Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1964200586', 'doi': 'https://doi.org/10.1080/00218839.2006.11101331', 'title': 'Effect of venom from the Asian honeybee (<i>Apis cerana</i>Fab.) on LPS-induced nitric oxide and tumor necrosis factor-α production in RAW 264.7 Cell Line', 'display_name': 'Effect of venom from the Asian honeybee (<i>Apis cerana</i>Fab.) on LPS-induced nitric oxide and tumor necrosis factor-α production in RAW 264.7 Cell Line', 'publication_year': 2006, 'publication_date': '2006-01-01', 'ids': {'openalex': 'https://openalex.org/W1964200586', 'doi': 'https://doi.org/10.1080/00218839.2006.11101331', 'mag': '1964200586'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1080/00218839.2006.11101331', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S118045308', 'display_name': 'Journal of Apicultural Research', 'issn_l': '0021-8839', 'issn': ['0021-8839', '2078-6913'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320547', 'host_organization_name': 'Taylor & Francis', 'host_organization_lineage': ['https://openalex.org/P4310320547'], 'host_organization_lineage_names': ['Taylor & Francis'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5045589392', 'display_name': 'Sang‐Mi Han', 'orcid': 'https://orcid.org/0000-0002-6840-4509'}, 'institutions': [{'id': 'https://openalex.org/I4210090624', 'display_name': 'National Institute of Agricultural Science and Technology', 'ror': 'https://ror.org/000vy8681', 'country_code': 'KR', 'type': 'other', 'lineage': ['https://openalex.org/I4210090624']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'SangMi Han', 'raw_affiliation_strings': ['Department of Agricultural Biology, National Institute of Agricultural Science and Technology, Suwon, 441-100, Korea'], 'affiliations': [{'raw_affiliation_string': 'Department of Agricultural Biology, National Institute of Agricultural Science and Technology, Suwon, 441-100, Korea', 'institution_ids': ['https://openalex.org/I4210090624']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5034922950', 'display_name': 'Kwang-Gill Lee', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210090624', 'display_name': 'National Institute of Agricultural Science and Technology', 'ror': 'https://ror.org/000vy8681', 'country_code': 'KR', 'type': 'other', 'lineage': ['https://openalex.org/I4210090624']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'KwangGill Lee', 'raw_affiliation_strings': ['Department of Agricultural Biology, National Institute of Agricultural Science and Technology, Suwon, 441-100, Korea'], 'affiliations': [{'raw_affiliation_string': 'Department of Agricultural Biology, National Institute of Agricultural Science and Technology, Suwon, 441-100, Korea', 'institution_ids': ['https://openalex.org/I4210090624']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5109945021', 'display_name': 'Joo‐Hong Yeo', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210090624', 'display_name': 'National Institute of Agricultural Science and Technology', 'ror': 'https://ror.org/000vy8681', 'country_code': 'KR', 'type': 'other', 'lineage': ['https://openalex.org/I4210090624']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'JooHong Yeo', 'raw_affiliation_strings': ['Department of Agricultural Biology, National Institute of Agricultural Science and Technology, Suwon, 441-100, Korea'], 'affiliations': [{'raw_affiliation_string': 'Department of Agricultural Biology, National Institute of Agricultural Science and Technology, Suwon, 441-100, Korea', 'institution_ids': ['https://openalex.org/I4210090624']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5019860923', 'display_name': 'HaeYong Kweon', 'orcid': 'https://orcid.org/0000-0001-8761-4897'}, 'institutions': [{'id': 'https://openalex.org/I4210090624', 'display_name': 'National Institute of Agricultural Science and Technology', 'ror': 'https://ror.org/000vy8681', 'country_code': 'KR', 'type': 'other', 