Publication Information

{'id': 'https://openalex.org/W1972481641', 'doi': 'https://doi.org/10.1046/j.1365-2230.2001.00898.x', 'title': 'Chronological ageing and photoageing of dendritic cells', 'display_name': 'Chronological ageing and photoageing of dendritic cells', 'publication_year': 2001, 'publication_date': '2001-10-01', 'ids': {'openalex': 'https://openalex.org/W1972481641', 'doi': 'https://doi.org/10.1046/j.1365-2230.2001.00898.x', 'mag': '1972481641', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/11696065'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1046/j.1365-2230.2001.00898.x', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S80252431', 'display_name': 'Clinical and Experimental Dermatology', 'issn_l': '0307-6938', 'issn': ['0307-6938', '1365-2230'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5113544494', 'display_name': 'M. Grewe', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I44260953', 'display_name': 'Heinrich Heine University Düsseldorf', 'ror': 'https://ror.org/024z2rq82', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I44260953']}], 'countries': ['DE'], 'is_corresponding': True, 'raw_author_name': 'M. Grewe', 'raw_affiliation_strings': ['Department of Dermatology, Heinrich‐Heine‐University, Duesseldorf, Germany;'], 'affiliations': [{'raw_affiliation_string': 'Department of Dermatology, Heinrich‐Heine‐University, Duesseldorf, Germany;', 'institution_ids': ['https://openalex.org/I44260953']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5113544494'], 'corresponding_institution_ids': ['https://openalex.org/I44260953'], 'apc_list': None, 'apc_paid': None, 'fwci': 0.386, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 108, 'citation_normalized_percentile': {'value': 0.758592, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '26', 'issue': '7', 'first_page': '608', 'last_page': '612'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10580', 'display_name': 'Immunotherapy and Immune Responses', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10580', 'display_name': 'Immunotherapy and Immune Responses', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10031', 'display_name': 'T-cell and B-cell Immunology', 'score': 0.9978, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11020', 'display_name': 'Immune Cell Function and Interaction', 'score': 0.9953, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/follicular-dendritic-cells', 'display_name': 'Follicular dendritic cells', 'score': 0.45769435}], 'concepts': [{'id': 'https://openalex.org/C8891405', 'wikidata': 'https://www.wikidata.org/wiki/Q1059', 'display_name': 'Immune system', 'level': 2, 'score': 0.8328351}, {'id': 'https://openalex.org/C2778170410', 'wikidata': 'https://www.wikidata.org/wiki/Q506253', 'display_name': 'Dendritic cell', 'level': 3, 'score': 0.6930698}, {'id': 'https://openalex.org/C193419808', 'wikidata': 'https://www.wikidata.org/wiki/Q1645075', 'display_name': 'Acquired immune system', 'level': 3, 'score': 0.63117194}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.5960357}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.53582716}, {'id': 'https://openalex.org/C67662055', 'wikidata': 'https://www.wikidata.org/wiki/Q1047791', 'display_name': 'Antigen-presenting cell', 'level': 4, 'score': 0.5233209}, {'id': 'https://openalex.org/C83464605', 'wikidata': 'https://www.wikidata.org/wiki/Q575296', 'display_name': 'Antigen presentation', 'level': 4, 'score': 0.5229864}, {'id': 'https://openalex.org/C2780849966', 'wikidata': 'https://www.wikidata.org/wiki/Q170758', 'display_name': 'Lymph node', 'level': 2, 'score': 0.5192592}, {'id': 'https://openalex.org/C147483822', 'wikidata': 'https://www.wikidata.org/wiki/Q103537', 'display_name': 'Antigen', 'level': 2, 'score': 0.49391252}, {'id': 'https://openalex.org/C136449434', 'wikidata': 'https://www.wikidata.org/wiki/Q428253', 'display_name': 'Innate immune system', 'level': 3, 'score': 0.48052606}, {'id': 'https://openalex.org/C3753494', 'wikidata': 'https://www.wikidata.org/wiki/Q2631550', 'display_name': 'Follicular dendritic cells', 'level': 5, 'score': 0.45769435}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.4207672}, {'id': 'https://openalex.org/C2776090121', 'wikidata': 'https://www.wikidata.org/wiki/Q193529', 