Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1970597852', 'doi': 'https://doi.org/10.1093/nar/15.13.5413', 'title': 'Construction of bacteriophage T7 late promoters with point mutations and characterization by<i>in vitro</i>transcription properties', 'display_name': 'Construction of bacteriophage T7 late promoters with point mutations and characterization by<i>in vitro</i>transcription properties', 'publication_year': 1987, 'publication_date': '1987-01-01', 'ids': {'openalex': 'https://openalex.org/W1970597852', 'doi': 'https://doi.org/10.1093/nar/15.13.5413', 'mag': '1970597852', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/3299271', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/305969'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1093/nar/15.13.5413', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S134668137', 'display_name': 'Nucleic Acids Research', 'issn_l': '0305-1048', 'issn': ['0305-1048', '1362-4954', '1362-4962'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://europepmc.org/articles/pmc305969?pdf=render', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5035424712', 'display_name': 'Kenneth A. Chapman', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I135310074', 'display_name': 'University of Wisconsin–Madison', 'ror': 'https://ror.org/01y2jtd41', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I135310074']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Kenneth A. Chapman', 'raw_affiliation_strings': ['McArdle Laboratory for Cancer Research, University of WisconsinMadison, WI 53706, USA'], 'affiliations': [{'raw_affiliation_string': 'McArdle Laboratory for Cancer Research, University of WisconsinMadison, WI 53706, USA', 'institution_ids': ['https://openalex.org/I135310074']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5058731950', 'display_name': 'Richard R. Burgess', 'orcid': 'https://orcid.org/0000-0001-9545-3165'}, 'institutions': [{'id': 'https://openalex.org/I135310074', 'display_name': 'University of Wisconsin–Madison', 'ror': 'https://ror.org/01y2jtd41', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I135310074']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Richard R. Burgess', 'raw_affiliation_strings': ['McArdle Laboratory for Cancer Research, University of WisconsinMadison, WI 53706, USA'], 'affiliations': [{'raw_affiliation_string': 'McArdle Laboratory for Cancer Research, University of WisconsinMadison, WI 53706, USA', 'institution_ids': ['https://openalex.org/I135310074']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3630, 'currency': 'USD', 'value_usd': 3630, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 2.77, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 63, 'citation_normalized_percentile': {'value': 0.908436, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 94, 'max': 95}, 'biblio': {'volume': '15', 'issue': '13', 'first_page': '5413', 'last_page': '5432'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11048', 'display_name': 'Bacteriophages and microbial interactions', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/2303', 'display_name': 'Ecology'}, 'field': {'id': 'https://openalex.org/fields/23', 'display_name': 'Environmental Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11048', 'display_name': 'Bacteriophages and microbial interactions', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/2303', 'display_name': 'Ecology'}, 'field': {'id': 'https://openalex.org/fields/23', 'display_name': 'Environmental Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T10120', 'display_name': 'Bacterial Genetics and Biotechnology', 'score': 0.9985, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10521', 'display_name': 'RNA and protein synthesis mechanisms', 'score': 0.9981, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/transcription', 'display_name': 'Transcription', 'score': 0.619516}], 'concepts': [{'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.949719}, {'id': 'https://openalex.org/C101762097', 'wikidata': 'https://www.wikidata.org/wiki/Q224093', 'display_name': 'Promoter', 'level': 4, 'score': 0.7763829}, {'id': 'https://openalex.org/C2776441376', 'wikidata': 'https://www.wikidata.org/wiki/Q165028', 'display_name': 'Bacteriophage', 'level': 4, 'score': 0.69667137}, {'id': 'https://openalex.org/C176944494', 'wikidata': 'https://www.wikidata.org/wiki/Q1415380', 'display_name': 'Point mutation', 'level': 4, 'score': 0.64521134}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.6412416}, {'id': 'https://openalex.org/C179926584', 'wikidata': 'https://www.wikidata.org/wiki/Q207714', 'display_name': 'Transcription (linguistics)', 'level': 2, 'score': 0.619516}, {'id': 'https://openalex.org/C202751555', 'wikidata': 'https://www.wikidata.org/wiki/Q221681', 'display_name': 'In vitro', 'level': 2, 'score': 0.48604733}, {'id': 'https://openalex.org/C552990157', 'wikidata': 'https://www.wikidata.org/wiki/Q7430', 'display_name': 'DNA', 'level': 2, 'score': 0.4247517}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.36027604}, {'id': 'https://openalex.org/C501734568', 'wikidata': 'https://www.wikidata.org/wiki/Q42918', 'display_name': 'Mutation', 'level': 3, 'score': 0.35959274}, {'id': 'https://openalex.org/C70721500', 'wikidata': 'https://www.wikidata.org/wiki/Q177005', 'display_name': 'Computational biology', 'level': 1, 'score': 0.32076126}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.27955145}, {'id': 'https://openalex.org/C150194340', 'wikidata': 'https://www.wikidata.org/wiki/Q26972', 'display_name': 'Gene expression', 'level': 3, 'score': 0.15030876}, {'id': 'https://openalex.org/C547475151', 'wikidata': 'https://www.wikidata.org/wiki/Q25419', 