'lineage': ['https://openalex.org/I4210090624']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'HaeYong Kweon', 'raw_affiliation_strings': ['Department of Agricultural Biology, National Institute of Agricultural Science and Technology, Suwon, 441-100, Korea'], 'affiliations': [{'raw_affiliation_string': 'Department of Agricultural Biology, National Institute of Agricultural Science and Technology, Suwon, 441-100, Korea', 'institution_ids': ['https://openalex.org/I4210090624']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5109195209', 'display_name': 'Soon‐Ok Woo', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210090624', 'display_name': 'National Institute of Agricultural Science and Technology', 'ror': 'https://ror.org/000vy8681', 'country_code': 'KR', 'type': 'other', 'lineage': ['https://openalex.org/I4210090624']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'SoonOk Woo', 'raw_affiliation_strings': ['Department of Agricultural Biology, National Institute of Agricultural Science and Technology, Suwon, 441-100, Korea'], 'affiliations': [{'raw_affiliation_string': 'Department of Agricultural Biology, National Institute of Agricultural Science and Technology, Suwon, 441-100, Korea', 'institution_ids': ['https://openalex.org/I4210090624']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5079736845', 'display_name': 'Myeong-lyeol Lee', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210090624', 'display_name': 'National Institute of Agricultural Science and Technology', 'ror': 'https://ror.org/000vy8681', 'country_code': 'KR', 'type': 'other', 'lineage': ['https://openalex.org/I4210090624']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'MyeongLyeol Lee', 'raw_affiliation_strings': ['Department of Agricultural Biology, National Institute of Agricultural Science and Technology, Suwon, 441-100, Korea'], 'affiliations': [{'raw_affiliation_string': 'Department of Agricultural Biology, National Institute of Agricultural Science and Technology, Suwon, 441-100, Korea', 'institution_ids': ['https://openalex.org/I4210090624']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5109811029', 'display_name': 'Ha-Ju Baek', 'orcid': None}, 'institutions': [], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Haju Baek', 'raw_affiliation_strings': ['Gyeongsang Buk-Do Government Public Institute of Health and Environmental, Daegu, 702-702, Korea'], 'affiliations': [{'raw_affiliation_string': 'Gyeongsang Buk-Do Government Public Institute of Health and Environmental, Daegu, 702-702, Korea', 'institution_ids': []}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5022094792', 'display_name': 'Kwan‐Kyu Park', 'orcid': 'https://orcid.org/0000-0002-5317-750X'}, 'institutions': [{'id': 'https://openalex.org/I39705031', 'display_name': 'Catholic University of Daegu', 'ror': 'https://ror.org/04fxknd68', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I39705031']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'KwanKyu Park', 'raw_affiliation_strings': ['Department of Pathology, Catholic University of Daegu School of Medicine, Daegu712-702, Korea'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, Catholic University of Daegu School of Medicine, Daegu712-702, Korea', 'institution_ids': ['https://openalex.org/I39705031']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 18, 'citation_normalized_percentile': {'value': 0.787241, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 86, 'max': 87}, 'biblio': {'volume': '45', 'issue': '3', 'first_page': '131', 'last_page': '136'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T14028', 'display_name': 'Healthcare and Venom Research', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2736', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T14028', 'display_name': 'Healthcare and Venom Research', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2736', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11353', 'display_name': 