Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1970486445', 'doi': 'https://doi.org/10.1016/j.cmet.2014.12.006', 'title': 'Potassium Modulates Electrolyte Balance and Blood Pressure through Effects on Distal Cell Voltage and Chloride', 'display_name': 'Potassium Modulates Electrolyte Balance and Blood Pressure through Effects on Distal Cell Voltage and Chloride', 'publication_year': 2015, 'publication_date': '2015-01-01', 'ids': {'openalex': 'https://openalex.org/W1970486445', 'doi': 'https://doi.org/10.1016/j.cmet.2014.12.006', 'mag': '1970486445', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/25565204', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/4332769'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.cmet.2014.12.006', 'pdf_url': 'http://www.cell.com/article/S1550413114005579/pdf', 'source': {'id': 'https://openalex.org/S177533077', 'display_name': 'Cell Metabolism', 'issn_l': '1550-4131', 'issn': ['1550-4131', '1932-7420'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315673', 'host_organization_name': 'Cell Press', 'host_organization_lineage': ['https://openalex.org/P4310320990', 'https://openalex.org/P4310315673'], 'host_organization_lineage_names': ['Elsevier BV', 'Cell Press'], 'type': 'journal'}, 'license': 'publisher-specific-oa', 'license_id': 'https://openalex.org/licenses/publisher-specific-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'hybrid', 'oa_url': 'http://www.cell.com/article/S1550413114005579/pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5055573856', 'display_name': 'Andrew S. Terker', 'orcid': 'https://orcid.org/0000-0003-1498-9043'}, 'institutions': [{'id': 'https://openalex.org/I165690674', 'display_name': 'Oregon Health & Science University', 'ror': 'https://ror.org/009avj582', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I165690674']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Andrew\xa0S. Terker', 'raw_affiliation_strings': ['Division of Nephrology & Hypertension, Department of Medicine, Oregon Health & Science University, Portland, OR 97239, USA'], 'affiliations': [{'raw_affiliation_string': 'Division of Nephrology & Hypertension, Department of Medicine, Oregon Health & Science University, Portland, OR 97239, USA', 'institution_ids': ['https://openalex.org/I165690674']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100393919', 'display_name': 'Chong Zhang', 'orcid': 'https://orcid.org/0000-0002-9353-5359'}, 'institutions': [{'id': 'https://openalex.org/I165690674', 'display_name': 'Oregon Health & Science University', 'ror': 'https://ror.org/009avj582', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I165690674']}, {'id': 'https://openalex.org/I2801518579', 'display_name': 'XinHua Hospital', 'ror': 'https://ror.org/04dzvks42', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2801518579']}, {'id': 'https://openalex.org/I183067930', 'display_name': 'Shanghai Jiao Tong University', 'ror': 'https://ror.org/0220qvk04', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I183067930']}], 'countries': ['CN', 'US'], 'is_corresponding': False, 'raw_author_name': 'Chong Zhang', 'raw_affiliation_strings': ['Department of Nephrology, Xinhua Hostpital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200092, China', 'Division of Nephrology & Hypertension, Department of Medicine, Oregon Health & Science University, Portland, OR 97239, USA'], 'affiliations': [{'raw_affiliation_string': 'Division of Nephrology & Hypertension, Department of Medicine, Oregon Health & Science University, Portland, OR 97239, USA', 'institution_ids': ['https://openalex.org/I165690674']}, {'raw_affiliation_string': 'Department of Nephrology, Xinhua Hostpital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200092, China', 'institution_ids': ['https://openalex.org/I2801518579', 'https://openalex.org/I183067930']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5003885631', 'display_name': 'James A. McCormick', 'orcid': 'https://orcid.org/0000-0003-4000-6653'}, 'institutions': [{'id': 'https://openalex.org/I165690674', 'display_name': 'Oregon Health & Science University', 'ror': 'https://ror.org/009avj582', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I165690674']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'James\xa0A. McCormick', 'raw_affiliation_strings': ['Division of Nephrology & Hypertension, Department of Medicine, Oregon Health & Science University, Portland, OR 97239, USA'], 'affiliations': [{'raw_affiliation_string': 'Division of Nephrology & Hypertension, Department of