_name': 'Connective tissue disorders research', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11310', 'display_name': 'Connective tissue disorders research', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T13313', 'display_name': "Dupuytren's Contracture and Treatments", 'score': 0.9935, 'subfield': {'id': 'https://openalex.org/subfields/2745', 'display_name': 'Rheumatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12924', 'display_name': 'Dermatological and Skeletal Disorders', 'score': 0.9905, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/joint-hypermobility', 'display_name': 'Joint hypermobility', 'score': 0.8476711}, {'id': 'https://openalex.org/keywords/connective-tissue-disorder', 'display_name': 'Connective Tissue Disorder', 'score': 0.77292144}, {'id': 'https://openalex.org/keywords/ehlers–danlos-syndrome', 'display_name': 'Ehlers–Danlos syndrome', 'score': 0.76973045}, {'id': 'https://openalex.org/keywords/hypermobility', 'display_name': 'Hypermobility (travel)', 'score': 0.6625901}, {'id': 'https://openalex.org/keywords/mucocutaneous-zone', 'display_name': 'Mucocutaneous zone', 'score': 0.5652861}], 'concepts': [{'id': 'https://openalex.org/C2781191397', 'wikidata': 'https://www.wikidata.org/wiki/Q1641042', 'display_name': 'Joint hypermobility', 'level': 2, 'score': 0.8476711}, {'id': 'https://openalex.org/C2910325231', 'wikidata': 'https://www.wikidata.org/wiki/Q1779300', 'display_name': 'Connective Tissue Disorder', 'level': 2, 'score': 0.77292144}, {'id': 'https://openalex.org/C2778333328', 'wikidata': 'https://www.wikidata.org/wiki/Q1141499', 'display_name': 'Ehlers–Danlos syndrome', 'level': 2, 'score': 0.76973045}, {'id': 'https://openalex.org/C16005928', 'wikidata': 'https://www.wikidata.org/wiki/Q171171', 'display_name': 'Dermatology', 'level': 1, 'score': 0.73572004}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.7202389}, {'id': 'https://openalex.org/C2777996610', 'wikidata': 'https://www.wikidata.org/wiki/Q5958331', 'display_name': 'Hypermobility (travel)', 'level': 2, 'score': 0.6625901}, {'id': 'https://openalex.org/C156662089', 'wikidata': 'https://www.wikidata.org/wiki/Q6931223', 'display_name': 'Mucocutaneous zone', 'level': 3, 'score': 0.5652861}, {'id': 'https://openalex.org/C518705261', 'wikidata': 'https://www.wikidata.org/wiki/Q25615', 'display_name': 'Connective tissue', 'level': 2, 'score': 0.5163997}, {'id': 'https://openalex.org/C2779134260', 'wikidata': 'https://www.wikidata.org/wiki/Q12136', 'display_name': 'Disease', 'level': 2, 'score': 0.3961763}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.3561022}, {'id': 'https://openalex.org/C1862650', 'wikidata': 'https://www.wikidata.org/wiki/Q186005', 'display_name': 'Physical therapy', 'level': 1, 'score': 0.14294752}], 'mesh': [], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.5402/2012/751768', 'pdf_url': 'https://downloads.hindawi.com/archive/2012/751768.pdf', 'source': {'id': 'https://openalex.org/S4210181468', 'display_name': 'ISRN Dermatology', 'issn_l': '2090-4592', 'issn': ['2090-4592', '2090-4606'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319869', 'host_organization_name': 'Hindawi Publishing Corporation', 'host_organization_lineage': ['https://openalex.org/P4310319869'], 'host_organization_lineage_names': ['Hindawi Publishing Corporation'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc3512326', 'pdf_url': 'https://europepmc.org/articles/pmc3512326?