Expression and activity of cGMP-dependent phosphodiesterases is up-regulated by lipopolysaccharide (LPS) in rat peritoneal macrophages

Name: Work Video:
Duration: 3 min 30 s
Hanna Witwicka; Marcin Kobiałka; Jakub Siednienko; Małgorzata Mitkiewicz; Wojciech Gorczyca
{'id': 'https://openalex.org/W1968217178', 'doi': 'https://doi.org/10.1016/j.bbamcr.2006.10.008', 'title': 'Expression and activity of cGMP-dependent phosphodiesterases is up-regulated by lipopolysaccharide (LPS) in rat peritoneal macrophages', 'display_name': 'Expression and activity of cGMP-dependent phosphodiesterases is up-regulated by lipopolysaccharide (LPS) in rat peritoneal macrophages', 'publication_year': 2006, 'publication_date': '2006-10-25', 'ids': {'openalex': 'https://openalex.org/W1968217178', 'doi': 'https://doi.org/10.1016/j.bbamcr.2006.10.008', 'mag': '1968217178', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/17141339'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.bbamcr.2006.10.008', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4210226410', 'display_name': 'Biochimica et Biophysica Acta (BBA) - Molecular Cell Research', 'issn_l': '0167-4889', 'issn': ['0167-4889', '1879-2596'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5079297881', 'display_name': 'Hanna Witwicka', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210163977', 'display_name': 'Ludwik Hirszfeld Institute of Immunology and Experimental Therapy', 'ror': 'https://ror.org/05b7p8k90', 'country_code': 'PL', 'type': 'facility', 'lineage': ['https://openalex.org/I4210163977', 'https://openalex.org/I99542240']}, {'id': 'https://openalex.org/I99542240', 'display_name': 'Polish Academy of Sciences', 'ror': 'https://ror.org/01dr6c206', 'country_code': 'PL', 'type': 'government', 'lineage': ['https://openalex.org/I99542240']}], 'countries': ['PL'], 'is_corresponding': False, 'raw_author_name': 'Hanna Witwicka', 'raw_affiliation_strings': ['Laboratory of Signaling Proteins, L. Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, R. Weigla 12, 53-114 Wrocław, Poland.'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Signaling Proteins, L. Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, R. Weigla 12, 53-114 Wrocław, Poland.', 'institution_ids': ['https://openalex.org/I4210163977', 'https://openalex.org/I99542240']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5017772026', 'display_name': 'Marcin Kobiałka', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I99542240', 'display_name': 'Polish Academy of Sciences', 'ror': 'https://ror.org/01dr6c206', 'country_code': 'PL', 'type': 'government', 'lineage': ['https://openalex.org/I99542240']}, {'id': 'https://openalex.org/I4210163977', 'display_name': 'Ludwik Hirszfeld Institute of Immunology and Experimental Therapy', 'ror': 'https://ror.org/05b7p8k90', 'country_code': 'PL', 'type': 'facility', 'lineage': ['https://openalex.org/I4210163977', 'https://openalex.org/I99542240']}], 'countries': ['PL'], 'is_corresponding': False, 'raw_author_name': 'Marcin Kobiałka', 'raw_affiliation_strings': ['Laboratory of Signaling Proteins, L. Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, R. Weigla 12, 53-114 Wrocław, Poland.'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Signaling Proteins, L. Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, R. Weigla 12, 53-114 Wrocław, Poland.', 'institution_ids': ['https://openalex.org/I99542240', 'https://openalex.org/I4210163977']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5001671958', 'display_name': 'Jakub Siednienko', 'orcid': 'https://orcid.org/0000-0003-2358-5876'}, 'institutions': [{'id': 'https://openalex.org/I4210163977', 'display_name': 'Ludwik Hirszfeld Institute of Immunology and Experimental Therapy', 'ror': 'https://ror.org/05b7p8k90', 'country_code': 'PL', 'type': 'facility', 'lineage': ['https://openalex.org/I4210163977', 'https://openalex.org/I99542240']}, {'id': 'https://openalex.org/I99542240', 'display_name': 'Polish Academy of Sciences', 'ror': 'https://ror.org/01dr6c206', 'country_code': 'PL', 'type': 'government', 'lineage': ['https://openalex.org/I99542240']}], 'countries': ['PL'], 'is_corresponding': False, 'raw_author_name': 'Jakub Siednienko', 'raw_affiliation_strings': ['Laboratory of Signaling Proteins, L. Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, R. Weigla 12, 53-114 Wrocław, Poland.'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Signaling Proteins, L. Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, R. Weigla 12, 53-114 Wrocław, Poland.', 'institution_ids': ['https://openalex.org/I4210163977', 'https://openalex.org/I99542240']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5048840225', 'display_name': 'Małgorzata Mitkiewicz', 'orcid': 'https://orcid.org/0000-0003-4026-3860'}, 'institutions': [{'id': 'https://openalex.org/I4210163977', 'display_name': 'Ludwik Hirszfeld Institute of Immunology and Experimental Therapy', 'ror': 'https://ror.org/05b7p8k90', 'country_code': 'PL', 'type': 'facility', 'lineage': ['https://openalex.org/I4210163977', 'https://openalex.org/I99542240']}, {'id': 'https://openalex.org/I99542240', 'display_name': 'Polish Academy of Sciences', 'ror': 'https://ror.org/01dr6c206', 'country_code': 'PL', 'type': 'government', 'lineage': ['https://openalex.org/I99542240']}], 'countries': ['PL'], 'is_corresponding': False, 'raw_author_name': 'Małgorzata Mitkiewicz', 'raw_affiliation_strings': ['Laboratory of Signaling Proteins, L. Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, R. Weigla 12, 53-114 Wrocław, Poland.'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Signaling Proteins, L. Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, R. Weigla 12, 53-114 Wrocław, Poland.', 'institution_ids': ['https://openalex.org/I4210163977', 'https://openalex.org/I99542240']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5009873745', 'display_name': 'Wojciech Gorczyca', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210163977', 'display_name': 'Ludwik Hirszfeld Institute of Immunology and Experimental Therapy', 'ror': 'https://ror.org/05b7p8k90', 'country_code': 'PL', 'type': 'facility', 'lineage': ['https://openalex.org/I4210163977', 'https://openalex.org/I99542240']}, {'id': 'https://openalex.org/I99542240', 'display_name': 'Polish Academy of Sciences', 'ror': 'https://ror.org/01dr6c206', 'country_code': 'PL', 'type': 'government', 'lineage': ['https://openalex.org/I99542240']}], 'countries': ['PL'], 'is_corresponding': False, 'raw_author_name': 'Wojciech A. Gorczyca', 'raw_affiliation_strings': ['Laboratory of Signaling Proteins, L. Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, R. Weigla 12, 53-114 Wrocław, Poland.'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Signaling Proteins, L. Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, R. Weigla 12, 53-114 Wrocław, Poland.', 'institution_ids': ['https://openalex.org/I4210163977', 'https://openalex.org/I99542240']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3380, 'currency': 'USD', 'value_usd': 3380, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.268, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 21, 'citation_normalized_percentile': {'value': 0.73766, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 87, 'max': 88}, 'biblio': {'volume': '1773', 'issue': '2', 'first_page': '209', 'last_page': '218'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12434', 'display_name': 'Phosphodiesterase function and regulation', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12434', 'display_name': 'Phosphodiesterase function and regulation', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11346', 'display_name': 'Mast cells and histamine', 'score': 0.9894, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11917', 'display_name': 'Coagulation, Bradykinin, Polyphosphates, and Angioedema', 'score': 0.9689, 'subfield': {'id': 'https://openalex.org/subfields/2716', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/phosphodiesterase-3', 'display_name': 'Phosphodiesterase 3', 'score': 0.89665437}, {'id': 'https://openalex.org/keywords/pde10a', 'display_name': 'PDE10A', 'score': 0.73900306}, {'id': 'https://openalex.org/keywords/zaprinast', 'display_name': 'Zaprinast', 'score': 0.42538446}], 'concepts': [{'id': 'https://openalex.org/C62826618', 'wikidata': 'https://www.wikidata.org/wiki/Q424304', 'display_name': 'Phosphodiesterase', 'level': 3, 'score': 0.90264624}, {'id': 'https://openalex.org/C58141971', 'wikidata': 'https://www.wikidata.org/wiki/Q906688', 'display_name': 'Phosphodiesterase 3', 'level': 4, 'score': 0.89665437}, {'id': 'https://openalex.org/C79418042', 'wikidata': 'https://www.wikidata.org/wiki/Q5864325', 'display_name': 'PDE10A', 'level': 4, 'score': 0.73900306}, {'id': 'https://openalex.org/C2778754761', 'wikidata': 'https://www.wikidata.org/wiki/Q421804', 'display_name': 'Lipopolysaccharide', 'level': 2, 'score': 0.61563164}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.5384877}, {'id': 