Medicine, Oregon Health & Science University, Portland, OR 97239, USA', 'institution_ids': ['https://openalex.org/I165690674']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5023852543', 'display_name': 'Rebecca Lazelle', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I165690674', 'display_name': 'Oregon Health & Science University', 'ror': 'https://ror.org/009avj582', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I165690674']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Rebecca\xa0A. Lazelle', 'raw_affiliation_strings': ['Division of Nephrology & Hypertension, Department of Medicine, Oregon Health & Science University, Portland, OR 97239, USA'], 'affiliations': [{'raw_affiliation_string': 'Division of Nephrology & Hypertension, Department of Medicine, Oregon Health & Science University, Portland, OR 97239, USA', 'institution_ids': ['https://openalex.org/I165690674']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5048776453', 'display_name': 'Chengbiao Zhang', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I181190671', 'display_name': 'New York Medical College', 'ror': 'https://ror.org/03dkvy735', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I181190671']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Chengbiao Zhang', 'raw_affiliation_strings': ['Department of Pharmacology, New York Medical College, Valhalla, NY 10595, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmacology, New York Medical College, Valhalla, NY 10595, USA', 'institution_ids': ['https://openalex.org/I181190671']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5088157496', 'display_name': 'Nicholas P. Meermeier', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I165690674', 'display_name': 'Oregon Health & Science University', 'ror': 'https://ror.org/009avj582', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I165690674']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Nicholas\xa0P. Meermeier', 'raw_affiliation_strings': ['Division of Nephrology & Hypertension, Department of Medicine, Oregon Health & Science University, Portland, OR 97239, USA'], 'affiliations': [{'raw_affiliation_string': 'Division of Nephrology & Hypertension, Department of Medicine, Oregon Health & Science University, Portland, OR 97239, USA', 'institution_ids': ['https://openalex.org/I165690674']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5080997505', 'display_name': 'Dominic A. Siler', 'orcid': 'https://orcid.org/0000-0003-4474-6464'}, 'institutions': [{'id': 'https://openalex.org/I165690674', 'display_name': 'Oregon Health & Science University', 'ror': 'https://ror.org/009avj582', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I165690674']}, {'id': 'https://openalex.org/I4210157890', 'display_name': 'Neurological Surgery', 'ror': 'https://ror.org/04r0gp612', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210157890']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Dominic\xa0A. Siler', 'raw_affiliation_strings': ['Department of Neurological Surgery, Oregon Health & Science University, Portland, OR 97239, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Neurological Surgery, Oregon Health & Science University, Portland, OR 97239, USA', 'institution_ids': ['https://openalex.org/I165690674', 'https://openalex.org/I4210157890']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5003751045', 'display_name': 'Hae J. Park', 'orcid': 'https://orcid.org/0000-0001-7768-9297'}, 'institutions': [{'id': 'https://openalex.org/I165690674', 'display_name': 'Oregon Health & Science University', 'ror': 'https://ror.org/009avj582', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I165690674']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Hae\xa0J. Park', 'raw_affiliation_strings': ['Division of Nephrology & Hypertension, Department of Medicine, Oregon Health & Science University, Portland, OR 97239, USA'], 'affiliations': [{'raw_affiliation_string': 'Division of Nephrology & Hypertension, Department of Medicine, Oregon Health & Science University, Portland, OR 97239, USA', 'institution_ids': ['https://openalex.org/I165690674']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5037759253', 'display_name': 'Yi Fu', 'orcid': 'https://orcid.org/0000-0002-8832-9331'}, 'institutions': [{'id': 'https://openalex.org/I165690674', 'display_name': 'Oregon Health & Science University', 'ror': 'https://ror.org/009avj582', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I165690674']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Yi Fu', 