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3512326', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/23227356', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.5402/2012/751768', 'pdf_url': 'https://downloads.hindawi.com/archive/2012/751768.pdf', 'source': {'id': 'https://openalex.org/S4210181468', 'display_name': 'ISRN Dermatology', 'issn_l': '2090-4592', 'issn': ['2090-4592', '2090-4606'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319869', 'host_organization_name': 'Hindawi Publishing Corporation', 'host_organization_lineage': ['https://openalex.org/P4310319869'], 'host_organization_lineage_names': ['Hindawi Publishing Corporation'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.81, 'id': 'https://metadata.un.org/sdg/1', 'display_name': 'No poverty'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 160, 'referenced_works': ['https://openalex.org/W124004656', 'https://openalex.org/W126198151', 'https://openalex.org/W1531218076', 'https://openalex.org/W1557703765', 'https://openalex.org/W1602261019', 'https://openalex.org/W1791830240', 'https://openalex.org/W181858470', 'https://openalex.org/W1835145432', 'https://openalex.org/W1945820448', 'https://openalex.org/W1955777007', 'https://openalex.org/W1963958437', 'https://openalex.org/W1965371993', 'https://openalex.org/W1965512739', 'https://openalex.org/W1965700989', 'https://openalex.org/W1970232553', 'https://openalex.org/W1970448169', 'https://openalex.org/W1974193552', 'https://openalex.org/W1975983438', 'https://openalex.org/W1976449127', 'https://openalex.org/W1977948966', 'https://openalex.org/W1978342229', 'https://openalex.org/W1980313193', 'https://openalex.org/W1983256487', 'https://openalex.org/W1984751116', 'https://openalex.org/W1985002104', 'https://openalex.org/W1985413457', 'https://openalex.org/W1986521012', 'https://openalex.org/W1987478473', 'https://openalex.org/W1988535157', 'https://openalex.org/W1989314103', 'https://openalex.org/W1989696897', 'https://openalex.org/W1992733238', 'https://openalex.org/W1992882474', 'https://openalex.org/W1998906297', 'https://openalex.org/W2002612721', 'https://openalex.org/W2003376740', 'https://openalex.org/W2005062689', 'https://openalex.org/W2009380552', 'https://openalex.org/W2013124058', 'https://openalex.org/W2015846758', 'https://openalex.org/W2016709779', 'https://openalex.org/W2016884542', 'https://openalex.org/W2018503624', 'https://openalex.org/W2019252616', 'https://openalex.org/W2022056302', 'https://openalex.org/W2022790525', 'https://openalex.org/W2023404533', 'https://openalex.org/W2024630318', 'https://openalex.org/W2025422100', 'https://openalex.org/W2026652889', 'https://openalex.org/W2027680256', 'https://openalex.org/W2028431301', 'https://openalex.org/W2029651690', 'https://openalex.org/W2031225542', 'https://openalex.org/W2031748000', 'https://openalex.org/W2033264013', 'https://openalex.org/W2033706886', 'https://openalex.org/W2033921066', 'https://openalex.org/W2034854893', 'https://openalex.org/W2040119803', 'https://openalex.org/W2040303634', 'https://openalex.org/W2042862621', 'https://openalex.org/W2043056729', 'https://openalex.org/W2045359596', 'https://openalex.org/W2046338893', 'https://openalex.org/W2047097737', 'https://openalex.org/W2048227541', 'https://openalex.org/W2048862903', 'https://openalex.org/W2050281754', 'https://openalex.org/W2054155995', 'https://openalex.org/W2055087108', 