'https://openalex.org/C74534348', 'wikidata': 'https://www.wikidata.org/wiki/Q410798', 'display_name': 'cGMP-specific phosphodiesterase type 5', 'level': 3, 'score': 0.49441314}, {'id': 'https://openalex.org/C2779244956', 'wikidata': 'https://www.wikidata.org/wiki/Q184204', 'display_name': 'Macrophage', 'level': 3, 'score': 0.45601514}, {'id': 'https://openalex.org/C53345823', 'wikidata': 'https://www.wikidata.org/wiki/Q5531554', 'display_name': 'Gene isoform', 'level': 3, 'score': 0.4310485}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.42808235}, {'id': 'https://openalex.org/C2776846068', 'wikidata': 'https://www.wikidata.org/wiki/Q6592076', 'display_name': 'Zaprinast', 'level': 4, 'score': 0.42538446}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.3641593}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.3510062}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.30209464}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.24882284}, {'id': 'https://openalex.org/C202751555', 'wikidata': 'https://www.wikidata.org/wiki/Q221681', 'display_name': 'In vitro', 'level': 2, 'score': 0.117085636}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.084441036}, {'id': 'https://openalex.org/C2776768464', 'wikidata': 'https://www.wikidata.org/wiki/Q191521', 'display_name': 'Sildenafil', 'level': 2, 'score': 0.074439734}, {'id': 'https://openalex.org/C105702510', 'wikidata': 'https://www.wikidata.org/wiki/Q514', 'display_name': 'Anatomy', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D015106', 'descriptor_name': "3',5'-Cyclic-GMP Phosphodiesterases", 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D015106', 'descriptor_name': "3',5'-Cyclic-GMP Phosphodiesterases", 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D008070', 'descriptor_name': 'Lipopolysaccharides', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D017737', 'descriptor_name': 'Macrophages, Peritoneal', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': True}, {'descriptor_ui': 'D017737', 'descriptor_name': 'Macrophages, Peritoneal', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D015854', 'descriptor_name': 'Up-Regulation', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D015106', 'descriptor_name': "3',5'-Cyclic-GMP Phosphodiesterases", 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015106', 'descriptor_name': "3',5'-Cyclic-GMP Phosphodiesterases", 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000242', 'descriptor_name': 'Cyclic AMP', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000242', 'descriptor_name': 'Cyclic AMP', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D006152', 'descriptor_name': 'Cyclic GMP', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006152', 'descriptor_name': 'Cyclic GMP', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D017869', 'descriptor_name': 'Cyclic GMP-Dependent Protein Kinases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D017869', 'descriptor_name': 'Cyclic GMP-Dependent Protein Kinases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017869', 'descriptor_name': 'Cyclic GMP-Dependent Protein Kinases', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D015971', 'descriptor_name': 'Gene Expression Regulation, Enzymologic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015971', 'descriptor_name': 'Gene Expression Regulation, Enzymologic', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D006162', 'descriptor_name': 'Guanylate Cyclase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006162', 'descriptor_name': 'Guanylate Cyclase', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D006162', 'descriptor_name': 'Guanylate Cyclase', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D007527', 'descriptor_name': 'Isoenzymes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007527', 'descriptor_name': 'Isoenzymes', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': False}, {'descriptor_ui': 'D007527', 'descriptor_name': 'Isoenzymes', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D007527', 'descriptor_name': 'Isoenzymes', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008070', 'descriptor_name': 'Lipopolysaccharides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008262', 'descriptor_name': 'Macrophage Activation', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D008262', 'descriptor_name': 'Macrophage Activation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017737', 'descriptor_name': 