'raw_affiliation_strings': ['Division of Nephrology & Hypertension, Department of Medicine, Oregon Health & Science University, Portland, OR 97239, USA'], 'affiliations': [{'raw_affiliation_string': 'Division of Nephrology & Hypertension, Department of Medicine, Oregon Health & Science University, Portland, OR 97239, USA', 'institution_ids': ['https://openalex.org/I165690674']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5085239759', 'display_name': 'David Cohen', 'orcid': 'https://orcid.org/0000-0003-0935-051X'}, 'institutions': [{'id': 'https://openalex.org/I165690674', 'display_name': 'Oregon Health & Science University', 'ror': 'https://ror.org/009avj582', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I165690674']}, {'id': 'https://openalex.org/I4210144745', 'display_name': 'VA Portland Health Care System', 'ror': 'https://ror.org/054484h93', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1322918889', 'https://openalex.org/I2799886695', 'https://openalex.org/I4210144745']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'David\xa0M. Cohen', 'raw_affiliation_strings': ['Division of Nephrology & Hypertension, Department of Medicine, Oregon Health & Science University, Portland, OR 97239, USA', 'VA Portland Health Care System, Portland, OR 97239, USA'], 'affiliations': [{'raw_affiliation_string': 'Division of Nephrology & Hypertension, Department of Medicine, Oregon Health & Science University, Portland, OR 97239, USA', 'institution_ids': ['https://openalex.org/I165690674']}, {'raw_affiliation_string': 'VA Portland Health Care System, Portland, OR 97239, USA', 'institution_ids': ['https://openalex.org/I4210144745']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5061622706', 'display_name': 'Alan M. Weinstein', 'orcid': 'https://orcid.org/0000-0002-3192-1297'}, 'institutions': [{'id': 'https://openalex.org/I4210106287', 'display_name': 'College Medical Center', 'ror': 'https://ror.org/01g9vka88', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210106287']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Alan\xa0M. Weinstein', 'raw_affiliation_strings': ['Department of Physiology and Biophysics, Weil Medical College, New York, NY 10065, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Physiology and Biophysics, Weil Medical College, New York, NY 10065, USA', 'institution_ids': ['https://openalex.org/I4210106287']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5014356601', 'display_name': 'Wen Hui Wang', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I181190671', 'display_name': 'New York Medical College', 'ror': 'https://ror.org/03dkvy735', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I181190671']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Wen-Hui Wang', 'raw_affiliation_strings': ['Department of Pharmacology, New York Medical College, Valhalla, NY 10595, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmacology, New York Medical College, Valhalla, NY 10595, USA', 'institution_ids': ['https://openalex.org/I181190671']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100861807', 'display_name': 'Chao-Ling Yang', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210144745', 'display_name': 'VA Portland Health Care System', 'ror': 'https://ror.org/054484h93', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1322918889', 'https://openalex.org/I2799886695', 'https://openalex.org/I4210144745']}, {'id': 'https://openalex.org/I165690674', 'display_name': 'Oregon Health & Science University', 'ror': 'https://ror.org/009avj582', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I165690674']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Chao-Ling Yang', 'raw_affiliation_strings': ['Division of Nephrology & Hypertension, Department of Medicine, Oregon Health & Science University, Portland, OR 97239, USA', 'VA Portland Health Care System, Portland, OR 97239, USA'], 'affiliations': [{'raw_affiliation_string': 'VA Portland Health Care System, Portland, OR 97239, USA', 'institution_ids': ['https://openalex.org/I4210144745']}, {'raw_affiliation_string': 'Division of Nephrology & Hypertension, Department of Medicine, Oregon Health & Science University, Portland, OR 97239, USA', 'institution_ids': ['https://openalex.org/I165690674']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5041651649', 'display_name': 'David H. Ellison', 'orcid': 'https://orcid.org/0000-0003-2915-265X'}, 'institutions': [{'id': 'https://openalex.org/I4210144745', 'display_name': 'VA Portland Health Care System', 'ror': 