'display_name': 'T cell', 'level': 3, 'score': 0.3576751}], 'mesh': [{'descriptor_ui': 'D003713', 'descriptor_name': 'Dendritic Cells', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D015595', 'descriptor_name': 'Skin Aging', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002452', 'descriptor_name': 'Cell Count', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002478', 'descriptor_name': 'Cells, Cultured', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016922', 'descriptor_name': 'Cellular Senescence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016922', 'descriptor_name': 'Cellular Senescence', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D016207', 'descriptor_name': 'Cytokines', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016207', 'descriptor_name': 'Cytokines', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D003713', 'descriptor_name': 'Dendritic Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003713', 'descriptor_name': 'Dendritic Cells', 'qualifier_ui': 'Q000528', 'qualifier_name': 'radiation effects', 'is_major_topic': False}, {'descriptor_ui': 'D003713', 'descriptor_name': 'Dendritic Cells', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007107', 'descriptor_name': 'Immune System', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007107', 'descriptor_name': 'Immune System', 'qualifier_ui': 'Q000528', 'qualifier_name': 'radiation effects', 'is_major_topic': False}, {'descriptor_ui': 'D007107', 'descriptor_name': 'Immune System', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D007801', 'descriptor_name': 'Langerhans Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007801', 'descriptor_name': 'Langerhans Cells', 'qualifier_ui': 'Q000528', 'qualifier_name': 'radiation effects', 'is_major_topic': False}, {'descriptor_ui': 'D007801', 'descriptor_name': 'Langerhans Cells', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D007801', 'descriptor_name': 'Langerhans Cells', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015595', 'descriptor_name': 'Skin Aging', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014466', 'descriptor_name': 'Ultraviolet Rays', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014466', 'descriptor_name': 'Ultraviolet Rays', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1046/j.1365-2230.2001.00898.x', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S80252431', 'display_name': 'Clinical and Experimental Dermatology', 'issn_l': '0307-6938', 'issn': ['0307-6938', '1365-2230'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/11696065', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.76, 'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 28, 'referenced_works': ['https://openalex.org/W1661544713', 'https://openalex.org/W1733999086', 'https://openalex.org/W1989011133', 'https://openalex.org/W1990818717', 'https://openalex.org/W2005902448', 'https://openalex.org/W2015198907', 'https://openalex.org/W2017929718', 'https://openalex.org/W2038346746', 'https://openalex.org/W2042967546', 'https://openalex.org/W2045912857', 'https://openalex.org/W2052417844', 'https://openalex.org/W2052831326', 'https://openalex.org/W2053784607', 'https://openalex.org/W2057618822', 'https://openalex.org/W2062748240', 'https://openalex.org/W2068239111', 'https://openalex.org/W2071532705', 'https://openalex.org/W2075118572', 'https://openalex.org/W2084749130', 'https://openalex.org/W2088598915', 'https://openalex.org/W2098768339', 'https://openalex.org/W2134660914', 'https://openalex.org/W2148433893', 'https://openalex.org/W2168959535', 'https://openalex.org/W2188294308', 'https://openalex.org/W2405463086', 'https://openalex.org/W2415631813', 'https://openalex.org/W4301965351'], 'related_works': ['https://openalex.org/W619656481', 'https://openalex.org/W31743341', 'https://openalex.org/W3044765367', 'https://openalex.org/W2586380304', 'https://openalex.org/W2415587037', 'https://openalex.org/W2068840909', 'https://openalex.org/W2067868325', 'https://openalex.org/W1976376670', 'https://openalex.org/W1500819482', 'https://openalex.org/W1497187123'], 'abstract_inverted_index': {'Ageing': [0], 'involves': [1], 'the': [2, 6, 18, 24, 33, 38, 56, 59, 69, 91, 165, 201, 217, 221, 225, 261, 324, 328], 'whole': [3], 'organism,': [4], 