'Venomous Animal Envenomation and Studies', 'score': 0.9957, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11386', 'display_name': 'Bee Products Chemical Analysis', 'score': 0.9946, 'subfield': {'id': 'https://openalex.org/subfields/1109', 'display_name': 'Insect Science'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/melittin', 'display_name': 'Melittin', 'score': 0.5457912}, {'id': 'https://openalex.org/keywords/apamin', 'display_name': 'Apamin', 'score': 0.45157686}], 'concepts': [{'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.7751786}, {'id': 'https://openalex.org/C17991360', 'wikidata': 'https://www.wikidata.org/wiki/Q21173843', 'display_name': 'Tumor necrosis factor alpha', 'level': 2, 'score': 0.6929645}, {'id': 'https://openalex.org/C519581460', 'wikidata': 'https://www.wikidata.org/wiki/Q207843', 'display_name': 'Nitric oxide', 'level': 2, 'score': 0.675957}, {'id': 'https://openalex.org/C2778754761', 'wikidata': 'https://www.wikidata.org/wiki/Q421804', 'display_name': 'Lipopolysaccharide', 'level': 2, 'score': 0.6748148}, {'id': 'https://openalex.org/C2777622882', 'wikidata': 'https://www.wikidata.org/wiki/Q417619', 'display_name': 'Nitric oxide synthase', 'level': 3, 'score': 0.60715395}, {'id': 'https://openalex.org/C2778001312', 'wikidata': 'https://www.wikidata.org/wiki/Q424512', 'display_name': 'Melittin', 'level': 3, 'score': 0.5457912}, {'id': 'https://openalex.org/C81885089', 'wikidata': 'https://www.wikidata.org/wiki/Q189082', 'display_name': 'Cell culture', 'level': 2, 'score': 0.49291945}, {'id': 'https://openalex.org/C2778690821', 'wikidata': 'https://www.wikidata.org/wiki/Q212354', 'display_name': 'Cytokine', 'level': 2, 'score': 0.47650972}, {'id': 'https://openalex.org/C2776919887', 'wikidata': 'https://www.wikidata.org/wiki/Q417260', 'display_name': 'Apamin', 'level': 3, 'score': 0.45157686}, {'id': 'https://openalex.org/C2776415932', 'wikidata': 'https://www.wikidata.org/wiki/Q48743', 'display_name': 'Western blot', 'level': 3, 'score': 0.42251766}, {'id': 'https://openalex.org/C85265743', 'wikidata': 'https://www.wikidata.org/wiki/Q885458', 'display_name': 'Blot', 'level': 3, 'score': 0.42219588}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.37722024}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.36534566}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.3404047}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.2788256}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.22940013}, {'id': 'https://openalex.org/C2779281246', 'wikidata': 'https://www.wikidata.org/wiki/Q172847', 'display_name': 'Peptide', 'level': 2, 'score': 0.08262274}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0653595}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C2992686903', 'wikidata': 'https://www.wikidata.org/wiki/Q208453', 'display_name': 'Smooth muscle', 'level': 2, 'score': 0.0}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1080/00218839.2006.11101331', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S118045308', 'display_name': 'Journal of Apicultural Research', 'issn_l': '0021-8839', 'issn': ['0021-8839', '2078-6913'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320547', 'host_organization_name': 'Taylor & Francis', 'host_organization_lineage': ['https://openalex.org/P4310320547'], 'host_organization_lineage_names': ['Taylor & Francis'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.52, 'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 39, 'referenced_works': ['https://openalex.org/W1480602137', 'https://openalex.org/W1499807205', 'https://openalex.org/W1583738817', 'https://openalex.org/W1965077361', 'https://openalex.org/W1965860042', 'https://openalex.org/W1982506950', 'https://openalex.org/W1983202594', 'https://openalex.org/W1988721729', 'https://openalex.org/W1990802251', 'https://openalex.org/W1994162099', 'https://openalex.org/W1998491594', 'https://openalex.org/W2011792575', 