'https://openalex.org/W2061570671', 'https://openalex.org/W2062883987', 'https://openalex.org/W2063648382', 'https://openalex.org/W2069356098', 'https://openalex.org/W2070957497', 'https://openalex.org/W2071227713', 'https://openalex.org/W2073511622', 'https://openalex.org/W2074241779', 'https://openalex.org/W2074619878', 'https://openalex.org/W2074781730', 'https://openalex.org/W2075489455', 'https://openalex.org/W2076727678', 'https://openalex.org/W2077637924', 'https://openalex.org/W2078598178', 'https://openalex.org/W2081172215', 'https://openalex.org/W2082644907', 'https://openalex.org/W2082910587', 'https://openalex.org/W2083638539', 'https://openalex.org/W2090692747', 'https://openalex.org/W2090823800', 'https://openalex.org/W2092329031', 'https://openalex.org/W2092877017', 'https://openalex.org/W2093120626', 'https://openalex.org/W2094815411', 'https://openalex.org/W2095252600', 'https://openalex.org/W2097224637', 'https://openalex.org/W2100348335', 'https://openalex.org/W2102302711', 'https://openalex.org/W2102837902', 'https://openalex.org/W2104058231', 'https://openalex.org/W2111225988', 'https://openalex.org/W2112474407', 'https://openalex.org/W2113020453', 'https://openalex.org/W2113301042', 'https://openalex.org/W2116566243', 'https://openalex.org/W2119208444', 'https://openalex.org/W2119621114', 'https://openalex.org/W2125035146', 'https://openalex.org/W2125884842', 'https://openalex.org/W2126389560', 'https://openalex.org/W2126412693', 'https://openalex.org/W2126664909', 'https://openalex.org/W2126892836', 'https://openalex.org/W2127777682', 'https://openalex.org/W2128760276', 'https://openalex.org/W2130593575', 'https://openalex.org/W2131252720', 'https://openalex.org/W2135195308', 'https://openalex.org/W2136201571', 'https://openalex.org/W2136519125', 'https://openalex.org/W2136949003', 'https://openalex.org/W2138308270', 'https://openalex.org/W2140706244', 'https://openalex.org/W2142983124', 'https://openalex.org/W2144762638', 'https://openalex.org/W2144908450', 'https://openalex.org/W2150435219', 'https://openalex.org/W2151327480', 'https://openalex.org/W2151691744', 'https://openalex.org/W2152040282', 'https://openalex.org/W2152518735', 'https://openalex.org/W2153707891', 'https://openalex.org/W2154237868', 'https://openalex.org/W2156286274', 'https://openalex.org/W2159052664', 'https://openalex.org/W2159999234', 'https://openalex.org/W2161833484', 'https://openalex.org/W2164201770', 'https://openalex.org/W2164247341', 'https://openalex.org/W2164770300', 'https://openalex.org/W2165044760', 'https://openalex.org/W2166182434', 'https://openalex.org/W2169637232', 'https://openalex.org/W2170138712', 'https://openalex.org/W2171550610', 'https://openalex.org/W2171733218', 'https://openalex.org/W2296680053', 'https://openalex.org/W2313594428', 'https://openalex.org/W2317451245', 'https://openalex.org/W2327706655', 'https://openalex.org/W2344307377', 'https://openalex.org/W2395992348', 'https://openalex.org/W2410277375', 'https://openalex.org/W2418670973', 'https://openalex.org/W2460041742', 'https://openalex.org/W41184717', 'https://openalex.org/W4367363134', 'https://openalex.org/W572268740', 'https://openalex.org/W6637960'], 'related_works': ['https://openalex.org/W3088282304', 'https://openalex.org/W2903752940', 'https://openalex.org/W2886263851', 'https://openalex.org/W2585772542', 'https://openalex.org/W2554211875', 'https://openalex.org/W2550678689', 