'display_name': 'Escherichia coli', 'level': 3, 'score': 0.096999735}, {'id': 'https://openalex.org/C41895202', 'wikidata': 'https://www.wikidata.org/wiki/Q8162', 'display_name': 'Linguistics', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C138885662', 'wikidata': 'https://www.wikidata.org/wiki/Q5891', 'display_name': 'Philosophy', 'level': 0, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D004926', 'descriptor_name': 'Escherichia coli', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D009154', 'descriptor_name': 'Mutation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D011401', 'descriptor_name': 'Promoter Regions, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D013604', 'descriptor_name': 'T-Phages', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D014158', 'descriptor_name': 'Transcription, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D003001', 'descriptor_name': 'Cloning, Molecular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012321', 'descriptor_name': 'DNA-Directed RNA Polymerases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D012321', 'descriptor_name': 'DNA-Directed RNA Polymerases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004926', 'descriptor_name': 'Escherichia coli', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009838', 'descriptor_name': 'Oligodeoxyribonucleotides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009994', 'descriptor_name': 'Osmolar Concentration', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010957', 'descriptor_name': 'Plasmids', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011401', 'descriptor_name': 'Promoter Regions, Genetic', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D012965', 'descriptor_name': 'Sodium Chloride', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D012965', 'descriptor_name': 'Sodium Chloride', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013604', 'descriptor_name': 'T-Phages', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013604', 'descriptor_name': 'T-Phages', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1093/nar/15.13.5413', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S134668137', 'display_name': 'Nucleic Acids Research', 'issn_l': '0305-1048', 'issn': ['0305-1048', '1362-4954', '1362-4962'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc305969', 'pdf_url': 'https://europepmc.org/articles/pmc305969?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC305969', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/3299271', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc305969', 'pdf_url': 'https://europepmc.org/articles/pmc305969?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 28, 'referenced_works': ['https://openalex.org/W1487026581', 'https://openalex.org/W1502119192', 'https://openalex.org/W1558516755', 'https://openalex.org/W1568303364', 'https://openalex.org/W1592011518', 'https://openalex.org/W1972323032', 'https://openalex.org/W1986586522', 'https://openalex.org/W2000535151', 'https://openalex.org/W2009787629', 'https://openalex.org/W2014720827', 'https://openalex.org/W2026402107', 'https://openalex.org/W2026898138', 'https://openalex.org/W2026967923', 'https://openalex.org/W2027567110', 'https://openalex.org/W2033063625', 'https://openalex.org/W2052350730', 'https://openalex.org/W2052871796', 'https://openalex.org/W2065723356', 'https://openalex.org/W2065751587', 'https://openalex.org/W2078085951', 'https://openalex.org/W2087014333', 'https://openalex.org/W2088561169', 'https://openalex.org/W2095489470', 'https://openalex.org/W2102154371', 'https://openalex.org/W2138270253', 'https://openalex.org/W4212901177', 'https://openalex.org/W4249954540', 'https://openalex.org/W53735564'], 'related_works': ['https://openalex.org/W3212350425', 'https://openalex.org/W2550943714', 'https://openalex.org/W2511508046', 'https://openalex.org/W2388007221', 'https://openalex.org/W2375287167', 'https://openalex.org/W2363458739', 'https://openalex.org/W2139566393', 'https://openalex.org/W2028961943', 'https://openalex.org/W1994083192', 'https://openalex.org/W1969771092'], 'abstract_inverted_index': {'Journal': [0], 'Article': [1, 97], 'Construction': [2], 'of': [3, 32, 62], 'bacteriophage': [4], 'T7': [5], 'late': [6], 'promoters': [7], 'with': [8], 'point': [9], 'mutations': [10], 'and': [11], 'characterization': [12], 'by': [13, 41, 71], 'in': [14], 'vitro': [15], 'transcription': [16], 'properties': [17], 'Get': [18], 'access': [19], 'Kenneth': [20, 23], 'A.': [21, 24], 'Chapman,': [22], 'Chapman': [25], 'McArdle': [26, 56], 'Laboratory': [27, 57], 'for': [28, 38, 58, 68], 'Cancer': [29, 59], 'Research,': [30, 60, 82], 'University': [31, 61], 'WisconsinMadison,': [33, 63], 'WI': [34, 64], '53706,': [35, 65], 'USA': [36, 66], 'Search': [37, 67], 'other': [39, 69], 'works': [40, 70], 'this': [42, 72], 'author': [43, 73], 'on:': [44, 74], 'Oxford': [45, 75], 'Academic': [46, 76], 'PubMed': [47, 77], 'Google': [48, 78], 'Scholar': [49, 79], 'Richard': [50, 53], 'R.': [51, 54], 'Burgess': [52, 55], 'Nucleic': [80], 'Acids': [81], 'Volume': [83], '15,': [84], 'Issue': [85], '13,': [86], '10': [87, 94, 113], 'July': [88, 95, 114], '1987,': [89], 'Pages': [90], '5413–5432,': [91], 'https://doi.org/10.1093/nar/15.13.5413': [92], 'Published:': [93, 112], '1987': [96, 102, 107, 111, 115], 'history': [98], 'Received:': [99], '22': [100], 'January': [101], 'Revision': [103], 'received:': [104], '04': [105, 109], 'June': [106, 110], 'Accepted:': [108]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1970597852', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2025-01-11T18:26:25.747524', 'created_date': '2016-06-24'}