'https://openalex.org/W2022511082', 'https://openalex.org/W2022616319', 'https://openalex.org/W2024966528', 'https://openalex.org/W2032331774', 'https://openalex.org/W2036950083', 'https://openalex.org/W2043837854', 'https://openalex.org/W2044646390', 'https://openalex.org/W2060548975', 'https://openalex.org/W2066532062', 'https://openalex.org/W2079226821', 'https://openalex.org/W2082488061', 'https://openalex.org/W2092796713', 'https://openalex.org/W2103911193', 'https://openalex.org/W2123080797', 'https://openalex.org/W2144838215', 'https://openalex.org/W2151597802', 'https://openalex.org/W2174322658', 'https://openalex.org/W2188714688', 'https://openalex.org/W2238865560', 'https://openalex.org/W2274304013', 'https://openalex.org/W2304131176', 'https://openalex.org/W2408893854', 'https://openalex.org/W2487216908', 'https://openalex.org/W2492020276', 'https://openalex.org/W4237466519', 'https://openalex.org/W4254908445', 'https://openalex.org/W62571714'], 'related_works': ['https://openalex.org/W4242339945', 'https://openalex.org/W3024118754', 'https://openalex.org/W2765438329', 'https://openalex.org/W2751778010', 'https://openalex.org/W2466518878', 'https://openalex.org/W2085144019', 'https://openalex.org/W2073254574', 'https://openalex.org/W2040530229', 'https://openalex.org/W1981432316', 'https://openalex.org/W1968811274'], 'abstract_inverted_index': {'SummaryTo': [0], 'explain': [1], 'the': [2, 12, 32, 48, 96, 119, 127, 156, 172, 176], 'composition': [3, 46], 'of': [4, 15, 20, 34, 53, 60, 65, 93, 98, 129, 158, 175, 179], 'Asian': [5], 'honeybee': [6, 38], '(Apis': [7], 'cerana)': [8], 'venom': [9, 41], '(ABV)': [10], 'and': [11, 25, 36, 50, 71, 104, 111, 122, 125, 131, 146, 161], 'anti-inflammatory': [13, 141], 'effect': [14, 142], 'ABV.': [16, 90], 'The': [17, 63, 91], 'major': [18], 'components': [19, 178], 'ABV': [21, 35, 54, 94, 117, 138, 150, 180], 'by': [22, 78, 108, 143], 'LC': [23], 'chromatography': [24], 'SDS-PAGE': [26], 'were': [27, 106], 'identified.': [28], 'We': [29], 'demonstrated': [30], 'that': [31, 59, 137], 'component': [33], 'Western': [37], '(A.': [39], 'melifera)': [40], 'is': [42, 55], 'similar': [43], 'in': [44, 81, 113, 164], 'its': [45], 'but': [47], 'melittin': [49], 'apamin': [51], 'content': [52, 57], 'lower': [56], 'than': [58], 'A.': [61], 'melifera.': [62], 'production': [64, 157, 163], 'pro-inflammatory': [66], 'cytokines,': [67], 'nitric': [68, 100], 'oxide': [69, 101], '(NO)': [70], 'tumor': [72], 'necrosis': [73], 'factor-alpha': [74], '(TNF-α)': [75], 'was': [76], 'examined': [77], 'lipopolysaccharide': [79], '(LPS)': [80], 'a': [82], 'macrophage': [83], 'cell': [84], 'line,': [85], 'RAW': [86, 115], '264.7': [87], 'cells,': [88], 'with': [89], 'effects': [92], 'on': [95, 171], 'expression': [97], 'inducible': [99], 'synthase': [102], '(iNOS)': [103], 'TNF-α': [105, 123, 132, 147], 'investigated': [107], 'western': [109], 'blot': [110], 'RT-PCR': [112], 'LPS-stimulated': [114], '264.7.': [116], 'suppressed': [118], 'NO,': [120], 'iNOS': [121, 130, 145], 'production,': [124], 'decreased': [126], 'levels': [128], 'mRNA.': [133], 'These': [134], 'results': [135], 'suggest': [136], 'has': [139], 'an': [140], 'inhibiting': [144, 155], 'expression.': [148], 'Therefore,': [149], 'may': [151], 'be': [152], 'useful': [153], 'for': [154, 183], 'inflammatory': [159, 167], 'cytokine': [160], 'NO': [162], 'immune': [165], 'cell-mediated': [166], 'diseases.': [168], 'Further': [169], 'studies': [170], 'pharmacological': [173], 'aspects': [174], 'individual': [177], 'are': [181], 'recommended': [182], 'future': [184], 'trials.Keywords:': [185], 'bee': [186], 'venomApis': [187], 'ceranainflammationnitric': [188], 'oxideiNOSTNF-α': [189]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1964200586', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 2}, {'year': 2013, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2024-12-14T08:25:15.837318', 'created_date': '2016-06-24'}