'https://openalex.org/W2475306778', 'https://openalex.org/W2467498141', 'https://openalex.org/W2290455221', 'https://openalex.org/W1963958437'], 'abstract_inverted_index': {'Ehlers-Danlos': [0], 'syndrome,': [1], 'hypermobility': [2, 15, 102], 'type,': [3], 'constituting': [4], 'a': [5, 35, 47, 87, 141, 167], 'phenotypic': [6], 'continuum': [7], 'with': [8, 38, 50], 'or,': [9, 68], 'perhaps,': [10, 69], 'corresponding': [11], 'to': [12], 'the': [13, 20, 24, 54, 73, 77, 91, 147, 163, 180], 'joint': [14, 101], 'syndrome': [16], '(JHS/EDS-HT),': [17], 'is': [18, 43, 60, 117], 'likely': [19], 'most': [21, 64, 174], 'common,': [22], 'though': [23], 'least': [25], 'recognized,': [26], 'heritable': [27, 160], 'connective': [28, 164], 'tissue': [29, 165], 'disorder.': [30], 'Known': [31], 'for': [32, 146], 'decades': [33, 70], 'as': [34, 46, 140], 'hereditary': [36], 'condition': [37, 59], 'predominant': [39], 'rheumatologic': [40], 'manifestations,': [41, 82, 129], 'it': [42], 'now': [44], 'emerging': [45], 'multisystemic': [48], 'disorder': [49], 'widespread': [51], 'manifestations.': [52], 'Nevertheless,': [53], 'practitioners’': [55], 'awareness': [56], 'of': [57, 80, 144, 162, 170, 175, 182], 'this': [58, 111], 'generally': [61], 'poor': [62], 'and': [63, 84, 103, 133, 136, 166], 'patients': [65], 'await': [66], 'years': [67], 'before': [71], 'reaching': [72], 'correct': [74], 'diagnosis.': [75], 'Among': [76], 'various': [78, 120, 183], 'sites': [79], 'disease': [81], 'skin': [83], 'mucosae': [85], 'represent': [86], 'neglected': [88], 'organ': [89], 'where': [90], 'dermatologist': [92], 'can': [93], 'easily': [94], 'spot': [95], 'diagnostic': [96], 'clues,': [97], 'which': [98], 'consistently': [99], 'integrate': [100], 'other': [104], 'orthopedic/neurologic': [105], 'manifestations': [106], 'at': [107], 'physical': [108], 'examination.': [109], 'In': [110], 'paper,': [112], 'actual': [113], 'knowledge': [114], 'on': [115, 127, 153], 'JHS/EDS-HT': [116], 'summarized': [118], 'in': [119, 179], 'sections.': [121], 'Particular': [122], 'attention': [123], 'has': [124], 'been': [125], 'posed': [126], 'overlooked': [128], 'including': [130], 'cutaneous,': [131], 'mucosal,': [132], 'oropharyngeal': [134], 'features,': [135], 'early': [137], 'diagnosis': [138], 'techniques,': [139], 'major': [142], 'point': [143], 'interest': [145], 'practicing': [148], 'dermatologist.': [149], 'Actual': [150], 'research': [151], 'progresses': [152], 'JH/EDS-HT': [154], 'envisage': [155], 'an': [156], 'unexpected': [157], 'link': [158], 'between': [159], 'dysfunctions': [161], 'wide': [168], 'range': [169], 'functional': [171], 'somatic': [172], 'syndromes,': [173], 'them': [176], 'commonly': [177], 'diagnosed': [178], 'office': [181], 'specialists,': [184], 'comprising': [185], 'dermatologists.': [186]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1973059210', 'counts_by_year': [{'year': 2024, 'cited_by_count': 8}, {'year': 2023, 'cited_by_count': 16}, {'year': 2022, 'cited_by_count': 21}, {'year': 2021, 'cited_by_count': 24}, {'year': 2020, 'cited_by_count': 13}, {'year': 2019, 'cited_by_count': 16}, {'year': 2018, 'cited_by_count': 15}, {'year': 2017, 'cited_by_count': 14}, {'year': 2016, 'cited_by_count': 26}, {'year': 2015, 'cited_by_count': 16}, {'year': 2014, 'cited_by_count': 18}, {'year': 2013, 'cited_by_count': 9}], 'updated_date': '2025-01-13T04:32:42.939009', 'created_date': '2016-06-24'}