'https://ror.org/054484h93', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1322918889', 'https://openalex.org/I2799886695', 'https://openalex.org/I4210144745']}, {'id': 'https://openalex.org/I165690674', 'display_name': 'Oregon Health & Science University', 'ror': 'https://ror.org/009avj582', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I165690674']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'David\xa0H. Ellison', 'raw_affiliation_strings': ['Division of Nephrology & Hypertension, Department of Medicine, Oregon Health & Science University, Portland, OR 97239, USA', 'VA Portland Health Care System, Portland, OR 97239, USA'], 'affiliations': [{'raw_affiliation_string': 'VA Portland Health Care System, Portland, OR 97239, USA', 'institution_ids': ['https://openalex.org/I4210144745']}, {'raw_affiliation_string': 'Division of Nephrology & Hypertension, Department of Medicine, Oregon Health & Science University, Portland, OR 97239, USA', 'institution_ids': ['https://openalex.org/I165690674']}]}], 'countries_distinct_count': 2, 'institutions_distinct_count': 7, 'corresponding_author_ids': ['https://openalex.org/A5041651649'], 'corresponding_institution_ids': ['https://openalex.org/I4210144745', 'https://openalex.org/I165690674'], 'apc_list': {'value': 9080, 'currency': 'USD', 'value_usd': 9080, 'provenance': 'doaj'}, 'apc_paid': {'value': 9080, 'currency': 'USD', 'value_usd': 9080, 'provenance': 'doaj'}, 'fwci': 18.346, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 380, 'citation_normalized_percentile': {'value': 0.999985, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '21', 'issue': '1', 'first_page': '39', 'last_page': '50'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10724', 'display_name': 'Molecular Mechanisms of Aquaporins in Physiology and Disease', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10724', 'display_name': 'Molecular Mechanisms of Aquaporins in Physiology and Disease', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12075', 'display_name': 'Effects of Dietary Sodium on Health', 'score': 0.9989, 'subfield': {'id': 'https://openalex.org/subfields/2916', 'display_name': 'Nutrition and Dietetics'}, 'field': {'id': 'https://openalex.org/fields/29', 'display_name': 'Nursing'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11839', 'display_name': 'Management of Primary Aldosteronism', 'score': 0.9957, 'subfield': {'id': 'https://openalex.org/subfields/2712', 'display_name': 'Endocrinology, Diabetes and Metabolism'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/distal-convoluted-tubule', 'display_name': 'Distal convoluted tubule', 'score': 0.72640795}, {'id': 'https://openalex.org/keywords/homeostasis', 'display_name': 'Homeostasis', 'score': 0.71252257}, {'id': 'https://openalex.org/keywords/pseudohypoaldosteronism', 'display_name': 'Pseudohypoaldosteronism', 'score': 0.5923143}, {'id': 'https://openalex.org/keywords/potassium-intake', 'display_name': 'Potassium Intake', 'score': 0.569864}, {'id': 'https://openalex.org/keywords/sodium-intake', 'display_name': 'Sodium Intake', 'score': 0.532745}, {'id': 'https://openalex.org/keywords/hypertension', 'display_name': 'Hypertension', 'score': 0.51999}], 'concepts': [{'id': 'https://openalex.org/C2776777027', 'wikidata': 'https://www.wikidata.org/wiki/Q2914731', 'display_name': 'Distal convoluted tubule', 'level': 4, 'score': 0.72640795}, {'id': 'https://openalex.org/C63645605', 'wikidata': 'https://www.wikidata.org/wiki/Q103191', 'display_name': 'Homeostasis', 'level': 2, 'score': 0.71252257}, {'id': 'https://openalex.org/C2778525890', 'wikidata': 'https://www.wikidata.org/wiki/Q184564', 'display_name': 'Aldosterone', 'level': 2, 'score': 0.6681402}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.61897206}, {'id': 'https://openalex.org/C517785266', 'wikidata': 'https://www.wikidata.org/wiki/Q703', 'display_name': 'Potassium', 'level': 2, 'score': 0.6066343}, {'id': 'https://openalex.org/C2776273561', 'wikidata': 'https://www.wikidata.org/wiki/Q200745', 'display_name': 'Pseudohypoaldosteronism', 'level': 3, 'score': 0.5923143}, {'id': 'https://openalex.org/C79879829', 'wikidata': 'https://www.wikidata.org/wiki/Q5571762', 'display_name': 'Intracellular', 'level': 2, 'score': 0.55490035}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.551736}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.53543717}, {'id': 'https://openalex.org/C188053792', 'wikidata': 'https://www.wikidata.org/wiki/Q3640664', 'display_name': 'Cotransporter', 'level': 3, 'score': 0.47256655}, {'id': 