Title: Reduced and total ascorbate in guinea pig eye tissues in response to dietary intake
Abstract: Guinea pigs were fed 5 different levels of dietary ascorbate representing a 65-fold range (O.P-52 mg animal-1 day-1). After two months on the diets, levels of reduced and total ascorbate were determined in aqueous humor, vitreous humor, lens and plasma. At low-dietary levels, proportionally higher levels of ascorbate are found in the lens than in other eye tissues.Tissue ascorbate levels began to plateau at dietary intake of approximately 11 mg animal-1 day-1. This is the amount suggested for optimal health, but it is ten times the level needed to prevent scurvy. Over 75% of the eye tissue ascorbate is in the reduced form in animals fed diets which provided 11 mg ascorbate. However, there was less than 50% reduced ascorbate in the eye tissues of the animals fed about Img ascorbate per day.
Publication Year: 1988
Publication Date: 1988-01-01
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
Access and Citation
Cited By Count: 38
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