'including': [5], 'immune': [7, 12, 25, 35, 47, 61, 71, 167, 177, 202], 'system.': [8, 26, 203], 'Age-dependent': [9], 'alterations': [10], 'of': [11, 23, 32, 58, 68, 83, 90, 100, 105, 128, 139, 164, 200, 212, 220, 228, 242, 288, 299, 314, 317, 327], 'functions': [13, 326], 'are': [14, 37, 169, 185, 284], 'located': [15], 'in': [16, 94, 145, 157, 160, 171, 180, 193, 246, 257, 320], 'both': [17], 'adaptive': [19, 60], 'and': [20, 76, 119, 188, 273, 292, 306], 'innate': [21, 34], 'parts': [22], 'The': [27, 240], 'most': [28], 'important': [29], 'cell': [30, 244, 258, 290], 'type': [31], 'system': [36, 168], 'dendritic': [39, 66, 78, 103, 133, 162, 183, 213, 289], 'cells,': [40, 79], 'because': [41], 'their': [42, 146, 172, 255], 'capacity': [43, 147, 174], 'to': [44, 148, 175, 196, 233, 296, 322], 'induce': [45, 149], 'primary': [46], 'responses': [48], 'via': [49], 'professional': [50], 'antigen': [51, 121], 'presentation': [52], 'is': [53, 254, 278], 'crucial': [54], 'for': [55], 'initiation': [57], 'response.': [62], 'Evidence': [63], 'exists': [64], 'that': [65, 156, 280, 293], 'cells': [67, 89, 104, 134, 163, 184, 214, 319], 'systemic': [70, 166], 'system,': [72], 'represented': [73, 86], 'by': [74, 87], 'lymph-node': [75], 'blood-derived': [77], 'as': [80, 82, 248, 250], 'well': [81, 249], 'local': [84], 'immunity,': [85], 'Langerhans': [88, 218, 243, 318], 'skin,': [92, 226], 'participate': [93], 'ageing': [95, 231, 238, 253, 309], 'processes.': [96, 239], 'In': [97, 131, 224, 263], 'animal': [98], 'models': [99], 'older': [101], 'mice,': [102], 'lymph': [106], 'nodes': [107], 'show': [108, 266], 'degenerative': [109], 'characteristics': [110], 'with': [111, 270, 286], 'decreased': [112], 'adhesion': [113], 'molecule': [114], 'expression,': [115], 'less': [116, 271, 274], 'dendrite': [117], 'formation,': [118], 'reduced': [120, 170], 'trapping': [122], 'capacity,': [123], 'which': [124], 'together': [125], 'imply': [126], 'disruption': [127], 'functional': [129, 173], 'activity.': [130], 'contrast,': [132], 'generated': [135, 182], 'from': [136, 236], 'peripheral': [137], 'blood': [138], 'elderly': [140], 'people': [141], 'were': [142], 'not': [143], 'impaired': [144], 'T-cell': [150], 'responses.': [151], 'Together,': [152], 'these': [153, 281, 315], 'findings': [154], 'indicate': [155], 'old': [158], 'individuals': [159], 'vivo': [161], 'stimulate': [176], 'responses,': [178], 'whereas': [179], 'vitro': [181], 'fully': [186], 'functional,': [187], 'therefore': [189], 'might': [190], 'be': [191, 234], 'used': [192], 'therapeutic': [194], 'approaches': [195], 'treat': [197], 'age-associated': [198, 210, 297], 'malfunctions': [199], 'Thus': [204], 'far,': [205], 'only': [206], 'morphological': [207, 282], 'descriptions': [208], 'about': [209], 'changes': [211, 245, 283, 316], '(in': [215], 'particular': [216], 'cells)': [219], 'skin': [222, 252, 300, 308], 'exist.': [223], 'effects': [227], 'naturally': [229], 'occuring': [230], 'have': [232], 'differentiated': [235], 'UV-radiation-induced': [237], 'hallmark': [241], 'natural': [247, 305], 'UV-induced': [251, 307], 'reduction': [256, 313], 'number': [259], 'within': [260], 'epidermis.': [262], 'addition,': [264], 'they': [265], 'an': [267], 'atrophic': [268], 'morphology': [269], 'dendrites,': [272], 'Birbeck': [275], 'granules.': [276], 'It': [277], 'assumed': [279], 'associated': [285], 'loss': [287], 'functions,': [291], 'this': [294], 'contributes': [295], 'development': [298], 'cancer.': [301], 'Therapeutic': [302], 'strategies': [303], 'against': [304], 'should': [310], 'include': [311], 'a': [312], 'order': [321], 'strengthen': [323], 'immunological': [325], "body's": [329], 'outer': [330], 'surface.': [331]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1972481641', 'counts_by_year': [{'year': 2024, 'cited_by_count': 5}, {'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 4}, {'year': 2019, 'cited_by_count': 4}, {'year': 2018, 'cited_by_count': 6}, {'year': 2017, 'cited_by_count': 6}, {'year': 2016, 'cited_by_count': 3}, {'year': 2015, 'cited_by_count': 5}, {'year': 2014, 'cited_by_count': 3}, {'year': 2013, 'cited_by_count': 4}, {'year': 2012, 'cited_by_count': 10}], 'updated_date': '2025-01-06T10:42:52.892169', 'created_date': '2016-06-24'}