'https://openalex.org/C537181965', 'wikidata': 'https://www.wikidata.org/wiki/Q658', 'display_name': 'Sodium', 'level': 2, 'score': 0.41668957}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.3664179}, {'id': 'https://openalex.org/C56906281', 'wikidata': 'https://www.wikidata.org/wiki/Q4391435', 'display_name': 'Reabsorption', 'level': 3, 'score': 0.3429112}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.29523847}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.25239664}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.17901906}, {'id': 'https://openalex.org/C2780091579', 'wikidata': 'https://www.wikidata.org/wiki/Q9377', 'display_name': 'Kidney', 'level': 2, 'score': 0.17574435}, {'id': 'https://openalex.org/C178790620', 'wikidata': 'https://www.wikidata.org/wiki/Q11351', 'display_name': 'Organic chemistry', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D001794', 'descriptor_name': 'Blood Pressure', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D004573', 'descriptor_name': 'Electrolytes', 'qualifier_ui': 'Q000652', 'qualifier_name': 'urine', 'is_major_topic': True}, {'descriptor_ui': 'D017419', 'descriptor_name': 'Potassium, Dietary', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002460', 'descriptor_name': 'Cell Line', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002712', 'descriptor_name': 'Chlorides', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007686', 'descriptor_name': 'Kidney Tubules, Distal', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008564', 'descriptor_name': 'Membrane Potentials', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008807', 'descriptor_name': 'Mice, Inbred BALB C', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008810', 'descriptor_name': 'Mice, Inbred C57BL', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018345', 'descriptor_name': 'Mice, Knockout', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015778', 'descriptor_name': 'Minor Histocompatibility Antigens', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011188', 'descriptor_name': 'Potassium', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': False}, {'descriptor_ui': 'D024661', 'descriptor_name': 'Potassium Channels, Inwardly Rectifying', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D017346', 'descriptor_name': 'Protein Serine-Threonine Kinases', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D011546', 'descriptor_name': 'Pseudohypoaldosteronism', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D017673', 'descriptor_name': 'Sodium Chloride, Dietary', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D064486', 'descriptor_name': 'Solute Carrier Family 12, Member 3', 'qualifier_ui': 'Q000172', 'qualifier_name': 'deficiency', 'is_major_topic': False}, {'descriptor_ui': 'D000076204', 'descriptor_name': 'WNK Lysine-Deficient Protein Kinase 1', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.cmet.2014.12.006', 'pdf_url': 'http://www.cell.com/article/S1550413114005579/pdf', 'source': {'id': 'https://openalex.org/S177533077', 'display_name': 'Cell Metabolism', 'issn_l': '1550-4131', 'issn': ['1550-4131', '1932-7420'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315673', 'host_organization_name': 'Cell Press', 'host_organization_lineage': ['https://openalex.org/P4310320990', 'https://openalex.org/P4310315673'], 'host_organization_lineage_names': ['Elsevier BV', 'Cell Press'], 'type': 'journal'}, 'license': 'publisher-specific-oa', 'license_id': 'https://openalex.org/licenses/publisher-specific-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc4332769', 'pdf_url': 'https://europepmc.org/articles/pmc4332769?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332769', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/25565204', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/j.cmet.2014.12.006', 'pdf_url': 'http://www.cell.com/article/S1550413114005579/pdf', 'source': {'id': 'https://openalex.org/S177533077', 'display_name': 'Cell Metabolism', 'issn_l': '1550-4131', 'issn': ['1550-4131', '1932-7420'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315673', 'host_organization_name': 'Cell Press', 'host_organization_lineage': ['https://openalex.org/P4310320990', 'https://openalex.org/P4310315673'], 'host_organization_lineage_names': ['Elsevier BV', 'Cell Press'], 'type': 'journal'}, 'license': 'publisher-specific-oa', 'license_id': 'https://openalex.org/licenses/publisher-specific-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 44, 