'Macrophages, Peritoneal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010726', 'descriptor_name': 'Phosphodiesterase Inhibitors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010726', 'descriptor_name': 'Phosphodiesterase Inhibitors', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D012333', 'descriptor_name': 'RNA, Messenger', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012333', 'descriptor_name': 'RNA, Messenger', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D012333', 'descriptor_name': 'RNA, Messenger', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017208', 'descriptor_name': 'Rats, Wistar', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013379', 'descriptor_name': 'Substrate Specificity', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013379', 'descriptor_name': 'Substrate Specificity', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D014409', 'descriptor_name': 'Tumor Necrosis Factor-alpha', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014409', 'descriptor_name': 'Tumor Necrosis Factor-alpha', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D015854', 'descriptor_name': 'Up-Regulation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015854', 'descriptor_name': 'Up-Regulation', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.bbamcr.2006.10.008', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4210226410', 'display_name': 'Biochimica et Biophysica Acta (BBA) - Molecular Cell Research', 'issn_l': '0167-4889', 'issn': ['0167-4889', '1879-2596'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/17141339', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 58, 'referenced_works': ['https://openalex.org/W1524509448', 'https://openalex.org/W1529698986', 'https://openalex.org/W1549669942', 'https://openalex.org/W1568560878', 'https://openalex.org/W1569338260', 'https://openalex.org/W1590375747', 'https://openalex.org/W1684025987', 'https://openalex.org/W1935559473', 'https://openalex.org/W1940535066', 'https://openalex.org/W1964007044', 'https://openalex.org/W1967712758', 'https://openalex.org/W1971235918', 'https://openalex.org/W1981762797', 'https://openalex.org/W1982794985', 'https://openalex.org/W1995061448', 'https://openalex.org/W1998836600', 'https://openalex.org/W2014485420', 'https://openalex.org/W2018168922', 'https://openalex.org/W2024669624', 'https://openalex.org/W2028862001', 'https://openalex.org/W2035690299', 'https://openalex.org/W2049472065', 'https://openalex.org/W2054663379', 'https://openalex.org/W2055163292', 'https://openalex.org/W2055320083', 'https://openalex.org/W2056357997', 'https://openalex.org/W2058552525', 'https://openalex.org/W2064469698', 'https://openalex.org/W2071201365', 'https://openalex.org/W2072682099', 'https://openalex.org/W2077403144', 'https://openalex.org/W2078881054', 'https://openalex.org/W2086910484', 'https://openalex.org/W2089664452', 'https://openalex.org/W2089909459', 'https://openalex.org/W2092044051', 'https://openalex.org/W2094279170', 'https://openalex.org/W2096223487', 'https://openalex.org/W2100379188', 'https://openalex.org/W2105297145', 'https://openalex.org/W2105657039', 'https://openalex.org/W2106517675', 'https://openalex.org/W2108651626', 'https://openalex.org/W2114092160', 'https://openalex.org/W2120429719', 'https://openalex.org/W2135514207', 'https://openalex.org/W2149749758', 'https://openalex.org/W2159269771', 'https://openalex.org/W2162386698', 'https://openalex.org/W2165626477', 'https://openalex.org/W2166389885', 'https://openalex.org/W2166893101', 'https://openalex.org/W2170299511', 'https://openalex.org/W2172088242', 'https://openalex.org/W2281837736', 'https://openalex.org/W2284086792', 'https://openalex.org/W2345106043', 'https://openalex.org/W61741918'], 'related_works': ['https://openalex.org/W2172022460', 'https://openalex.org/W2088741731', 'https://openalex.org/W2083980443', 'https://openalex.org/W2055222699', 'https://openalex.org/W2049076878', 'https://openalex.org/W2015050915', 'https://openalex.org/W1979725397', 'https://openalex.org/W1969505923', 'https://openalex.org/W1968848046', 'https://openalex.org/W1968217178'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1968217178', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 3}, {'year': 2016, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 4}, {'year': 2013, 'cited_by_count': 1}], 'updated_date': '2025-01-09T18:49:51.658688', 'created_date': '2016-06-24'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