'referenced_works': ['https://openalex.org/W1443975055', 'https://openalex.org/W1971877828', 'https://openalex.org/W1975016763', 'https://openalex.org/W1976183622', 'https://openalex.org/W1993570453', 'https://openalex.org/W2013369484', 'https://openalex.org/W2015392008', 'https://openalex.org/W2019251722', 'https://openalex.org/W2025950080', 'https://openalex.org/W2027895266', 'https://openalex.org/W2048332551', 'https://openalex.org/W2058574926', 'https://openalex.org/W2058705761', 'https://openalex.org/W2060172930', 'https://openalex.org/W2060271559', 'https://openalex.org/W2066031126', 'https://openalex.org/W2079163382', 'https://openalex.org/W2087144172', 'https://openalex.org/W2089400376', 'https://openalex.org/W2104001407', 'https://openalex.org/W2105851019', 'https://openalex.org/W2106365130', 'https://openalex.org/W2106445408', 'https://openalex.org/W2109726655', 'https://openalex.org/W2113788831', 'https://openalex.org/W2114052164', 'https://openalex.org/W2114870552', 'https://openalex.org/W2116215226', 'https://openalex.org/W2117487052', 'https://openalex.org/W2119240136', 'https://openalex.org/W2127951313', 'https://openalex.org/W2129062330', 'https://openalex.org/W2133138020', 'https://openalex.org/W2135383573', 'https://openalex.org/W2135394966', 'https://openalex.org/W2137895593', 'https://openalex.org/W2141756947', 'https://openalex.org/W2142197398', 'https://openalex.org/W2161168230', 'https://openalex.org/W2167968191', 'https://openalex.org/W2171456074', 'https://openalex.org/W2172151601', 'https://openalex.org/W2321007701', 'https://openalex.org/W2327597239'], 'related_works': ['https://openalex.org/W4315785628', 'https://openalex.org/W3168270741', 'https://openalex.org/W3038202479', 'https://openalex.org/W2337423769', 'https://openalex.org/W2138131441', 'https://openalex.org/W2129314512', 'https://openalex.org/W2081330632', 'https://openalex.org/W1986400814', 'https://openalex.org/W1974696633', 'https://openalex.org/W1948548825'], 'abstract_inverted_index': {'Dietary': [0], 'potassium': [1, 46, 96, 116, 145], 'deficiency,': [2], 'common': [3], 'in': [4, 20, 28, 51, 65, 82, 130, 141], 'modern': [5], 'diets,': [6], 'raises': [7], 'blood': [8, 66, 104], 'pressure': [9], 'and': [10, 62], 'enhances': [11], 'salt': [12, 56], 'sensitivity.': [13], 'Potassium': [14], 'homeostasis': [15], 'requires': [16], 'a': [17, 63], 'molecular': [18], 'switch': [19], 'the': [21, 36, 52, 100, 121, 131], 'distal': [22], 'convoluted': [23], 'tubule': [24], '(DCT),': [25], 'which': [26, 75], 'fails': [27], 'familial': [29], 'hyperkalemic': [30], 'hypertension': [31], '(pseudohypoaldosteronism': [32], 'type': [33], '2),': [34], 'activating': [35], 'thiazide-sensitive': [37], 'NaCl': [38], 'cotransporter,': [39], 'NCC.': [40], 'Here,': [41], 'we': [42], 'show': [43, 108], 'that': [44, 109], 'dietary': [45], 'deficiency': [47], 'activates': [48, 124], 'NCC,': [49, 94], 'even': [50, 98], 'setting': [53], 'of': [54, 102], 'high': [55], 'intake,': [57], 'thereby': [58], 'causing': [59], 'sodium': [60], 'retention': [61], 'rise': [64], 'pressure.': [67, 105], 'The': [68], 'effect': [69], 'is': [70], 'dependent': [71], 'on': [72], 'plasma': [73], 'potassium,': [74], 'modulates': [76], 'DCT': [77, 110], 'cell': [78], 'membrane': [79, 118], 'voltage': [80], 'and,': [81], 'turn,': [83], 'intracellular': [84, 87], 'chloride.': [85], 'Low': [86], 'chloride': [88], 'stimulates': [89], 'WNK': [90, 127], 'kinases': [91], 'to': [92, 143], 'activate': [93], 'limiting': [95], 'losses,': [97], 'at': [99], 'expense': [101], 'increased': [103], 'These': [106, 138], 'data': [107], 'cells,': [111, 114], 'like': [112], 'adrenal': [113, 132], 'sense': [115], 'via': [117, 126], 'voltage.': [119], 'In': [120], 'DCT,': [122], 'hyperpolarization': [123], 'NCC': [125], 'kinases,': [128], 'whereas': [129], 'gland,': [133], 'it': [134], 'inhibits': [135], 'aldosterone': [136], 'secretion.': [137], 'effects': [139], 'work': [140], 'concert': [142], 'maintain': [144], 'homeostasis.': [146]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1970486445', 'counts_by_year': [{'year': 2024, 'cited_by_count': 26}, {'year': 2023, 'cited_by_count': 35}, {'year': 2022, 'cited_by_count': 53}, {'year': 2021, 'cited_by_count': 39}, {'year': 2020, 'cited_by_count': 41}, {'year': 2019, 'cited_by_count': 41}, {'year': 2018, 'cited_by_count': 40}, {'year': 2017, 'cited_by_count': 46}, {'year': 2016, 'cited_by_count': 39}, {'year': 2015, 'cited_by_count': 19}], 'updated_date': '2024-09-12T20:17:57.311832', 'created_date': '2016-06-24'}